Genetic diversity of vaccine candidate antigens in Plasmodium falciparum isolates from the Amazon basin of Peru

Malaria Journal

Volumn 7, Issue , 2008, Pages

  Chenet, Stella M ^a   Branch, OraLee H ^b   Escalante, Ananias A ^c   Lucas, Carmen M ^a   Bacon, David J ^a,d  

^a Virology Program   (Peru)

^b and Clinical Center   (United States)

^c ARIZONA STATE UNIVERSITY   (United States)

^d Navy Environmental and Preventive Medicine Unit 2   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APICAL MEMBRANE ANTIGEN 1; BACTERIAL VACCINE; CIRCUMSPOROZOITE PROTEIN; MEROZOITE SURFACE PROTEIN 1; PLASMODIUM FALCIPARUM VACCINE; EPITOPE; PARASITE ANTIGEN;

ALLELE; ARTICLE; B LYMPHOCYTE; BACTERIAL STRAIN; CONTROLLED STUDY; DNA POLYMORPHISM; DNA SEQUENCE; GENETIC VARIABILITY; HAPLOTYPE; HETEROZYGOSITY; NONHUMAN; PERU; PLASMODIUM FALCIPARUM; T LYMPHOCYTE; ANIMAL; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETICS; HUMAN; SEQUENCE HOMOLOGY;

ANIMALS; ANTIGENS, PROTOZOAN; EPITOPES, B-LYMPHOCYTE; EPITOPES, T-LYMPHOCYTE; GENE FREQUENCY; HAPLOTYPES; HUMANS; PERU; PLASMODIUM FALCIPARUM; POLYMORPHISM, GENETIC; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 45549092610     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-7-93     Document Type: Article

References (53)

1. Extensive polymorphism and ancient origin of Plasmodium falciparum. AL Hughes F Verra, Trends Parasitol 2002 18 348 351 10.1016/S1471-4922(02)02290-0 12377283
2. Malaria vaccines: if at first you don't succeed. JE Tongren F Zavala DS Roos EM Riley, Trends Parasitol 2004 20 604 610 10.1016/j.pt.2004.09.005 15522671
3. Genetic polymorphism and natural selection in the malaria parasite Plasmodium falciparum. AA Escalante AA Lal FJ Ayala, Genetics 1998 149 189 202 9584096
4. Antisporozoite vaccine for malaria: experimental basis and current status. RS Nussenzweig V Nussenzweig, Rev Infect Dis 1989 11 Suppl 3 S579 585 2669101
5. Are Extensive T Cell Epitope Polymorphisms in the Plasmodium falciparum Circumsporozoite Antigen, a Leading Sporozoite Vaccine Candidate, Selected by Immune Pressure? C Kumkhaek K Phra-ek L Renia P Singhasivanon S Looareesuwan C Hirunpetcharat NJ White A Brockman AC Gruner N Lebrun, J Immunol 2005 175 3935 3939 16148140
6. Protective efficacy of the RTS,S/AS02 Plasmodium falciparum malaria vaccine is not strain specific. A Alloueche P Milligan DJ Conway M Pinder K Bojang T Doherty N Tornieporth J Cohen BM Greenwood, Am J Trop Med Hyg 2003 68 97 101 12556156
7. Sequence variation in the T-cell epitopes of the Plasmodium falciparum circumsporozoite protein among field isolates is temporally stable: a 5-year longitudinal study in southern Vietnam. A Jalloh H van Thien MU Ferreira J Ohashi H Matsuoka T Kanbe A Kikuchi F Kawamoto, J Clin Microbiol 2006 44 1229 1235 16597843 10.1128/JCM.44.4.1229-1235.2006
8. High-throughput sequence typing of T-cell epitope polymorphisms in Plasmodium falciparum circumsporozoite protein. A Alloueche H Silveira DJ Conway K Bojang T Doherty J Cohen M Pinder BM Greenwood, Mol Biochem Parasitol 2000 106 273 282 10.1016/S0166-6851(99)00221-2 10699256
9. A study of genetic diversity in the gene encoding the circumsporozoite protein (CSP) of Plasmodium falciparum from different transmission areas-XVI. Asembo Bay Cohort Project. AA Escalante HM Grebert R Isea IF Goldman L Basco M Magris S Biswas S Kariuki AA Lal, Mol Biochem Parasitol 2002 125 83 90 12467976 10.1016/S0166-6851(02)00216-5
10. Genetic diversity of T-helper cell epitopic regions of circumsporozoite protein of Plasmodium falciparum isolates from India. PR Bhattacharya V Bhatia CR Pillai, Trans R Soc Trop Med Hyg 2006 100 395 400 10.1016/j.trstmh.2005.07. 012 16288791
11. Peptide-based subunit vaccines against pre-erythrocytic stages of malaria parasites. M Tsuji F Zavala, Mol Immunol 2001 38 433 442 10.1016/S0161-5890(01) 00079-7 11741693
12. Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial. PL Alonso J Sacarlal JJ Aponte A Leach E Macete J Milman I Mandomando B Spiessens C Guinovart M Espasa, Lancet 2004 364 1411 1420 10.1016/S0140-6736(04)17223-1 15488216
13. Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial. PL Alonso J Sacarlal JJ Aponte A Leach E Macete P Aide B Sigauque J Milman I Mandomando Q Bassat, Lancet 2005 366 2012 2018 10.1016/S0140-6736(05)67669-6 16338450
14. Shortening and modifying the 1513 MSP-1 peptide's alpha-helical region induces protection against malaria. F Espejo A Bermudez E Torres M Urquiza R Rodriguez Y Lopez ME Patarroyo, Biochem Biophys Res Commun 2004 315 418 427 10.1016/j.bbrc.2004.01.072 14766224
15. Genetic diversity in the Block 2 region of the merozoite surface protein 1 (MSP-1) of Plasmodium falciparum: additional complexity and selection and convergence in fragment size polymorphism. SL Takala AA Escalante OH Branch S Kariuki S Biswas SC Chaiyaroj AA Lal, Infect Genet Evol 2006 6 417 424 16517218 10.1016/j.meegid.2006.01.009
16. Sequence diversity and evolution of the malaria vaccine candidate merozoite surface protein-1 (MSP-1) of Plasmodium falciparum. MU Ferreira WL Ribeiro AP Tonon F Kawamoto SM Rich, Gene 2003 304 65 75 10.1016/S0378-1119(02) 01180-0 12568716
17. Longitudinal study of Plasmodium falciparum polymorphic antigens in a malaria-endemic population. DJ Conway BM Greenwood JS McBride, Infect Immun 1992 60 1122 1127 1371764
18. Antibodies to the N-terminal block 2 of Plasmodium falciparum merozoite surface protein 1 are associated with protection against clinical malaria. DR Cavanagh D Dodoo L Hviid JA Kurtzhals TG Theander BD Akanmori S Polley DJ Conway K Koram JS McBride, Infect Immun 2004 72 6492 6502 15501780 10.1128/IAI.72.11.6492-6502.2004
19. Update on the clinical development of candidate malaria vaccines. WR Ballou M Arevalo-Herrera D Carucci TL Richie G Corradin C Diggs P Druilhe BK Giersing A Saul DG Heppner, Am J Trop Med Hyg 2004 71 239 247 15331843
20. Immunisation with recombinant AMA-1 protects mice against infection with Plasmodium chabaudi. RF Anders PE Crewther S Edwards M Margetts ML Matthew B Pollock D Pye, Vaccine 1998 16 240 247 10.1016/S0264-410X(97)88331-4 9607037
21. Protective immune responses to apical membrane antigen 1 of Plasmodium chabaudi involve recognition of strain-specific epitopes. PE Crewther ML Matthew RH Flegg RF Anders, Infect Immun 1996 64 3310 3317 8757869
22. The most polymorphic residue on Plasmodium falciparum apical membrane antigen 1 determines binding of an invasion-inhibitory antibody. AM Coley K Parisi R Masciantonio J Hoeck JL Casey VJ Murphy KS Harris AH Batchelor RF Anders M Foley, Infect Immun 2006 74 2628 2636 16622199 10.1128/IAI.74.5.2628- 2636.2006
23. Polymorphism in the gene encoding the apical membrane antigen-1 (AMA-1) of Plasmodium falciparum. X. Asembo Bay Cohort Project. AA Escalante HM Grebert SC Chaiyaroj M Magris S Biswas BL Nahlen AA Lal, Mol Biochem Parasitol 2001 113 279 287 11295182 10.1016/S0166-6851(01)00229-8
24. Geographical structure of diversity and differences between symptomatic and asymptomatic infections for Plasmodium falciparum vaccine candidate AMA1. A Cortes M Mellombo I Mueller A Benet JC Reeder RF Anders, Infect Immun 2003 71 1416 1426 12595459 10.1128/IAI.71.3.1416-1426.2003
25. Diversity of the vaccine candidate AMA-1 of Plasmodium falciparum. VM Marshall L Zhang RF Anders RL Coppel, Mol Biochem Parasitol 1996 77 109 113 10.1016/0166-6851(96)02583-2 8784778
26. Molecular characterisation of Plasmodium reichenowi apical membrane antigen-1 (AMA-1), comparison with P. falciparum AMA-1, and antibody-mediated inhibition of red cell invasion. CH Kocken DL Narum A Massougbodji B Ayivi MA Dubbeld A van der Wel DJ Conway A Sanni AW Thomas, Mol Biochem Parasitol 2000 109 147 156 10.1016/S0166-6851(00)00250-4 10960173
27. T-cell immunity to peptide epitopes of liver-stage antigen 1 in an area of Papua New Guinea in which malaria is holoendemic. M Connelly CL King K Bucci S Walters B Genton MP Alpers M Hollingdale JW Kazura, Infect Immun 1997 65 5082 5087 9393799
28. Age-dependent enhancement of IFN-gamma responses to Plasmodium falciparum liver stage antigen-1 T cell epitopes. M Bongartz P Rezbach S Borrmann MR Hollingdale PG Kremsner AJ Luty, Parasitol Res 2002 2002 Aug 1021. 12444460
29. Cooperative domains define a unique host cell-targeting signal in Plasmodium falciparum-infected erythrocytes. C Lopez-Estrano S Bhattacharjee T Harrison K Haldar, Proc Natl Acad Sci USA 2003 12003 Sep 12426. 14514891
30. Characterization of Plasmodium falciparum sporozoite surface protein 2. WO Rogers A Malik S Mellouk K Nakamura MD Rogers A Szarfman DM Gordon AK Nussler M Aikawa SL Hoffman, Proc Natl Acad Sci USA 1992 89 9176 9180 1409621 10.1073/pnas.89.19.9176
31. Plasmodium falciparum: binding studies of peptide derived from the sporozoite surface protein 2 to Hep G2 cells. R Lopez H Curtidor M Urquiza J Garcia A Puentes J Suarez M Ocampo R Vera LE Rodriguez F Castillo, J Pept Res 2001 58 285 292 10.1034/j.1399-3011.2001.00902.x 11606213
32. HLA-A*0201 restricted CD8+ T-lymphocyte responses to malaria: identification of new Plasmodium falciparum epitopes by IFN-gamma ELISPOT. JM Gonzalez K Peter F Esposito I Nebie JM Tiercy A Bonelo M Arevalo-Herrera D Valmori P Romero S Herrera, Parasite Immunol 2000 22 501 514 10.1046/j.1365-3024.2000.00331.x 11012976
33. Clustered local transmission and asymptomatic Plasmodium falciparum and Plasmodium vivax malaria infections in a recently emerged, hypoendemic Peruvian Amazon community. O Branch WM Casapia DV Gamboa JN Hernandez FF Alava N Roncal E Alvarez EJ Perez E Gotuzzo, Malar J 2005 4 27 15975146 10.1186/1475-2875-4-27
34. Development of RTS,S/AS02: a purified subunit-based malaria vaccine candidate formulated with a novel adjuvant. N Garcon DG Heppner J Cohen, Expert Rev Vaccines 2003 2 231 238 10.1586/14760584.2.2.231 12899574
35. MEGA2: molecular evolutionary genetics analysis software. S Kumar K Tamura IB Jakobsen M Nei, Bioinformatics 2001 17 1244 1245 10.1093/ bioinformatics/17.12.1244 11751241
36. Molecular Evoultionary Genetics. M Nei, Columbia Univ Press 1987
37. A simple method for estimating average number of nucleotide substitutions within and between populations from restriction data. MaJCM Nei, Genetics 1990 125 873 879 1975792
38. DnaSP, DNA polymorphism analyses by the coalescent and other methods. J Rozas JC Sanchez-DelBarrio X Messeguer R Rozas, Bioinformatics 2003 19 2496 2497 10.1093/bioinformatics/btg359 14668244
39. Origin and dissemination of Plasmodium falciparum drug-resistance mutations in South America. JF Cortese A Caraballo CE Contreras CV Plowe, J Infect Dis 2002 2002 Sep 1009.
40. Genetic relatedness of Plasmodium falciparum isolates and the origin of allelic diversity at the merozoite surface protein-1 (MSP-1) locus in Brazil and Vietnam. EH Hoffmann PE Ribolla MU Ferreira, Malar J 2003 2 24 12941155 10.1186/1475-2875-2-24
41. Restricted T-cell epitope diversity in the circumsporozoite protein from Plasmodium falciparum populations prevalent in Iran. S Zakeri M Avazalipoor AA Mehrizi ND Djadid G Snounou, Am J Trop Med Hyg 2007 76 1046 1051 17556609
42. Genetic distance in housekeeping genes between Plasmodium falciparum and Plasmodium reichenowi and within P. falciparum. K Tanabe N Sakihama T Hattori L Ranford-Cartwright I Goldman AA Escalante AA Lal, J Mol Evol 2004 59 687 694 10.1007/s00239-004-2662-3 15693624
43. Differential evidence of natural selection on two leading sporozoite stage malaria vaccine candidate antigens. GD Weedall BM Preston AW Thomas CJ Sutherland DJ Conway, Int J Parasitol 2007 37 77 85 10.1016/j.ijpara.2006.09.001 17046771
44. Allelic variation in the circumsporozoite protein of Plasmodium falciparum from Thai field isolates. S Jongwutiwes K Tanabe MK Hughes H Kanbara AL Hughes, Am J Trop Med Hyg 1994 51 659 668 7985759
45. Safety and immunogenicty of RTS,S/AS02A candidate malaria vaccine in Gambian children. KA Bojang F Olodude M Pinder O Ofori-Anyinam L Vigneron S Fitzpatrick F Njie A Kassanga A Leach J Milman, Vaccine 2005 23 4148 4157 10.1016/j.vaccine.2005.03.019 15964483
46. A longitudinal study of type-specific antibody responses to Plasmodium falciparum merozoite surface protein-1 in an area of unstable malaria in Sudan. DR Cavanagh IM Elhassan C Roper VJ Robinson H Giha AA Holder L Hviid TG Theander DE Arnot JS McBride, J Immunol 1998 161 347 359 9647243
47. Plasmodium falciparum: limited genetic diversity of MSP-2 in isolates circulating in Brazilian endemic areas. S Sallenave-Sales MF Ferreira-da-Cruz CP Faria C Cerruti Jr CT Daniel-Ribeiro MG Zalis, Exp Parasitol 2003 103 127 135 10.1016/S0014-4894(03)00091-2 12880589
48. Plasmodium falciparum: allelic variation in the merozoite surface protein 1 gene in wild isolates from southern Vietnam. O Kaneko M Kimura F Kawamoto MU Ferreira K Tanabe, Exp Parasitol 1997 86 45 57 10.1006/expr.1997.4147 9149240
49. A comparative study of the genetic diversity of the 42 kDa fragment of the merozoite surface protein 1 in Plasmodium falciparum and P. vivax. MA Pacheco AC Poe WE Collins AA Lal K Tanabe SK Kariuki V Udhayakumar AA Escalante, Infect Genet Evol 2007 7 180 187 17010678 10.1016/j.meegid.2006.08.002
50. Dynamics of polymorphism in a malaria vaccine antigen at a vaccine-testing site in mali. SL Takala D Coulibaly MA Thera A Dicko DL Smith AB Guindo AK Kone K Traore A Ouattara AA Djimde, PLoS Med 2007 4 e93 17355170 10.1371/journal.pmed.0040093
51. Research note: HLA degenerate T-cell epitopes from Plasmodium falciparum liver stage-specific antigen 1 (LSA-1) are highly conserved in isolates from geographically distinct areas. M Ravichandran DL Doolan J Cox-Singh SL Hoffman B Singh, Parasite Immunol 2000 22 469 473 10.1046/j.1365-3024.2000.00324.x 10972854
52. Development of two monoclonal antibodies against Plasmodium falciparum sporozoite surface protein 2 and mapping of B-cell epitopes. Y Charoenvit V Fallarme WO Rogers JB Sacci Jr M Kaur JC Aguiar LF Yuan G Corradin E Andersen B Wizel, Infect Immun 1997 65 3430 3437 9234808
53. The circumsporozoite protein is an immunodominant protective antigen in irradiated sporozoites. KA Kumar G Sano S Boscardin RS Nussenzweig MC Nussenzweig F Zavala V Nussenzweig, Nature 2006 444 937 940 10.1038/nature05361 17151604