In vivo evaluation of doxorubicin-loaded polymeric micelles targeting folate receptors and early endosomal pH in drug-resistant ovarian cancer

Molecular Pharmaceutics

Volumn 6, Issue 5, 2009, Pages 1353-1362

  Kim, Dongin ^a   Zhong, Gao Gao ^a   Eun, Seong Lee ^a   You, Han Bae ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

Endosomal pH targeting; Folate receptor targeting; Multidrug resistance (MDR); Ovarian cancer; pH sensitive micelle

Indexed keywords

COPOLYMER; DOXORUBICIN; DRUG CARRIER; FOLATE RECEPTOR; POLY(HISTIDINE CO PHENYLALANINE); POLYGLACTIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG FORMULATION; DRUG RETENTION; ENDOSOME; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MICELLE; MOUSE; NONHUMAN; OVARY CANCER; PH MEASUREMENT; PH SENSITIVE MICELLE; PHYSICAL CHEMISTRY; POLYMERIZATION; PRIORITY JOURNAL; REACTION OPTIMIZATION;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CARRIER PROTEINS; CELL LINE, TUMOR; DOXORUBICIN; DRUG CARRIERS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; ENDOSOMES; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; INJECTIONS, INTRAVENOUS; MICE; MICE, NUDE; MICELLES; NEOPLASM TRANSPLANTATION; OVARIAN NEOPLASMS; POLYESTERS; POLYETHYLENE GLYCOLS; POLYMERS; PROTEINS; RECEPTORS, CELL SURFACE; TISSUE DISTRIBUTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 70350057605     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp900021q     Document Type: Conference Paper

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