Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide

Toxicology and Applied Pharmacology

Volumn 249, Issue 2, 2010, Pages 178-187

  Black, Adrienne T ^a   Hayden, Patrick J ^b   Casillas, Robert P ^c   Heck, Diane E ^d   Gerecke, Donald R ^a   Sinko, Patrick J ^a   Laskin, Debra L ^a   Laskin, Jeffrey D ^e  

^a RUTGERS UNIVERSITY   (United States)

^b MATTEK CORPORATION   (United States)

^c BATTELLE MEMORIAL INSTITUTE   (United States)

^d NEW YORK MEDICAL COLLEGE   (United States)

^e RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Eicosanoids; Skin; Sulfur mustard; Vesicant

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; BETA ACTIN; CYCLINE; CYCLOOXYGENASE 2; ETHYL 2 CHLOROETHYL SULFIDE; GLUTATHIONE TRANSFERASE A1; GLUTATHIONE TRANSFERASE A2; GLUTATHIONE TRANSFERASE A3; GLUTATHIONE TRANSFERASE A4; HISTONE H2AX; ICOSANOID; KERATIN; LEUKOTRIENE A4 HYDROLASE; LEUKOTRIENE C4 SYNTHASE; MESSENGER RNA; MUSTARD GAS DERIVATIVE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROSTAGLANDIN E SYNTHASE 1; UNCLASSIFIED DRUG;

ARTICLE; BLISTER; CELL NUCLEUS; CELL PROLIFERATION; CELL VACUOLE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; EXPOSURE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; KERATINOCYTE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SKIN; SKIN EDEMA; SKIN INFLAMMATION; STRATUM CORNEUM; THICKNESS; TIME;

BIOLOGICAL MARKERS; BLOTTING, WESTERN; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EICOSANOIDS; HISTONES; HUMANS; IRRITANTS; KERATINOCYTES; MUSTARD GAS; POLY ADENOSINE DIPHOSPHATE RIBOSE; PROLIFERATING CELL NUCLEAR ANTIGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN; TIME FACTORS;

BRASSICACEAE;

EID: 77958156277     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.09.005     Document Type: Article

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