메뉴 건너뛰기




Volumn 43, Issue 5, 2002, Pages 1309-1318

An rRNA mutation identifies the apicoplast as the target for clindamycin in Toxoplasma gondii

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL; CLINDAMYCIN; DOXYCYCLINE; MACROLIDE; RIBOSOME DNA; RIBOSOME RNA;

EID: 0036227773     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2002.02825.x     Document Type: Article
Times cited : (94)

References (43)
  • 2
    • 0029933923 scopus 로고    scopus 로고
    • Free-radical-induced mutation vs. redox regulation: Costs and benefits of genes in organelles
    • (1996) J Mol Evol , vol.42 , pp. 482-492
    • Allen, J.F.1    Raven, J.A.2
  • 7
    • 0026601409 scopus 로고
    • Functional interactions within 23S rRNA involving the peptidyltransferase center
    • (1992) J Bacteriol , vol.174 , pp. 1333-1338
    • Douthwaite, S.1
  • 8
    • 0026660662 scopus 로고
    • Interaction of the antibiotics clindamycin and lincomycin with Escherichia coli 23S ribosomal RNA
    • (1992) Nucleic Acids Res , vol.20 , pp. 4717-4720
    • Douthwaite, S.1
  • 9
    • 0027248565 scopus 로고
    • Erythromycin binding is reduced in ribosomes with conformational alterations in the 23S rRNA peptidyl transferase loop
    • (1993) J Mol Biol , vol.232 , pp. 725-731
    • Douthwaite, S.1    Aagaard, C.2
  • 16
    • 0027347075 scopus 로고
    • Sequence analysis of mitochondrial chloramphenicol resistance mutations in Chinese hamster cells
    • (1993) Mamm Genome , vol.4 , pp. 271-275
    • Howell, N.1    Kubacka, I.2
  • 26
    • 0023604799 scopus 로고
    • Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA
    • (1987) Biochimie , vol.69 , pp. 879-884
    • Moazed, D.1    Noller, H.F.2
  • 33
    • 0027479899 scopus 로고
    • Primary structure of the dihydrofolate reductase-thymidylate synthase gene from Toxoplasma gondii
    • (1993) J Biol Chem , vol.268 , pp. 6269-6280
    • Roos, D.S.1
  • 34
    • 0032988608 scopus 로고    scopus 로고
    • The apicoplast as a potential therapeutic target in Toxoplasma and other apicomplexan parasites: Some additional thoughts
    • letter; comment
    • (1999) Parasitol Today , vol.15 , pp. 41
    • Roos, D.S.1
  • 40
    • 0028809378 scopus 로고
    • Interconnection between organellar functions, development and drug resistance in the protozoan parasite, Toxoplasma gondii
    • (1995) Int J Parasitol , vol.25 , pp. 1293-1299
    • Tomavo, S.1    Boothroyd, J.C.2
  • 41
    • 0024114860 scopus 로고
    • The importance of highly conserved nucleotides in the binding region of chloramphenicol at the peptidyl transfer centre of Escherichia coli 23S ribosomal RNA
    • (1988) EMBO J , vol.7 , pp. 3577-3587
    • Vester, B.1    Garrett, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.