Immunochemical detection of sulfur mustard adducts with keratins in the stratum corneum of human skin

Chemical Research in Toxicology

Volumn 15, Issue 1, 2002, Pages 21-25

  Van der Schans, Govert P ^a   Noort, Daan ^a   Mars Groenendijk, Roos H ^a   Fidder, Alex ^a   Chau, Lai F ^a   De Jong, Leo P A ^a   Benschop, Hendrik P ^a  

^a TNO   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; GLUTAMINE; KERATIN; MONOCLONAL ANTIBODY; MUSTARD GAS;

ARTICLE; CHEMICAL WARFARE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; HUMAN; HUMAN TISSUE; IMMUNOCHEMISTRY; IMMUNOFLUORESCENCE MICROSCOPY; POLLUTANT; PROTEIN BINDING; QUANTITATIVE ASSAY; SKIN TEST; STRATUM CORNEUM;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPIDERMIS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HAPTENS; HUMANS; IMMUNOHISTOCHEMISTRY; KERATINS; MICE; MICROSCOPY, FLUORESCENCE; MUSTARD GAS;

EID: 0036153868     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0100136     Document Type: Article

References (23)

1. Urban terrorism-chemical warfare in Japan
2. Verification of exposure to sulfur mustard in two casualties of the Iran-Iraq conflict
3. New method for retrospective detection of exposure to organophosphate anticholinesterases: Application to alleged sarin victims of Japanese terrorists
4. Quantitative analysis of O-isopropyl methylphosphonic acid in serum samples of Japanese citizens allegedly exposed to sarin: Estimation of internal dosage
5. Immunochemical detection of adducts of sulfur mustard to DNA of calf thymus and human white blood cells
6. Monitoring of in vitro and in vivo exposure to sulfur mustard by GC/MS determination of the N-terminal valine adduct in hemoglobin after a modified Edman degradation
7. Alkylation of human serum albumin by sulfur mustard in vitro and in vivo: Mass spectrometric analysis of a cysteine adduct as a sensitive biomarker of exposure
8. Monoclonal antibodies to a benzo[a]pyrene diolepoxide modified protein
9. Immunoassays for proteins alkylated by nicotine-derived N-nitrosamines
10. Immunochemical detection of liver protein adducts of the nonsteroidal antiinflammatory drug diclofenac
11. Michael addition-type 4-hydroxy-2-nonenal adducts in modified low-density lipoproteins: Markers for atherosclerosis
12. Identification of a chemical marker of environmental exposure to formaldehyde
13. Measurement of hemoglobin-acetaldehyde adduct in alcoholic patients
14. An immunoassay for monitoring human exposure to ethylene oxide
15. 14C]sulfur mustard
16. Keratin filaments of cultured human epidermal cells
17. The expression of keratin genes in epidermis and cultured epidermal cells
18. Solid-phase synthesis of peptide haptens containing a cysteine-sulfur mustard adduct
19. Effects of nicotinamide on biochemical changes and microblistering induced by sulfur mustard in human skin organ cultures
20. The molecular biology of intermediate filament proteins
21. The keratinocyte cytoskeleton
22. Differential extraction of keratin subunits and filaments from normal human epidermis