Role of angiotensin II in activation of the JAK/STAT pathway induced by acute pressure overload in the rat heart

Circulation Research

Volumn 81, Issue 4, 1997, Pages 611-617

  Pan, Jing ^a   Fukuda, Keiichi ^a,b   Kodama, Hiroaki ^a   Makino, Shinji ^a   Takahashi, Toshiyuki ^a   Sano, Motoaki ^a   Hori, Shingo ^b   Ogawa, Satoshi ^a  

^a Cardiopulmonary Division   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

Angiotensin II; JAK STAT pathway; Myocardial hypertrophy; Pressure overload; Signal transduction

Indexed keywords

4' [(2 CYCLOPROPYL 7 METHYL 3H IMIDAZO[4,5 B]PYRIDIN 3 YL)METHYL][1,1' BIPHENYL] 2 CARBOXYLIC ACID; ALPHA INTERFERON; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; CILAZAPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GAMMA INTERFERON; UNCLASSIFIED DRUG;

ABDOMINAL AORTA; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; HEART HYPERTROPHY; HEART VENTRICLE OVERLOAD; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR BINDING; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SIGNAL TRANSDUCTION;

EID: 0030765570     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.81.4.611     Document Type: Article

References (60)

1. Zak R. Factors controlling cardiac growth. In Zak R, ed. Growth of the Heart in Health and Disease. New York, NY: Raven Press Publishers; 1984:165-185.
2. Levy D, Garrison RJ, Savage DD, Kannel WB. Castelli WP. Prognostic implicaations of echocardiographically determined left ventricular mass in the Framingham heart study. N Engl J Med. 1990;322:1561-1566.
3. Casale PN, Devereux RB, Milner M, Zullo G, Harshfield GA, Pickering TG, Laragh JH. Value of echocardiographic measurement of left ventricular mass in predicting cardiovascular morbid events in hypertensive men. Ann Intern Med. 1986;105:173-178.
4. Mann DL, Kent RL, Cooper G IV. Load regulation of the properties of adult feline cardiocytes: growth induction by cellular deformation. Circ Res. 1989;64:1079-1090.
5. Komuro I, Kaida T, Shibazaki Y, Kurabayashi M, Katoh Y, Hoh E, Takaku F, Yazaki Y. Stretching cardiac myocytes stimulates protooncogene expression. J Biol Chem. 1990;265:3595-3598.
6. Sadoshima J, Jahn L, Takahashi T, Kulik TJ, Izumo S. Molecular characterization of the stretch-induced adaptation of cultured cardiac cells: an in vitro model of load-induced cardiac hypertrophy. J Biol Chem. 1992;267:10551-10560.
7. Rozich JD, Barnes MA, Schmid PG, Zile MR, McDermott PJ, Cooper G IV. Load effects on gene expression during cardiac hypertrophy. J Mol Cell Cardiol. 1995;27:485-499.
8. Baker KM, Chernin MI, Wixson SK, Aceto JF. Renin-angiotensin system involvement in pressure-overload cardiac hypertrophy in rat. Am J Physiol. 1990;259:H324-H332.
9. Schunkert H, Sadoshima J, Cornelius T, Kagaya Y, Weinberg EO, Izumo S, Riegger G, Lorell BH.Angiotensin II-induced growth responses in isolated adult rat hearts: evidence for load-independent induction of cardiac protein synthesis by angiotensin II. Circ Res. 1995;76:489-497.
10. i, receptor subtype. Circ Res. 1993;73:413-423.
11. Yamazaki T, Komuro I, Kudoh S, Zou Y, Shiojima I, Hiro Y, Mizuno T, Maemura K, Kurihara H, Aikawa R, Takano H, Yazaki Y. Endothelin-1 is invohed in mechanical stress-induced cardiomyocyte hypertrophy. J Biol Chem. 1996;271:3221-3228.
12. Ichikawa KI, Hidai C, Okuda C, Kimata SI, Matsuoka R, Hosoda S, Quertermous T, Kawana M. Endogenous endothelin-1 mediates cardiac hypertrophy and switching of myosin heavy chain gene expression in rat ventricular myocardium. J Am Coll Cardiol 1996;27:1286-1291.
13. Zimmer HG, Kolbeck-Ruhmkorff C, Zierhut W. Cardiac hypertrophy induced by alpha- and beta-adrenergic receptor stimulation. Cardioscience. 1995;6:47-57.
14. Yamazaki T, Komuro I, Zou Y, Kudoh S, Shiojima I, Hire Y, Mizzen T, Awake R, Taken H, Yazaki Y. Norepinephrine induces the raf-1 kinase/mitogen-activated protein kinase cascade through both alpha 1- and beta- adrenoceptors. Circulation. 1997;95:1260-1268.
15. Takahashi N.,Calderone A, Izzo NJ, Maki TM, Marsh JD, Colucci WS. Hypertrophic stimuli induce transforming growth factor β1 expression in rat ventricular myocytes. J Clin Invest. 1994;94:1470-1476.
16. Hanson MC, Fath KA. Alexander RW, Delafontaine P. Induction of cardiac insulin-like growth factor I gene expression in pressure overload hypertrophy. Am J Med Sci 1993;306:69-74.
17. Friberg P, Isgaard J, Wahlander H, Wickman A, Guron G, Adams MA. Cardiac hypertrophy and related growth processes: the role of insulin-like growth factor-I. Blood Press Suppl. 1995;2:22-29.
18. Lorell BH. Cardiac renin-angiotensin system: role in development of pressure-overload hypertrophy. Can J Cardiol. 1995;11(suppl F):7-12.
19. Iwai N, Shimoike H, Kinoshita M. Cardiac renin-angiotensin system in the hypertrophied heart. Circulation. 1995;92:2690-2696.
20. Kaye DM, Kelly RA, Smith TW. Cytokines and cardiac hypertrophy: roles of angiotensin II and basic fibroblast growth factor. Clin Exp Pharmacol Physiol. 1996;suppl 3:s136-s141.
21. Lindpainter K, Ganten D. The cardiac renin-angiotensin system: an appraisal of present experimental and clinical evidence. Circ Res. 1991;68:905-921.
22. Iwai N, Shimoike H, Kinoshita M. Cardiac renin-angiotensin system in the hypertrophied heart. Circulation. 1995;92:2690-2696.
23. Kromer EP, Riegger GAJ. Effects of long-term angiotensin converting enzyme inhibition on myocardial hypertrophy in experimental aortic stenosis in the rat. Am J Cardiol. 1988;62:161-163.
24. Garavaglia GE, Messeri FH, Nunez BD, Schmieder RE, Frohlich ED. Immediate and short-term cardiovascular effects of a new converting enzyme inhibitor (lisinopril) in essential hypertension. Am J Cardiol. 1988;62:912-916.
25. Abraham G, Pogatsa-Murray G, Forster T, Csanady M, Sonkodi S. Effect of cilazapril in patients with essential hypertension: effect on cardiac hypertrophy. Orv Hetil. 1996;137:1583-15586.
26. RockmanHA, Wachhorst SP, Mao L, Ross J Jr. Ang II receptor blockade prevents ventricular hypertrophy and ANF gene expression with pressure overload in mice. Am J Physiol. 1994;266: H2468-H2475.
27. Bruckschlegel G, Holmer SR, Jundeleit K, Grimm D, Mutters F, Kromer EP, Riegger GA, Schunkert H. Blockade of the renin-angiotensin system in cardiac pressure-overload hypertrophy in rats. Hypertension. 1995;25:250-259.
28. Sadoshima J, Xu Y, Henry S, Slayter HS, Izumo S. Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell.1993;75:977-984.
29. Miyata S, Hander T, Osaka J, Kikuchi K. Renin-angiotensin system in stretch-induced hypertrophy of cultured neonatal rat heart cells. Eur J Pharmacol. 1996;307:81-88.
30. Sadoshima J, Izumo S. Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine/paracrine mechanism. EMBO J. 1993;12:1681-1692.
31. 2+-dependent signaling. Circ Res. 1995;76:1-15.
32. Sadoshima J, Izumo S. The heterotrimeric Gq protein-coupled angiotensin II receptor activates p21 ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytes. EMBO J. 1996;15:775-787.
33. Schiefer B, Paxlon WG, Chai Q, Marrero MB, Bernstein KE. Angiotensin II controls p2lras activity via p60-src. J Biol Chem. 1996;271:10329-10333.
34. Darnell JE Jr, Kerr IM, Stark GR, Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science. 1994;264:1415-1421.
35. Ihle JN, Kerr IM. Jaks and Stats in signaling by the cytokine receptor superfamily. Trends Genet. 1995;11:69-74.
36. Schindler C, Darnell JE. Transcriptional responses to polypeptide ligands: the JAK/STAT pathway. Annu Rev Biochem. 1995;64:621-651.
37. Ihle JN. Cytokine receptor signaling. Nature. 1995;377:591-594.
38. Ivashkiiv LB. Cytokines and STATs: how can signals achieve specificity? Immunity. 1995;3:1-4.
39. Ihle JN. STATs: signal transducers and activators of transcription. Cell. 1996;84:331-334.
40. Vignais ML, Sasowski HB, Watling D, Rogers NC, Gilman M. Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins. Mol Cell Biol. 1996;16:1759-1769.
41. Horvath CM, Darnell JE. The state of the STATs: recent developments in the study of signal transduction to the nucleus. Curr Opin Cell Biol. 1997;9:233-239.
42. Marrero MB, Schieffer B, Paxton WG, Heerdt L, Berk BC, Delafontaine P, Bernstein KE. Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor. Nature. 1995;375:247-250.
43. Marrero MB, Paxton WG, Schieffer B, Ling BN, Bernstein KE. Angiotensin II signaling events mediated by tyrosine phosphorylation. Cell Signal. 1996;8:21-26.
44. Schieffer B, Paxton WG, Marrero MB, Bernstein KE. Importance of tyrosine phosphorylation in angiotensin II type 1 receptor signaling. Hypertension. 1996;27:476-480.
45. Kodama Pan J, Makino S, Baba A, Hori S, Fukuda K. Angiotensin II directly stimulates the JAK/STAT pathway through AT-1 receptor in rat cardiomyocytes. Circulation, 1996;94(suppl I):I-405. Abstract.
46. Clozel JP, Kuhn H, Hefti F. Effects of chronic ACE inhibition on cardiac hypertrophy and coronary vascular reserve in spontaneously hypertensive rats with developed hypertension. J Hypertens. 1989;7:267-275.
47. Okunishi H, Song K, Oka Y, Kobayashi T, Kawamoto T, Ishihara H, Mori N, Miyazaki M. In vitro pharmacology of a novel nonpeptide angiotensin II-reccptor antagonist. E4177. Jpn J Pharmacol. 1993;62:239-244.
48. Dignam JD, Lebovitz RM, Roeder RG. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 1983;11:1475-1489.
49. Silvennoinen O, Schindler C, Schlessinger J, Levy DE. Ras-independent growth factor signaling by transcription factor tyrosine phosphorylation. Science. 1993;261:1736-1739.
50. Sadowski HB, Shuai K, Darnell JE Jr, Gilman MZ. A common nuclear signal transduction pathway activated by growth factor cytokine receptor. Science. 1993;261:1739-1744.
51. Strehlow I, Decker T. Transcriptional induction of IFN-gamma-responsive genes is modulated by DNA surrounding the Interferon stimulation response element. Nucleic Acids Res. 1992;20:3865-3872.
52. Decker T, Lew DJ, Mirkovitch J, Darnell JE Jr. Cytoplasm activation of GAF, an IFN-γ regulated DNA-binding factor. EMBO J. 1991;10:927-932.
53. Bluyssen HAR, Durbin JE, Levy DE. ISGF3gp48, a specificity switch for interferon activated transcription factors. Cytokine Growth Factor Rev. 1996;7:11-17.
54. Bhat GJ, Thekkumukara TJ, Thomas WG, Conrad KM, Baker KM. Angiotensin II stimulates sis-inducible factor-like DNA binding activity. J Biol Chem. 1994;269:31443-31449.
55. Bhat GJ, Thekkumukara TJ, Thomas WG, Conrad KM, Baker KM. Activation of the STAT pathway by angiotensin II in T3CHO/AT1A cells: cross-talk between angiotensin II and interleukin-6 nuclear signaling. J Biol Chem. 1995;270:19059-19065.
56. Kodama H, Fukuda K, Pan J, Makino S, Baba A, Hori S, Oguwa S. Leukemia inhibitory factor, a potent cardiac hypertrophic cytokine, activates the JAK/STAT pathway in rat cardiomyocytes. Circ.Res. In press.
57. Kunisada K, Hirota H, Fujio Y, Matsui H, Tani Y, Takihara KY, Kishimoto T. Activation of JAK-STAT and MAP kinases by leukemia inhibitory factor through gp130 in cardiac myocytes. Circulation. 1996;94:2626-2632.
58. Pennica D, King KL, Shaw KJ, Luis E, Rullamas J, Luoh SM, Darbonne WC, Knutzon DS, Yen R, Chien KR. Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy. Proc Natl Acad Sci USA. 1995;92:1142-1146.
59. Wollert KC, Taga T, Saito M, Narazaki M, Kishimoto T, Glembotski CC, Vernallis AB, Heath JK, Pennica D, Wood WI, Chien KR. Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy: assembly of sarcomeric units in series via gp130/leukemia inhibitory factor receptor-dependent pathways. J Biol Chem. 1996;271:9535-9545.
60. Jin H, Yang R, Keller GA, Ryan A, KO A, Finkle D, Swanson TA, Li W, Pennica D, Wood WI, Paoni NF. In vivo effects of cardiotrophin-1. Cytokines. 1996;12:920-926.