Differential conjugation of tat peptide to superparamagnetic nanoparticles and its effect on cellular uptake

Bioconjugate Chemistry

Volumn 13, Issue 4, 2002, Pages 840-844

  Zhao, Ming ^a   Kircher, Moritz F ^a   Josephson, Lee ^a   Weissleder, Ralph ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IRON OXIDES; NANOPARTICLES; PEPTIDES; SULFUR COMPOUNDS; SUPERPARAMAGNETISM; SURFACE TREATMENT;

CELL TYPES; CELLULAR UPTAKE; CONTRAST AGENT; HIV-1 TAT; INTRACELLULAR DELIVERY; MAGNETIC LABELING; SUPERPARAMAGNETIC NANOPARTICLES; SUPERPARAMAGNETICS; SURFACE-MODIFICATION; TAT PEPTIDE;

MAGNETIC RESONANCE IMAGING;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

CONTRAST MEDIUM; FERRIC ION; FERRIC OXIDE; PEPTIDE FRAGMENT; TRANSACTIVATOR PROTEIN;

ANIMAL; ARTICLE; C57BL MOUSE; CHEMISTRY; DRUG DELIVERY SYSTEM; LYMPHOCYTE; MAGNETISM; METABOLISM; METHODOLOGY; MOUSE; NANOTECHNOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PARTICLE SIZE; SENSITIVITY AND SPECIFICITY; STANDARD; SYNTHESIS;

ANIMALS; CONTRAST MEDIA; DRUG DELIVERY SYSTEMS; FERRIC COMPOUNDS; GENE PRODUCTS, TAT; LYMPHOCYTES; MAGNETIC RESONANCE IMAGING; MAGNETICS; MICE; MICE, INBRED C57BL; NANOTECHNOLOGY; PARTICLE SIZE; PEPTIDE FRAGMENTS; SENSITIVITY AND SPECIFICITY;

EID: 0036074845     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc0255236     Document Type: Article

References (14)

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8. Introduction of soluble proteins into the MHC class I pathway by conjugation to an HIV tat peptide
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11. Intracellular magnetic labeling of lymphocytes for in vivo trafficking studies
12. A simple spectrophotometric determination of solid supported amino groups
13. The HIV-1 Tat nuclear localization sequence confers novel nuclear import properties
14. Superparamagnetic iron oxide: Pharmacokinetics and toxicity