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Volumn 16, Issue 1, 2010, Pages 114-124

Characterization of acute and long-term sulfur mustard-induced skin injuries in hairless guinea-pigs using non-invasive methods

Author keywords

Hairless guinea pig; MMP; Prostaglandin; Skin; Sulfur mustard

Indexed keywords

ANIMAL MODEL; ANTI-INFLAMMATORIES; AREA MEASUREMENT; BASAL CELLS; BASEMENT MEMBRANE; CLINICAL EVALUATION; CYTOTOXIC EFFECTS; HEALING PROCESS; HEALTH SYSTEMS; HISTOLOGICAL EVALUATION; INFLAMMATORY CELLS; LONG-TERM EFFECTS; METALLOPROTEINASE-9; MMP; NONINVASIVE METHODS; PIG MODEL; POST-EXPOSURE; SKIN EXPOSURE; SKIN INJURIES; SMALL ANIMAL MODEL; SULFUR MUSTARD; TIME DURATION; TRANSEPIDERMAL WATER LOSS;

EID: 73549101718     PISSN: 0909752X     EISSN: 16000846     Source Type: Journal    
DOI: 10.1111/j.1600-0846.2009.00409.x     Document Type: Article
Times cited : (26)

References (57)
  • 1
    • 0028905042 scopus 로고
    • Sulfur mustard: its continuing threat as a chemical warfare agent, the cutaneous lesions induced, progress in understanding its mechanism of action, its long-term health effects, and new developments for protection and therapy
    • Smith KJ, Hurst CG, Moeller RB, Skelton HG, Sidell FR. Sulfur mustard: its continuing threat as a chemical warfare agent, the cutaneous lesions induced, progress in understanding its mechanism of action, its long-term health effects, and new developments for protection and therapy. J Am Acad of Dermatol 1995, 32:765-776.
    • (1995) J Am Acad of Dermatol , vol.32 , pp. 765-776
    • Smith, K.J.1    Hurst, C.G.2    Moeller, R.B.3    Skelton, H.G.4    Sidell, F.R.5
  • 2
    • 20044373718 scopus 로고    scopus 로고
    • The pharmacology, toxicology, and medical treatment of sulphur mustard poisoning
    • Balali-Mood M, Hefazi M. The pharmacology, toxicology, and medical treatment of sulphur mustard poisoning. Fund Clin Pharmacol 2005, 19:297-315.
    • (2005) Fund Clin Pharmacol , vol.19 , pp. 297-315
    • Balali-Mood, M.1    Hefazi, M.2
  • 3
    • 0003301355 scopus 로고
    • Clinical management of mustard gas casualties
    • Willems JL. Clinical management of mustard gas casualties. Anna Med Militaris 1989, 3((Suppl.)):1-61.
    • (1989) Anna Med Militaris , vol.3 , Issue.SUPPL. , pp. 1-61
    • Willems, J.L.1
  • 4
    • 0000221874 scopus 로고
    • Disability produced by exposure of skin to mustard-gas vapour
    • Sinclair DC. Disability produced by exposure of skin to mustard-gas vapour. Br Med J 1950, 1:346-349.
    • (1950) Br Med J , vol.1 , pp. 346-349
    • Sinclair, D.C.1
  • 5
    • 0242415273 scopus 로고    scopus 로고
    • Incidence of lung, eye, and skin lesions as late complications in 34,000 Iranians with wartime exposure to mustard agent
    • Khateri S, Ghanei M, Keshavarz S, Soroush M, Haines D. Incidence of lung, eye, and skin lesions as late complications in 34,000 Iranians with wartime exposure to mustard agent. J Occup Environ Med 2003, 45:1136-1143.
    • (2003) J Occup Environ Med , vol.45 , pp. 1136-1143
    • Khateri, S.1    Ghanei, M.2    Keshavarz, S.3    Soroush, M.4    Haines, D.5
  • 7
    • 39049156333 scopus 로고    scopus 로고
    • Wound healing of cutaneous sulfur mustard injuries: strategies for the development of improved therapies
    • Graham JS, Chilcott RP, Rice P, Milner SM, Hurst CG, Maliner BI. Wound healing of cutaneous sulfur mustard injuries: strategies for the development of improved therapies. J Burns Wounds 2005, 4:e1-e45.
    • (2005) J Burns Wounds , vol.4
    • Graham, J.S.1    Chilcott, R.P.2    Rice, P.3    Milner, S.M.4    Hurst, C.G.5    Maliner, B.I.6
  • 8
    • 34547801292 scopus 로고    scopus 로고
    • Cetirizine, doxepine, and hydroxyzine in the treatment of pruritus due to sulfur mustard: a randomized clinical trial
    • Shohrati M, Davoudi SM, Keshavarz S, Sadr B, Tajik A. Cetirizine, doxepine, and hydroxyzine in the treatment of pruritus due to sulfur mustard: a randomized clinical trial. Cut Ocular Toxicol 2007, 26:249-255.
    • (2007) Cut Ocular Toxicol , vol.26 , pp. 249-255
    • Shohrati, M.1    Davoudi, S.M.2    Keshavarz, S.3    Sadr, B.4    Tajik, A.5
  • 9
    • 34249721652 scopus 로고    scopus 로고
    • Phenol and menthol in the treatment of chronic skin lesions following mustard gas exposure
    • Panahi Y, Davoodi SM, Khalill H, Dashti-Khavidaki S, Bigdeli M. Phenol and menthol in the treatment of chronic skin lesions following mustard gas exposure. Singapore Med J 2007, 48:392-395.
    • (2007) Singapore Med J , vol.48 , pp. 392-395
    • Panahi, Y.1    Davoodi, S.M.2    Khalill, H.3    Dashti-Khavidaki, S.4    Bigdeli, M.5
  • 13
    • 73549106847 scopus 로고    scopus 로고
    • Histopathologic features seen with different animal models following cutaneous sulfur mustard exposure
    • In, Maryland, USA, US Army Medical Research and Materiel Command
    • Smith KJ, Casillas RP, Graham J, Skelton HG, Stemler F, Hackley BE. Histopathologic features seen with different animal models following cutaneous sulfur mustard exposure. Proceedings of the 1996 Medical Defense Bioscience Review 1996, 1071-1077. In, Maryland, USA, US Army Medical Research and Materiel Command
    • (1996) Proceedings of the 1996 Medical Defense Bioscience Review , pp. 1071-1077
    • Smith, K.J.1    Casillas, R.P.2    Graham, J.3    Skelton, H.G.4    Stemler, F.5    Hackley, B.E.6
  • 14
    • 0030907518 scopus 로고    scopus 로고
    • A model for quantitative measurement of sulfur mustard skin lesions in the rabbit ear
    • Zlotogorski A, Goldenhersh M, Shafran A. A model for quantitative measurement of sulfur mustard skin lesions in the rabbit ear. Toxicology 1997, 120:105-110.
    • (1997) Toxicology , vol.120 , pp. 105-110
    • Zlotogorski, A.1    Goldenhersh, M.2    Shafran, A.3
  • 16
    • 0035997884 scopus 로고    scopus 로고
    • Potential anti-inflammatory treatments against cutaneous sulfur mustard injury using the mouse ear vesicant model
    • Dachir S, Fishbeine E, Meshulam Y, Sahar R, Amir A, Kadar T. Potential anti-inflammatory treatments against cutaneous sulfur mustard injury using the mouse ear vesicant model. Hum Exp Toxicol 2002, 21:197-203.
    • (2002) Hum Exp Toxicol , vol.21 , pp. 197-203
    • Dachir, S.1    Fishbeine, E.2    Meshulam, Y.3    Sahar, R.4    Amir, A.5    Kadar, T.6
  • 20
    • 0033839691 scopus 로고    scopus 로고
    • The pig as an experimental animal model of percutaneous permeation in man: qualitative and quantitative observations - an overview
    • Simon GA, Maiback HI. The pig as an experimental animal model of percutaneous permeation in man: qualitative and quantitative observations - an overview. Skin Pharmacol Appl Skin Physiol 2000, 13:229-234.
    • (2000) Skin Pharmacol Appl Skin Physiol , vol.13 , pp. 229-234
    • Simon, G.A.1    Maiback, H.I.2
  • 22
    • 0033764139 scopus 로고    scopus 로고
    • Hairless guinea pig skin: anatomical basis for studies of cutaneous biology
    • Sueki H, Gammal C, Kudoh K, Kligman AM. Hairless guinea pig skin: anatomical basis for studies of cutaneous biology. Eur J Dermatol 2000, 10:357-364.
    • (2000) Eur J Dermatol , vol.10 , pp. 357-364
    • Sueki, H.1    Gammal, C.2    Kudoh, K.3    Kligman, A.M.4
  • 23
    • 0942276892 scopus 로고    scopus 로고
    • Cutaneous toxicity of chemical irritants on hairless guinea pigs
    • Sueki H, Kligman AM. Cutaneous toxicity of chemical irritants on hairless guinea pigs. J Dermatol 2003, 30:859-870.
    • (2003) J Dermatol , vol.30 , pp. 859-870
    • Sueki, H.1    Kligman, A.M.2
  • 27
    • 0027355225 scopus 로고
    • Comparative morphology of sulfur mustard effects in the hairless guinea pig and a human skin equivalent
    • Petrali JP, Oglesby SB, Hamilton TA, Mills KR. Comparative morphology of sulfur mustard effects in the hairless guinea pig and a human skin equivalent. J Submicrosc Cytol Pathol 1993, 25:113-118.
    • (1993) J Submicrosc Cytol Pathol , vol.25 , pp. 113-118
    • Petrali, J.P.1    Oglesby, S.B.2    Hamilton, T.A.3    Mills, K.R.4
  • 29
    • 0033368124 scopus 로고    scopus 로고
    • Model for assessing efficacy of topical skin protectants against sulfur mustard vapor using hairless guinea pigs
    • Snider TH, Matthews MC, Braue EH Jr. Model for assessing efficacy of topical skin protectants against sulfur mustard vapor using hairless guinea pigs. J Appl Toxicol 1999, 19:S55-S58.
    • (1999) J Appl Toxicol , vol.19
    • Snider, T.H.1    Matthews, M.C.2    Braue, E.J.3
  • 31
    • 1842817583 scopus 로고    scopus 로고
    • Amelioration of sulfur mustard skin injury following a topical treatment with a mixture of a steroid and a NSAID
    • Dachir S, Fishbeine E, Meshulam Y, Sahar R, Chapman S, Amir A, Kadar T. Amelioration of sulfur mustard skin injury following a topical treatment with a mixture of a steroid and a NSAID. J Appl Toxicol 2004, 24:107-113.
    • (2004) J Appl Toxicol , vol.24 , pp. 107-113
    • Dachir, S.1    Fishbeine, E.2    Meshulam, Y.3    Sahar, R.4    Chapman, S.5    Amir, A.6    Kadar, T.7
  • 32
    • 0031106770 scopus 로고    scopus 로고
    • Evaluation of cross-reacting anti-human antibodies in the euthymic hairless guinea pig model (HGP) suggests that the HGP may be a model for the study of proliferative skin disease
    • Smith KJ, Graham JS, Skelton HG, O'Leary T, Moeller RB, Okerberg CV, Hurst CG. Evaluation of cross-reacting anti-human antibodies in the euthymic hairless guinea pig model (HGP) suggests that the HGP may be a model for the study of proliferative skin disease. J Dermatol Sci 1997, 14:240-250.
    • (1997) J Dermatol Sci , vol.14 , pp. 240-250
    • Smith, K.J.1    Graham, J.S.2    Skelton, H.G.3    O'Leary, T.4    Moeller, R.B.5    Okerberg, C.V.6    Hurst, C.G.7
  • 34
  • 35
    • 0030579099 scopus 로고    scopus 로고
    • Effects of calmodulin antagonists and anesthetics on the skin lesions induced by 2-chloroethylethyl sulfide
    • Kim YB, Hur GH, Choi DS, Shin S, Han BG, Lee YS, Sok DE. Effects of calmodulin antagonists and anesthetics on the skin lesions induced by 2-chloroethylethyl sulfide. Eur J Pharmacol 1996, 313:107-114.
    • (1996) Eur J Pharmacol , vol.313 , pp. 107-114
    • Kim, Y.B.1    Hur, G.H.2    Choi, D.S.3    Shin, S.4    Han, B.G.5    Lee, Y.S.6    Sok, D.E.7
  • 36
    • 0033845157 scopus 로고    scopus 로고
    • Domestic swine model for the assessment of chemical warfare agent-anesthetic interactions: some effects of sulfur mustard
    • Sawyer TW, Conley J, Hunter K, Lundy P, Hamilton M. Domestic swine model for the assessment of chemical warfare agent-anesthetic interactions: some effects of sulfur mustard. Mil Med 2000, 165:573-578.
    • (2000) Mil Med , vol.165 , pp. 573-578
    • Sawyer, T.W.1    Conley, J.2    Hunter, K.3    Lundy, P.4    Hamilton, M.5
  • 38
    • 7344266820 scopus 로고
    • Estimation of neutrophil infiltration into hairless guinea pig skin treated with 2,2′-dichlorodiethyl sulfide
    • In, Maryland, USA, US Army Medical Research and Materiel Command
    • Bongiovanni R, Millard CB, Schulz SM, Romano JM. Estimation of neutrophil infiltration into hairless guinea pig skin treated with 2,2′-dichlorodiethyl sulfide. Proceedings of the 1993 Medical Defense Bioscience Review 1993, 89-395. In, Maryland, USA, US Army Medical Research and Materiel Command
    • (1993) Proceedings of the 1993 Medical Defense Bioscience Review , pp. 89-395
    • Bongiovanni, R.1    Millard, C.B.2    Schulz, S.M.3    Romano, J.M.4
  • 42
    • 73549094276 scopus 로고    scopus 로고
    • Involvement of MMPs in ocular response to sulfur mustard in rabbits. Israel society for Vision & Eye Research, 27 Annual Meeting, Neve-Ilan 2007
    • Givant-Horwitz V, Dachir S, Cohen L, Yoav S, Gutman H, Cohen M, Fishbine E, Turetz J, Kadar T, Amir A. Involvement of MMPs in ocular response to sulfur mustard in rabbits. Israel society for Vision & Eye Research, 27 Annual Meeting, Neve-Ilan 2007
    • Givant-Horwitz, V.1    Dachir, S.2    Cohen, L.3    Yoav, S.4    Gutman, H.5    Cohen, M.6    Fishbine, E.7    Turetz, J.8    Kadar, T.9    Amir, A.10
  • 43
    • 73549116564 scopus 로고    scopus 로고
    • Involvement of matrix metalloproteinases in the cutaneous and ocular response to sulfur mustard
    • In, Maryland, USA, US Army Medical Research and Materiel Command, p. 155
    • Givant-Horwitz V, Amir A, Cohen L. Involvement of matrix metalloproteinases in the cutaneous and ocular response to sulfur mustard. Proceedings of the 2008 Medical Defense Bioscience Review 2008, In, Maryland, USA, US Army Medical Research and Materiel Command, p. 155
    • (2008) Proceedings of the 2008 Medical Defense Bioscience Review
    • Givant-Horwitz, V.1    Amir, A.2    Cohen, L.3    et al4
  • 44
    • 0036952731 scopus 로고    scopus 로고
    • Cytokine, chemokine, and matrix metalloproteinase response after sulfur mustard injury to weanling pig skin
    • Sabourin CK, Danne MM, Buxton KL, Casillas RP, Schlager JJ. Cytokine, chemokine, and matrix metalloproteinase response after sulfur mustard injury to weanling pig skin. J Biochem Mol Toxicol 2002, 16:263-272.
    • (2002) J Biochem Mol Toxicol , vol.16 , pp. 263-272
    • Sabourin, C.K.1    Danne, M.M.2    Buxton, K.L.3    Casillas, R.P.4    Schlager, J.J.5
  • 45
    • 33646826146 scopus 로고    scopus 로고
    • Preferential expression of matrix metalloproteinase-9 in mouse skin after sulfur mustard exposure
    • Shakarjian MP, Bhatt P, Gordon MK. Preferential expression of matrix metalloproteinase-9 in mouse skin after sulfur mustard exposure. J Appl Toxicol 2006, 26:239-246.
    • (2006) J Appl Toxicol , vol.26 , pp. 239-246
    • Shakarjian, M.P.1    Bhatt, P.2    Gordon, M.K.3    et al4
  • 46
    • 0035204586 scopus 로고    scopus 로고
    • Matrix metalloproteinases in skin pathology
    • Herouy Y. Matrix metalloproteinases in skin pathology. Int J Mol Med 2001, 7:3-12.
    • (2001) Int J Mol Med , vol.7 , pp. 3-12
    • Herouy, Y.1
  • 48
    • 0026339413 scopus 로고
    • Mustard gas and the dermatologist
    • Barranco VP. Mustard gas and the dermatologist. Int J Dermatol 1991, 30:684-686.
    • (1991) Int J Dermatol , vol.30 , pp. 684-686
    • Barranco, V.P.1
  • 49
    • 0027435058 scopus 로고
    • Putative roles of inflammation in the dermatopathology of sulfur mustard
    • Cowan FM, Broomfield CA. Putative roles of inflammation in the dermatopathology of sulfur mustard. Cell Biol Toxicol 1993, 9:201-213.
    • (1993) Cell Biol Toxicol , vol.9 , pp. 201-213
    • Cowan, F.M.1    Broomfield, C.A.2
  • 50
    • 0032923720 scopus 로고    scopus 로고
    • Response of normal human keratinocytes to sulfur mustard (HD): cytokine release using a non-enzymatic detachment procedure
    • Arroyo CM, Schafer RJ, Kurt EM, Broomfield CA, Carmichael AJ. Response of normal human keratinocytes to sulfur mustard (HD): cytokine release using a non-enzymatic detachment procedure. Hum Exp Toxicol 1999, 18:1-11.
    • (1999) Hum Exp Toxicol , vol.18 , pp. 1-11
    • Arroyo, C.M.1    Schafer, R.J.2    Kurt, E.M.3    Broomfield, C.A.4    Carmichael, A.J.5
  • 52
    • 0034567094 scopus 로고    scopus 로고
    • Alterations in inflammatory cytokine gene expression in sulfur mustard-exposed mouse skin
    • Sabourin CK, Petrali JP, Casillas RP. Alterations in inflammatory cytokine gene expression in sulfur mustard-exposed mouse skin. J Biochem Mol Toxicol 2000, 14:291-302.
    • (2000) J Biochem Mol Toxicol , vol.14 , pp. 291-302
    • Sabourin, C.K.1    Petrali, J.P.2    Casillas, R.P.3
  • 53
    • 0028948216 scopus 로고
    • Reduction of erythema in hairless guinea pigs after cutaneous sulfur mustard vapor exposure by pretreatment with niacinamide, promethazine and indomethacin
    • Yourick JJ, Dawson JS, Mitcheltree LW. Reduction of erythema in hairless guinea pigs after cutaneous sulfur mustard vapor exposure by pretreatment with niacinamide, promethazine and indomethacin. J Appl Toxicol 1995, 15:133-138.
    • (1995) J Appl Toxicol , vol.15 , pp. 133-138
    • Yourick, J.J.1    Dawson, J.S.2    Mitcheltree, L.W.3
  • 55
    • 0000698577 scopus 로고    scopus 로고
    • Systemic administration of candidate antivesicants to protect against topically applied sulfur mustard in the mouse ear vesicant model (MEMV)
    • Babin MC, Ricketts K, Skvorak JP, Gazaway M, Mitcheltree LW, Casillas RP. Systemic administration of candidate antivesicants to protect against topically applied sulfur mustard in the mouse ear vesicant model (MEMV). J Appl Toxicol 2000, 20:S141-S144.
    • (2000) J Appl Toxicol , vol.20
    • Babin, M.C.1    Ricketts, K.2    Skvorak, J.P.3    Gazaway, M.4    Mitcheltree, L.W.5    Casillas, R.P.6


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