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Volumn 20, Issue 11, 2010, Pages 1534-1544

Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMISININ; CLINDAMYCIN; LINCOSAMIDE DERIVATIVE; MEFLOQUINE; MIRINCAMYCIN; PYRIMETHAMINE; QUININE; UNCLASSIFIED DRUG;

EID: 78649245868     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.105163.110     Document Type: Article
Times cited : (60)

References (83)
  • 1
    • 64149119179 scopus 로고    scopus 로고
    • Complex inheritance of the plasmodial surface anion channel in a Plasmodium falciparum genetic cross
    • Alkhalil A, Pillai AD, Bokhari AA, Vaidya AB, Desai SA. 2009. Complex inheritance of the plasmodial surface anion channel in a Plasmodium falciparum genetic cross. Mol Microbiol 72: 459-469.
    • (2009) Mol Microbiol , vol.72 , pp. 459-469
    • Alkhalil, A.1    Pillai, A.D.2    Bokhari, A.A.3    Vaidya, A.B.4    Desai, S.A.5
  • 6
    • 24644519409 scopus 로고    scopus 로고
    • False-positive results of a Plasmodium falciparum histidine-rich protein 2-detecting malaria rapid diagnostic test due to high sensitivity in a community with fluctuating low parasite density
    • Bell DR, Wilson DW, Martin LB. 2005. False-positive results of a Plasmodium falciparum histidine-rich protein 2-detecting malaria rapid diagnostic test due to high sensitivity in a community with fluctuating low parasite density. Am J Trop Med Hyg 73: 199-203.
    • (2005) Am J Trop Med Hyg , vol.73 , pp. 199-203
    • Bell, D.R.1    Wilson, D.W.2    Martin, L.B.3
  • 9
    • 24044551679 scopus 로고    scopus 로고
    • Clustered local transmission and asymptomatic Plasmodium falciparum and Plasmodium vivax malaria infections in a recently emerged, hypoendemic Peruvian Amazon community
    • DOI 10.1186/1475-2875-4-27
    • Branch O, Casapia WM, Gamboa DV, Hernandez JN, Alava FF, Roncal N, Alvarez E, Perez EJ, Gotuzzo E. 2005. Clustered local transmission and asymptomatic Plasmodium falciparum and Plasmodium vivax malaria infections in a recently emerged, hypoendemic Peruvian Amazon community. Malar J 4: 27. doi: 10.1186/1475-2875-4-27. (Pubitemid 41214251)
    • (2005) Malaria Journal , vol.4 , pp. 27
    • Branch, O.1    Casapia, W.M.2    Gamboa, D.V.3    Hernandez, J.N.4    Alava, F.F.5    Roncal, N.6    Alvarez, E.7    Perez, E.J.8    Gotuzzo, E.9
  • 11
    • 0036227773 scopus 로고    scopus 로고
    • An rRNA mutation identifies the apicoplast as the target for clindamycin in Toxoplasma gondii
    • DOI 10.1046/j.1365-2958.2002.02825.x
    • Camps M, Arrizabalaga G, Boothroyd J. 2002. An rRNA mutation identifies the apicoplast as the target for clindamycin in Toxoplasma gondii. Mol Microbiol 43: 1309-1318. (Pubitemid 34304545)
    • (2002) Molecular Microbiology , vol.43 , Issue.5 , pp. 1309-1318
    • Camps, M.1    Arrizabalaga, G.2    Boothroyd, J.3
  • 12
    • 2942571539 scopus 로고    scopus 로고
    • The comparative RNA web (CRW) site: An online database of comparative sequence and structure information for ribosomal, intron, and other RNAs
    • doi: 10.1186/1471-2105-3-2
    • Cannone JJ, Subramanian S, Schnare MN, Collett JR, D'Souza LM, Du Y, Feng B, Lin N, Madabusi LV, Muller KM, et al. 2002. The comparative RNA web (CRW) site: An online database of comparative sequence and structure information for ribosomal, intron, and other RNAs. BMC Bioinformatics 3: 2. doi: 10.1186/1471-2105-3-2.
    • (2002) BMC Bioinformatics , vol.3 , pp. 2
    • Cannone, J.J.1    Subramanian, S.2    Schnare, M.N.3    Collett, J.R.4    D'Souza, L.M.5    Du, Y.6    Feng, B.7    Lin, N.8    Madabusi, L.V.9    Muller, K.M.10
  • 14
    • 45549092610 scopus 로고    scopus 로고
    • Genetic diversity of vaccine candidate antigens in Plasmodium falciparum isolates from the Amazon basin of Peru
    • doi: 10.1186/1475-2875-7-93
    • Chenet SM, Branch OH, Escalante AA, Lucas CM, Bacon DJ. 2008. Genetic diversity of vaccine candidate antigens in Plasmodium falciparum isolates from the Amazon basin of Peru. Malar J 7: 93. doi: 10.1186/1475-2875-7-93.
    • (2008) Malar J , vol.7 , pp. 93
    • Chenet, S.M.1    Branch, O.H.2    Escalante, A.A.3    Lucas, C.M.4    Bacon, D.J.5
  • 15
    • 0036137277 scopus 로고    scopus 로고
    • DNA sequence quality trimming and vector removal
    • Chou HH, Holmes MH. 2001. DNA sequence quality trimming and vector removal. Bioinformatics 17: 1093-1104.
    • (2001) Bioinformatics , vol.17 , pp. 1093-1104
    • Chou, H.H.1    Holmes, M.H.2
  • 18
    • 43949134849 scopus 로고    scopus 로고
    • Apicoplast translation, transcription and genome replication: Targets for antimalarial antibiotics
    • Dahl EL, Rosenthal PJ. 2008. Apicoplast translation, transcription and genome replication: Targets for antimalarial antibiotics. Trends Parasitol 24: 279-284.
    • (2008) Trends Parasitol , vol.24 , pp. 279-284
    • Dahl, E.L.1    Rosenthal, P.J.2
  • 22
    • 70449732094 scopus 로고    scopus 로고
    • Artemisinin-based combination therapies: A vital tool in efforts to eliminate malaria
    • Eastman RT, Fidock DA. 2009. Artemisinin-based combination therapies: A vital tool in efforts to eliminate malaria. Nat Rev Microbiol 7: 864-874.
    • (2009) Nat Rev Microbiol , vol.7 , pp. 864-874
    • Eastman, R.T.1    Fidock, D.A.2
  • 26
    • 77749309907 scopus 로고    scopus 로고
    • A large proportion of P. falciparum isolates in the Amazon region of Peru lack pfhrp2 and pfhrp3: Implications for malaria rapid diagnostic tests
    • doi: 10.1371/journal.pone.0008091
    • Gamboa D, Ho MF, Bendezu J, Torres K, Chiodini PL, Barnwell JW, Incardona S, Perkins M, Bell D, McCarthy J, et al. 2010. A large proportion of P. falciparum isolates in the Amazon region of Peru lack pfhrp2 and pfhrp3: Implications for malaria rapid diagnostic tests. PLoS ONE 5: e8091. doi: 10.1371/journal.pone.0008091.
    • (2010) PLoS ONE , vol.5
    • Gamboa, D.1    Ho, M.F.2    Bendezu, J.3    Torres, K.4    Chiodini, P.L.5    Barnwell, J.W.6    Incardona, S.7    Perkins, M.8    Bell, D.9    McCarthy, J.10
  • 31
    • 0013842098 scopus 로고
    • Chloroquine-resistant falciparum malaria in Thailand
    • Harinasuta T, Suntharasamai P, Viravan C. 1965. Chloroquine-resistant falciparum malaria in Thailand. Lancet 2: 657-660.
    • (1965) Lancet , vol.2 , pp. 657-660
    • Harinasuta, T.1    Suntharasamai, P.2    Viravan, C.3
  • 32
    • 0024746937 scopus 로고
    • Antibiotic resistance mutations in the chloroplast 16S and 23S rRNA genes of Chlamydomonas reinhardtii: Correlation of genetic and physical maps of the chloroplast genome
    • Harris EH, Burkhart BD, Gillham NW, Boynton JE. 1989. Antibiotic resistance mutations in the chloroplast 16S and 23S rRNA genes of Chlamydomonas reinhardtii: Correlation of genetic and physical maps of the chloroplast genome. Genetics 123: 281-292.
    • (1989) Genetics , vol.123 , pp. 281-292
    • Harris, E.H.1    Burkhart, B.D.2    Gillham, N.W.3    Boynton, J.E.4
  • 34
    • 73849103134 scopus 로고    scopus 로고
    • In vitro activity of mirincamycin (U24729A) against Plasmodium falciparum isolates from Gabon
    • Held J, Westerman R, Kremsner PG, Mordmuller B. 2010. In vitro activity of mirincamycin (U24729A) against Plasmodium falciparum isolates from Gabon. Antimicrob Agents Chemother 54: 540-542.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 540-542
    • Held, J.1    Westerman, R.2    Kremsner, P.G.3    Mordmuller, B.4
  • 35
    • 28244477359 scopus 로고    scopus 로고
    • Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6
    • DOI 10.1016/S0140-6736(05)67787-2, PII S0140673605677872
    • Jambou R, Legrand E, Niang M, Khim N, Lim P, Volney B, Ekala MT, Bouchier C, Esterre P, Fandeur T, et al. 2005. Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6. Lancet 366: 1960-1963. (Pubitemid 41713986)
    • (2005) Lancet , vol.366 , Issue.9501 , pp. 1960-1963
    • Jambou, R.1    Legrand, E.2    Niang, M.3    Khim, N.4    Lim, P.5    Volney, B.6    Ekala, M.T.7    Bouchier, C.8    Esterre, P.9    Fandeur, T.10    Mercereau-Puijalon, O.11
  • 40
    • 65349182925 scopus 로고    scopus 로고
    • Unified parasite lactate dehydrogenase and histidine-rich protein ELISA for quantification of Plasmodium falciparum
    • Martin SK, Rajasekariah GH, Awinda G, Waitumbi J, Kifude C. 2009. Unified parasite lactate dehydrogenase and histidine-rich protein ELISA for quantification of Plasmodium falciparum. Am J Trop Med Hyg 80: 516-522.
    • (2009) Am J Trop Med Hyg , vol.80 , pp. 516-522
    • Martin, S.K.1    Rajasekariah, G.H.2    Awinda, G.3    Waitumbi, J.4    Kifude, C.5
  • 43
  • 46
    • 58149333420 scopus 로고    scopus 로고
    • Apicoplast and mitochondrion in gametocytogenesis of Plasmodium falciparum
    • Okamoto N, Spurck TP, Goodman CD, McFadden GI. 2009. Apicoplast and mitochondrion in gametocytogenesis of Plasmodium falciparum. Eukaryot Cell 8: 128-132.
    • (2009) Eukaryot Cell , vol.8 , pp. 128-132
    • Okamoto, N.1    Spurck, T.P.2    Goodman, C.D.3    McFadden, G.I.4
  • 47
    • 67349124872 scopus 로고    scopus 로고
    • The global portfolio of new antimalarial medicines under development
    • Olliaro P, Wells TN. 2009. The global portfolio of new antimalarial medicines under development. Clin Pharmacol Ther 85: 584-595.
    • (2009) Clin Pharmacol Ther , vol.85 , pp. 584-595
    • Olliaro, P.1    Wells, T.N.2
  • 48
    • 0031596103 scopus 로고    scopus 로고
    • Comparison of the ParaSight-F test and the ICT Malaria Pf test with the polymerase chain reaction for the diagnosis of Plasmodium falciparum malaria in travellers
    • DOI 10.1016/S0035-9203(98)90730-1
    • Pieroni P, Mills CD, Ohrt C, Harrington MA, Kain KC. 1998. Comparison of the ParaSight-F test and the ICT Malaria Pf test with the polymerase chain reaction for the diagnosis of Plasmodium falciparum malaria in travellers. Trans R Soc Trop Med Hyg 92: 166-169. (Pubitemid 28200792)
    • (1998) Transactions of the Royal Society of Tropical Medicine and Hygiene , vol.92 , Issue.2 , pp. 166-169
    • Pieroni, P.1    Mills, C.D.2    Ohrt, C.3    Harrington, M.A.4    Kain, K.C.5
  • 50
    • 65549119262 scopus 로고    scopus 로고
    • Disruption of a Plasmodium falciparum multidrug resistance-associated protein (PfMRP) alters its fitness and transport of antimalarial drugs and glutathione
    • Raj DK, Mu J, Jiang H, Kabat J, Singh S, Sullivan M, Fay MP, McCutchan TF, Su XZ. 2009. Disruption of a Plasmodium falciparum multidrug resistance-associated protein (PfMRP) alters its fitness and transport of antimalarial drugs and glutathione. J Biol Chem 284: 7687-7696.
    • (2009) J Biol Chem , vol.284 , pp. 7687-7696
    • Raj, D.K.1    Mu, J.2    Jiang, H.3    Kabat, J.4    Singh, S.5    Sullivan, M.6    Fay, M.P.7    McCutchan, T.F.8    Su, X.Z.9
  • 51
    • 33846026771 scopus 로고    scopus 로고
    • Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum
    • DOI 10.1128/AAC.00808-06
    • Ramya TN, Mishra S, Karmodiya K, Surolia N, Surolia A. 2007. Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. Antimicrob Agents Chemother 51: 307-316. (Pubitemid 46047720)
    • (2007) Antimicrobial Agents and Chemotherapy , vol.51 , Issue.1 , pp. 307-316
    • Ramya, T.N.C.1    Mishra, S.2    Karmodiya, K.3    Surolia, N.4    Surolia, A.5
  • 52
    • 0030829371 scopus 로고    scopus 로고
    • Variations in frequencies of drug resistance in Plasmodium falciparum
    • Rathod PK, McErlean T, Lee PC. 1997. Variations in frequencies of drug resistance in Plasmodium falciparum. Proc Natl Acad Sci 94: 9389-9393.
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 9389-9393
    • Rathod, P.K.1    McErlean, T.2    Lee, P.C.3
  • 53
    • 42449112810 scopus 로고    scopus 로고
    • Update on macrolide-lincosamide-streptogramin, ketolide, and oxazolidinone resistance genes
    • Roberts MC. 2008. Update on macrolide-lincosamide-streptogramin, ketolide, and oxazolidinone resistance genes. FEMS Microbiol Lett 282: 147-159.
    • (2008) FEMS Microbiol Lett , vol.282 , pp. 147-159
    • Roberts, M.C.1
  • 54
    • 4143103433 scopus 로고    scopus 로고
    • Intercontinental spread of pyrimethamine-resistant malaria
    • doi: 10.1126/science.1098876
    • Roper C, Pearce R, Nair S, Sharp B, Nosten F, Anderson T. 2004. Intercontinental spread of pyrimethamine-resistant malaria. Science 305: 1124. doi: 10.1126/science.1098876.
    • (2004) Science , vol.305 , pp. 1124
    • Roper, C.1    Pearce, R.2    Nair, S.3    Sharp, B.4    Nosten, F.5    Anderson, T.6
  • 59
    • 0021805735 scopus 로고
    • Enhancement of the curative activity of primaquine by concomitant administration of mirincamycin
    • Schmidt LH. 1985. Enhancement of the curative activity of primaquine by concomitant administration of mirincamycin. Antimicrob Agents Chemother 27: 151-157.
    • (1985) Antimicrob Agents Chemother , vol.27 , pp. 151-157
    • Schmidt, L.H.1
  • 60
    • 0037020024 scopus 로고    scopus 로고
    • Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations
    • Sidhu AB, Verdier-Pinard D, Fidock DA. 2002. Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations. Science 298: 210-213.
    • (2002) Science , vol.298 , pp. 210-213
    • Sidhu, A.B.1    Verdier-Pinard, D.2    Fidock, D.A.3
  • 61
    • 23744435838 scopus 로고    scopus 로고
    • Pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum
    • Sidhu AB, Valderramos SG, Fidock DA. 2005. pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum. Mol Microbiol 57: 913-926.
    • (2005) Mol Microbiol , vol.57 , pp. 913-926
    • Sidhu, A.B.1    Valderramos, S.G.2    Fidock, D.A.3
  • 62
    • 33746302565 scopus 로고    scopus 로고
    • Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin
    • Sidhu AB, Uhlemann AC, Valderramos SG, Valderramos JC, Krishna S, Fidock DA. 2006. Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin. J Infect Dis 194: 528-535.
    • (2006) J Infect Dis , vol.194 , pp. 528-535
    • Sidhu, A.B.1    Uhlemann, A.C.2    Valderramos, S.G.3    Valderramos, J.C.4    Krishna, S.5    Fidock, D.A.6
  • 63
    • 34047255258 scopus 로고    scopus 로고
    • In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin
    • Sidhu AB, Sun Q, Nkrumah LJ, Dunne MW, Sacchettini JC, Fidock DA. 2007. In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin. J Biol Chem 282: 2494-2504.
    • (2007) J Biol Chem , vol.282 , pp. 2494-2504
    • Sidhu, A.B.1    Sun, Q.2    Nkrumah, L.J.3    Dunne, M.W.4    Sacchettini, J.C.5    Fidock, D.A.6
  • 64
    • 33947398002 scopus 로고    scopus 로고
    • Minimus: A fast, lightweight genome assembler
    • doi: 10.1186/1471-2105-8-64
    • Sommer DD, Delcher AL, Salzberg SL, Pop M. 2007. Minimus: A fast, lightweight genome assembler. BMC Bioinformatics 8: 64. doi: 10.1186/1471-2105-8-64.
    • (2007) BMC Bioinformatics , vol.8 , pp. 64
    • Sommer, D.D.1    Delcher, A.L.2    Salzberg, S.L.3    Pop, M.4
  • 65
    • 34250744253 scopus 로고    scopus 로고
    • Genetic linkage and association analyses for trait mapping in Plasmodium falciparum
    • DOI 10.1038/nrg2126, PII NRG2126
    • Su X, Hayton K, Wellems TE. 2007. Genetic linkage and association analyses for trait mapping in Plasmodium falciparum. Nat Rev Genet 8: 497-506. (Pubitemid 46955213)
    • (2007) Nature Reviews Genetics , vol.8 , Issue.7 , pp. 497-506
    • Su, X.1    Hayton, K.2    Wellems, T.E.3
  • 66
    • 0030824646 scopus 로고    scopus 로고
    • Direct PCR amplification and sequence analysis of extrachromosomal Plasmodium DNA from dried blood spots
    • Tan TM, Nelson JS, Ng HC, Ting RC, Kara UA. 1997. Direct PCR amplification and sequence analysis of extrachromosomal Plasmodium DNA from dried blood spots. Acta Trop 68: 105-114.
    • (1997) Acta Trop , vol.68 , pp. 105-114
    • Tan, T.M.1    Nelson, J.S.2    Ng, H.C.3    Ting, R.C.4    Kara, U.A.5
  • 67
    • 67349266986 scopus 로고    scopus 로고
    • Optimizing comparative genomic hybridization probes for genotyping and SNP detection in Plasmodium falciparum
    • Tan JC, Patel JJ, Tan A, Blain JC, Albert TJ, Lobo NF, Ferdig MT. 2009. Optimizing comparative genomic hybridization probes for genotyping and SNP detection in Plasmodium falciparum. Genomics 93: 543-550.
    • (2009) Genomics , vol.93 , pp. 543-550
    • Tan, J.C.1    Patel, J.J.2    Tan, A.3    Blain, J.C.4    Albert, T.J.5    Lobo, N.F.6    Ferdig, M.T.7
  • 68
    • 0017892683 scopus 로고
    • Cultivation of malarial parasites
    • Trager W, Jenson JB. 1978. Cultivation of malarial parasites. Nature 273: 621-622.
    • (1978) Nature , vol.273 , pp. 621-622
    • Trager, W.1    Jenson, J.B.2
  • 69
    • 76149120388 scopus 로고    scopus 로고
    • AutoDock Vina: Improving the speed and accuracy of docking with a newscoring function, efficient optimization, and multithreading
    • Trott, O, Olson, AJ. 2009. AutoDock Vina: Improving the speed and accuracy of docking with a newscoring function, efficient optimization, and multithreading. J Comput Chem 31: 455-461.
    • (2009) J Comput Chem , vol.31 , pp. 455-461
    • Trott, O.1    Olson, A.J.2
  • 70
    • 17444421169 scopus 로고    scopus 로고
    • BK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance
    • DOI 10.1016/j.cell.2005.02.005
    • Tu D, Blaha G, Moore PB, Steitz TA. 2005. Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance. Cell 121: 257-270. (Pubitemid 40546393)
    • (2005) Cell , vol.121 , Issue.2 , pp. 257-270
    • Tu, D.1    Blaha, G.2    Moore, P.B.3    Steitz, T.A.4
  • 73
    • 0035160878 scopus 로고    scopus 로고
    • Macrolide resistance conferred by base substitutions in 23S rRNA
    • DOI 10.1128/AAC.45.1.1-12.2001
    • Vester B, Douthwaite S. 2001. Macrolide resistance conferred by base substitutions in 23S rRNA. Antimicrob Agents Chemother 45: 1-12. (Pubitemid 32039086)
    • (2001) Antimicrobial Agents and Chemotherapy , vol.45 , Issue.1 , pp. 1-12
    • Vester, B.1    Douthwaite, S.2
  • 77
    • 1842713046 scopus 로고    scopus 로고
    • Genetic and metabolic analysis of folate salvage in the human malaria parasite Plasmodium falciparum
    • DOI 10.1016/j.molbiopara.2004.01.008, PII S0166685104000301
    • Wang P, Nirmalan N, Wang Q, Sims PF, Hyde JE. 2004b. Genetic and metabolic analysis of folate salvage in the human malaria parasite Plasmodium falciparum. Mol Biochem Parasitol 135: 77-87. (Pubitemid 38470077)
    • (2004) Molecular and Biochemical Parasitology , vol.135 , Issue.1 , pp. 77-87
    • Wang, P.1    Nirmalan, N.2    Wang, Q.3    Sims, P.F.G.4    Hyde, J.E.5
  • 79
    • 53649096054 scopus 로고    scopus 로고
    • Malaria research in the post-genomic era
    • Winzeler EA. 2008. Malaria research in the post-genomic era. Nature 455: 751-756.
    • (2008) Nature , vol.455 , pp. 751-756
    • Winzeler, E.A.1
  • 82
    • 0037130254 scopus 로고    scopus 로고
    • Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum
    • DOI 10.1038/nature00813
    • Wootton JC, Feng X, Ferdig MT, Cooper RA, Mu J, Baruch DI, Magill AJ, Su XZ. 2002. Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum. Nature 418: 320-323. (Pubitemid 34790681)
    • (2002) Nature , vol.418 , Issue.6895 , pp. 320-323
    • Wootton, J.C.1    Feng, X.2    Ferdig, M.T.3    Cooper, R.A.4    Mu, J.5    Baruch, D.I.6    Magill, A.J.7    Su, X.-Z.8


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