-
1
-
-
0345276632
-
Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells
-
Aicher A, Heeschen C, Mildner-Rihm C, Urbich C, Ihling C, Technau-Ihling K, Zeiher AM, and Dimmeler S. Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells. Nat Med 9: 1370-1376, 2003.
-
(2003)
Nat Med
, vol.9
, pp. 1370-1376
-
-
Aicher, A.1
Heeschen, C.2
Mildner-Rihm, C.3
Urbich, C.4
Ihling, C.5
Technau-Ihling, K.6
Zeiher, A.M.7
Dimmeler, S.8
-
2
-
-
0032698316
-
Cyto-kine-mediated apoptosis in cardiac myocytes: The role of inducible nitric oxide synthase induction and peroxynitrite generation
-
Arstall MA, Sawyer DB, Fukazawa R, and Kelly RA. Cyto-kine-mediated apoptosis in cardiac myocytes: the role of inducible nitric oxide synthase induction and peroxynitrite generation. Circ Res 85: 829-840, 1999.
-
(1999)
Circ Res
, vol.85
, pp. 829-840
-
-
Arstall, M.A.1
Sawyer, D.B.2
Fukazawa, R.3
Kelly, R.A.4
-
3
-
-
77249137656
-
The EGCg-induced re-dox-sensitive activation of endothelial nitric oxide synthase and relaxation are critically dependent on hydroxyl moieties
-
Auger C, Kim JH, Chabert P, Chaabi M, Anselm E, Lanciaux X, Lobstein A, and Schini-Kerth VB. The EGCg-induced re-dox-sensitive activation of endothelial nitric oxide synthase and relaxation are critically dependent on hydroxyl moieties. Biochem Biophys Res Commun 393: 162-167, 2010.
-
(2010)
Biochem Biophys Res Commun
, vol.393
, pp. 162-167
-
-
Auger, C.1
Kim, J.H.2
Chabert, P.3
Chaabi, M.4
Anselm, E.5
Lanciaux, X.6
Lobstein, A.7
Schini-Kerth, V.B.8
-
4
-
-
0032787638
-
Myocardial protection by insulin is dependent on phospatidylinositol 3-kinase but not protein kinase C or KATP channels in the isolated rabbit heart
-
Baines CP, Wang L, Cohen MV, and Downey JM. Myocardial protection by insulin is dependent on phospatidylinositol 3-kinase but not protein kinase C or KATP channels in the isolated rabbit heart. Basic Res Cardiol 94: 188-198, 1999.
-
(1999)
Basic Res Cardiol
, vol.94
, pp. 188-198
-
-
Baines, C.P.1
Wang, L.2
Cohen, M.V.3
Downey, J.M.4
-
5
-
-
0029805172
-
Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly
-
Beckman JS and Koppenol WH. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol 271: C1424-C1437, 1996.
-
(1996)
Am J Physiol
, vol.271
-
-
Beckman, J.S.1
Koppenol, W.H.2
-
6
-
-
36849013016
-
Enhanced ryanodine receptor-mediated calcium leak determines reduced sarcoplasmic reticulum calcium content in chronic canine heart failure
-
Belevych A, Kubalova Z, Terentyev D, Hamlin RL, Carnes CA, and Gyorke S. Enhanced ryanodine receptor-mediated calcium leak determines reduced sarcoplasmic reticulum calcium content in chronic canine heart failure. Biophys J 93: 4083-4092, 2007.
-
(2007)
Biophys J
, vol.93
, pp. 4083-4092
-
-
Belevych, A.1
Kubalova, Z.2
Terentyev, D.3
Hamlin, R.L.4
Carnes, C.A.5
Gyorke, S.6
-
7
-
-
10744228523
-
Adult cardiac stem cells are multipotent and support myocardial regeneration
-
Beltrami AP, Barlucchi L, Torella D, Baker M, Limana F, Chimenti S, Kasahara H, Rota M, Musso E, Urbanek K, Leri A, Kajstura J, Nadal-Ginard B, and Anversa P. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 114: 763-776, 2003.
-
(2003)
Cell
, vol.114
, pp. 763-776
-
-
Beltrami, A.P.1
Barlucchi, L.2
Torella, D.3
Baker, M.4
Limana, F.5
Chimenti, S.6
Kasahara, H.7
Rota, M.8
Musso, E.9
Urbanek, K.10
Leri, A.11
Kajstura, J.12
Nadal-Ginard, B.13
Anversa, P.14
-
8
-
-
0035821988
-
Evidence that human cardiac myocytes divide after myocardial infarction
-
Beltrami AP, Urbanek K, Kajstura J, Yan SM, Finato N, Bussani R, Nadal-Ginard B, Silvestri F, Leri A, Beltrami CA, and Anversa P. Evidence that human cardiac myocytes divide after myocardial infarction. N Engl J Med 344: 1750-1757, 2001.
-
(2001)
N Engl J Med
, vol.344
, pp. 1750-1757
-
-
Beltrami, A.P.1
Urbanek, K.2
Kajstura, J.3
Yan, S.M.4
Finato, N.5
Bussani, R.6
Nadal-Ginard, B.7
Silvestri, F.8
Leri, A.9
Beltrami, C.A.10
Anversa, P.11
-
9
-
-
0036849331
-
PKB binding proteins, Getting in on the Akt
-
Brazil DP, Park J, and Hemmings BA. PKB binding proteins. Getting in on the Akt. Cell 111: 293-303, 2002.
-
(2002)
Cell
, vol.111
, pp. 293-303
-
-
Brazil, D.P.1
Park, J.2
Hemmings, B.A.3
-
10
-
-
0034383952
-
The MEK1-ERK1=2 signaling pathway promotes compensated cardiac hypertrophy in trans-genic mice
-
Bueno OF, De Windt LJ, Tymitz KM, Witt SA, Kimball TR, Klevitsky R, Hewett TE, Jones SP, Lefer DJ, Peng CF, Kitsis RN, and Molkentin JD. The MEK1-ERK1=2 signaling pathway promotes compensated cardiac hypertrophy in trans-genic mice. EMBO J 19: 6341-6350, 2000.
-
(2000)
EMBO J
, vol.19
, pp. 6341-6350
-
-
Bueno, O.F.1
De Windt, L.J.2
Tymitz, K.M.3
Witt, S.A.4
Kimball, T.R.5
Klevitsky, R.6
Hewett, T.E.7
Jones, S.P.8
Lefer, D.J.9
Peng, C.F.10
Kitsis, R.N.11
Molkentin, J.D.12
-
11
-
-
0029743817
-
Redox modulation of L-type calcium channels in ferret ventricular myo-cytes. Dual mechanism regulation by nitric oxide and S-nitrosothiols
-
Campbell DL, Stamler JS, and Strauss HC. Redox modulation of L-type calcium channels in ferret ventricular myo-cytes. Dual mechanism regulation by nitric oxide and S-nitrosothiols. J Gen Physiol 108: 277-293, 1996.
-
(1996)
J Gen Physiol
, vol.108
, pp. 277-293
-
-
Campbell, D.L.1
Stamler, J.S.2
Strauss, H.C.3
-
12
-
-
0037205048
-
The phosphoinositide 3-kinase pathway
-
Cantley LC. The phosphoinositide 3-kinase pathway. Science 296: 1655-1657, 2002.
-
(2002)
Science
, vol.296
, pp. 1655-1657
-
-
Cantley, L.C.1
-
13
-
-
33846315467
-
Clinical trials update from the American Heart Association 2006: OAT, SALT 1 and 2, MAGIC, ABCD, PABA-CHF, IMPROVE-CHF, and percutaneous mitral annuloplasty
-
Cleland JG, Coletta AP, Abdellah AT, Nasir M, Hobson N, Freemantle N, and Clark AL. Clinical trials update from the American Heart Association 2006: OAT, SALT 1 and 2, MAGIC, ABCD, PABA-CHF, IMPROVE-CHF, and percutaneous mitral annuloplasty. Eur J Heart Fail 9: 92-97, 2007.
-
(2007)
Eur J Heart Fail
, vol.9
, pp. 92-97
-
-
Cleland, J.G.1
Coletta, A.P.2
Abdellah, A.T.3
Nasir, M.4
Hobson, N.5
Freemantle, N.6
Clark, A.L.7
-
14
-
-
16844382827
-
Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis. Essential role of nitric oxide signaling
-
Das A, Xi L, and Kukreja RC. Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis. Essential role of nitric oxide signaling. J Biol Chem 280: 12944-12955, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 12944-12955
-
-
Das, A.1
Xi, L.2
Kukreja, R.C.3
-
15
-
-
0037028866
-
The antioxidant N-2-mercaptopropionyl glycine attenuates left ventricular hypertrophy in in vivo murine pressure-overload model
-
Date MO, Morita T, Yamashita N, Nishida K, Yamaguchi O, Higuchi Y, Hirotani S, Matsumura Y, Hori M, Tada M, and Otsu K. The antioxidant N-2-mercaptopropionyl glycine attenuates left ventricular hypertrophy in in vivo murine pressure-overload model. J Am Coll Cardiol 39: 907-912, 2002.
-
(2002)
J Am Coll Cardiol
, vol.39
, pp. 907-912
-
-
Date, M.O.1
Morita, T.2
Yamashita, N.3
Nishida, K.4
Yamaguchi, O.5
Higuchi, Y.6
Hirotani, S.7
Matsumura, Y.8
Hori, M.9
Tada, M.10
Otsu, K.11
-
16
-
-
0030221307
-
Role of oxidative stress in transition of hypertrophy to heart failure
-
Dhalla AK, Hill MF, and Singal PK. Role of oxidative stress in transition of hypertrophy to heart failure. J Am Coll Cardiol 28: 506-514, 1996.
-
(1996)
J Am Coll Cardiol
, vol.28
, pp. 506-514
-
-
Dhalla, A.K.1
Hill, M.F.2
Singal, P.K.3
-
17
-
-
0028356959
-
Antioxidant changes in hyper-trophied and failing guinea pig hearts
-
Dhalla AK and Singal PK. Antioxidant changes in hyper-trophied and failing guinea pig hearts. Am J Physiol 266: H1280-H1285, 1994.
-
(1994)
Am J Physiol
, vol.266
-
-
Dhalla, A.K.1
Singal, P.K.2
-
18
-
-
0030069613
-
Increased malondialdehyde in peripheral blood of patients with congestive heart failure
-
Diaz-Velez CR, Garcia-Castineiras S, Mendoza-Ramos E, and Hernandez-Lopez E. Increased malondialdehyde in peripheral blood of patients with congestive heart failure. Am Heart J 131: 146-152, 1996.
-
(1996)
Am Heart J
, vol.131
, pp. 146-152
-
-
Diaz-Velez, C.R.1
Garcia-Castineiras, S.2
Mendoza-Ramos, E.3
Hernandez-Lopez, E.4
-
19
-
-
20844461656
-
Allopurinol attenuates left ventricular remodeling and dysfunction after experimental myocardial infarction: A new action for an old drug?
-
Engberding N, Spiekermann S, Schaefer A, Heineke A, Wiencke A, Muller M, Fuchs M, Hilfiker-Kleiner D, Hornig B, Drexler H, and Landmesser U. Allopurinol attenuates left ventricular remodeling and dysfunction after experimental myocardial infarction: a new action for an old drug? Circulation 110: 2175-2179, 2004.
-
(2004)
Circulation
, vol.110
, pp. 2175-2179
-
-
Engberding, N.1
Spiekermann, S.2
Schaefer, A.3
Heineke, A.4
Wiencke, A.5
Muller, M.6
Fuchs, M.7
Hilfiker-Kleiner, D.8
Hornig, B.9
Drexler, H.10
Landmesser, U.11
-
20
-
-
0038757584
-
Protein kinase B activation by reactive oxygen species is independent of tyrosine kinase receptor phosphorylation and requires SRC activity
-
Esposito F, Chirico G, Montesano Gesualdi N, Posadas I, Ammendola R, Russo T, Cirino G, and Cimino F. Protein kinase B activation by reactive oxygen species is independent of tyrosine kinase receptor phosphorylation and requires SRC activity. J Biol Chem 278: 20828-20834, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 20828-20834
-
-
Esposito, F.1
Chirico, G.2
Montesano Gesualdi, N.3
Posadas, I.4
Ammendola, R.5
Russo, T.6
Cirino, G.7
Cimino, F.8
-
21
-
-
0035822692
-
Increased inducible nitric oxide synthase expression contributes to myocardial dysfunction and higher mortality after myocar-dial infarction in mice
-
Feng Q, Lu X, Jones DL, Shen J, and Arnold JM. Increased inducible nitric oxide synthase expression contributes to myocardial dysfunction and higher mortality after myocar-dial infarction in mice. Circulation 104: 700-704, 2001.
-
(2001)
Circulation
, vol.104
, pp. 700-704
-
-
Feng, Q.1
Lu, X.2
Jones, D.L.3
Shen, J.4
Arnold, J.M.5
-
22
-
-
0037072469
-
Development of heart failure and congenital septal defects in mice lacking endothelial nitric oxide synthase
-
Feng Q, Song W, Lu X, Hamilton JA, Lei M, Peng T, and Yee SP. Development of heart failure and congenital septal defects in mice lacking endothelial nitric oxide synthase. Circulation 106: 873-879, 2002.
-
(2002)
Circulation
, vol.106
, pp. 873-879
-
-
Feng, Q.1
Song, W.2
Lu, X.3
Hamilton, J.A.4
Lei, M.5
Peng, T.6
Yee, S.P.7
-
24
-
-
0034651983
-
Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart
-
Fujio Y, Nguyen T, Wencker D, Kitsis RN, and Walsh K. Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart. Circulation 101: 660-667, 2000.
-
(2000)
Circulation
, vol.101
, pp. 660-667
-
-
Fujio, Y.1
Nguyen, T.2
Wencker, D.3
Kitsis, R.N.4
Walsh, K.5
-
25
-
-
0344924865
-
Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase=Akt
-
Fukazawa R, Miller TA, Kuramochi Y, Frantz S, Kim YD, Marchionni MA, Kelly RA, and Sawyer DB. Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase=Akt. J Mol Cell Cardiol 35: 1473-1479, 2003.
-
(2003)
J Mol Cell Cardiol
, vol.35
, pp. 1473-1479
-
-
Fukazawa, R.1
Miller, T.A.2
Kuramochi, Y.3
Frantz, S.4
Kim, Y.D.5
Marchionni, M.A.6
Kelly, R.A.7
Sawyer, D.B.8
-
26
-
-
33644866801
-
Impaired angio-genesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction
-
Galasso G, Schiekofer S, Sato K, Shibata R, Handy DE, Ouchi N, Leopold JA, Loscalzo J, and Walsh K. Impaired angio-genesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction. Circ Res 98: 254-261, 2006.
-
(2006)
Circ Res
, vol.98
, pp. 254-261
-
-
Galasso, G.1
Schiekofer, S.2
Sato, K.3
Shibata, R.4
Handy, D.E.5
Ouchi, N.6
Leopold, J.A.7
Loscalzo, J.8
Walsh, K.9
-
27
-
-
0028288189
-
Transverse shape characteristics of cardiac myocytes from rats and humans
-
Gerdes AM, Kellerman SE, Malec KB, and Schocken DD. Transverse shape characteristics of cardiac myocytes from rats and humans. Cardioscience 5: 31-36, 1994.
-
(1994)
Cardioscience
, vol.5
, pp. 31-36
-
-
Gerdes, A.M.1
Kellerman, S.E.2
Malec, K.B.3
Schocken, D.D.4
-
28
-
-
22544453858
-
Intracellular reactive oxygen species activate Src tyrosine kinase during cell adhesion and anchorage-dependent cell growth
-
Giannoni E, Buricchi F, Raugei G, Ramponi G, and Chiarugi P. Intracellular reactive oxygen species activate Src tyrosine kinase during cell adhesion and anchorage-dependent cell growth. Mol Cell Biol 25: 6391-6403, 2005.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 6391-6403
-
-
Giannoni, E.1
Buricchi, F.2
Raugei, G.3
Ramponi, G.4
Chiarugi, P.5
-
29
-
-
0002906703
-
-
Heart Disease: A Textbook of Cardiovascular Medicine, edited by Braunwald E. Philadelphia: W.B. Sanders
-
Givertz MM, Colucci WS, and Braunwald E. Clinical aspects of heart failure: high-output failure; pulmonary edema. In: Heart Disease: A Textbook of Cardiovascular Medicine, edited by Braunwald E. Philadelphia: W.B. Sanders, 2001, pp. 534-561.
-
(2001)
Clinical Aspects of Heart Failure: High-output Failure; Pulmonary Edema.
, pp. 534-561
-
-
Givertz, M.M.1
Colucci, W.S.2
Braunwald, E.3
-
30
-
-
33750740174
-
2\+ exchange in ventricular myocytes
-
2\+ exchange in ventricular myocytes. Am J Physiol 271: H823-H833, 1996.
-
(1996)
Am J Physiol
, vol.271
-
-
Goldhaber, J.I.1
-
31
-
-
70349961689
-
S-Nitrosylation of cardiac ion channels
-
Gonzalez DR, Treuer A, Sun QA, Stamler JS, and Hare JM. S-Nitrosylation of cardiac ion channels. J Cardiovasc Pharmacol 54: 188-195, 2009.
-
(2009)
J Cardiovasc Pharmacol
, vol.54
, pp. 188-195
-
-
Gonzalez, D.R.1
Treuer, A.2
Sun, Q.A.3
Stamler, J.S.4
Hare, J.M.5
-
32
-
-
0029958876
-
Isolation and functional properties of murine hemato-poietic stem cells that are replicating in vivo
-
Goodell MA, Brose K, Paradis G, Conner AS, and Mulligan RC. Isolation and functional properties of murine hemato-poietic stem cells that are replicating in vivo. J Exp Med 183: 1797-1806, 1996.
-
(1996)
J Exp Med
, vol.183
, pp. 1797-1806
-
-
Goodell, M.A.1
Brose, K.2
Paradis, G.3
Conner, A.S.4
Mulligan, R.C.5
-
33
-
-
34250162828
-
Ischemia-reperfusion and cardioprotection: A delicate balance between reactive oxygen species generation and redox homeostasis
-
Goswami SK, Maulik N, and Das DK. Ischemia-reperfusion and cardioprotection: a delicate balance between reactive oxygen species generation and redox homeostasis. Ann Med 39: 275-289, 2007.
-
(2007)
Ann Med
, vol.39
, pp. 275-289
-
-
Goswami, S.K.1
Maulik, N.2
Das, D.K.3
-
34
-
-
73449129394
-
Hydrogen peroxide as a cell-survival signaling molecule
-
Groeger G, Quiney C, and Cotter TG. Hydrogen peroxide as a cell-survival signaling molecule. Antioxid Redox Signal 11: 2655-2671, 2009.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 2655-2671
-
-
Groeger, G.1
Quiney, C.2
Cotter, T.G.3
-
35
-
-
38849156952
-
Heart mitochondria: Gates of life and death
-
Gustafsson AB and Gottlieb RA. Heart mitochondria: gates of life and death. Cardiovasc Res 77: 334-343, 2008.
-
(2008)
Cardiovasc Res
, vol.77
, pp. 334-343
-
-
Gustafsson, A.B.1
Gottlieb, R.A.2
-
36
-
-
0030049439
-
Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury
-
Guyton KZ, Liu Y, Gorospe M, Xu Q, and Holbrook NJ. Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury. J Biol Chem 271: 4138-4142, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 4138-4142
-
-
Guyton, K.Z.1
Liu, Y.2
Gorospe, M.3
Xu, Q.4
Holbrook, N.J.5
-
37
-
-
0022394280
-
The importance of free radicals and catalytic metal ions in human diseases
-
Halliwell B and Gutteridge JM. The importance of free radicals and catalytic metal ions in human diseases. Mol Aspects Med 8: 89-193, 1985.
-
(1985)
Mol Aspects Med
, vol.8
, pp. 89-193
-
-
Halliwell, B.1
Gutteridge, J.M.2
-
38
-
-
0037785375
-
Nitric oxide and excitation-contraction coupling
-
Hare JM. Nitric oxide and excitation-contraction coupling. J Mol Cell Cardiol 35: 719-729, 2003.
-
(2003)
J Mol Cell Cardiol
, vol.35
, pp. 719-729
-
-
Hare, J.M.1
-
39
-
-
44649122196
-
Impact of oxypurinol in patients with symptomatic heart failure. Results of the OPT-CHF study
-
Hare JM, Mangal B, Brown J, Fisher C, Jr., Freudenberger R, Colucci WS, Mann DL, Liu P, Givertz MM, and Schwarz RP. Impact of oxypurinol in patients with symptomatic heart failure. Results of the OPT-CHF study. J Am Coll Cardiol 51: 2301-2309, 2008.
-
(2008)
J Am Coll Cardiol
, vol.51
, pp. 2301-2309
-
-
Hare, J.M.1
Mangal, B.2
Brown, J.3
Fisher Jr., C.4
Freudenberger, R.5
Colucci, W.S.6
Mann, D.L.7
Liu, P.8
Givertz, M.M.9
Schwarz, R.P.10
-
40
-
-
0345157579
-
Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease
-
Hennekens CH, Buring JE, Manson JE, Stampfer M, Rosner B, Cook NR, Belanger C, LaMotte F, Gaziano JM, Ridker PM, Willett W, and Peto R. Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med 334: 1145-1149, 1996.
-
(1996)
N Engl J Med
, vol.334
, pp. 1145-1149
-
-
Hennekens, C.H.1
Buring, J.E.2
Manson, J.E.3
Stampfer, M.4
Rosner, B.5
Cook, N.R.6
Belanger, C.7
Lamotte, F.8
Gaziano, J.M.9
Ridker, P.M.10
Willett, W.11
Peto, R.12
-
41
-
-
0037163903
-
The post-natal heart contains a myocardial stem cell population
-
Hierlihy AM, Seale P, Lobe CG, Rudnicki MA, and Megeney LA. The post-natal heart contains a myocardial stem cell population. FEBS Lett 530: 239-243, 2002.
-
(2002)
FEBS Lett
, vol.530
, pp. 239-243
-
-
Hierlihy, A.M.1
Seale, P.2
Lobe, C.G.3
Rudnicki, M.A.4
Megeney, L.A.5
-
42
-
-
0030030304
-
Antioxidant and oxidative stress changes during heart failure subsequent to myocardial infarction in rats
-
Hill MF and Singal PK. Antioxidant and oxidative stress changes during heart failure subsequent to myocardial infarction in rats. Am J Pathol 148: 291-300, 1996.
-
(1996)
Am J Pathol
, vol.148
, pp. 291-300
-
-
Hill, M.F.1
Singal, P.K.2
-
43
-
-
14444281569
-
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK=JNK and p38 signaling pathways
-
Ichijo H, Nishida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T, Takagi M, Matsumoto K, Miyazono K, and Gotoh Y. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK=JNK and p38 signaling pathways. Science 275: 90-94, 1997.
-
(1997)
Science
, vol.275
, pp. 90-94
-
-
Ichijo, H.1
Nishida, E.2
Irie, K.3
Ten Dijke, P.4
Saitoh, M.5
Moriguchi, T.6
Takagi, M.7
Matsumoto, K.8
Miyazono, K.9
Gotoh, Y.10
-
44
-
-
0033593596
-
Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide
-
Ing DJ, Zang J, Dzau VJ, Webster KA, and Bishopric NH. Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide, Bak, and Bcl-x. Circ Res 84: 21-33, 1999.
-
(1999)
Bak, and Bcl-x. Circ Res
, vol.84
, pp. 21-33
-
-
Ing, D.J.1
Zang, J.2
Dzau, V.J.3
Webster, K.A.4
Bishopric, N.H.5
-
45
-
-
85047692700
-
Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mito-chondrial permeability transition pore
-
Juhaszova M, Zorov DB, Kim SH, Pepe S, Fu Q, Fishbein KW, Ziman BD, Wang S, Ytrehus K, Antos CL, Olson EN, and Sollott SJ. Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mito-chondrial permeability transition pore. J Clin Invest 113: 1535-1549, 2004.
-
(2004)
J Clin Invest
, vol.113
, pp. 1535-1549
-
-
Juhaszova, M.1
Zorov, D.B.2
Kim, S.H.3
Pepe, S.4
Fu, Q.5
Fishbein, K.W.6
Ziman, B.D.7
Wang, S.8
Ytrehus, K.9
Antos, C.L.10
Olson, E.N.11
Sollott, S.J.12
-
46
-
-
33947680221
-
The telomere-telomerase axis and the heart
-
Kajstura J, Rota M, Urbanek K, Hosoda T, Bearzi C, Anversa P, Bolli R, and Leri A. The telomere-telomerase axis and the heart. Antioxid Redox Signal 8: 2125-2141, 2006.
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 2125-2141
-
-
Kajstura, J.1
Rota, M.2
Urbanek, K.3
Hosoda, T.4
Bearzi, C.5
Anversa, P.6
Bolli, R.7
Leri, A.8
-
47
-
-
0032080550
-
Increased oxidative stress in patients with congestive heart failure
-
Keith M, Geranmayegan A, Sole MJ, Kurian R, Robinson A, Omran AS, and Jeejeebhoy KN. Increased oxidative stress in patients with congestive heart failure. J Am Coll Cardiol 31: 1352-1356, 1998.
-
(1998)
J Am Coll Cardiol
, vol.31
, pp. 1352-1356
-
-
Keith, M.1
Geranmayegan, A.2
Sole, M.J.3
Kurian, R.4
Robinson, A.5
Omran, A.S.6
Jeejeebhoy, K.N.7
-
48
-
-
0038165407
-
Nitric oxide regulation of myocardial contractility and calcium cycling: Independent impact of neuronal and en-dothelial nitric oxide synthases
-
Khan SA, Skaf MW, Harrison RW, Lee K, Minhas KM, Kumar A, Fradley M, Shoukas AA, Berkowitz DE, and Hare JM. Nitric oxide regulation of myocardial contractility and calcium cycling: independent impact of neuronal and en-dothelial nitric oxide synthases. Circ Res 92: 1322-1329, 2003.
-
(2003)
Circ Res
, vol.92
, pp. 1322-1329
-
-
Khan, S.A.1
Skaf, M.W.2
Harrison, R.W.3
Lee, K.4
Minhas, K.M.5
Kumar, A.6
Fradley, M.7
Shoukas, A.A.8
Berkowitz, D.E.9
Hare, J.M.10
-
49
-
-
0034283407
-
Treatment with di-methylthiourea prevents left ventricular remodeling and failure after experimental myocardial infarction in mice: Role of oxidative stress
-
Kinugawa S, Tsutsui H, Hayashidani S, Ide T, Suematsu N, Satoh S, Utsumi H, and Takeshita A. Treatment with di-methylthiourea prevents left ventricular remodeling and failure after experimental myocardial infarction in mice: role of oxidative stress. Circ Res 87: 392-398, 2000.
-
(2000)
Circ Res
, vol.87
, pp. 392-398
-
-
Kinugawa, S.1
Tsutsui, H.2
Hayashidani, S.3
Ide, T.4
Suematsu, N.5
Satoh, S.6
Utsumi, H.7
Takeshita, A.8
-
50
-
-
0031034574
-
Antiapoptotic signalling by the insulin-like growth factor i receptor, phosphatidyli-nositol 3-kinase, and Akt
-
Kulik G, Klippel A, and Weber MJ. Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidyli-nositol 3-kinase, and Akt. Mol Cell Biol 17: 1595-1606, 1997.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 1595-1606
-
-
Kulik, G.1
Klippel, A.2
Weber, M.J.3
-
51
-
-
13444283520
-
Mineralocorticoid receptor inhibition ameliorates the transition to myocardial failure and decreases oxidative stress and inflammation in mice with chronic pressure overload
-
Kuster GM, Kotlyar E, Rude MK, Siwik DA, Liao R, Colucci WS, and Sam F. Mineralocorticoid receptor inhibition ameliorates the transition to myocardial failure and decreases oxidative stress and inflammation in mice with chronic pressure overload. Circulation 111: 420-427, 2005.
-
(2005)
Circulation
, vol.111
, pp. 420-427
-
-
Kuster, G.M.1
Kotlyar, E.2
Rude, M.K.3
Siwik, D.A.4
Liao, R.5
Colucci, W.S.6
Sam, F.7
-
52
-
-
77950340945
-
2\+ depletion in cardiac myocytes
-
2\+ depletion in cardiac myocytes. Free Radic Biol Med 48: 1182-1187, 2010.
-
(2010)
Free Radic Biol Med
, vol.48
, pp. 1182-1187
-
-
Kuster, G.M.1
Lancel, S.2
Zhang, J.3
Communal, C.4
Trucillo, M.P.5
Lim, C.C.6
Pfister, O.7
Weinberg, E.O.8
Cohen, R.A.9
Liao, R.10
Siwik, D.A.11
Colucci, W.S.12
-
53
-
-
77952586057
-
Role of RAS inhibition in the regulation of Cu=Zn-SOD in the cardiac and peripheral arterial beds in humans
-
Kuster GM, Nietlispach F, Kiowski W, Schindler R, Bern-heim A, Schuetz P, Mueller B, Morgenthaler NG, Ruter F, Riesen W, Rickli H, and Brunner-La Rocca HP. Role of RAS inhibition in the regulation of Cu=Zn-SOD in the cardiac and peripheral arterial beds in humans. Clin Pharmacol Ther 87: 686-692, 2010.
-
(2010)
Clin Pharmacol Ther
, vol.87
, pp. 686-692
-
-
Kuster, G.M.1
Nietlispach, F.2
Kiowski, W.3
Schindler, R.4
Bern-Heim, A.5
Schuetz, P.6
Mueller, B.7
Morgenthaler, N.G.8
Ruter, F.9
Riesen, W.10
Rickli, H.11
Brunner-La Rocca, H.P.12
-
54
-
-
14944371448
-
Alpha-ad-renergic receptor-stimulated hypertrophy in adult rat ventricular myocytes is mediated via thioredoxin-1-sensitive oxidative modification of thiols on Ras
-
Kuster GM, Pimentel DR, Adachi T, Ido Y, Brenner DA, Cohen RA, Liao R, Siwik DA, and Colucci WS. Alpha-ad-renergic receptor-stimulated hypertrophy in adult rat ventricular myocytes is mediated via thioredoxin-1-sensitive oxidative modification of thiols on Ras. Circulation 111: 1192-1198, 2005.
-
(2005)
Circulation
, vol.111
, pp. 1192-1198
-
-
Kuster, G.M.1
Pimentel, D.R.2
Adachi, T.3
Ido, Y.4
Brenner, D.A.5
Cohen, R.A.6
Liao, R.7
Siwik, D.A.8
Colucci, W.S.9
-
55
-
-
0037905740
-
H(2)O(2)regulates cardiac myocyte phenotype via concentration-dependent activation of distinct kinase pathways
-
Kwon SH, Pimentel DR, Remondino A, Sawyer DB, and Colucci WS. H(2)O(2) regulates cardiac myocyte phenotype via concentration-dependent activation of distinct kinase pathways. J Mol Cell Cardiol 35: 615-621, 2003.
-
(2003)
J Mol Cell Cardiol
, vol.35
, pp. 615-621
-
-
Kwon, S.H.1
Pimentel, D.R.2
Remondino, A.3
Sawyer, D.B.4
Colucci, W.S.5
-
56
-
-
64249168937
-
Nitroxyl activates SERCA in cardiac myocytes via glutathiolation of cysteine 674
-
Lancel S, Zhang J, Evangelista A, Trucillo MP, Tong X, Siwik DA, Cohen RA, and Colucci WS. Nitroxyl activates SERCA in cardiac myocytes via glutathiolation of cysteine 674. Circ Res 104: 720-723, 2009.
-
(2009)
Circ Res
, vol.104
, pp. 720-723
-
-
Lancel, S.1
Zhang, J.2
Evangelista, A.3
Trucillo, M.P.4
Tong, X.5
Siwik, D.A.6
Cohen, R.A.7
Colucci, W.S.8
-
57
-
-
3242832595
-
Redox regulation of cell signalling
-
Lander HM, Milbank AJ, Tauras JM, Hajjar DP, Hempstead BL, Schwartz GD, Kraemer RT, Mirza UA, Chait BT, Burk SC, and Quilliam LA. Redox regulation of cell signalling. Nature 381: 380-381, 1996.
-
(1996)
Nature
, vol.381
, pp. 380-381
-
-
Lander, H.M.1
Milbank, A.J.2
Tauras, J.M.3
Hajjar, D.P.4
Hempstead, B.L.5
Schwartz, G.D.6
Kraemer, R.T.7
Mirza, U.A.8
Chait, B.T.9
Burk, S.C.10
Quilliam, L.A.11
-
58
-
-
0142137134
-
Redox regulation of PI 3-kinase signalling via inactivation of PTEN
-
Leslie NR, Bennett D, Lindsay YE, Stewart H, Gray A, and Downes CP. Redox regulation of PI 3-kinase signalling via inactivation of PTEN. EMBO J 22: 5501-5510, 2003.
-
(2003)
EMBO J
, vol.22
, pp. 5501-5510
-
-
Leslie, N.R.1
Bennett, D.2
Lindsay, Y.E.3
Stewart, H.4
Gray, A.5
Downes, C.P.6
-
59
-
-
0033553389
-
Insulin-like growth factor-1 attenuates the detrimental impact of nonocclusive coronary artery constriction on the heart
-
Li B, Setoguchi M, Wang X, Andreoli AM, Leri A, Malhotra A, Kajstura J, and Anversa P. Insulin-like growth factor-1 attenuates the detrimental impact of nonocclusive coronary artery constriction on the heart. Circ Res 84: 1007-1019, 1999.
-
(1999)
Circ Res
, vol.84
, pp. 1007-1019
-
-
Li, B.1
Setoguchi, M.2
Wang, X.3
Andreoli, A.M.4
Leri, A.5
Malhotra, A.6
Kajstura, J.7
Anversa, P.8
-
60
-
-
20044383911
-
Effects of long-term vitamin e supplementation on cardiovascular events and cancer: A randomized controlled trial
-
Lonn E, Bosch J, Yusuf S, Sheridan P, Pogue J, Arnold JM, Ross C, Arnold A, Sleight P, Probstfield J, and Dagenais GR. Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial. JAMA 293: 1338-1347, 2005.
-
(2005)
JAMA
, vol.293
, pp. 1338-1347
-
-
Lonn, E.1
Bosch, J.2
Yusuf, S.3
Sheridan, P.4
Pogue, J.5
Arnold, J.M.6
Ross, C.7
Arnold, A.8
Sleight, P.9
Probstfield, J.10
Dagenais, G.R.11
-
61
-
-
0030685743
-
Changes in gene expression in the intact human heart. Downregulation of alpha-myosin heavy chain in hy-pertrophied, failing ventricular myocardium
-
Lowes BD, Minobe W, Abraham WT, Rizeq MN, Bohlmeyer TJ, Quaife RA, Roden RL, Dutcher DL, Robertson AD, Voelkel NF, Badesch DB, Groves BM, Gilbert EM, and Bristow MR. Changes in gene expression in the intact human heart. Downregulation of alpha-myosin heavy chain in hy-pertrophied, failing ventricular myocardium. J Clin Invest 100: 2315-2324, 1997.
-
(1997)
J Clin Invest
, vol.100
, pp. 2315-2324
-
-
Lowes, B.D.1
Minobe, W.2
Abraham, W.T.3
Rizeq, M.N.4
Bohlmeyer, T.J.5
Quaife, R.A.6
Roden, R.L.7
Dutcher, D.L.8
Robertson, A.D.9
Voelkel, N.F.10
Badesch, D.B.11
Groves, B.M.12
Gilbert, E.M.13
Bristow, M.R.14
-
62
-
-
0343307138
-
Death by design. Programmed cell death in cardiovascular biology and disease
-
MacLellan WR and Schneider MD. Death by design. Programmed cell death in cardiovascular biology and disease. Circ Res 81: 137-144, 1997.
-
(1997)
Circ Res
, vol.81
, pp. 137-144
-
-
MacLellan, W.R.1
Schneider, M.D.2
-
63
-
-
0032574631
-
Elevated levels of 8-iso-prostaglandin F2alpha in pericardial fluid of patients with heart failure: A potential role for in vivo oxidant stress in ventricular dilatation and progression to heart failure
-
Mallat Z, Philip I, Lebret M, Chatel D, Maclouf J, and Tedgui A. Elevated levels of 8-iso-prostaglandin F2alpha in pericardial fluid of patients with heart failure: a potential role for in vivo oxidant stress in ventricular dilatation and progression to heart failure. Circulation 97: 1536-1539, 1998.
-
(1998)
Circulation
, vol.97
, pp. 1536-1539
-
-
Mallat, Z.1
Philip, I.2
Lebret, M.3
Chatel, D.4
MacLouf, J.5
Tedgui, A.6
-
64
-
-
33644874959
-
Mitochondrial dysfunction and apoptosis underlie the pathogenic process in alpha-B-crystallin desmin-related cardiomyopathy
-
Maloyan A, Sanbe A, Osinska H, Westfall M, Robinson D, Imahashi K, Murphy E, and Robbins J. Mitochondrial dysfunction and apoptosis underlie the pathogenic process in alpha-B-crystallin desmin-related cardiomyopathy. Circulation 112: 3451-3461, 2005.
-
(2005)
Circulation
, vol.112
, pp. 3451-3461
-
-
Maloyan, A.1
Sanbe, A.2
Osinska, H.3
Westfall, M.4
Robinson, D.5
Imahashi, K.6
Murphy, E.7
Robbins, J.8
-
65
-
-
43449137865
-
Hypoxia-inducible factor-2alpha transactivates Abcg2 and promotes cytoprotection in cardiac side population cells
-
Martin CM, Ferdous A, Gallardo T, Humphries C, Sadek H, Caprioli A, Garcia JA, Szweda LI, Garry MG, and Garry DJ. Hypoxia-inducible factor-2alpha transactivates Abcg2 and promotes cytoprotection in cardiac side population cells. Circ Res 102: 1075-1081, 2008.
-
(2008)
Circ Res
, vol.102
, pp. 1075-1081
-
-
Martin, C.M.1
Ferdous, A.2
Gallardo, T.3
Humphries, C.4
Sadek, H.5
Caprioli, A.6
Garcia, J.A.7
Szweda, L.I.8
Garry, M.G.9
Garry, D.J.10
-
66
-
-
0033534088
-
Adenoviral gene transfer of activated phosphatidylinositol 3'-kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro
-
Matsui T, Li L, del Monte F, Fukui Y, Franke TF, Hajjar RJ, and Rosenzweig A. Adenoviral gene transfer of activated phosphatidylinositol 3'-kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro. Circulation 100: 2373-2379, 1999.
-
(1999)
Circulation
, vol.100
, pp. 2373-2379
-
-
Matsui, T.1
Li, L.2
Del Monte, F.3
Fukui, Y.4
Franke, T.F.5
Hajjar, R.J.6
Rosenzweig, A.7
-
67
-
-
0035902451
-
Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo
-
Matsui T, Tao J, del Monte F, Lee KH, Li L, Picard M, Force TL, Franke TF, Hajjar RJ, and Rosenzweig A. Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo. Circulation 104: 330-335, 2001.
-
(2001)
Circulation
, vol.104
, pp. 330-335
-
-
Matsui, T.1
Tao, J.2
Del Monte, F.3
Lee, K.H.4
Li, L.5
Picard, M.6
Force, T.L.7
Franke, T.F.8
Hajjar, R.J.9
Rosenzweig, A.10
-
68
-
-
14044265068
-
Stress-responsive protein ki-nases in redox-regulated apoptosis signaling
-
Matsuzawa A and Ichijo H. Stress-responsive protein ki-nases in redox-regulated apoptosis signaling. Antioxid Redox Signal 7: 472-481, 2005.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 472-481
-
-
Matsuzawa, A.1
Ichijo, H.2
-
69
-
-
70350705973
-
Functional characterization of cardiac progenitor cells and their derivatives in the embryonic heart post-chamber formation
-
McMullen NM, Zhang F, Hotchkiss A, Bretzner F, Wilson JM, Ma H, Wafa K, Brownstone RM, and Pasumarthi KB. Functional characterization of cardiac progenitor cells and their derivatives in the embryonic heart post-chamber formation. Dev Dyn 238: 2787-2799, 2009.
-
(2009)
Dev Dyn
, vol.238
, pp. 2787-2799
-
-
McMullen, N.M.1
Zhang, F.2
Hotchkiss, A.3
Bretzner, F.4
Wilson, J.M.5
Ma, H.6
Wafa, K.7
Brownstone, R.M.8
Pasumarthi, K.B.9
-
70
-
-
33847413222
-
Glycogen synthase kinase-3beta plays a pro-apoptotic role in beta-adrenergic receptor-stimulated apoptosis in adult rat ventricular myocytes: Role of beta1 integrins
-
Menon B, Johnson JN, Ross RS, Singh M, and Singh K. Glycogen synthase kinase-3beta plays a pro-apoptotic role in beta-adrenergic receptor-stimulated apoptosis in adult rat ventricular myocytes: role of beta1 integrins. J Mol Cell Cardiol 42: 653-661, 2007.
-
(2007)
J Mol Cell Cardiol
, vol.42
, pp. 653-661
-
-
Menon, B.1
Johnson, J.N.2
Ross, R.S.3
Singh, M.4
Singh, K.5
-
71
-
-
7244261795
-
Isolation and expansion of adult cardiac stem cells from human and murine heart
-
Messina E, De Angelis L, Frati G, Morrone S, Chimenti S, Fiordaliso F, Salio M, Battaglia M, Latronico MV, Coletta M, Vivarelli E, Frati L, Cossu G, and Giacomello A. Isolation and expansion of adult cardiac stem cells from human and murine heart. Circ Res 95: 911-921, 2004.
-
(2004)
Circ Res
, vol.95
, pp. 911-921
-
-
Messina, E.1
De Angelis, L.2
Frati, G.3
Morrone, S.4
Chimenti, S.5
Fiordaliso, F.6
Salio, M.7
Battaglia, M.8
Latronico, M.V.9
Coletta, M.10
Vivarelli, E.11
Frati, L.12
Cossu, G.13
Giacomello, A.14
-
72
-
-
33644630969
-
Xanthine oxidoreductase inhibition causes reverse remodeling in rats with dilated cardiomyopathy
-
Minhas KM, Saraiva RM, Schuleri KH, Lehrke S, Zheng M, Saliaris AP, Berry CE, Barouch LA, Vandegaer KM, Li D, and Hare JM. Xanthine oxidoreductase inhibition causes reverse remodeling in rats with dilated cardiomyopathy. Circ Res 98: 271-279, 2006.
-
(2006)
Circ Res
, vol.98
, pp. 271-279
-
-
Minhas, K.M.1
Saraiva, R.M.2
Schuleri, K.H.3
Lehrke, S.4
Zheng, M.5
Saliaris, A.P.6
Berry, C.E.7
Barouch, L.A.8
Vandegaer, K.M.9
Li, D.10
Hare, J.M.11
-
73
-
-
33144479211
-
Restoration of cardiac progenitor cells after myocardial infarction by self-proliferation and selective homing of bone marrow-derived stem cells
-
Mouquet F, Pfister O, Jain M, Oikonomopoulos A, Ngoy S, Summer R, Fine A, and Liao R. Restoration of cardiac progenitor cells after myocardial infarction by self-proliferation and selective homing of bone marrow-derived stem cells. Circ Res 97: 1090-1092, 2005.
-
(2005)
Circ Res
, vol.97
, pp. 1090-1092
-
-
Mouquet, F.1
Pfister, O.2
Jain, M.3
Oikonomopoulos, A.4
Ngoy, S.5
Summer, R.6
Fine, A.7
Liao, R.8
-
74
-
-
0033952999
-
Inducible NO synthase activity in blood vessels and heart: New insight into cell origin and consequences
-
Muller B, Kleschyov AL, Gyorgy K, and Stoclet JC. Inducible NO synthase activity in blood vessels and heart: new insight into cell origin and consequences. Physiol Res 49: 19-26, 2000.
-
(2000)
Physiol Res
, vol.49
, pp. 19-26
-
-
Muller, B.1
Kleschyov, A.L.2
Gyorgy, K.3
Stoclet, J.C.4
-
75
-
-
0034681226
-
Gbetagamma-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy
-
Naga Prasad SV, Esposito G, Mao L, Koch WJ, and Rockman HA. Gbetagamma-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy. J Biol Chem 275: 4693-4698, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 4693-4698
-
-
Naga Prasad, S.V.1
Esposito, G.2
Mao, L.3
Koch, W.J.4
Rockman, H.A.5
-
76
-
-
0032566405
-
Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-alpha and angiotensin II
-
Nakamura K, Fushimi K, Kouchi H, Mihara K, Miyazaki M, Ohe T, and Namba M. Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-alpha and angiotensin II. Circulation 98: 794-799, 1998.
-
(1998)
Circulation
, vol.98
, pp. 794-799
-
-
Nakamura, K.1
Fushimi, K.2
Kouchi, H.3
Mihara, K.4
Miyazaki, M.5
Ohe, T.6
Namba, M.7
-
77
-
-
28844498707
-
Redox regulation of precursor cell function: Insights and paradoxes
-
Noble M, Mayer-Proschel M, and Proschel C. Redox regulation of precursor cell function: insights and paradoxes. Antioxid Redox Signal 7: 1456-1467, 2005.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 1456-1467
-
-
Noble, M.1
Mayer-Proschel, M.2
Proschel, C.3
-
78
-
-
0032540252
-
Activation of phosphatidyli-nositol 3-kinase through glycoprotein 130 induces protein kinase B and p70 S6 kinase phosphorylation in cardiac myocytes
-
Oh H, Fujio Y, Kunisada K, Hirota H, Matsui H, Kishimoto T, and Yamauchi-Takihara K. Activation of phosphatidyli-nositol 3-kinase through glycoprotein 130 induces protein kinase B and p70 S6 kinase phosphorylation in cardiac myocytes. J Biol Chem 273: 9703-9710, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 9703-9710
-
-
Oh, H.1
Fujio, Y.2
Kunisada, K.3
Hirota, H.4
Matsui, H.5
Kishimoto, T.6
Yamauchi-Takihara, K.7
-
79
-
-
43449116367
-
Pump to survive: Novel cytoprotective strategies for cardiac progenitor cells
-
Pfister O and Liao R. Pump to survive: novel cytoprotective strategies for cardiac progenitor cells. Circ Res 102: 998-1001, 2008.
-
(2008)
Circ Res
, vol.102
, pp. 998-1001
-
-
Pfister, O.1
Liao, R.2
-
80
-
-
22144476853
-
CD31\-but Not CD31+ cardiac side population cells exhibit functional cardiomyogenic differentiation
-
Pfister O, Mouquet F, Jain M, Summer R, Helmes M, Fine A, Colucci WS, and Liao R. CD31\-but Not CD31+ cardiac side population cells exhibit functional cardiomyogenic differentiation. Circ Res 97: 52-61, 2005.
-
(2005)
Circ Res
, vol.97
, pp. 52-61
-
-
Pfister, O.1
Mouquet, F.2
Jain, M.3
Summer, R.4
Helmes, M.5
Fine, A.6
Colucci, W.S.7
Liao, R.8
-
81
-
-
54449087399
-
Role of the ATP-binding cassette transporter Abcg2 in the phenotype and function of cardiac side population cells
-
Pfister O, Oikonomopoulos A, Sereti KI, Sohn RL, Cullen D, Fine GC, Mouquet F, Westerman K, and Liao R. Role of the ATP-binding cassette transporter Abcg2 in the phenotype and function of cardiac side population cells. Circ Res 103: 825-835, 2008.
-
(2008)
Circ Res
, vol.103
, pp. 825-835
-
-
Pfister, O.1
Oikonomopoulos, A.2
Sereti, K.I.3
Sohn, R.L.4
Cullen, D.5
Fine, G.C.6
Mouquet, F.7
Westerman, K.8
Liao, R.9
-
82
-
-
33846130574
-
Bone-marrow derived hematopoietic stem/progenitor cells express multiple isoforms of NADPH oxidase and produce constitutively reactive oxygen species
-
Piccoli C, D'Aprile A, Ripoli M, Scrima R, Lecce L, Boffoli D, Tabilio A, and Capitanio N. Bone-marrow derived hematopoietic stem/progenitor cells express multiple isoforms of NADPH oxidase and produce constitutively reactive oxygen species. Biochem Biophys Res Commun 353: 965-972, 2007.
-
(2007)
Biochem Biophys Res Commun
, vol.353
, pp. 965-972
-
-
Piccoli, C.1
D'Aprile, A.2
Ripoli, M.3
Scrima, R.4
Lecce, L.5
Boffoli, D.6
Tabilio, A.7
Capitanio, N.8
-
83
-
-
33748526792
-
Strain-stimulated hypertrophy in cardiac myocytes is mediated by reactive oxygen species-dependent Ras S-glutathiolation
-
Pimentel DR, Adachi T, Ido Y, Heibeck T, Jiang B, Lee Y, Melendez JA, Cohen RA, and Colucci WS. Strain-stimulated hypertrophy in cardiac myocytes is mediated by reactive oxygen species-dependent Ras S-glutathiolation. J Mol Cell Cardiol 41: 613-622, 2006.
-
(2006)
J Mol Cell Cardiol
, vol.41
, pp. 613-622
-
-
Pimentel, D.R.1
Adachi, T.2
Ido, Y.3
Heibeck, T.4
Jiang, B.5
Lee, Y.6
Melendez, J.A.7
Cohen, R.A.8
Colucci, W.S.9
-
84
-
-
0032887709
-
Nitric oxide triggers programmed cell death (apoptosis) of adult rat ventricular myocytes in culture
-
Pinsky DJ, Aji W, Szabolcs M, Athan ES, Liu Y, Yang YM, Kline RP, Olson KE, and Cannon PJ. Nitric oxide triggers programmed cell death (apoptosis) of adult rat ventricular myocytes in culture. Am J Physiol 277: H1189-H1199, 1999.
-
(1999)
Am J Physiol
, vol.277
-
-
Pinsky, D.J.1
Aji, W.2
Szabolcs, M.3
Athan, E.S.4
Liu, Y.5
Yang, Y.M.6
Kline, R.P.7
Olson, K.E.8
Cannon, P.J.9
-
85
-
-
0038446797
-
A dual role of the GTPase Rac in cardiac differentiation of stem cells
-
Puceat M, Travo P, Quinn MT, and Fort P. A dual role of the GTPase Rac in cardiac differentiation of stem cells. Mol Biol Cell 14: 2781-2792, 2003.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 2781-2792
-
-
Puceat, M.1
Travo, P.2
Quinn, M.T.3
Fort, P.4
-
86
-
-
34547681313
-
Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice
-
Rajasekaran NS, Connell P, Christians ES, Yan LJ, Taylor RP, Orosz A, Zhang XQ, Stevenson TJ, Peshock RM, Leopold JA, Barry WH, Loscalzo J, Odelberg SJ, and Benjamin IJ. Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice. Cell 130: 427-439, 2007.
-
(2007)
Cell
, vol.130
, pp. 427-439
-
-
Rajasekaran, N.S.1
Connell, P.2
Christians, E.S.3
Yan, L.J.4
Taylor, R.P.5
Orosz, A.6
Zhang, X.Q.7
Stevenson, T.J.8
Peshock, R.M.9
Leopold, J.A.10
Barry, W.H.11
Loscalzo, J.12
Odelberg, S.J.13
Benjamin, I.J.14
-
87
-
-
0030916162
-
Randomised trial of alpha-tocopherol and beta-carotene supplements on incidence of major coronary events in men with previous myocardial infarction
-
Rapola JM, Virtamo J, Ripatti S, Huttunen JK, Albanes D, Taylor PR, and Heinonen OP. Randomised trial of alpha-tocopherol and beta-carotene supplements on incidence of major coronary events in men with previous myocardial infarction. Lancet 349: 1715-1720, 1997.
-
(1997)
Lancet
, vol.349
, pp. 1715-1720
-
-
Rapola, J.M.1
Virtamo, J.2
Ripatti, S.3
Huttunen, J.K.4
Albanes, D.5
Taylor, P.R.6
Heinonen, O.P.7
-
88
-
-
18144387916
-
Modulation of apoptosis by nitric oxide: Implications in myocardial ischemia and heart failure
-
Razavi HM, Hamilton JA, and Feng Q. Modulation of apoptosis by nitric oxide: implications in myocardial ischemia and heart failure. Pharmacol Ther 106: 147-162, 2005.
-
(2005)
Pharmacol Ther
, vol.106
, pp. 147-162
-
-
Razavi, H.M.1
Hamilton, J.A.2
Feng, Q.3
-
89
-
-
0023031882
-
Redox modification of sodium-calcium exchange activity in cardiac sarcolemmal vesicles
-
Reeves JP, Bailey CA, and Hale CC. Redox modification of sodium-calcium exchange activity in cardiac sarcolemmal vesicles. J Biol Chem 261: 4948-4955, 1986.
-
(1986)
J Biol Chem
, vol.261
, pp. 4948-4955
-
-
Reeves, J.P.1
Bailey, C.A.2
Hale, C.C.3
-
90
-
-
0037423550
-
Beta-adrenergic receptor-stimulated apoptosis in cardiac myocytes is mediated by reactive oxygen species=c-Jun NH2-terminal kinase-dependent activation of the mitochondrial pathway
-
Remondino A, Kwon SH, Communal C, Pimentel DR, Sawyer DB, Singh K, and Colucci WS. Beta-adrenergic receptor-stimulated apoptosis in cardiac myocytes is mediated by reactive oxygen species=c-Jun NH2-terminal kinase-dependent activation of the mitochondrial pathway. Circ Res 92: 136-138, 2003.
-
(2003)
Circ Res
, vol.92
, pp. 136-138
-
-
Remondino, A.1
Kwon, S.H.2
Communal, C.3
Pimentel, D.R.4
Sawyer, D.B.5
Singh, K.6
Colucci, W.S.7
-
91
-
-
33746207801
-
Diabetes promotes cardiac stem cell aging and heart failure, which are prevented by deletion of the p66shc gene
-
Rota M, LeCapitaine N, Hosoda T, Boni A, De Angelis A, Padin-Iruegas ME, Esposito G, Vitale S, Urbanek K, Casarsa C, Giorgio M, Luscher TF, Pelicci PG, Anversa P, Leri A, and Kajstura J. Diabetes promotes cardiac stem cell aging and heart failure, which are prevented by deletion of the p66shc gene. Circ Res 99: 42-52, 2006.
-
(2006)
Circ Res
, vol.99
, pp. 42-52
-
-
Rota, M.1
Lecapitaine, N.2
Hosoda, T.3
Boni, A.4
De Angelis, A.5
Padin-Iruegas, M.E.6
Esposito, G.7
Vitale, S.8
Urbanek, K.9
Casarsa, C.10
Giorgio, M.11
Luscher, T.F.12
Pelicci, P.G.13
Anversa, P.14
Leri, A.15
Kajstura, J.16
-
92
-
-
0345258510
-
Regulation of hy-pertrophic and apoptotic signaling pathways by reactive oxygen species in cardiac myocytes
-
Sabri A, Hughie HH, and Lucchesi PA. Regulation of hy-pertrophic and apoptotic signaling pathways by reactive oxygen species in cardiac myocytes. Antioxid Redox Signal 5: 731-740, 2003.
-
(2003)
Antioxid Redox Signal
, vol.5
, pp. 731-740
-
-
Sabri, A.1
Hughie, H.H.2
Lucchesi, P.A.3
-
93
-
-
33644585112
-
Increased reactive oxygen species production and functional alterations in an-tioxidant enzymes in human failing myocardium
-
Sam F, Kerstetter DL, Pimental DR, Mulukutla S, Tabaee A, Bristow MR, Colucci WS, and Sawyer DB. Increased reactive oxygen species production and functional alterations in an-tioxidant enzymes in human failing myocardium. J Card Fail 11: 473-480, 2005.
-
(2005)
J Card Fail
, vol.11
, pp. 473-480
-
-
Sam, F.1
Kerstetter, D.L.2
Pimental, D.R.3
Mulukutla, S.4
Tabaee, A.5
Bristow, M.R.6
Colucci, W.S.7
Sawyer, D.B.8
-
94
-
-
0035903250
-
Mice lacking inducible nitric oxide synthase have improved left ventricular contractile function and reduced apoptotic cell death late after myocardial infarction
-
Sam F, Sawyer DB, Xie Z, Chang DL, Ngoy S, Brenner DA, Siwik DA, Singh K, Apstein CS, and Colucci WS. Mice lacking inducible nitric oxide synthase have improved left ventricular contractile function and reduced apoptotic cell death late after myocardial infarction. Circ Res 89: 351-356, 2001.
-
(2001)
Circ Res
, vol.89
, pp. 351-356
-
-
Sam, F.1
Sawyer, D.B.2
Xie, Z.3
Chang, D.L.4
Ngoy, S.5
Brenner, D.A.6
Siwik, D.A.7
Singh, K.8
Apstein, C.S.9
Colucci, W.S.10
-
95
-
-
0034617467
-
Role of reactive oxygen species and phosphatidylinositol 3-kinase in cardiomyocyte differentiation of embryonic stem cells
-
Sauer H, Rahimi G, Hescheler J, and Wartenberg M. Role of reactive oxygen species and phosphatidylinositol 3-kinase in cardiomyocyte differentiation of embryonic stem cells. FEBS Lett 476: 218-223, 2000.
-
(2000)
FEBS Lett
, vol.476
, pp. 218-223
-
-
Sauer, H.1
Rahimi, G.2
Hescheler, J.3
Wartenberg, M.4
-
96
-
-
0036545584
-
Role of oxidative stress in myocardial hypertrophy and failure
-
Sawyer DB, Siwik DA, Xiao L, Pimentel DR, Singh K, and Colucci WS. Role of oxidative stress in myocardial hypertrophy and failure. J Mol Cell Cardiol 34: 379-388, 2002.
-
(2002)
J Mol Cell Cardiol
, vol.34
, pp. 379-388
-
-
Sawyer, D.B.1
Siwik, D.A.2
Xiao, L.3
Pimentel, D.R.4
Singh, K.5
Colucci, W.S.6
-
97
-
-
0035845630
-
Endothelial nitric oxide synthase limits left ventricular remodeling after myocardial infarction in mice
-
Scherrer-Crosbie M, Ullrich R, Bloch KD, Nakajima H, Nasseri B, Aretz HT, Lindsey ML, Vancon AC, Huang PL, Lee RT, Zapol WM, and Picard MH. Endothelial nitric oxide synthase limits left ventricular remodeling after myocardial infarction in mice. Circulation 104: 1286-1291, 2001.
-
(2001)
Circulation
, vol.104
, pp. 1286-1291
-
-
Scherrer-Crosbie, M.1
Ullrich, R.2
Bloch, K.D.3
Nakajima, H.4
Nasseri, B.5
Aretz, H.T.6
Lindsey, M.L.7
Vancon, A.C.8
Huang, P.L.9
Lee, R.T.10
Zapol, W.M.11
Picard, M.H.12
-
98
-
-
20144368308
-
The FOXO3a transcription factor regulates cardiac myocyte size downstream of AKT signaling
-
Skurk C, Izumiya Y, Maatz H, Razeghi P, Shiojima I, Sandri M, Sato K, Zeng L, Schiekofer S, Pimentel D, Lecker S, Taegtmeyer H, Goldberg AL, and Walsh K. The FOXO3a transcription factor regulates cardiac myocyte size downstream of AKT signaling. J Biol Chem 280: 20814-20823, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 20814-20823
-
-
Skurk, C.1
Izumiya, Y.2
Maatz, H.3
Razeghi, P.4
Shiojima, I.5
Sandri, M.6
Sato, K.7
Zeng, L.8
Schiekofer, S.9
Pimentel, D.10
Lecker, S.11
Taegtmeyer, H.12
Goldberg, A.L.13
Walsh, K.14
-
99
-
-
54049090854
-
INOS in cardiac myocytes plays a critical role in death in a murine model of hypertrophy induced by calcineurin
-
Somers JR, Beck PL, Lees-Miller JP, Roach D, Li Y, Guo J, Loken S, Zhan S, Semeniuk L, and Duff HJ. iNOS in cardiac myocytes plays a critical role in death in a murine model of hypertrophy induced by calcineurin. Am J Physiol Heart Circ Physiol 295: H1122-H1131, 2008.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Somers, J.R.1
Beck, P.L.2
Lees-Miller, J.P.3
Roach, D.4
Li, Y.5
Guo, J.6
Loken, S.7
Zhan, S.8
Semeniuk, L.9
Duff, H.J.10
-
100
-
-
0033980347
-
Tumor necrosis factor-alpha induces apoptosis via inducible nitric oxide synthase in neonatal mouse cardiomyocytes
-
Song W, Lu X, and Feng Q. Tumor necrosis factor-alpha induces apoptosis via inducible nitric oxide synthase in neonatal mouse cardiomyocytes. Cardiovasc Res 45: 595-602, 2000.
-
(2000)
Cardiovasc Res
, vol.45
, pp. 595-602
-
-
Song, W.1
Lu, X.2
Feng, Q.3
-
101
-
-
0032498853
-
Time-dependent changes in matrix me-talloproteinase activity and expression during the progression of congestive heart failure: Relation to ventricular and myocyte function
-
Spinale FG, Coker ML, Thomas CV, Walker JD, Mukherjee R, and Hebbar L. Time-dependent changes in matrix me-talloproteinase activity and expression during the progression of congestive heart failure: relation to ventricular and myocyte function. Circ Res 82: 482-495, 1998.
-
(1998)
Circ Res
, vol.82
, pp. 482-495
-
-
Spinale, F.G.1
Coker, M.L.2
Thomas, C.V.3
Walker, J.D.4
Mukherjee, R.5
Hebbar, L.6
-
102
-
-
33947689707
-
Oxidative stress and growth-regulating intracellular signaling pathways in cardiac myocytes
-
Sugden PH and Clerk A. Oxidative stress and growth-regulating intracellular signaling pathways in cardiac myocytes. Antioxid Redox Signal 8: 2111-2124, 2006.
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 2111-2124
-
-
Sugden, P.H.1
Clerk, A.2
-
103
-
-
33745387361
-
2\+ currents via increased PI3Kalpha=PKB signaling
-
2\+ currents via increased PI3Kalpha=PKB signaling. Circ Res 98: 1390-1397, 2006.
-
(2006)
Circ Res
, vol.98
, pp. 1390-1397
-
-
Sun, H.1
Kerfant, B.G.2
Zhao, D.3
Trivieri, M.G.4
Oudit, G.Y.5
Pen-Ninger, J.M.6
Backx, P.H.7
-
104
-
-
0022542030
-
Developmental and functional adaptation of contractile proteins in cardiac and skeletal muscles
-
Swynghedauw B. Developmental and functional adaptation of contractile proteins in cardiac and skeletal muscles. Physiol Rev 66: 710-771, 1986.
-
(1986)
Physiol Rev
, vol.66
, pp. 710-771
-
-
Swynghedauw, B.1
-
105
-
-
58149387380
-
2\+ leak in chronic heart failure
-
2\+ leak in chronic heart failure. Circ Res 103: 1466-1472, 2008.
-
(2008)
Circ Res
, vol.103
, pp. 1466-1472
-
-
Terentyev, D.1
Gyorke, I.2
Belevych, A.E.3
Terentyeva, R.4
Sridhar, A.5
Nishijima, Y.6
De Blanco, E.C.7
Khanna, S.8
Sen, C.K.9
Car-Dounel, A.J.10
Carnes, C.A.11
Gyorke, S.12
-
106
-
-
33645067898
-
Bone marrow molecular alterations after myocardial infarction: Impact on endothelial progenitor cells
-
Thum T, Fraccarollo D, Galuppo P, Tsikas D, Frantz S, Ertl G, and Bauersachs J. Bone marrow molecular alterations after myocardial infarction: impact on endothelial progenitor cells. Cardiovasc Res 70: 50-60, 2006.
-
(2006)
Cardiovasc Res
, vol.70
, pp. 50-60
-
-
Thum, T.1
Fraccarollo, D.2
Galuppo, P.3
Tsikas, D.4
Frantz, S.5
Ertl, G.6
Bauersachs, J.7
-
107
-
-
0012449739
-
Mitogen-activated protein kinase pathways in redox signaling
-
Torres M. Mitogen-activated protein kinase pathways in redox signaling. Front Biosci 8: d369-d391, 2003.
-
(2003)
Front Biosci
, vol.8
-
-
Torres, M.1
-
108
-
-
20444497875
-
FOXO-dependent expression of the proa-poptotic protein Bim: Pivotal role for apoptosis signaling in endothelial progenitor cells
-
Urbich C, Knau A, Fichtlscherer S, Walter DH, Bruhl T, Potente M, Hofmann WK, de Vos S, Zeiher AM, and Dimmeler S. FOXO-dependent expression of the proa-poptotic protein Bim: pivotal role for apoptosis signaling in endothelial progenitor cells. FASEB J 19: 974-976, 2005.
-
(2005)
FASEB J
, vol.19
, pp. 974-976
-
-
Urbich, C.1
Knau, A.2
Fichtlscherer, S.3
Walter, D.H.4
Bruhl, T.5
Potente, M.6
Hofmann, W.K.7
De Vos, S.8
Zeiher, A.M.9
Dimmeler, S.10
-
109
-
-
70349368518
-
Novel role of NADPH oxidase in angiogenesis and stem=progenitor cell function
-
Ushio-Fukai M and Urao N. Novel role of NADPH oxidase in angiogenesis and stem=progenitor cell function. Antioxid Redox Signal 11: 2517-2533, 2009.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 2517-2533
-
-
Ushio-Fukai, M.1
Urao, N.2
-
110
-
-
0034640524
-
Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival
-
Wang X, McCullough KD, Franke TF, and Holbrook NJ. Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival. J Biol Chem 275: 14624-14631, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 14624-14631
-
-
Wang, X.1
McCullough, K.D.2
Franke, T.F.3
Holbrook, N.J.4
-
111
-
-
0024840101
-
Myocardial collagen remodeling in pressure overload hypertrophy. A case for interstitial heart disease
-
Weber KT, Jalil JE, Janicki JS, and Pick R. Myocardial collagen remodeling in pressure overload hypertrophy. A case for interstitial heart disease. Am J Hypertens 2: 931-940, 1989.
-
(1989)
Am J Hypertens
, vol.2
, pp. 931-940
-
-
Weber, K.T.1
Jalil, J.E.2
Janicki, J.S.3
Pick, R.4
-
112
-
-
0036083322
-
Role of reactive oxygen species and NAD(P)H oxidase in alpha(1)-adrenoceptor signaling in adult rat cardiac myocytes
-
Xiao L, Pimentel DR, Wang J, Singh K, Colucci WS, and Sawyer DB. Role of reactive oxygen species and NAD(P)H oxidase in alpha(1)-adrenoceptor signaling in adult rat cardiac myocytes. Am J Physiol Cell Physiol 282: C926-C934, 2002.
-
(2002)
Am J Physiol Cell Physiol
, vol.282
-
-
Xiao, L.1
Pimentel, D.R.2
Wang, J.3
Singh, K.4
Colucci, W.S.5
Sawyer, D.B.6
-
113
-
-
0032498185
-
Activation of the cardiac calcium release channel (ryanodine receptor) by poly-S-nitrosylation
-
Xu L, Eu JP, Meissner G, and Stamler JS. Activation of the cardiac calcium release channel (ryanodine receptor) by poly-S-nitrosylation. Science 279: 234-237, 1998.
-
(1998)
Science
, vol.279
, pp. 234-237
-
-
Xu, L.1
Eu, J.P.2
Meissner, G.3
Stamler, J.S.4
-
114
-
-
9144231898
-
Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling
-
Yamaguchi O, Higuchi Y, Hirotani S, Kashiwase K, Na-kayama H, Hikoso S, Takeda T, Watanabe T, Asahi M, Taniike M, Matsumura Y, Tsujimoto I, Hongo K, Kusakari Y, Kurihara S, Nishida K, Ichijo H, Hori M, and Otsu K. Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling. Proc Natl Acad Sci \USA 100: 15883-15888, 2003.
-
(2003)
Proc Natl Acad Sci \USA
, vol.100
, pp. 15883-15888
-
-
Yamaguchi, O.1
Higuchi, Y.2
Hirotani, S.3
Kashiwase, K.4
Na-Kayama, H.5
Hikoso, S.6
Takeda, T.7
Watanabe, T.8
Asahi, M.9
Taniike, M.10
Matsumura, Y.11
Tsujimoto, I.12
Hongo, K.13
Kusakari, Y.14
Kurihara, S.15
Nishida, K.16
Ichijo, H.17
Hori, M.18
Otsu, K.19
-
115
-
-
0034688195
-
Vitamin E supplementation and cardiovascular events in high-risk patients
-
DOI 10.1056/NEJM200001203420302
-
Yusuf S, Dagenais G, Pogue J, Bosch J, and Sleight P. Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 342: 154-160, 2000. (Pubitemid 30051646)
-
(2000)
New England Journal of Medicine
, vol.342
, Issue.3
, pp. 154-160
-
-
Yusuf, S.1
-
116
-
-
33749515825
-
Nitroso-redox interactions in the cardiovascular system
-
Zimmet JM and Hare JM. Nitroso-redox interactions in the cardiovascular system. Circulation 114: 1531-1544, 2006.
-
(2006)
Circulation
, vol.114
, pp. 1531-1544
-
-
Zimmet, J.M.1
Hare, J.M.2
|