메뉴 건너뛰기




Volumn 9, Issue 3, 2010, Pages 158-172

Current and future treatment options in idiopathic pulmonary fibrosis

Author keywords

Acetylcysteine; Azathioprine; Glucocorticosteroid; Idiopathic pulmonary fibrosis; Treatment

Indexed keywords

ACETYLCYSTEINE; ANTICOAGULANT AGENT; ANTIFIBROTIC AGENT; AZATHIOPRINE; BIBF 1120; BOSENTAN; COLCHICINE; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN; ENDOTHELIN RECEPTOR ANTAGONIST; FG 3019; GAMMA INTERFERON; GAMMA INTERFERON 1BETA; GLUCOCORTICOID; HEPARIN; IMATINIB; METHOTREXATE; METHYLPREDNISOLONE; MS 80; PENICILLAMINE; PHENPROCOUMON; PIRFENIDONE; PLACEBO; PREDNISONE; THALIDOMIDE; TRANSFORMING GROWTH FACTOR BETA ANTIBODY; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZILEUTON;

EID: 77958475711     PISSN: 18715281     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152810792231878     Document Type: Article
Times cited : (21)

References (166)
  • 1
    • 0031783604 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Survival in population based and hospital based cohorts
    • Maple, D. W.; Hunt, W. C.; Utton, R.; Baumgartner, K. B.; Samet, J. M.; Coultas, D. B. Idiopathic pulmonary fibrosis: survival in population based and hospital based cohorts. Thorax, 1998, 53(6), 469-476.
    • (1998) Thorax , vol.53 , Issue.6 , pp. 469-447
    • Maple, D.W.1    Hunt, W.C.2    Utton, R.3    Baumgartner, K.B.4    Samet, J.M.5    Coultas, D.B.6
  • 2
    • 0033983168 scopus 로고    scopus 로고
    • Lung cancer and cryptogenic fibrosing alveolitis. A population-based cohort study
    • Hubbard, R.; Venn, A.; Lewis, S.; Britton, J. Lung cancer and cryptogenic fibrosing alveolitis. A population-based cohort study. Am. J. Respir. Crit. Care Med., 2000, 161(1), 5-8.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , Issue.1 , pp. 5-8
    • Hubbard, R.1    Venn, A.2    Lewis, S.3    Britton, J.4
  • 5
    • 0034011982 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Diagnosis and treatment. International consensus statement
    • American Thoracic Society, American Thoracic Society (ATS) and the European Respiratory Society (ERS)
    • American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS) and the European Respiratory Society (ERS). Am. J. Respir. Crit. Care Med., 2000, 161(2), 646-64.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , Issue.2 , pp. 646-664
  • 7
    • 0037080547 scopus 로고    scopus 로고
    • American Thoracic Society/European Respiratory Society international multidisciplinary consensus classification of the idiopathic interstitial pneumonias
    • American Thoracic Society/European Respiratory Society
    • American Thoracic Society/European Respiratory Society. American Thoracic Society/European Respiratory Society international multidisciplinary consensus classification of the idiopathic interstitial pneumonias. Am. J. Respir. Crit. Care Med., 2002, 165(2), 277-304.
    • (2002) Am. J. Respir. Crit. Care Med. , vol.165 , Issue.2 , pp. 277-304
  • 8
    • 0017172219 scopus 로고
    • Idiopathic pulmonary fibrosis. Clinical, histologic, radiographic, physiologic, scintigraphic, cytologic, and biochemical aspects
    • Crystal, R. G.; Fulmer, J. D.; Roberts, W. C.; Moss, M. L.; Line, B. R.; Reynolds, H. Y. Idiopathic pulmonary fibrosis. Clinical, histologic, radiographic, physiologic, scintigraphic, cytologic, and biochemical aspects. Ann. Intern. Med., 1976, 85(6), 769-88.
    • (1976) Ann. Intern. Med. , vol.85 , Issue.6 , pp. 769-788
    • Crystal, R.G.1    Fulmer, J.D.2    Roberts, W.C.3    Moss, M.L.4    Line, B.R.5    Reynolds, H.Y.6
  • 9
    • 0020046932 scopus 로고
    • Alveolitis: The key to interstitial lung disorders
    • Keogh, B. A.; Crystal, R. G. Alveolitis: the key to interstitial lung disorders. Thorax, 1982, 37(1), 1-10.
    • (1982) Thorax , vol.37 , Issue.1 , pp. 1-10
    • Keogh, B.A.1    Crystal, R.G.2
  • 10
    • 0035895243 scopus 로고    scopus 로고
    • American Thoracic Society; European Respiratory Society; American College of Chest Physicians. Idiopahtic pulmonary fibrosis: Prevailing and evolving hypotheses about its pathogenesis and implications for therapy
    • Selman, M.; King, T. E.; Pardo, A; American Thoracic Society; European Respiratory Society; American College of Chest Physicians. Idiopahtic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann. Intern. Med., 2001, 134(2), 136-51.
    • (2001) Ann. Intern. Med. , vol.134 , Issue.2 , pp. 136-151
    • Selman, M.1    King, T.E.2    Pardo, A.3
  • 11
    • 70449440734 scopus 로고    scopus 로고
    • New mechanisms of pulmonary fibrosis
    • Strieter, R. M.; Mehrad, B. New mechanisms of pulmonary fibrosis. Chest, 2009, 136(5), 1364-70.
    • (2009) Chest , vol.136 , Issue.5 , pp. 1364-1370
    • Strieter, R.M.1    Mehrad, B.2
  • 12
    • 0027818981 scopus 로고
    • Basis of cutaneous wound repair
    • Clark, R. A. Basis of cutaneous wound repair. J. Dermatol. Surg. Oncol., 1993, 19(8), 693-706.
    • (1993) J. Dermatol. Surg. Oncol. , vol.19 , Issue.8 , pp. 693-706
    • Clark, R.A.1
  • 13
    • 70449434275 scopus 로고    scopus 로고
    • 4th ed.; Mason, R. J.; Broaddus, V. C.; Murray, J. F., Eds, Elsevier Saunders: Philadelphia, PA
    • Keane, M. P.; Belperio, J. A.; Henson, P. M. In Textbook of respiratory medicine 4th ed.; Mason, R. J.; Broaddus, V. C.; Murray, J. F., Eds.; Elsevier Saunders: Philadelphia, PA, 2005, pp. 449-90.
    • (2005) Textbook of Respiratory Medicine , pp. 449-490
    • Keane, M.P.1    Belperio, J.A.2    Henson, P.M.3
  • 14
    • 34147157791 scopus 로고    scopus 로고
    • Inflammation-associated remodelling and fibrosis in the lung - a process and an end point
    • Wallace, W. A. H.; Fitch, P. M.; Simpson, J. A.; Howie, S. E. M. Inflammation-associated remodelling and fibrosis in the lung - a process and an end point. Int. J. Exp. Pathol., 2007, 88(2), 103-10.
    • (2007) Int. J. Exp. Pathol. , vol.88 , Issue.2 , pp. 103-110
    • Wallace, W.A.H.1    Fitch, P.M.2    Simpson, J.A.3    Howie, S.E.M.4
  • 15
    • 0022379117 scopus 로고
    • Fine structural changes in cryptogenic alveolitis and asbestosis
    • Corrin, B.; Dewar, A.; Rodriguez-Roisin, R.; Turner-Warwick, M. Fine structural changes in cryptogenic alveolitis and asbestosis. J. Pathol., 1985, 147(2), 107-19.
    • (1985) J. Pathol. , vol.147 , Issue.2 , pp. 107-119
    • Corrin, B.1    Dewar, A.2    Rodriguez-Roisin, R.3    Turner-Warwick, M.4
  • 16
    • 0024822235 scopus 로고
    • An immunohistochemical study of architectural remodelling and connective tissue synthesis in pulmonary fibrosis
    • rd; Boldt, J.; King, T. E. Jr; Crouch, E.; Vartio, T.; McDonald, J. A. An immunohistochemical study of architectural remodelling and connective tissue synthesis in pulmonary fibrosis. Am. Rev. Respir. Dis.,1989, 140(6), 1693-703.
    • (1989) Am. Rev. Respir. Dis. , vol.140 , Issue.6 , pp. 1693-1703
    • Kuhn 3rd, C.1    Boldt, J.2    King Jr., T.E.3    Crouch, E.4    Vartio, T.5    McDonald, J.A.6
  • 17
    • 0026024210 scopus 로고
    • Idiopathic pulmonary fibrosis. A paradigm for lung injury and repair
    • McDonald, J. A. Idiopathic pulmonary fibrosis. A paradigm for lung injury and repair. Chest, 1991, 99(Suppl 3), 87S-93S.
    • (1991) Chest , vol.99 , Issue.SUPPL. 3
    • McDonald, J.A.1
  • 18
    • 33847364936 scopus 로고    scopus 로고
    • The role of CXC chemokines in pulmonary fibrosis
    • Strieter, R. M.; Gomperts, B. N.; Keane, M. P. The role of CXC chemokines in pulmonary fibrosis. J. Clin. Invest., 2007, 117(3), 549-56.
    • (2007) J. Clin. Invest. , vol.117 , Issue.3 , pp. 549-556
    • Strieter, R.M.1    Gomperts, B.N.2    Keane, M.P.3
  • 19
    • 28044447391 scopus 로고    scopus 로고
    • Pathogenesis and natural history of usual interstitial pneumonia: The whole story or the last chapter of a long novel
    • Strieter, R. M. Pathogenesis and natural history of usual interstitial pneumonia: the whole story or the last chapter of a long novel. Chest, 2005, 128(Suppl 5), 526S-532S.
    • (2005) Chest , vol.128 , Issue.SUPPL. 5
    • Strieter, R.M.1
  • 20
    • 0030800795 scopus 로고    scopus 로고
    • Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung
    • Sime, P. J.; Xing, Z.; Graham, F. L.; Csaky, K. G.; Gauldie, J. Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung. J. Clin. Invest., 1997, 100(4), 768-76.
    • (1997) J. Clin. Invest. , vol.100 , Issue.4 , pp. 768-776
    • Sime, P.J.1    Xing, Z.2    Graham, F.L.3    Csaky, K.G.4    Gauldie, J.5
  • 22
    • 17844384822 scopus 로고    scopus 로고
    • Induction of epithelialmesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: Potential role in idiopathic pulmonary fibrosis
    • Willis, B. C.; Liebler, J. M.; Luby-Phelps, K.; Nicolson, A. G.; Crandall, E. D.; du Bois, R. M.; Borok, Z. Induction of epithelialmesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis. Am. J. Pathol., 2005, 166(5), 1321-32.
    • (2005) Am. J. Pathol. , vol.166 , Issue.5 , pp. 1321-1332
    • Willis, B.C.1    Liebler, J.M.2    Luby-Phelps, K.3    Nicolson, A.G.4    Crandall, E.D.5    du Bois, R.M.6    Borok, Z.7
  • 23
    • 0442291674 scopus 로고    scopus 로고
    • The role of connective tissue growth factor, a multifunctional matricellular protein, in fibroblast biology
    • Leask, A.; Abraham, D. J. The role of connective tissue growth factor, a multifunctional matricellular protein, in fibroblast biology. Biochem. Cell Biol., 2003, 81(6), 355-63.
    • (2003) Biochem. Cell Biol. , vol.81 , Issue.6 , pp. 355-363
    • Leask, A.1    Abraham, D.J.2
  • 24
    • 2942682928 scopus 로고    scopus 로고
    • Regulation of PDGF and its receptors in fibrotic diseases
    • Bonner, J. C. Regulation of PDGF and its receptors in fibrotic diseases. Cytokine Growth Factor Rev., 2004, 15(4), 255-73.
    • (2004) Cytokine Growth Factor Rev. , vol.15 , Issue.4 , pp. 255-273
    • Bonner, J.C.1
  • 25
    • 1642333177 scopus 로고    scopus 로고
    • Protection from fluorescein isothiocyanate-induced fibrosis in IL-13-deficient, but not IL-4-deficient, mice results from impaired collagen synthesis
    • Kolodsick, J. E.; Toews, G. B.; Jakubzick, C.; Hogaboam, C.; Moore, T. A.; McKenzie, A.; Wilke, C. A.; Chrisman, C. J.; Moore, B. B. Protection from fluorescein isothiocyanate-induced fibrosis in IL-13-deficient, but not IL-4-deficient, mice results from impaired collagen synthesis. J. Immunol., 2004, 172(7), 4068-76.
    • (2004) J. Immunol. , vol.172 , Issue.7 , pp. 4068-4076
    • Kolodsick, J.E.1    Toews, G.B.2    Jakubzick, C.3    Hogaboam, C.4    Moore, T.A.5    McKenzie, A.6    Wilke, C.A.7    Chrisman, C.J.8    Moore, B.B.9
  • 26
    • 30044449492 scopus 로고    scopus 로고
    • IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis
    • Fichtner-Feigl, S.; Strober, W.; Kawakami, K.; Puri, R. K.; Kitani, A. IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis. Nat. Med., 2006, 12(1), 99-106.
    • (2006) Nat. Med. , vol.12 , Issue.1 , pp. 99-106
    • Fichtner-Feigl, S.1    Strober, W.2    Kawakami, K.3    Puri, R.K.4    Kitani, A.5
  • 27
    • 4344600287 scopus 로고    scopus 로고
    • Regulation of found in inflammatory zone 1 expression in bleomycin-induced lung fibrosis: Role of IL-4/IL-13 and mediation via STAT-6
    • Liu, T.; Jin, H.; Ullenbruch, M.; Hu, B.; Hashimoto, N.; Moore, B.; McKenzie, A.; Lukacs, N. W.; Phan, S. H. Regulation of found in inflammatory zone 1 expression in bleomycin-induced lung fibrosis: role of IL-4/IL-13 and mediation via STAT-6. J. Immunol., 2004, 173(5), 3425-31.
    • (2004) J. Immunol. , vol.173 , Issue.5 , pp. 3425-3431
    • Liu, T.1    Jin, H.2    Ullenbruch, M.3    Hu, B.4    Hashimoto, N.5    Moore, B.6    McKenzie, A.7    Lukacs, N.W.8    Phan, S.H.9
  • 29
    • 33744919279 scopus 로고    scopus 로고
    • Chemokine/cytokine cocktail in idiopathic pulmonary fibrosis
    • Agostini, C.; Gurrieri, C. Chemokine/cytokine cocktail in idiopathic pulmonary fibrosis. Proc. Am. Thorac. Soc., 2006, 3(4), 357-63.
    • (2006) Proc. Am. Thorac. Soc. , vol.3 , Issue.4 , pp. 357-363
    • Agostini, C.1    Gurrieri, C.2
  • 30
    • 0030014832 scopus 로고    scopus 로고
    • Costimulation of fibroblast collagen and transforming growth factor beta1 gene expression by monocyte chemoattractant protein-1 via specific receptors
    • Gharaee-Kermani, M.; Denholm, E. M.; Phan, S. H. Costimulation of fibroblast collagen and transforming growth factor beta1 gene expression by monocyte chemoattractant protein-1 via specific receptors. J. Biol. Chem., 1996, 271(30), 17779-84.
    • (1996) J. Biol. Chem. , vol.271 , Issue.30 , pp. 17779-17784
    • Gharaee-Kermani, M.1    Denholm, E.M.2    Phan, S.H.3
  • 31
    • 0032843121 scopus 로고    scopus 로고
    • Clinical significance of MCP-1 levels in BALF and serum of patients with interstitial lung diseases
    • Suga, M.; Iyonaga, K.; Ichiyasu, H.; Saita, N.; Yamasaki, H.; Ando, M. Clinical significance of MCP-1 levels in BALF and serum of patients with interstitial lung diseases. Eur. Respir. J., 1999, 14(2), 376-82.
    • (1999) Eur. Respir. J. , vol.14 , Issue.2 , pp. 376-382
    • Suga, M.1    Iyonaga, K.2    Ichiyasu, H.3    Saita, N.4    Yamasaki, H.5    Ando, M.6
  • 33
    • 33646481327 scopus 로고    scopus 로고
    • Cutting edge: Nonproliferating mature immune cells from a novel type of organized lymphoid structure in idiopathic pulmonary fibrosis
    • Marchal-Sommé, J.; Uzunhan, Y.; Marchand-Adam, S.; Valeyre, D.; Soumelis, V.; Crestani, B.; Soler, P. Cutting edge: nonproliferating mature immune cells from a novel type of organized lymphoid structure in idiopathic pulmonary fibrosis. J. Immunol., 2006, 176(10), 5735-9.
    • (2006) J. Immunol. , vol.176 , Issue.10 , pp. 5735-5739
    • Marchal-Sommé, J.1    Uzunhan, Y.2    Marchand-Adam, S.3    Valeyre, D.4    Soumelis, V.5    Crestani, B.6    Soler, P.7
  • 34
    • 33751167623 scopus 로고    scopus 로고
    • Thoracic lymph node enlargement in usual interstitial pneumonitis and nonspecific-interstitial pneumonitis: Prevalence, correlation with disease activity and temporal evolution
    • Attili, A. K.; Kazerooni, E. A.; Gross, B. H.; Flaherty, K. R.; Martinez, F. J. Thoracic lymph node enlargement in usual interstitial pneumonitis and nonspecific-interstitial pneumonitis: prevalence, correlation with disease activity and temporal evolution. J. Thorac. Imaging, 2006, 21(4), 288-92.
    • (2006) J. Thorac. Imaging. , vol.21 , Issue.4 , pp. 288-292
    • Attili, A.K.1    Kazerooni, E.A.2    Gross, B.H.3    Flaherty, K.R.4    Martinez, F.J.5
  • 36
    • 26244458018 scopus 로고    scopus 로고
    • TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT)
    • Kasai, H.; Allen, J. T.; Mason, R. M.; Kamimura, T.; Zhang, Z. TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT). Respir. Res., 2005, 6, 56.
    • (2005) Respir. Res. , vol.6 , pp. 56
    • Kasai, H.1    Allen, J.T.2    Mason, R.M.3    Kamimura, T.4    Zhang, Z.5
  • 37
    • 6344254484 scopus 로고    scopus 로고
    • TGF-β1 induces alveolar epithelial to mesenchymal transition in vitro
    • Yao, H. W.; Xie, Q. M.; Chen, J. Q.; Deng, Y. M.; Tang, H. F. TGF-β1 induces alveolar epithelial to mesenchymal transition in vitro. Life Sci., 2004, 76(1), 29-37.
    • (2004) Life Sci. , vol.76 , Issue.1 , pp. 29-37
    • Yao, H.W.1    Xie, Q.M.2    Chen, J.Q.3    Deng, Y.M.4    Tang, H.F.5
  • 39
    • 36348946221 scopus 로고    scopus 로고
    • Acute exacerbation of idiopathic pulmonary fibrosis
    • Hyzy, R.; Huang, S.; Myers, J.; Flaherty, K.; Martinez, F. Acute exacerbation of idiopathic pulmonary fibrosis. Chest, 2007, 132(5), 1652-8.
    • (2007) Chest , vol.132 , Issue.5 , pp. 1652-1658
    • Hyzy, R.1    Huang, S.2    Myers, J.3    Flaherty, K.4    Martinez, F.5
  • 40
    • 51549101867 scopus 로고    scopus 로고
    • On behalf of the British thoracic society interstitial lung disease guideline group. Interstitial lung disease guideline: The British thoracic society in collaboration with the thoracic society of Australia and New Zealand and the Irish thoracic society
    • Wells, A. U.; Hirani, N.; on behalf of the British Thoracic Society Interstitial Lung Disease Guideline Group. Interstitial lung disease guideline: the British Thoracic Society in collaboration with the Thoracic Society of Australia and New Zealand and the Irish Thoracic Society. Thorax, 2008, 63(Suppl 5), v1-v58.
    • (2008) Thorax , vol.63 , Issue.SUPPL. 5
    • Wells, A.U.1    Hirani, N.2
  • 41
    • 0019406754 scopus 로고
    • Bleomycin-induced pulmonary fibrosis. Effects of steroid on collagen metabolism
    • Phan, S. H.; Thrall, R. S.; Williams, C. Bleomycin-induced pulmonary fibrosis. Effects of steroid on collagen metabolism. Am. Rev. Respir. Res., 1981, 124(4), 438-4.
    • (1981) Am. Rev. Respir. Res. , vol.124 , Issue.4 , pp. 438-434
    • Phan, S.H.1    Thrall, R.S.2    Williams, C.3
  • 43
    • 0017343621 scopus 로고
    • Treatment of idiopathic fibrosing alveolitis. Therapeutic experiences with azathioprine-prednisolone and Dpenicllamine- prednisolone combination therapy Schweiz
    • Cegla, U. H. Treatment of idiopathic fibrosing alveolitis. Therapeutic experiences with azathioprine-prednisolone and Dpenicllamine- prednisolone combination therapy Schweiz. Med. Wochenschr., 1977, 107(6), 184-7.
    • (1977) Med. Wochenschr. , vol.107 , Issue.6 , pp. 184-187
    • Cegla, U.H.1
  • 44
    • 0026389762 scopus 로고
    • Azathioprine combined with prednisone in the treatment of idiopathic pulmonary fibrosis: A prospective double-blind, randomized, placebo-controlled trial
    • Raghu, G.; Depaso, W. J.; Cain, K.; Hammar, S. P.; Wetzel, C. E.; Dreis, D. F.; Hutchinson, J.; Pardee, N. E.; Winterbauer, R. H. Azathioprine combined with prednisone in the treatment of idiopathic pulmonary fibrosis: a prospective double-blind, randomized, placebo-controlled trial. Am. Rev. Respir. Dis., 1991, 144(2), 29l-6.
    • (1991) Am. Rev. Respir. Dis. , vol.144 , Issue.2
    • Raghu, G.1    Depaso, W.J.2    Cain, K.3    Hammar, S.P.4    Wetzel, C.E.5    Dreis, D.F.6    Hutchinson, J.7    Pardee, N.E.8    Winterbauer, R.H.9
  • 48
    • 0024547095 scopus 로고
    • Randomized controlled trial comparing prednisolone alone with cyclophosphamide and low dose prednisolone in combination in cryptogenic fibrosing alveolitis
    • Johnson, M. A.; Kwan, S.; Snell, N. J. C.; Nunn, A. I.; Darbyshire, J. H.; Turner-Warwick, M. Randomized controlled trial comparing prednisolone alone with cyclophosphamide and low dose prednisolone in combination in cryptogenic fibrosing alveolitis. Thorax, 1989, 44(4), 280-8.
    • (1989) Thorax , vol.44 , Issue.4 , pp. 280-288
    • Johnson, M.A.1    Kwan, S.2    Snell, N.J.C.3    Nunn, A.I.4    Darbyshire, J.H.5    Turner-Warwick, M.6
  • 49
    • 0034047115 scopus 로고    scopus 로고
    • Cyclophosphamide in the treatment of idiopathic pulmonary fibrosis: A prospective study in patients who failed to respond to corticosteroids
    • rd; Toews, G.; Kazerooni, E.; Flint, A.; Martinze, F. J. Cyclophosphamide in the treatment of idiopathic pulmonary fibrosis: a prospective study in patients who failed to respond to corticosteroids. Chest, 2000, 117(6), 1619-26.
    • (2000) Chest , vol.117 , Issue.6 , pp. 1619-1626
    • Zisman, D.1    Lynch 3rd, J.2    Toews, G.3    Kazerooni, E.4    Flint, A.5    Martinze, F.J.6
  • 50
    • 0026755988 scopus 로고
    • Use of intermittent, intravenous cyclophosphamide for idiopathic fibrosis
    • Baughman, R. P.; Lower, E. E. Use of intermittent, intravenous cyclophosphamide for idiopathic fibrosis. Chest, 1992, 102(4), 1090-4.
    • (1992) Chest , vol.102 , Issue.4 , pp. 1090-1094
    • Baughman, R.P.1    Lower, E.E.2
  • 52
    • 0021992008 scopus 로고
    • Adverse effects of cyclophosphamide in idiopathic pulmonary fibrosis
    • Eliasson, O.; Cole, S. R.; Degraff, A. C. Jr. Adverse effects of cyclophosphamide in idiopathic pulmonary fibrosis. Conn. Med., 1985, 49(5), 286-9.
    • (1985) Conn. Med. , vol.49 , Issue.5 , pp. 286-289
    • Eliasson, O.1    Cole, S.R.2    Degraff Jr., A.C.3
  • 53
    • 0027391080 scopus 로고
    • Outcome of subjects with idiopathic pulmonary fibrosis who fail corticosteroid therapy. Implications for further studies
    • Dayton, C. S.; Schwartz, D. A.; Helmers, R. A.; Pueringer, R. J.; Gilbert, S. R.; Merchant, R. K.; Hunninghake, G. W. Outcome of subjects with idiopathic pulmonary fibrosis who fail corticosteroid therapy. Implications for further studies. Chest, 1993, 103(1), 69-73.
    • (1993) Chest , vol.103 , Issue.1 , pp. 69-73
    • Dayton, C.S.1    Schwartz, D.A.2    Helmers, R.A.3    Pueringer, R.J.4    Gilbert, S.R.5    Merchant, R.K.6    Hunninghake, G.W.7
  • 54
    • 2942699911 scopus 로고    scopus 로고
    • Combined corticosteroid and cyclophosphamide therapy does not alter survival in idiopathic pulmonary fibrosis
    • Collard, H. R.; Ryu, J. H.; Douglas, W. W.; Schwarz, M. I.; Curran-Everett, D.; King, T. E. Jr; Brown, K. K. Combined corticosteroid and cyclophosphamide therapy does not alter survival in idiopathic pulmonary fibrosis. Chest, 2004, 125(6), 2169-74.
    • (2004) Chest , vol.125 , Issue.6 , pp. 2169-2174
    • Collard, H.R.1    Ryu, J.H.2    Douglas, W.W.3    Schwarz, M.I.4    Curran-Everett, D.5    King Jr., T.E.6    Brown, K.K.7
  • 56
    • 33748201695 scopus 로고    scopus 로고
    • Interstitial lung disease in rheumatoid arthritis: Recent advances
    • Kim, D. S. Interstitial lung disease in rheumatoid arthritis: recent advances. Curr. Opin. Pulm. Med., 2006, 12(5), 346-53.
    • (2006) Curr. Opin. Pulm. Med. , vol.12 , Issue.5 , pp. 346-353
    • Kim, D.S.1
  • 57
    • 4444231773 scopus 로고    scopus 로고
    • Interstitial lung disease induced by drugs and radiation
    • Camus, P.; Fanton, A.; Bonniaud, P.; Camus, C.; Foucher, P. Interstitial lung disease induced by drugs and radiation. Respiration, 2004, 71(4), 301-26.
    • (2004) Respiration , vol.71 , Issue.4 , pp. 301-326
    • Camus, P.1    Fanton, A.2    Bonniaud, P.3    Camus, C.4    Foucher, P.5
  • 58
    • 37849042263 scopus 로고    scopus 로고
    • Polymyositis and interstitial lung disease with a favourable response to corticosteroids and methotrexate
    • Hoyos, N.; Casanova, A.; Sánchez, S.; Valenzuela, C.; García, A.; Girón, R. M. Polymyositis and interstitial lung disease with a favourable response to corticosteroids and methotrexate. Arch. Bronconeumol., 2007, 43(11), 636-9.
    • (2007) Arch. Bronconeumol , vol.43 , Issue.11 , pp. 636-639
    • Hoyos, N.1    Casanova, A.2    Sánchez, S.3    Valenzuela, C.4    García, A.5    Girón, R.M.6
  • 60
    • 0026634329 scopus 로고
    • The protective effect of colchicine on bleomycin-induced pulmonary fibrosis in rats
    • Zhang, L.; Zhu, Y.; Luo, W. The protective effect of colchicine on bleomycin-induced pulmonary fibrosis in rats. Chin. Med. Sci. J., 1992, 7(1), 58-60.
    • (1992) Chin. Med. Sci. J. , vol.7 , Issue.1 , pp. 58-60
    • Zhang, L.1    Zhu, Y.2    Luo, W.3
  • 61
    • 0023848350 scopus 로고
    • Colchicine suppresses the release of fibroblast growth factors from alveolar macrophages in vitro. The basis of possible therapeutic approach to the fibrotic disorders
    • Rennard, S. I.; Bitterman, P. B.; Ozaki, T.; Rom, W. N.; Crystal, R. G. Colchicine suppresses the release of fibroblast growth factors from alveolar macrophages in vitro. The basis of possible therapeutic approach to the fibrotic disorders. Am. Rev. Respir. Dis., 1988, 137(1), 181-5.
    • (1988) Am. Rev. Respir. Dis. , vol.137 , Issue.1 , pp. 181-185
    • Rennard, S.I.1    Bitterman, P.B.2    Ozaki, T.3    Rom, W.N.4    Crystal, R.G.5
  • 62
    • 17944391083 scopus 로고    scopus 로고
    • Cochicine versus prednisone in the treatment of idiopathic pulmonary fibrosis. A randomized prospective study. Members of the Lung Study Group
    • Douglas, W. W.; Ryu, J. H.; Swensen, S. J.; Offord, K. P.; Schroeder, D. R.; Caron, G. M.; DeRemee, R. A. Cochicine versus prednisone in the treatment of idiopathic pulmonary fibrosis. A randomized prospective study. Members of the Lung Study Group. Am. J. Respir. Crit. Care Med., 1998, 158(1), 220-5.
    • (1998) Am. J. Respir. Crit. Care Med. , vol.158 , Issue.1 , pp. 220-225
    • Douglas, W.W.1    Ryu, J.H.2    Swensen, S.J.3    Offord, K.P.4    Schroeder, D.R.5    Caron, G.M.6    Deremee, R.A.7
  • 63
    • 0031842059 scopus 로고    scopus 로고
    • Cochicine, D-penicllamine, and prednisone in the treatment of idiopathic pulmonary fibrosis: A controlled clinical trial
    • Selman, M.; Carrillo, G.; Salas, J.; Padilla, R. P.; Pérez-Chavira, R.; Sansores, R.; Chapela, R. Cochicine, D-penicllamine, and prednisone in the treatment of idiopathic pulmonary fibrosis: a controlled clinical trial. Chest, 1998, 114(2), 507-12.
    • (1998) Chest , vol.114 , Issue.2 , pp. 507-512
    • Selman, M.1    Carrillo, G.2    Salas, J.3    Padilla, R.P.4    Pérez-Chavira, R.5    Sansores, R.6    Chapela, R.7
  • 64
    • 0034054908 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Impact of oxygen and cochicine, prednisone, or no therapy on survival
    • Douglas, W. W.; Ryu, J. H.; Schroeder, D. R. Idiopathic pulmonary fibrosis: Impact of oxygen and cochicine, prednisone, or no therapy on survival. Am. J. Respir. Crit. Care Med., 2000, 161(4), 1172-8.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , Issue.4 , pp. 1172-1178
    • Douglas, W.W.1    Ryu, J.H.2    Schroeder, D.R.3
  • 67
    • 0023263236 scopus 로고
    • Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis
    • Cantin, A. M.; North, S. L.; Fells, G. A.; Hubbard, R. C.; Crystal, R. G. Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis. J. Clin. Invest., 1987, 79(6), 1665-73.
    • (1987) J. Clin. Invest. , vol.79 , Issue.6 , pp. 1665-1673
    • Cantin, A.M.1    North, S.L.2    Fells, G.A.3    Hubbard, R.C.4    Crystal, R.G.5
  • 68
    • 0031840980 scopus 로고    scopus 로고
    • Role of transcription factors in inflammatory lung diseases
    • Rahman, I.; MacNee, W. Role of transcription factors in inflammatory lung diseases. Thorax, 1998, 53(7), 601-12.
    • (1998) Thorax , vol.53 , Issue.7 , pp. 601-612
    • Rahman, I.1    MacNee, W.2
  • 69
    • 0024578662 scopus 로고
    • Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis
    • Cantin, A. M.; Hubbard, R. C.; Crystal, R. G. Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis. Am. Rev. Respir. Dis., 1989, 139(2), 370-2.
    • (1989) Am. Rev. Respir. Dis. , vol.139 , Issue.2 , pp. 370-372
    • Cantin, A.M.1    Hubbard, R.C.2    Crystal, R.G.3
  • 70
    • 0028230612 scopus 로고
    • The effect of oral Nacetlycysteine on lung glutathione levels in idiopathic pulmonary fibrosis
    • Meyer, A.; Buhl, R.; Magnussen, H. The effect of oral Nacetlycysteine on lung glutathione levels in idiopathic pulmonary fibrosis. Eur. Respir. J., 1994, 7(3), 431-6.
    • (1994) Eur. Respir. J. , vol.7 , Issue.3 , pp. 431-436
    • Meyer, A.1    Buhl, R.2    Magnussen, H.3
  • 71
    • 0029093174 scopus 로고
    • Intravenous Nacetylcysteine and lung glutathione of patients with pulmonary fibrosis and normals
    • Meyer, A.; Buhl, R.; Kampf, S.; Magnussen, H. Intravenous Nacetylcysteine and lung glutathione of patients with pulmonary fibrosis and normals. Am. J. Respir. Crit. Care Med., 1995, 152(3), 1055-60.
    • (1995) Am. J. Respir. Crit. Care Med. , vol.152 , Issue.3 , pp. 1055-1060
    • Meyer, A.1    Buhl, R.2    Kampf, S.3    Magnussen, H.4
  • 72
    • 0031449645 scopus 로고    scopus 로고
    • Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis. Adjunctive therapy to maintance immunosuppression
    • Behr, J.; Maier, K.; Degenkolb, B.; Krombach, F.; Vogelmeier, C. Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis. Adjunctive therapy to maintance immunosuppression. Am. J. Respir. Crit. Care Med., 1997, 156(6), 1897-901.
    • (1997) Am. J. Respir. Crit. Care Med. , vol.156 , Issue.6 , pp. 1897-1901
    • Behr, J.1    Maier, K.2    Degenkolb, B.3    Krombach, F.4    Vogelmeier, C.5
  • 73
    • 0036014536 scopus 로고    scopus 로고
    • Intracellular glutathione and bronchoalveolar cells in fibrosing alveolitis: Effects of N-acetylcysteine
    • Behr, J.; Degenkolb, B.; Krombach, F.; Vogelmeier, C. Intracellular glutathione and bronchoalveolar cells in fibrosing alveolitis: effects of N-acetylcysteine. Eur. Respir. J., 2002, 19(5), 906-11.
    • (2002) Eur. Respir. J. , vol.19 , Issue.5 , pp. 906-911
    • Behr, J.1    Degenkolb, B.2    Krombach, F.3    Vogelmeier, C.4
  • 74
    • 0347357969 scopus 로고    scopus 로고
    • Glutathione regulates transforming growth factor-beta-stimulated collagen production in fibroblasts
    • Liu, R. M.; Liu, Y.; Forman, H. J.; Olman, M.; Tarpey, M. M. Glutathione regulates transforming growth factor-beta-stimulated collagen production in fibroblasts. Am. J. Physiol. Lung Cell. Mol. Physiol., 2004, 286(1), L121-L128.
    • (2004) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.286 , Issue.1
    • Liu, R.M.1    Liu, Y.2    Forman, H.J.3    Olman, M.4    Tarpey, M.M.5
  • 75
    • 0025875690 scopus 로고
    • Oral N-acetylcysteine reduces bleomycin-induced collagen deposition in the lungs of mice
    • Shahzeidi, S.; Sarnstrand, B.; Jeffery, P. K.; McAnulty, R. J.; Laurent, G. Oral N-acetylcysteine reduces bleomycin-induced collagen deposition in the lungs of mice. J. Eur. Respir. J., 1991, 4(7), 845-52.
    • (1991) J. Eur. Respir. J. , vol.4 , Issue.7 , pp. 845-852
    • Shahzeidi, S.1    Sarnstrand, B.2    Jeffery, P.K.3    McAnulty, R.J.4    Laurent, G.5
  • 79
    • 30744451720 scopus 로고    scopus 로고
    • Acute exacerbation of idiopathic pulmonary fibrosis: Frequency and clinical features
    • Kim, D. S.; Park, J. H.; Park, B. K.; Lee, J. S.; Nicholson, A. G.; Colby, T. Acute exacerbation of idiopathic pulmonary fibrosis: frequency and clinical features. Eur. Respir. J., 2006, 27(1), 143-50.
    • (2006) Eur. Respir. J. , vol.27 , Issue.1 , pp. 143-150
    • Kim, D.S.1    Park, J.H.2    Park, B.K.3    Lee, J.S.4    Nicholson, A.G.5    Colby, T.6
  • 80
    • 0027285888 scopus 로고
    • Acute exacerbation in idiopathic pulmonary fibrosis. Analysis of clinical and pathologic findings in three cases
    • Kondoh, Y.; Taniguchi, H.; Kawabata, Y.; Yokoi, T.; Suzuki, K.; Takag, K. Acute exacerbation in idiopathic pulmonary fibrosis. Analysis of clinical and pathologic findings in three cases. Chest, 1993, 103(6), 1808-12.
    • (1993) Chest , vol.103 , Issue.6 , pp. 1808-1812
    • Kondoh, Y.1    Taniguchi, H.2    Kawabata, Y.3    Yokoi, T.4    Suzuki, K.5    Takag, K.6
  • 81
    • 28144449401 scopus 로고    scopus 로고
    • Histopathologic features and outcome of patients with acute exacerbation of idiopathic pulmonary fibrosis undergoing surgical lung biopsy
    • Parambil, J. G.; Myers, J. L.; Ryu, J. H. Histopathologic features and outcome of patients with acute exacerbation of idiopathic pulmonary fibrosis undergoing surgical lung biopsy. Chest, 2005, 128(5), 3310-5.
    • (2005) Chest , vol.128 , Issue.5 , pp. 3310-3315
    • Parambil, J.G.1    Myers, J.L.2    Ryu, J.H.3
  • 82
    • 0031021273 scopus 로고    scopus 로고
    • CT findings during phase of accelerated deterioration in patients with idiopathic pulmonary fibrosis
    • Akira, M.; Hamada, H.; Sakatani, M.; Kobayashi, C.; Nishioka, M.; Yamamoto, S. CT findings during phase of accelerated deterioration in patients with idiopathic pulmonary fibrosis. Am. J. Roentgenol., 1997, 168(1), 79-83.
    • (1997) Am. J. Roentgenol. , vol.168 , Issue.1 , pp. 79-83
    • Akira, M.1    Hamada, H.2    Sakatani, M.3    Kobayashi, C.4    Nishioka, M.5    Yamamoto, S.6
  • 83
    • 0042171665 scopus 로고    scopus 로고
    • Cyclosporin A followed by the treatment of acute exacerbation of idiopathic pulmonary fibrosis with corticosteroid
    • Inase, N.; Sawada, M.; Ohtani, Y.; Isogai, S.; Sakashita, H.; Miyazaki, Y.; Yoshizawa, Y. Cyclosporin A followed by the treatment of acute exacerbation of idiopathic pulmonary fibrosis with corticosteroid. Intern. Med., 2003, 42(7), 565-70.
    • (2003) Intern. Med. , vol.42 , Issue.7 , pp. 565-570
    • Inase, N.1    Sawada, M.2    Ohtani, Y.3    Isogai, S.4    Sakashita, H.5    Miyazaki, Y.6    Yoshizawa, Y.7
  • 84
    • 43049123088 scopus 로고    scopus 로고
    • Acute exacerbation of idiopathic pulmonary fibrosis: A systematic review
    • Agarwal, R.; Jindal, S. K. Acute exacerbation of idiopathic pulmonary fibrosis: a systematic review. Eur. J. Intern. Med., 2008, 19(4), 227-35.
    • (2008) Eur. J. Intern. Med. , vol.19 , Issue.4 , pp. 227-235
    • Agarwal, R.1    Jindal, S.K.2
  • 86
    • 0029124143 scopus 로고
    • Molecular mechanisms of antifibrotic effect of interferon gamma in bleomycin-mouse model of lung fibrosis: Downregulation of TGF-beta and procollagen I and III gene expression
    • Gurujeyalakshmi, G.; Giri, S. N. Molecular mechanisms of antifibrotic effect of interferon gamma in bleomycin-mouse model of lung fibrosis: downregulation of TGF-beta and procollagen I and III gene expression. Exp. Lung Res., 1995, 21(5), 791-808.
    • (1995) Exp. Lung Res. , vol.21 , Issue.5 , pp. 791-808
    • Gurujeyalakshmi, G.1    Giri, S.N.2
  • 87
    • 0033592753 scopus 로고    scopus 로고
    • A preliminary study of long-term treatment with interferon gamma-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis
    • Ziesche, R.; Hofbauer, E.; Wittmann, K.; Petkov, V.; Block, L. H. A preliminary study of long-term treatment with interferon gamma-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis. N. Engl. J. Med., 1999, 314(17), 1264-9.
    • (1999) N. Engl. J. Med. , vol.314 , Issue.17 , pp. 1264-1269
    • Ziesche, R.1    Hofbauer, E.2    Wittmann, K.3    Petkov, V.4    Block, L.H.5
  • 88
    • 0345824715 scopus 로고    scopus 로고
    • Idiopathic Pulmonary Fibrosis Study Group. A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis
    • Raghu, G.; Brown, K. K.; Bradford, W. Z.; Starko, K.; Noble, P. W.; Schwartz, D. A.; King, T. E. Jr; Idiopathic Pulmonary Fibrosis Study Group. A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis. N. Engl. J. Med., 2004, 350(2), 125-33.
    • (2004) N. Engl. J. Med. , vol.350 , Issue.2 , pp. 125-133
    • Raghu, G.1    Brown, K.K.2    Bradford, W.Z.3    Starko, K.4    Noble, P.W.5    Schwartz, D.A.6    King Jr., T.E.7
  • 89
    • 67650349068 scopus 로고    scopus 로고
    • INSPIRE Study Group. Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): A multicentre, randomized, placebo-controlled trial
    • King, T. E. Jr; Albera, C.; Bradford, W. C.; Costabel, U.; Homer, P.; Lancster, L.; Noble, P. W.; Sahn, S. A.; Szwarcberg, J.; Thomeer, M.; Valeyre, D.; du Bois, R.; INSPIRE Study Group. Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): a multicentre, randomized, placebo-controlled trial. Lancet, 2009, 374(9685), 222-8.
    • (2009) Lancet , vol.374 , Issue.9685 , pp. 222-228
    • King Jr., T.E.1    Albera, C.2    Bradford, W.C.3    Costabel, U.4    Homer, P.5    Lancster, L.6    Noble, P.W.7    Sahn, S.A.8    Szwarcberg, J.9    Thomeer, M.10    Valeyre, D.11    du Bois, R.12
  • 92
    • 0142105888 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: The inflammation hypothesis revisited
    • Kamp, D. W. Idiopathic pulmonary fibrosis: the inflammation hypothesis revisited. Chest, 2003, 124(4), 1187-90.
    • (2003) Chest , vol.124 , Issue.4 , pp. 1187-1190
    • Kamp, D.W.1
  • 94
    • 0030958509 scopus 로고    scopus 로고
    • Tissue factor pathway inhibitor (TFPI) antigen plasma level in patients with interstitial lung disease before and after heparin administration
    • Cella, G.; Cipriani, A.; Tommasini, A.; Rampin, E.; Sbarai, A.; Rocconi, R.; Mazzaro, G.; Luzzatto, G. Tissue factor pathway inhibitor (TFPI) antigen plasma level in patients with interstitial lung disease before and after heparin administration. Semin. Thromb. Hemost., 1997, 23(1), 45-9.
    • (1997) Semin. Thromb. Hemost. , vol.23 , Issue.1 , pp. 45-49
    • Cella, G.1    Cipriani, A.2    Tommasini, A.3    Rampin, E.4    Sbarai, A.5    Rocconi, R.6    Mazzaro, G.7    Luzzatto, G.8
  • 95
    • 0025248164 scopus 로고
    • Clinical deterioration in patients with idiopathic pulmonary fibrosis: Causes and assessment
    • Panos, R. J.; Mortenson, R. L.; Niccoli, S. A.; King, T. E. Jr. Clinical deterioration in patients with idiopathic pulmonary fibrosis: causes and assessment. Am. J. Med., 1990, 88(4), 396-404.
    • (1990) Am. J. Med. , vol.88 , Issue.4 , pp. 396-404
    • Panos, R.J.1    Mortenson, R.L.2    Niccoli, S.A.3    King Jr., T.E.4
  • 96
    • 33745054936 scopus 로고    scopus 로고
    • Outcomes of patients with interstitial lung disease referred for lung transplant assessment
    • Reed, A.; Snell, G. I.; McLean, C.; Williams, T. J. Outcomes of patients with interstitial lung disease referred for lung transplant assessment. Intern. Med. J., 2006, 36(7), 423-30.
    • (2006) Intern. Med. J. , vol.36 , Issue.7 , pp. 423-430
    • Reed, A.1    Snell, G.I.2    McLean, C.3    Williams, T.J.4
  • 98
    • 0034004098 scopus 로고    scopus 로고
    • Pirfenidone inhibits NADPH-dependent microsomal lipid peroxidation and scavenges hydroxyl radicals
    • Misra, H. P.; Rabideau, C. Pirfenidone inhibits NADPH-dependent microsomal lipid peroxidation and scavenges hydroxyl radicals. Mol. Cell Biochem., 2000, 204(1-2), 119-26.
    • (2000) Mol. Cell Biochem. , vol.204 , Issue.1-2 , pp. 119-126
    • Misra, H.P.1    Rabideau, C.2
  • 99
    • 0001454995 scopus 로고
    • Pirfenidone: A novel pharmacologic agent for prevention and resolution (removal) of lung fibrosis
    • Margolin, S. B.; Lefkowitz, S. Pirfenidone: a novel pharmacologic agent for prevention and resolution (removal) of lung fibrosis. FASEB J., 1994, 8(4), A117.
    • (1994) FASEB J. , vol.8 , Issue.4
    • Margolin, S.B.1    Lefkowitz, S.2
  • 100
    • 0031557123 scopus 로고    scopus 로고
    • Pirfenidone diminishes cyclophosphamide-induced lung fibrosis in mice
    • Kehrer, J. B.; Margolin, S. B. Pirfenidone diminishes cyclophosphamide-induced lung fibrosis in mice. Toxicol. Lett., 1997, 90(2-3), 125-32.
    • (1997) Toxicol. Lett. , vol.90 , Issue.2-3 , pp. 125-132
    • Kehrer, J.B.1    Margolin, S.B.2
  • 101
    • 0030816833 scopus 로고    scopus 로고
    • Pirfenidone attenuates bleomycin-induced changes in pulmonary function in hamsters
    • Schelegle, E. S.; Mansoor, J. K.; Giri, S. Pirfenidone attenuates bleomycin-induced changes in pulmonary function in hamsters. Proc. Soc. Exp. Biol. Med., 1997, 216(3), 392-7.
    • (1997) Proc. Soc. Exp. Biol. Med. , vol.216 , Issue.3 , pp. 392-397
    • Schelegle, E.S.1    Mansoor, J.K.2    Giri, S.3
  • 102
    • 0032992019 scopus 로고    scopus 로고
    • Pirfenidone inhibits PDGF isoforms in bleomycin hamster model of lung fibrosis at the translational level
    • Gurujeyalakshmi, G.; Hollinger, M. A.; Giri, S. N. Pirfenidone inhibits PDGF isoforms in bleomycin hamster model of lung fibrosis at the translational level. Am. J. Physiol., 1999, 276(2), L311-L318.
    • (1999) Am. J. Physiol. , vol.276 , Issue.2
    • Gurujeyalakshmi, G.1    Hollinger, M.A.2    Giri, S.N.3
  • 103
    • 0032842405 scopus 로고    scopus 로고
    • Effects of pirfenidone on transforming growth factor-beta gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis
    • Iyer, S. N.; Gurujeyalakshmi, G.; Giri, S. N. Effects of pirfenidone on transforming growth factor-beta gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis. J. Pharmacol. Exp. Ther., 1999, 291(1), 367-73.
    • (1999) J. Pharmacol. Exp. Ther. , vol.291 , Issue.1 , pp. 367-373
    • Iyer, S.N.1    Gurujeyalakshmi, G.2    Giri, S.N.3
  • 105
    • 0033923129 scopus 로고    scopus 로고
    • Anti-inflammatory effect of pirfenidone in the bleomycin-hamster model of lung inflammation
    • Iyer, S. N.; Hyde, D. M.; Giri, S. N. Anti-inflammatory effect of pirfenidone in the bleomycin-hamster model of lung inflammation. Inflammation, 2000, 24(5), 477-91.
    • (2000) Inflammation , vol.24 , Issue.5 , pp. 477-491
    • Iyer, S.N.1    Hyde, D.M.2    Giri, S.N.3
  • 106
    • 0037141774 scopus 로고    scopus 로고
    • A novel anti-fibrotic agent pirfenidone suppresses tumor necrosis factor-alpha at the translational level
    • Nakazato, H.; Oku, H.; Yamane, S.; Tsuruta, Y.; Suzuki, R. A novel anti-fibrotic agent pirfenidone suppresses tumor necrosis factor-alpha at the translational level. Eur. J. Pharmacol., 2002, 446(1-3), 177-85.
    • (2002) Eur. J. Pharmacol. , vol.446 , Issue.1-3 , pp. 177-185
    • Nakazato, H.1    Oku, H.2    Yamane, S.3    Tsuruta, Y.4    Suzuki, R.5
  • 107
    • 0037141772 scopus 로고    scopus 로고
    • Pirfenidone suppresses tumor necrosis factor-alpha, enhances interleukin-10 and protects mice from endotoxic shock
    • Oku, H.; Nakazato, H.; Horikawa, T.; Tsuruta, Y.; Suzuki, R. Pirfenidone suppresses tumor necrosis factor-alpha, enhances interleukin-10 and protects mice from endotoxic shock. Eur. J. Pharmacol., 2002, 446(1-3), 167-76.
    • (2002) Eur. J. Pharmacol. , vol.446 , Issue.1-3 , pp. 167-176
    • Oku, H.1    Nakazato, H.2    Horikawa, T.3    Tsuruta, Y.4    Suzuki, R.5
  • 109
    • 0032926937 scopus 로고    scopus 로고
    • Treatment of idiopathic pulmonary fibrosis with a new antifibrotic agent, pirfenidone: Results of a prospective, open-label Phase II study
    • Raghu, G.; Johnson, W. C.; Lockhart, D.; Mageto, Y. Treatment of idiopathic pulmonary fibrosis with a new antifibrotic agent, pirfenidone: results of a prospective, open-label Phase II study. Am. J. Respir. Crit. Care Med., 1999, 159(4), 1061-9.
    • (1999) Am. J. Respir. Crit. Care Med. , vol.159 , Issue.4 , pp. 1061-1069
    • Raghu, G.1    Johnson, W.C.2    Lockhart, D.3    Mageto, Y.4
  • 110
    • 0036967820 scopus 로고    scopus 로고
    • Open-label compassionate use one year-treatment with pirfenidone to patients with chronic pulmonary fibrosis
    • Nagai, S.; Hamada, K.; Shigematsu, M.; Taniyama, M.; Yamauchi, S.; Izumi, T. Open-label compassionate use one year-treatment with pirfenidone to patients with chronic pulmonary fibrosis. Intern. Med., 2002, 41(12), 1118-23.
    • (2002) Intern. Med. , vol.41 , Issue.12 , pp. 1118-1123
    • Nagai, S.1    Hamada, K.2    Shigematsu, M.3    Taniyama, M.4    Yamauchi, S.5    Izumi, T.6
  • 113
    • 0029564275 scopus 로고
    • Endothelin-receptor antagonist bosentan prevents and reverses hypoxic pulmonary hypertension in rats
    • Chen, S. J.; Chen, Y. F.; Meng, Q. C.; Durand, J.; Dicarlo, V. S.; Oparil, S. Endothelin-receptor antagonist bosentan prevents and reverses hypoxic pulmonary hypertension in rats. J. Appl. Physiol., 1995, 79(6), 2122-31.
    • (1995) J. Appl. Physiol. , vol.79 , Issue.6 , pp. 2122-2131
    • Chen, S.J.1    Chen, Y.F.2    Meng, Q.C.3    Durand, J.4    Dicarlo, V.S.5    Oparil, S.6
  • 114
    • 0029951672 scopus 로고    scopus 로고
    • Endothelin-1 causes sequential trapping of platelets and neutrophils in pulmonary microcirculation in rats
    • Helset, E.; Lindal, S.; Olsen, R.; Myklebust, R.; Jorgensen, L. Endothelin-1 causes sequential trapping of platelets and neutrophils in pulmonary microcirculation in rats. Am. J. Physiol., 1996, 271(4), L538-L546.
    • (1996) Am. J. Physiol. , vol.271 , Issue.4
    • Helset, E.1    Lindal, S.2    Olsen, R.3    Myklebust, R.4    Jorgensen, L.5
  • 116
    • 0346888758 scopus 로고    scopus 로고
    • Effects of bosentan on cellular processes involved in pulmonary arterial hypertension: Do they explain the long-term benefit?
    • Clozel, M. Effects of bosentan on cellular processes involved in pulmonary arterial hypertension: do they explain the long-term benefit? Ann. Med., 2003, 35(8), 605-13.
    • (2003) Ann. Med. , vol.35 , Issue.8 , pp. 605-613
    • Clozel, M.1
  • 117
    • 0027213101 scopus 로고
    • Expression of endothelin-1 in the lungs of patients with cryptogenic fibrosing alveolitis
    • Giaid, A.; Michel, R. P.; Stewart, D. J.; Sheppard, M.; Corrin, B.; Hamid, Q. Expression of endothelin-1 in the lungs of patients with cryptogenic fibrosing alveolitis. Lancet, 1993, 341(8860), 1550-4.
    • (1993) Lancet , vol.341 , Issue.8860 , pp. 1550-1554
    • Giaid, A.1    Michel, R.P.2    Stewart, D.J.3    Sheppard, M.4    Corrin, B.5    Hamid, Q.6
  • 118
    • 0030755489 scopus 로고    scopus 로고
    • Increased endothelin-1 in bleomycin-induced pulmonary fibrosis and the effect of an endothelin receptor antagonist
    • Park, S. H.; Saleh, D.; Giaid, A.; Michel, R. P. Increased endothelin-1 in bleomycin-induced pulmonary fibrosis and the effect of an endothelin receptor antagonist. Am. J. Respir. Crit. Care Med., 1997, 156(2), 600-8.
    • (1997) Am. J. Respir. Crit. Care Med. , vol.156 , Issue.2 , pp. 600-608
    • Park, S.H.1    Saleh, D.2    Giaid, A.3    Michel, R.P.4
  • 120
    • 75149172006 scopus 로고    scopus 로고
    • Quality of life and dyspnoea in patients treated with bosentan for idiopathic pulmonary fibrosis (BUILD-1)
    • Raghu, G.; King, T. E. Jr; Behr, J.; Brown, K. K.; du Bois, R. M.; Leconte, I.; Roux, S.; Swigris, J. Quality of life and dyspnoea in patients treated with bosentan for idiopathic pulmonary fibrosis (BUILD-1). Eur. Respir. J., 2010, 35(1), 118-23.
    • (2010) Eur. Respir. J. , vol.35 , Issue.1 , pp. 118-123
    • Raghu, G.1    King Jr., T.E.2    Behr, J.3    Brown, K.K.4    du Bois, R.M.5    Leconte, I.6    Roux, S.7    Swigris, J.8
  • 121
    • 0027349638 scopus 로고
    • Cytokines involved in pulmonary fibrosis
    • Piguet, P. F. Cytokines involved in pulmonary fibrosis. Int. Rev. Exp. Pathol., 1993, 34(B), 173-81.
    • (1993) Int. Rev. Exp. Pathol. , vol.34 , Issue.B , pp. 173-181
    • Piguet, P.F.1
  • 122
    • 0028286946 scopus 로고
    • Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice
    • Piguet, P. F.; Vesin, C. Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice. Eur. Respir. J., 1994, 7(3), 515-8.
    • (1994) Eur. Respir. J. , vol.7 , Issue.3 , pp. 515-518
    • Piguet, P.F.1    Vesin, C.2
  • 123
    • 0346099102 scopus 로고    scopus 로고
    • Overexpression of tumor necrosis factor-alpha diminishes pulmonary fibrosis induced by bleomycin or transforming growth factor-beta
    • Fujita, M.; Shannon, J. M.; Morikawa, O.; Gauldi, J.; Hara, N.; Mason, R. J. Overexpression of tumor necrosis factor-alpha diminishes pulmonary fibrosis induced by bleomycin or transforming growth factor-beta. Am. J. Respir. Cell. Mol. Biol., 2003, 29(6), 669-76.
    • (2003) Am. J. Respir. Cell. Mol. Biol. , vol.29 , Issue.6 , pp. 669-676
    • Fujita, M.1    Shannon, J.M.2    Morikawa, O.3    Gauldi, J.4    Hara, N.5    Mason, R.J.6
  • 124
    • 0027724235 scopus 로고
    • Expression and localization of tumor necrosis factor-alpha and its mRNA in idiopathic pulmonary fibrosis
    • Piguet, P. F.; Ribaux, C.; Karpuz, V.; Grau, G. E.; Kapanci, Y. Expression and localization of tumor necrosis factor-alpha and its mRNA in idiopathic pulmonary fibrosis. Am. J. Pathol., 1993, 143(3), 651-5.
    • (1993) Am. J. Pathol. , vol.143 , Issue.3 , pp. 651-655
    • Piguet, P.F.1    Ribaux, C.2    Karpuz, V.3    Grau, G.E.4    Kapanci, Y.5
  • 125
    • 0028885803 scopus 로고
    • Cytoskeletal protein modulation in pulmonary alveolar myofibroblasts during idiopathic pulmonary fibrosis. Possible role of transforming growth factor beta and tumor necrosis factor alpha
    • Kapanci, Y.; Desmouliere, A.; Pache, J. C.; Redard, M.; Gabbiani, G. Cytoskeletal protein modulation in pulmonary alveolar myofibroblasts during idiopathic pulmonary fibrosis. Possible role of transforming growth factor beta and tumor necrosis factor alpha. Am. J. Respir. Crit. Care Med., 1995, 152(6), 2163-9.
    • (1995) Am. J. Respir. Crit. Care Med. , vol.152 , Issue.6 , pp. 2163-2169
    • Kapanci, Y.1    Desmouliere, A.2    Pache, J.C.3    Redard, M.4    Gabbiani, G.5
  • 127
    • 67651160533 scopus 로고    scopus 로고
    • MS80, a novel sulphated oligosaccharide, inhibits pulmonary fibrosis by targeting TGF-beta 1both in vitro and in vivo
    • Jiang, H. D.; Guang, H. S. MS80, a novel sulphated oligosaccharide, inhibits pulmonary fibrosis by targeting TGF-beta 1both in vitro and in vivo. Acta Pharmacol. Sin., 2009, 30(7), 973-9.
    • (2009) Acta Pharmacol. Sin. , vol.30 , Issue.7 , pp. 973-979
    • Jiang, H.D.1    Guang, H.S.2
  • 128
    • 0033862955 scopus 로고    scopus 로고
    • Abrogation of bleomycin-induced epithelial apoptosis and lung fibrosis by captopril or by caspase inhibitor
    • Wang, R.; Ibarra-Sunga, O.; Verlinski, L.; Pick, R.; Uhal, B. D. Abrogation of bleomycin-induced epithelial apoptosis and lung fibrosis by captopril or by caspase inhibitor. Am. J. Physiol. Lung Cell Mol. Physiol., 2000, 279(1), L143-L151.
    • (2000) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.279 , Issue.1
    • Wang, R.1    Ibarra-Sunga, O.2    Verlinski, L.3    Pick, R.4    Uhal, B.D.5
  • 129
    • 0021955760 scopus 로고
    • Monocrotaline-induced pulmonary fibrosis in rats: Amelioration by captopril and penicillamine
    • Molteni, A.; Ward, W. F.; Ts'ao, C. H.; Solliday, N. H.; Dunne, M. Monocrotaline-induced pulmonary fibrosis in rats: amelioration by captopril and penicillamine. Proc. Soc. Exp. Biol. Med., 1985, 180(1), 112-20.
    • (1985) Proc. Soc. Exp. Biol. Med. , vol.180 , Issue.1 , pp. 112-120
    • Molteni, A.1    Ward, W.F.2    Ts'ao, C.H.3    Solliday, N.H.4    Dunne, M.5
  • 130
    • 0034054128 scopus 로고    scopus 로고
    • Control of radiation-induced pneumopathy and lung fibrosis by angiotensinconverting enzyme inhibitors and an angiotensin II type 1 receptor blocker
    • Molteni, A.; Moulder, J. E.; Cohen, E. F.; Ward, W. F.; Fish, B. L.; Taylor, J. M.; Wolfe, L. F.; Brizio-Molteni, L.; Veno, P. Control of radiation-induced pneumopathy and lung fibrosis by angiotensinconverting enzyme inhibitors and an angiotensin II type 1 receptor blocker. Int. J. Radiat. Biol., 2000, 76(4), 523-32.
    • (2000) Int. J. Radiat. Biol. , vol.76 , Issue.4 , pp. 523-532
    • Molteni, A.1    Moulder, J.E.2    Cohen, E.F.3    Ward, W.F.4    Fish, B.L.5    Taylor, J.M.6    Wolfe, L.F.7    Brizio-Molteni, L.8    Veno, P.9
  • 131
    • 0344990166 scopus 로고    scopus 로고
    • Inhibition of amiodarone-induced lung fibrosis but not alveolitis by angiotensin system antagonists
    • Uhal, B. D.; Wang, R.; Laukka, J.; Zhuang, J.; Soledad-Conrad, V.; Filippatos, G. Inhibition of amiodarone-induced lung fibrosis but not alveolitis by angiotensin system antagonists. Pharmacol. Toxicol., 2003, 92(2), 81-7.
    • (2003) Pharmacol. Toxicol. , vol.92 , Issue.2 , pp. 81-87
    • Uhal, B.D.1    Wang, R.2    Laukka, J.3    Zhuang, J.4    Soledad-Conrad, V.5    Filippatos, G.6
  • 132
  • 134
    • 16444369634 scopus 로고    scopus 로고
    • Simvastatin inhibits growth factor expression and modulates profibrogenic markers in lung fibroblasts
    • Watts, K. L.; Sampson, E. M.; Schultz, G. S.; Spiteri, M. A. Simvastatin inhibits growth factor expression and modulates profibrogenic markers in lung fibroblasts. Am. J. Respir. Cell Mol. Biol., 2005, 32(4), 290-300.
    • (2005) Am. J. Respir. Cell Mol. Biol. , vol.32 , Issue.4 , pp. 290-300
    • Watts, K.L.1    Sampson, E.M.2    Schultz, G.S.3    Spiteri, M.A.4
  • 135
    • 4143091523 scopus 로고    scopus 로고
    • Impact of angiotensin-converting enzyme inhibitors and statins on survival in idiopathic pulmonary fibrosis
    • Nadrous, H. F.; Ryu, J. H.; Douglas, W. W.; Decker, P. A.; Olson, E. J. Impact of angiotensin-converting enzyme inhibitors and statins on survival in idiopathic pulmonary fibrosis. Chest, 2004, 126(2), 438-46.
    • (2004) Chest , vol.126 , Issue.2 , pp. 438-446
    • Nadrous, H.F.1    Ryu, J.H.2    Douglas, W.W.3    Decker, P.A.4    Olson, E.J.5
  • 136
    • 0028924146 scopus 로고    scopus 로고
    • Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have diminished capacity to synthesize prostagladin E2 and to express cyclooxygenase-2
    • Wilborn, J.; Bailie, M.; Coffey, M.; Burdick, M.; Strieter, R.; Peters-Golden, M. Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have diminished capacity to synthesize prostagladin E2 and to express cyclooxygenase-2. J. Clin. Invest., 1996, 95(4), 1861-8.
    • (1996) J. Clin. Invest. , vol.95 , Issue.4 , pp. 1861-1868
    • Wilborn, J.1    Bailie, M.2    Coffey, M.3    Burdick, M.4    Strieter, R.5    Peters-Golden, M.6
  • 139
    • 0022230283 scopus 로고
    • Thalidomide and congeners as anti-inflammatory agents
    • Koch, H. P. Thalidomide and congeners as anti-inflammatory agents. Prog. Med. Chem., 1985, 22, 165-242.
    • (1985) Prog. Med. Chem. , vol.22 , pp. 165-242
    • Koch, H.P.1
  • 140
    • 0026080801 scopus 로고
    • Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes
    • Sampaio, E. P.; Sarno, E. N.; Galilly, R.; Cohn, Z. A.; Kaplan, G. Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes. J. Exp. Med., 1991, 173(3), 699-703.
    • (1991) J. Exp. Med. , vol.173 , Issue.3 , pp. 699-703
    • Sampaio, E.P.1    Sarno, E.N.2    Galilly, R.3    Cohn, Z.A.4    Kaplan, G.5
  • 141
    • 0032100486 scopus 로고    scopus 로고
    • Thalidomide costimulates primary human T lymphocytes, preferentially inducing proliferation, cytokine production, and cytotoxic responses in the CD8+ subset
    • Haslett, P. A. J.; Corral, L. G.; Albert, M.; Kaplan, G. Thalidomide costimulates primary human T lymphocytes, preferentially inducing proliferation, cytokine production, and cytotoxic responses in the CD8+ subset. J. Exp. Med., 1998, 187(11), 1885-92.
    • (1998) J. Exp. Med. , vol.187 , Issue.11 , pp. 1885-1892
    • Haslett, P.A.J.1    Corral, L.G.2    Albert, M.3    Kaplan, G.4
  • 142
    • 0033168605 scopus 로고    scopus 로고
    • Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha
    • Corral, L. G.; Haslett, P. A.; Muller, G. W.; Chen, R.; Wong, L. M.; Ocampo, C. J.; Patterson, R. T.; Stirling, D. I.; Kaplan, G. Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha. J. Immunol., 1999, 163(1), 380-6.
    • (1999) J. Immunol. , vol.163 , Issue.1 , pp. 380-386
    • Corral, L.G.1    Haslett, P.A.2    Muller, G.W.3    Chen, R.4    Wong, L.M.5    Ocampo, C.J.6    Patterson, R.T.7    Stirling, D.I.8    Kaplan, G.9
  • 144
    • 33847402332 scopus 로고    scopus 로고
    • Thalidomide reduces IL-18, IL-8 and TNF-alpha release from alveolar macrophages in interstitial lung disease
    • Ye, Q.; Chen, B.; Tong, Z.; Nakamura, S.; Sarria, R.; Costabel, U.; Guzman, J. Thalidomide reduces IL-18, IL-8 and TNF-alpha release from alveolar macrophages in interstitial lung disease. Eur. Respir. J., 2006, 28(4), 824-31.
    • (2006) Eur. Respir. J. , vol.28 , Issue.4 , pp. 824-831
    • Ye, Q.1    Chen, B.2    Tong, Z.3    Nakamura, S.4    Sarria, R.5    Costabel, U.6    Guzman, J.7
  • 146
    • 49149123869 scopus 로고    scopus 로고
    • Thalidomide inhibits the intractable cough of idiopathic pulmonary fibrosis
    • Horton, M. R.; Danoff, S. K.; Lechtzin, N. Thalidomide inhibits the intractable cough of idiopathic pulmonary fibrosis. Thorax, 2008, 63(8), 749.
    • (2008) Thorax , vol.63 , Issue.8 , pp. 749
    • Horton, M.R.1    Danoff, S.K.2    Lechtzin, N.3
  • 149
    • 0034979153 scopus 로고    scopus 로고
    • Proteogylcans decorin and biglycan differentially modulate TGF-beta-mediated fibrotic response to bleomycin
    • Kolb, M.; Margetts, P. J.; Sime, P. J.; Gauldie, J. Proteogylcans decorin and biglycan differentially modulate TGF-beta-mediated fibrotic response to bleomycin. Am. J. Physiol. Lung Cell Mol. Physiol., 2001, 280(6), L1327-L1334.
    • (2001) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.280 , Issue.6
    • Kolb, M.1    Margetts, P.J.2    Sime, P.J.3    Gauldie, J.4
  • 150
    • 15244339164 scopus 로고    scopus 로고
    • Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycinmediated lung fibrosis
    • Daniels, C. E.; Wilkes, M. C.; Edens, M.; Kottom, T. J.; Murphy, S. J.; Limper, A. H.; Leof, E. B. Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycinmediated lung fibrosis. J. Clin. Invest., 2004, 114(9), 1308-16.
    • (2004) J. Clin. Invest. , vol.114 , Issue.9 , pp. 1308-1316
    • Daniels, C.E.1    Wilkes, M.C.2    Edens, M.3    Kottom, T.J.4    Murphy, S.J.5    Limper, A.H.6    Leof, E.B.7
  • 152
    • 77749324295 scopus 로고    scopus 로고
    • Imatinib-IpF Study Investigators. Imatinib treatment for idiopathic pulmonary fibrosis: Randomized placebocontrolled trial results
    • Daniels, C. E.; Lasky, J. A.; Limper, A. H.; Mieras, K.; Gabor, E.; Schoreder, D. R.; Imatinib-IpF Study Investigators. Imatinib treatment for idiopathic pulmonary fibrosis: randomized placebocontrolled trial results. Am. J. Respir. Crit. Care Med., 2009, 181(6), 604-10.
    • (2009) Am. J. Respir. Crit. Care Med. , vol.181 , Issue.6 , pp. 604-610
    • Daniels, C.E.1    Lasky, J.A.2    Limper, A.H.3    Mieras, K.4    Gabor, E.5    Schoreder, D.R.6
  • 157
    • 0029381341 scopus 로고
    • Effects of long term oxygen therapy in patients with idiopathic pulmonary fibrosis. I. Effect on the course of the primary disease and on pulmonary circulation
    • Polonski, L.; Krzywiecki, A.; Tendera, M.; Cwiertka, P.; Oklek, K.; Wodniecki, J. Effects of long term oxygen therapy in patients with idiopathic pulmonary fibrosis. I. Effect on the course of the primary disease and on pulmonary circulation. Pol. Arch. Med. Wewn., 1995, 94(4), 331-6.
    • (1995) Pol. Arch. Med. Wewn. , vol.94 , Issue.4 , pp. 331-336
    • Polonski, L.1    Krzywiecki, A.2    Tendera, M.3    Cwiertka, P.4    Oklek, K.5    Wodniecki, J.6
  • 159
    • 45149130397 scopus 로고    scopus 로고
    • Short term improvement in exercise capacity and symptoms following exercise training in interstitial lung disease
    • Holland, A. E.; Hill, C. J.; Conron, M.; Munro, P.; McDonald, C. F. Short term improvement in exercise capacity and symptoms following exercise training in interstitial lung disease. Thorax, 2008, 63(6), 549-54.
    • (2008) Thorax , vol.63 , Issue.6 , pp. 549-554
    • Holland, A.E.1    Hill, C.J.2    Conron, M.3    Munro, P.4    McDonald, C.F.5
  • 160
    • 68049092943 scopus 로고    scopus 로고
    • Outcomes of patients admitted to the intensive care unit with idiopathic pulmonary fibrosis
    • Rangappa, P.; Moran, J. L. Outcomes of patients admitted to the intensive care unit with idiopathic pulmonary fibrosis. Crit. Care Resusc., 2009, 11(2), 102-9.
    • (2009) Crit. Care Resusc. , vol.11 , Issue.2 , pp. 102-109
    • Rangappa, P.1    Moran, J.L.2
  • 166
    • 0035402360 scopus 로고    scopus 로고
    • Greater Manchester Pulmonary Fibrosis Consortium. Pulmonary function in idiopathic pulmonary fibrosis and referral for lung transplantation
    • Mogulkoc, N.; Brutsche, M. H.; Bishop, P. W.; Greaves, S. M.; Horrocks, A. W.; Egan, J. J.; Greater Manchester Pulmonary Fibrosis Consortium. Pulmonary function in idiopathic pulmonary fibrosis and referral for lung transplantation. Am. J. Respir. Crit. Care Med., 2001, 164(1), 103-8.
    • (2001) Am. J. Respir. Crit. Care Med. , vol.164 , Issue.1 , pp. 103-108
    • Mogulkoc, N.1    Brutsche, M.H.2    Bishop, P.W.3    Greaves, S.M.4    Horrocks, A.W.5    Egan, J.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.