Cytochrome P450-dependent eicosapentaenoic acid metabolites are novel BK channel activators

Hypertension

Volumn 39, Issue 2 II, 2002, Pages 609-613

  Lauterbach, Birgit ^a   Barbosa Sicard, Eduardo ^a   Wang, Mong Heng ^a   Honeck, Horst ^a   Kärgel, Eva ^a   Theuer, Jürgen ^a   Schwartzman, Michal L ^a   Haller, Hermann ^a   Luft, Friedrich C ^a   Gollasch, Maik ^a   Schunck, Wolf Hagen ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

Cytochrome P450; Endothelium derived factors; Potassium channels; Vascular smooth muscle cells

Indexed keywords

4 AMINOPYRIDINE; ARACHIDONIC ACID DERIVATIVE; CYTOCHROME P450; CYTOCHROME P450 4A1; CYTOCHROME P450 4A3; EPOXYICOSATRIENOIC ACID; ICOSAPENTAENOIC ACID; POTASSIUM CHANNEL; POTASSIUM CHANNEL STIMULATING AGENT; RECOMBINANT ENZYME; TETRYLAMMONIUM; UNCLASSIFIED DRUG; VASOACTIVE AGENT;

ANIMAL TISSUE; BRAIN ARTERY; CHEMICAL BOND; CONFERENCE PAPER; CONTROLLED STUDY; ENANTIOMER; MALE; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEREOISOMERISM;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; EICOSAPENTAENOIC ACID; ELECTROPHYSIOLOGY; ENDOTHELIUM, VASCULAR; ISOENZYMES; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MALE; OXIDATION-REDUCTION; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; RATS; RATS, SPRAGUE-DAWLEY;

EID: 18244378308     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/hy0202.103293     Document Type: Conference Paper

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