Sulfur mustard-induced skin burns in weanling swine evaluated clinically and histopathologically

Journal of Applied Toxicology

Volumn 20, Issue SUPPL. 1, 2000, Pages

  Reid, F M ^a   Graham, J ^b   Niemuth, N A ^a   Singer, A W ^a   Janny, S J ^b   Johnson, J B ^a  

^a BATTELLE MEMORIAL INSTITUTE   (United States)

^b US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

Author keywords

Animal model; Chemical burns; Debride; Epidermal and dermal necrosis; Full thickness dermal bums; Sulfur mustard; Weanling swine

Indexed keywords

DERMATOLOGICAL AGENT; MUSTARD GAS;

ANIMAL; ARTICLE; BIOPSY; CHEMICAL BURN; CLASSIFICATION; EDEMA; FEMALE; HOSPITALIZATION; NECROSIS; PATHOLOGY; SWINE; WOUND HEALING;

ANIMALS; BIOPSY; BURNS, CHEMICAL; DERMATOLOGIC AGENTS; EDEMA; FEMALE; MUSTARD GAS; NECROSIS; SEVERITY OF ILLNESS INDEX; SWINE; WOUND HEALING;

EID: 0011823520     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1099-1263(200012)20:1+<::aid-jat673>3.0.co;2-o     Document Type: Article

References (21)

1. Ruhl CM, Park SJ, Danisal O, Morgan RF, Papirmeister B, Sidell FR, Edlich FR, Anthony LS, Himel HN. A serious skin sulfur mustard burn from an artillery shell. J. Emerg. Med. 1994; 12: 159-166.
2. Papirmeister B, Feister AJ, Robinson SI, Ford RD. Toxic mechanisms and pharmacological implications. In Medical Defense against Mustard Gas. CRC Press: Boston, 1991.
3. Kadivar H, Adams SC. Treatment of chemical and biological warfare injuries: insights derived from the 1984 Iraqi attack on Majnoon Island. Mil. Med. 1991; 156: 171-177.
4. Momeni AZ, Enshaeih S, Meghdadi M, Amidjavaheri M. Skin manifestations of mustard: a clinical study of 535 patients exposed to mustard gas. Arch. Dermatol. 1992; 128: 775-780.
5. Newman-Taylor AJ, Morris ARJ. Experience with mustard gas casualties [letter]. Lancet 1991; 337: 242.
6. Rees J, Harper P, Ellis F, Mitchell D. Mustard gas casualties [letter]. Lancet 1991; 337: 430.
7. Murray VSG, Volans GN. Management of injuries due to chemical weapons. Br. Med. J. 1991; 302: 129-130.
8. Borak J, Sidell FR. Agents of chemical warfare: sulfur mustard. Ann. Emerg. Med. 1992; 21: 303-308.
9. Eisenmenger W, Drasch G, Von Clarman M, Kretschmer E, Roider G. Clinical and morphological findings on mustard gas [bis(2-chloro-ethyl)sulfide] poisonings. J. Forens. Sci. 1991; 36: 1688-1698.
10. Barranco VP. Mustard gas and the dermatologists. Int. J. Dermatol. 1991; 30: 684-686.
11. Requena L, Requena C, Sanchez M, Jaqueti G, Aguilar A, Sanchez-Yus E, Hernandez-Moro B. Chemical warfare, cutaneous lesions from sulfur mustard gas. J. Am. Acad. Dermatol. 1988; 19: 529-536.
12. Marrs TC, Maynard RL, Sidell FR. Chemical Warfare Agents Toxicology and Treatment. Wiley: Chichester, 1996.
13. Meyer W, Schwarz R, Neurand K. Current Problems in Dermatology, vol. 7, Simon GA, Paster Z, Klingberg MA, Kaye M. (eds). Karger: Basel, 1978; 39-52.
14. Vogt RF, Dannenberg AM, Schofield BH, Hynes NA, Papirmeister B. Pathogenesis of skin lesions caused by sulfur mustard. Fundam. Appl. Toxicol. 1984; 4: S71-S83.
15. Mellor SG, Rice P, Cooper GJ. Vesicant burns. Br. J. Plast. Surg. 1991; 44: 434-437.
16. Requena L, Requena C, Sanchez M, Jaqueti G, Aguilar A, Sanchez-Yus E, Hernandez-Moro B. Chemical warfare. J. Am. Acad. Dermatol. 1988; 19: 529-536.
17. Somani SM, Babu SR. Toxicodynamics of sulfur mustard. Int. J. Clin. Pharmacol. Ther. Toxicol. 1989; 27: 419-435.
18. Renshaw B. Mechanisms in production of cutaneous injuries by sulfur and nitrogen mustards. In Chemical Warfare Agents, and Related Chemical Problems, DTIC No. AD-234 249. National Defense Research Committee: Washington, DC, 1946; 479-746.
19. Kamofsky DA, Graefand I. Smith HW. Studies on the mechanism of anion of the nitrogen and sulfur mustards in vivo. Am. J. Pathol. 1948; 24: 275-291.
20. Anslow WP, Houck CR. Systemic pharmacology of sulfur and nitrogen mustards. In Chemical Warfare Agents and Related Chemical Problems, DTIC No. AD-234 249. National Defense Research Committee: Washington DC, 1946; 440-478.
21. Graef I, Kamofsky DA, Jager VB, Krichesky B, Smith HW. The clinical and pathologic effects of the nitrogen and sulfur mustards in laboratory animals. Am. J. Pathol. 1948; 24: 1-47.