Role of STAT3 in Ischemic Preconditioning

Journal of Molecular and Cellular Cardiology

Volumn 33, Issue 11, 2001, Pages 1929-1936

  Hattori, Reiji ^a,b,c   Maulik, Nilanjana ^a,b,c   Otani, Hajime ^a,b,c   Zhu, Li ^a,b,c   Cordis, Gerald ^a,b,c   Engelman, Richard M ^a,b,c   Siddiqui, M A Q ^a,b,c   Das, Dipak K ^a,b,c  

^a UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^b KANSAI MEDICAL UNIVERSITY   (Japan)

^c STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Apoptosis, Bcl 2. Bax; Ischemia reperfusion; JAK2; Precoditioning; STAT3

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; PROTEIN TYROSINE KINASE; STAT PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; STAT6 PROTEIN; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HEART FUNCTION; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; ISOLATED HEART; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

JANUS;

EID: 0035201264     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2001.1456     Document Type: Article

References (20)

1. JAK/STAT signaling is associated with cardiac dysfunction during ischemia and reperfusion
2. Cardioprotection with losartan is mediated through the inhibition of Janus kinase (JAK) signal transductors and activators of transcription (STAT) cascade
3. Angiotensin blockade inhibits SIF DNA binding activities via STAT3 after myocardial infarction
4. The type I angiotensin II receptor couples to Stat1 and Stat3 activation through Jak2 kinase in neonatal rat cardiac myocytes
5. Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway
6. Activation of JAK/STAT pathway transduces cytoprotective signal in rat acute myocardial infarction
7. Prevention of myeloma cell apoptosis by ectopic bcl-2 expression or interleukin 6-mediated up-regulation of bcl-XL
8. Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy
9. Inhibition of acute lymphoblastic leukemia by a Jak-2 inhibitor
10. Hypoxic preconditioning preserves antioxidant reserve in the working rat heart
11. Ischemic preconditioning reduces apoptosis by upregulating anti-death gene bcl-2
12. Ischemic preconditioning attenuates apoptotic cell death associated with ischemia/reperfusion
13. Regulation of cardiomyocyte apoptosis by redox-sensitive transcription factors
14. Differential regulation of bcl2-, AP-1 and NFkB on cardiomyocyte apoptosis during myocardial ischemic stress adaptation
15. Ischemic stress adaptation of heart triggers a tyrosine kinase regulated signaling pathway: A potential role for MAPKAP kinase 2
16. SAPKs regulation of ischemic preconditioning
17. The role of Jak/STAT signaling in heart tissue renin-angiotensin system
18. STATs: Signal transducers and activators of transcription
19. Myocardial ischemia activates the JAK-STAT pathway through angiotensin II signaling in in vivo myocardium of rats
20. Signal transduction and activator of transcription (STAT) protein-dependent activation of angiotensinogen promoter: A cellular signal for hypertrophy in cardiac muscle