Polymeric micelles of poly(2-ethyl-2-oxazoline)-block-poly(ε-caprolactone) copolymer as a carrier for paclitaxel

Journal of Controlled Release

Volumn 89, Issue 3, 2003, Pages 437-446

  Lee, Sang Cheon ^a   Kim, Chulhee ^a   Kwon, Ick Chan ^b   Chung, Hesson ^b   Jeong, Seo Young ^b  

^a Inha University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

Author keywords

Amphiphilic block copolymers; Cell growth inhibition; Hemolysis; Paclitaxel; Poly(2 ethyl 2 oxazoline); Polymeric micelles

Indexed keywords

ACETONITRILE; CELLS; DIALYSIS; DRUG PRODUCTS; HYDROPHOBICITY; LIPIDS; MICELLES; NUCLEAR MAGNETIC RESONANCE; ONCOLOGY; ORGANIC SOLVENTS; TOXICITY;

HEMOLYSIS;

BLOCK COPOLYMERS;

ACETONITRILE; COPOLYMER; CREMOPHOR; DRUG CARRIER; ORGANIC SOLVENT; PACLITAXEL; POLY(2 ETHYL 2 OXAZOLINE); POLYCAPROLACTONE; POLYSORBATE 80; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CANCER CELL; CELL GROWTH; CELL PROLIFERATION; CYTOTOXICITY; DIALYSIS; DRUG EFFECT; DRUG FORMULATION; DRUG SYNTHESIS; GROWTH INHIBITION; HEMOLYSIS; HUMAN; HUMAN CELL; HYDRODYNAMICS; HYDROPHOBICITY; IN VITRO STUDY; LIPID MEMBRANE; MICELLE; MOLECULAR SIZE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SQUAMOUS CELL CARCINOMA;

EID: 0038064275     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(03)00162-7     Document Type: Article

References (37)

1. Spencer C.M., Faulds D. Paclitaxel: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of cancer. Drugs. 48:1994;794-847.
2. Rowinsky E.K., Onetto N., Canetta R.M., Arbuck S.G. Taxol: the first of the taxanes, an important new class of antitumor agents. Semin. Oncol. 19:1992;646-662.
3. Lilenbaum R.C., Green M.R. Novel chemotherapeutic agents in the treatment of non-small cell lung cancer. J. Clin. Oncol. 11:1993;1391-1402.
4. Thipgen J.T., Blessing J.A., Ball H., Hummel S.J., Barrett R.J. Phase II trial of paclitaxel in patients with progressive ovarian carcinoma after platinum-based chemotherapy: a gynaecologic oncology group study. J. Clin. Oncol. 12:1994;1748-1753.
5. Schiff P., Fant J., Horwitz S.B. Promotion of microtubule assembly in vitro by taxol. Nature. 277:1979;665-667.
6. Schiff P., Horwitz S.B. Taxol stabilizes microtubules in mouse fibroblast cells. Proc. Natl. Acad. Sci. USA. 77:1980;1561-1565.
7. Rowinsky E.K., Donehower R.C., Jones R.J., Tucker R.W. Microtubule changes and cytotoxicity in leukemic cell lines treated with taxol. Cancer Res. 48:1988;4093-4100.
8. Liggins R.T., Hunter W.L., Burt H.M. Solid-state characterization of paclitaxel. J. Pharm. Sci. 86:1997;1458-1463.
9. NCI Investigational Drugs, Pharmaceutical data, 1990, pp. 151-152.
10. Onetto N., Canett R., Winograd B., Catane R., Dougan M., Grechko J., et al. Overview of taxol safety. J. Natl. Cancer Inst. Monogr. 15:1993;131-139.
11. Mazzo D., Nguyen Huu J.J., Pagniez S., Denis P. Compatibility of docetaxel and paclitaxel in intravenous solutions with polyvinyl chloride infusion materials. Am. J. Health Syst. Pharm. 54:1997;566-569.
12. Gregory R., DeLisa A.F. Paclitaxel: a new antineoplastic agent for refractory ovarian cancer. Clin. Pharm. 12:1993;401-415.
13. Crosasso P., Ceruti M., Brusa P., Arpicco S., Dosio F., Cattel L. Preparation, characterization and properties of sterically stabilized paclitaxel-containing liposomes. J. Controlled Release. 63:2000;19-30.
14. Sharma A., Straubinger R.M. Novel taxol formulations: Preparation and characterization of taxol-containing liposomes. Pharm. Res. 11:1994;889-896.
15. Dordunoo S.K., Burt H.M. Solubility and stability of taxol: Effects of buffer and cyclodextrins. Int. J. Pharm. 133:1996;191-201.
16. Tarr B.D., Sambandan T.G., Yalkowsky S.H. A new parenteral emulsion for the administration of taxol. Pharm. Res. 4:1987;162-165.
17. Alkan-Onyuksel H., Ramakrishnan S., Chai H.-B., Pezzuto J.M. A mixed micellar formulation suitable for the parenteral administration of taxol. Pharm. Res. 11:1994;206-212.
18. Dordunoo S.K., Jackson J.K., Arsenault L.A., Oktaba A.M.C., Hunter W.L., Burt H.M. Taxol encapsulation in poly(ε-caprolactone) microspheres. Cancer Chemother. Pharmacol. 36:1995;279-282.
19. Wang Y.M., Sato H., Adachi I., Horikoshi I. Preparation and characterization of poly(lactic-co-glycolic acid) microspheres for targeted delivery of a novel anticancer agent, taxol. Chem. Pharm. Bull. 44:1996;1935-1940.
20. Burt H.M., Zhang X., Toleikis P., Embree L., Hunter W.L. Development of copolymers of poly(D,Llactide) and methoxypolyethylene glycol as micellar carriers of paclitaxel. Colloids Surf. B: Biointerfaces. 16:1999;161-171.
21. Zhang X., Jackson J.K., Burt H.M. Development of amphiphilic diblock copolymers as micellar carriers of taxol. Int. J. Pharm. 132:1996;195-206.
22. Zhang X., Burt H.M., Von Hoff D., Dexter D., Mangold G., Degen D., et al. An investigation of the antitumor activity and biodistribution of polymeric micellar paclitaxel. Cancer Chemother. Pharmacol. 40:1997;81-86.
23. Kataoka K., Kwon G.S., Yokoyama M., Okano T., Sakurai Y. Block copolymer micelles as vehicles for drug delivery. J. Controlled Release. 24:1993;119-132.
24. Kwon G.S., Naito M., Yokoyama M., Pkano T., Sakurai Y., Kataoka K. Physical entrapment of adriamycin in ab block copolymer micelles. Pharm. Res. 12:1995;192-195.
25. Kabanov A.V., Batrakova E.V., Melik-Nubarov N.S., Fedoseev N.A., Dorodnich T.Y., Alakhov V.Y., et al. A new class of drug carriers: micelles of poly(oxyethylene)-poly(oxypropylene) block copolymers as microcontainers for drug targeting from in brain. J. Controlled Release. 22:1992;141-158.
26. Allen C., Maysinger D., Eisenberg A. Nano-engineering block copolymer aggregates for drug delivery. Colloids Surf. B: Biointerfaces. 16:1999;3-27.
27. Yokoyama M., Okano T., Sakurai Y., Fukushima S., Okamoto K., Kataoka K. Selective delivery of adriamycin to a solid tumor using a polymeric micelle carrier system. J. Drug Target. 7:1999;171-186.
28. Lee S.C., Chang Y., Yoon J.-S., Kim C., Kwon I.C., Kim Y.-H., et al. Synthesis and micellar characterization of amphiphilic diblock copolymers based on poly(2-ethyl-2-oxazoline) and aliphatic polyesters. Macromolecules. 32:1999;1847-1852.
29. Kim C., Lee S.C., Kang S.W., Kwon I.C., Jeong S.Y. Phase-transition characteristics of amphiphilic poly(2-ethyl-2-oxazoline)/poly(ε-caprolactone) block copolymers in aqueous solutions. J. Polym. Sci., Polym. Phys. 38:2000;2400-2408.
30. Kim C., Lee S.C., Shin J.H., Yoon J.-S., Kwon I.C., Jeong S.Y. Amphiphilic diblock copolymers based on poly(2-ethyl-2-oxazoline) and poly(1,3-trimethylene carbonate): synthesis and micellar characteristics. Macromolecules. 33:2000;7448-7452.
31. Kwon I.C., Bae Y.H., Kim S.W. Electrically erodible polymer gel for controlled release of drugs. Nature. 354:1991;291-293.
32. Kim C., Lee S.C., Kwon I.C., Chung H., Jeong S.Y. Complexation of poly(2-ethyl-2-oxazoline)-block-poly(ε-caprolactone) micelles with multifunctional carboxylic acids. Macromolecules. 35:2002;193-200.
33. Goddard P., Hutchinson L.E., Brown J., Brookman L.J. Soluble polymeric carriers for drug delivery. Part 2. Preparation and in vivo behavior of N-acylethyleneimine copolymers. J. Controlled Release. 10:1989;5-16.
34. Yu B.G., Okano T., Kataoka K., Kwon G. Polymeric micelles for drug delivery: solubilization and haemolytic activity of amphotericin B. J. Controlled Release. 53:1998;131-136.
35. Sato H., Wang Y.M., Adachi I., Horikoshi I. Pharmacokinetic study of taxol-loaded poly(lactic-co-glycolic acid) microspheres containing isopropyl myristate after targeted delivery to the lung in mice. Biol. Pharm. Bull. 19:1996;1596-1601.
36. Allen C., Yu Y., Maysinger D., Eisenberg A. Polycaprolactone-b-poly(ethylene oxide) block copolymer micelles as a novel drug delivery vehicle for neurotrophic agents FK506 and L-685,818. Bioconjug. Chem. 9:1998;564-572.
37. Miwa A., Ishibe A., Nakano M., Yamahira T., Itai S., Jinno S., et al. Development of novel chitosan derivatives as micellar carriers of taxol. Pharm. Res. 15:1998;1844-1850.