Thermosensitive and biodegradable polymeric micelles for paclitaxel delivery

Journal of Controlled Release

Volumn 103, Issue 2, 2005, Pages 341-353

  Soga, Osamu ^a   Van Nostrum, Cornelus F ^a   Fens, Marcel ^a   Rijcken, Cristianne J F ^a   Schiffelers, Raymond M ^a   Storm, Gert ^a   Hennink, Wim E ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Biodegradable; Cancer; Drug delivery; Paclitaxel; Polymeric micelle; Taxol; Thermosensitive

Indexed keywords

DISSOLUTION; ETHANOL; HYDROLYSIS; PH EFFECTS; POLYMERS; REACTION KINETICS; SOLUTIONS; TRANSMISSION ELECTRON MICROSCOPY;

CYTOTOXITY; LACTIC ACIDS; PACLITAXEL (PTX); SERUM PROTEINS;

MICELLES;

COPOLYMER; CREMOPHOR; LACTIC ACID; PACLITAXEL; POLY[N (2 HYDROXYPROPYL)METHACRYLAMIDE LACTATE] BLOCK POLY(ETHYLENE GLYCOL); UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIODEGRADABILITY; CONCENTRATION RESPONSE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG MECHANISM; DRUG SOLUBILITY; DRUG STABILITY; HEAT SENSITIVITY; HYDROLYSIS; MICELLIZATION; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOCOMPATIBLE MATERIALS; CELL LINE, TUMOR; CELL SURVIVAL; DRUG CARRIERS; DRUG COMPOUNDING; DRUG STABILITY; LACTIC ACID; MICE; MICELLES; PACLITAXEL; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYMETHACRYLIC ACIDS; SOLUBILITY; TEMPERATURE;

EID: 14844286179     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2004.12.009     Document Type: Article

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