α-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes is mediated via thioredoxin-1-sensitive oxidative modification of thiols on ras

Circulation

Volumn 111, Issue 9, 2005, Pages 1192-1198

  Kuster, Gabriela M ^a   Pimentel, David R ^a   Adachi, Takeshi ^a   Ido, Yasuo ^a   Brenner, Daniel A ^a   Cohen, Richard A ^a   Liao, Ronglih ^a   Siwik, Deborah A ^a   Colucci, Wilson S ^a  

^a BOSTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Hypertrophy; Reactive oxygen species; Receptors, adrenergic, alpha; Sulfhydryl compounds; Thioredoxin

Indexed keywords

ADENOVIRUS VECTOR; ALPHA ADRENERGIC RECEPTOR; AZELAIC ACID; BETA GALACTOSIDASE; CATALASE; DICHLOROFLUORESCEIN; DITHIOTHREITOL; ENZYME INHIBITOR; IODOACETAMIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PEROXIDASE; RAS PROTEIN; REACTIVE OXYGEN METABOLITE; THIOL DERIVATIVE; THIOREDOXIN;

ANIMAL CELL; ARTICLE; BIOTINYLATION; CONTROLLED STUDY; ENZYME ACTIVITY; FLUORESCENCE; GENE OVEREXPRESSION; HEART MUSCLE CELL; HEART VENTRICLE; MALE; MUSCLE HYPERTROPHY; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; SARCOMERE;

ANIMALS; CATALASE; CYSTEINE; DICARBOXYLIC ACIDS; DITHIOTHREITOL; ENZYME ACTIVATION; HEART VENTRICLES; HYPERTROPHY; MALE; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYOCYTES, CARDIAC; NOREPINEPHRINE; OXIDATION-REDUCTION; PEROXIDASE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS P21(RAS); RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTORS, ADRENERGIC, ALPHA; RECOMBINANT FUSION PROTEINS; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; SARCOMERES; SIGNAL TRANSDUCTION; SULFHYDRYL COMPOUNDS; THIOREDOXIN;

EID: 14944371448     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000157148.59308.F5     Document Type: Article

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