Histopathologic features seen with different animal models following cutaneous sulfur mustard exposure

Journal of Dermatological Science

Volumn 14, Issue 2, 1997, Pages 126-135

  Smith, Kathleen J ^a,c   Casillas, Robert ^a   Graham, John ^a   Skelton, Henry G ^b,d   Stemler, Fred ^a   Hackley Jr , Brennie E ^a  

^a U S ARMY   (United States)

^b ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

^c WALTER REED ARMY MEDICAL CENTER   (United States)

^d NONE   (United States)

Author keywords

animal models; bullae; sulfur mustard

Indexed keywords

MUSTARD GAS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; DRUG SCREENING; ENVIRONMENTAL EXPOSURE; GUINEA PIG; HISTOPATHOLOGY; NONHUMAN; NUDE MOUSE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; WOUND HEALING;

ANIMALS; BLISTER; DISEASE MODELS, ANIMAL; GUINEA PIGS; HUMANS; IRRITANTS; KERATINOCYTES; MALE; MICE; MICE, INBRED HRS; MICE, NUDE; MUSTARD GAS; SKIN; SPECIES SPECIFICITY; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 0031081132     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0923-1811(96)00560-9     Document Type: Article

References (27)

1. [1] Smith WJ, Dunn MA: Medical defense against blistering chemical warfare agents. Arch Dermatol 127: 1207-1213, 1991.
2. [2] Papirmeister B, Feister AJ, Robinson SI, Ford RD: Medical Defense Against Mustard Gas: Toxic Mechanisms and Pharmacological Implications. CRC Press, Inc. Boca Raton, Florida, 1991.
3. [3] Stein WH: Chemical reactions of sulfur and nitrogen mustard, in Chemical Warfare Agents, and Related Chemical Problems. Summary Technical Report of Division 9, National Defense Research Committee of the Office of Scientific Research and Development, Washington D.C. DTIC AD-234 249. 1946, pp. 389-478.
4. [4] Renshaw B: Mechanisms in production of cutaneous injuries by sulfur and nitrogen mustard, in Chemical Warfare Agents, and Related Chemical Problems. Summary Technical Report of Division 9, National Defense Research Committee of the Office of Scientific Research and Development, Washington D.C. DTIC AD-234 249. 1946, pp. 479-518.
5. [5] Karger, Basel, 1985. 3. Woodward DF, Nieves AL, Williams LS, Spada CS, Hawley, Duenes: A new hairless strain of guinea pig: Characterization of the cutaneous morphology and pharmacology in Models of Dermatology, Vol 4. Edited by HI Maibach, NJ Lowe. Kerger, Basel, 1989, pp. 71-78.
6. [6] Smith KJ, Graham JS, Moeller RB, Okerber CV, Skelton H, Hurst CG: Histopathologic features seen in sulfur mustard induced cutaneous lesions in the hairless guinea pig. J Cutan Pathol 22: 260-268, 1995.
7. [7] Smith KJ, Skelton HG, Hobson DW, Reid FM, Blank JA, Hurst CG: Cutaneous histopathologic features in weanling pigs after exposure to three different doses of liquid sulfur mustard. Am J Dermatopathol (accepted).
8. [8] Casillias RP, Smith KJ, Tezac-Reid TM, Castrejon LR, Stemler FW: Assessment of cutaneous sulfur mustard injury in the mouse ear edema model. Society of Toxicology Annual Meeting, 1996.
9. [9] Lavker RM, Dong G, Zheng P, Murphy GF: Hairless micropig skin: A novel model for studies of cutaneous biology. Am J Path 138: 687-697, 1991.
10. [10] Parenteau NL, Nolte CM, Bilbo P, Rosenberg M et al. Epidermis generated in vitro: Practical considerations and applications. J Cell Biochem 45: 245-251, 1991.
11. [11] Rosenthal DS. Shima TB, Celli G, DeLuca LM. Smulson ME: Engineered human skin model using poly(ADP-Ribose) polymerase antisense expression shows a reduced response to DNA damage. J Invest Dermatol 103: 38-43, 1995.
12. [12] Smith KJ, Graham JS, Skelton HG, O'Leary T, Moeller RB, Okerberg CV, Hurst CG: Evaluation of the cross-reacting anti-human antibodies in the euthymic hairless guinea pig model. Investigative Dermatology Meeting, May 1995.
13. [13] Bartek MJ, LaBudde JA, Maiback HI: Skin permeability in vivo: Comparison in rat, rabbit, pig, and man, J Invest Dermatol 58: 114-123, 1972.
14. [14] Dick IP, Scott RC: Pig ear skin as an in vitro model for human skin permeability. J Pharm Pharmacol 44: 640-645, 1992.
15. [15] Montagna W, Yun JS: The skin of the domestic pig. J Invest Dermatol 43-21, 1964.
16. [16] Meyer W, Gorgen S, Schlesinger C: Structural and histo-chemical aspects of epidermis development of fetal porcine skin. Am J Anat 176: 207-219, 1986.
17. [17] Monteiro-Riviere NA: Ultrastructural evaluation of the porcine integument, in Swine in Biomedical Research. Edited by ME Tumbleson. Plenum, New York, 1986, pp. 651-655.
18. [18] Rigal C, Pieraggi M-T, Vincent C, Prost C, Bouissou H, Serre G: Healing of full-thickness cutaneous wounds in the pig, I. Immunohistochemical study of epidermodermal junction regeneration. J Invest Dermatol 96: 777-785, 1991.
19. [19] Larjava H, Salo T, Haapasalmi K, Krammer RH, Heino J: Expression of integrins and basement membrane components by wound keratinocytes. J Clin Invest 92: 1425-1535, 1993.
20. [20] Gailit J, Welch MP, Clark RAF: TGF-betal stimulates expression of keratinocyte integrins during re-epithelialization of cutaneous wounds. J Invest Dermatol 103: 221-227, 1994.
21. [21] Patrick E, Maibach HI, Burkhalter A: Mechanisms of chemically induced skin irritation 1. Studies of time course, dose response, and components of inflammation in the laboratory mouse. Toxicol Appl Pharm 81: 476-490, 1985.
22. [22] Patrick E, Burkhalter A, Miabach HI: Recent investigations of mechanism of chemically induced skin irritaion in laboratory mice. J Invest Derm 88: 24s-31s. 1987.
23. [23] Wilmer JE, Burleson FG, Kayama F, Kanno J, Luster MI: Cytokine induction in human epidermal keratinocytes exposed to contact irritants and its relation to chemical-induced inflammation in mouse skin. J Invest Derm 102: 915-922, 1994.
24. [24] Henningsen GM: Dermal hypersensitivity: Immunologic principles and current methods of assessment, in Dermal and Ocular Toxicology. Edited by DW Hobson. CRC Press, Boca Raton, 1991, pp. 153-192.
25. [25] Mann SJ: Varieties of hairless-like mutant mice. J Invest Dermatol 56: 170-173. 1971.
26. [26] Montagna W, Chase HB, Melaragno H: The skin of hairless mice: The formation of cysts and the distribution of lipids. J Invest Dermatol 19: 83-94. 1981.
27. [27] Vessey DA, Lee K-H, Boyer TD: Differentiation-induced enhancement of the ability of cultured human keratinocytes to suppress oxidative stress. J Invest Dermatol 104: 355-358, 1995.