Clonazepam release from core-shell type nanoparticles in vitro

Journal of Controlled Release

Volumn 51, Issue 2-3, 1998, Pages 169-178

  Jeong, Young Il ^a   Cheon, Jae Bok ^a   Kim, Sung Ho ^b   Nah, Jae Woon ^c   Lee, Young Moo ^d   Sung, Yong Kiel ^e   Akaike, Toshihiro ^f   Cho, Chong Su ^a  

^a Chonnam National University   (South Korea)

^b Chosun University   (South Korea)

^c Sunchon National University   (South Korea)

^d Hanyang University   (South Korea)

^e Dongguk University   (South Korea)

^f TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Clonazepam release; Core shell nanoparticles; In vitro studies

Indexed keywords

CLONAZEPAM; COPOLYMER; MACROGOL; NANOPARTICLE; POLY GAMMA BENZYL GLUTAMATE; UNCLASSIFIED DRUG;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SYNTHESIS; FLUORESCENCE SPECTROSCOPY; LIGHT SCATTERING; MICELLE; PARTICLE SIZE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY;

ANTICONVULSANTS; CALORIMETRY, DIFFERENTIAL SCANNING; CLONAZEPAM; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; MICELLES; PARTICLE SIZE; POLYGLUTAMIC ACID; SODIUM DODECYL SULFATE; SPECTROMETRY, FLUORESCENCE;

EID: 0032509920     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(97)00163-6     Document Type: Article

References (34)

1. Bador H., Ringsdorf H., Schmidt B. Water soluble polymers in medicine. Angew. Makromol. Chem. 123/124:1984;457-485.
2. Davis S.S., Illum L., Moghimi S.M., Davies M.C., Porter C.J.H., Muir I.S., Brindley A., Christy N.M., Norman M.E., Williams P., Dunn S.E. Microspheres for targeting drugs to specific body sites. J. Control. Rel. 24:1993;157-163.
3. Kopecek J. The potential of water-soluble polymeric carriers in targeted and site-specific drug delivery. J. Control. Rel. 11:1990;279-290.
4. Lasic D.D. Mixed micelles in drug delivery. Nature. 355:1992;279-280.
5. Blume G., Cevc G., Crommelin M.D.J.A., Bakker-Woudenberg I.A.J.M., Kluft C., Storm G. Specific targeting with poly(ethylene glycol)-modified liposomes: coupling of homing devices to the ends of the polymeric chains combines effective target binding with long circulation times. Biochim. Biophys. Acta. 1149:1993;180-184.
6. Leroux J.C., Allemann E., Jaeghere F.D., Doelker E., Gurny R. Biodegradable nanoparticles - From sustained release formulations to improved site specific drug delivery. J. Control. Rel. 39:1996;339-350.
7. Gref R., Minamitake Y., Peracchia M.T., Trubetskoy V., Torchilin V., Langer R. Biodegradable long-circulating polymeric nanospheres. Science. 263:1994;1600-1603.
8. Yokoyama M., Miyauchi M., Yamada N., Okano T., Sakurai Y., Kataoka K., Inoue S. Polymer micelles as novel drug carrier: adriamycin-conjugated poly(ethylene gylcol)-poly(aspartic acid) block copolymer. J. Control. Rel. 11:1990;269-278.
9. Kataoka K., Kwon G.S., Yokoyama M., Okano T., Sakurai Y. Block copolymer micelles as vehicles for drug delivery. J. Control. Rel. 24:1993;119-132.
10. Cammas S., Kataoka K. Functional poly[(ethylene oxide)-co-(β-benzyl-L-aspartate)] polymeric micelles: block copolymer synthesis and micelles formation. Macromol. Chem. Phys. 196:1995;1899-1905.
11. Hruska Z., Riess G., Goddard P. Synthesis and purification of a poly(ethylene oxide)-poly(γ-benzyl-L-glutamate) diblock copolymer bearing tyrosine units at the block junction. Polymer. 34:1993;1333-1335.
12. Brown W., Schillen K., Almgren M., Hvidt S., Bahadur P. Micelle and gel formation in a poly(ethylene oxide)/poly(propylene oxide)/poly(ethylene oxide) triblock copolymer in water solution. Dynamic and static light scattering and oscillatory shear measurements. J. Phys. Chem. 95:1991;1850-1858.
13. Kwon G.S., Naito M., Yokoyama M., Okano T., Sakurai Y., Kataoka K. Physical entrapment of adriamycin in AB block copolymer micelles. Pharm. Res. 12:1995;192-195.
14. Kwon G.S., Yokoyama M., Okano T., Sakurai Y., Kataoka K. Biodistribution of micelle-forming polymer-drug conjugates. Pharm. Res. 11:1993;970-974.
15. Kwon G., Suwa S., Yokoyama M., Okano T., Sakurai Y., Kataoka K. Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly(ethlene oxide-aspartate) block copolymer-adriamycin conjugates. J. Control. Rel. 29:1994;17-23.
16. Hayashi T., Iwatsuki M. Biodegradation of copoly(L-aspartic acid/L-glutamic acid) in vitro. Biopolymer. 29:1990;549-557.
17. Cho C.S., Kim S.U. Biodegradation of poly(γ-benzyl L-glutamate)/poly (ethylene glycol) block copolymer in vitro. J. Control. Rel. 7:1988;283-286.
18. Lee J.H., Kopecek J., Andrade J.D. Protein-resistant surfaces prepared by PEO-containing block copolymer surfactants. J. Biomed. Mater. Res. 23:1989;351-368.
19. Mura P., Liguori A., Bramanti G., Corti P., Murratzu C., Celesti L. In vitro study of clonazepam diffusion kinetics from solutions or hydrophilic gel. Pharm. Acta Helv. 65:1990;298-303.
20. th Edition, Vol. 2, Mack Publishing Company, Easton, Pennsylvania, USA, 1995, pp. 1173-1174.
21. Cho C.S., Kim S.W., Komoto T. Synthesis and structural study of an ABA block copolymer consisting of poly(γ-benzyl L-glutamate) as the A block and poly(ethylene oxide) as the B block. Macromol. Chem. 191:1990;981-991.
22. Cho C.S., Jo B.W., Kwon J.K., Komoto T. Synthesis and structural study of an ABA block copolymer consisting of poly(ε-benzyloxycarbonyl-L-lysine) as the A block and poly(ethylene oxide) as the B block. Macromol. Chem. Phys. 195:1994;2195-2206.
23. Cho, C.S., Chung, S.J., Goto, M., Kobayashi, A., Akaike, T., Synthesis of poly(γ-benzyl L-glutamate)/poly(ethylene oxide) diblock copolymer encapped with sugar moiety for cell-specific biomaterials Chem. Lett. (1994) 1817-1820.
24. Cho C.S., Na J.W., Jeong Y.I., Kim S.H., Lee Y.M., Sung Y.K. Micelle formation of the hexablock copolymer consisting of poly(γ-benzyl L-glutamate) as the hydrophobic part and poly(ethylene oxide) as the hydrophilic part. Polymer (Korea). 19:1995;926-931.
25. Kalyanasundaram K., Thomas J.K. Environmental effects on vibronic band intensities in pyrene monomer fluorescence and their application in studies in micellar systems. J. Am. Chem. Soc. 99:1977;2039-2044.
26. Wilhelm M., Zhao C.L., Wang Y., Xu R., Winnik M.A., Mura J.L., Riess G., Croucher M.D. Poly(styrene-ethylene oxide) block copolymer micelle formation in water: a fluorescence probe study. Macromolecules. 24:1991;1033-1040.
27. Marctic P.A., Nair M. Microevironment sensing of block copolymer micelles by fluorescence spectroscopy. J. Colloids Interface Sci. 163:1994;517-519.
28. Kwon G.S., Naito M., Yokoyama M., Okano T., Sakurai Y., Kataoka K. Polymeric micelles based on AB block copolymers of poly(ethylene oxide) and poly(β-benzyl L-aspartate). Langmuir. 9:1993;945-949.
29. Goodman M., Hutchison J. The mechanisms of polymerization of N-unsubstituted N-carboxyanhydride. J. Am. Chem. Soc. 88:1966;3627-3630.
30. Bahadur P., Sastry N.V., Rao Y.K. Interaction studies of styrene-ethylene oxide block copolymers with ionic surfactants in aqueous solutions. Colloids and Surfaces. 29:1988;343-358.
31. Xu R., Winnik M.A., Hallett F.R., Riess G., Croucher M.O. Light scattering study of the association behavior of styrene-ethylene oxide block copolymers in aqueous solution. Macromolecules. 24:1991;87-93.
32. Gao Z., Eisenberg A. A model of micellization for block copolymers in solutions. Macromolecules. 26:1993;7353-7360.
33. Cho C.S., Cheon J.B., Jeong Y.I., Kim I.S., Kim S.H., Akaike T. Novel core-shell type thermo-sensitive nanoparticles composed of poly(γ-benzyl L-glutamate) as the core and poly(N-isopropylacrylamide) as the shell. Macromol. Rapid Commun. 18:1997;361-369.
34. La S.B., Okano T., Kataoka K. Preparation and characterization of the micelle-forming polymeric drug indomethacin-incorporated poly(ethylene oxide)-poly(β-benzyl L-aspartate) block copolymer micelles. J. Pharm. Sci. 85:1996;85-90.