Urocortin prevents mitochondrial permeability transition in response to reperfusion injury indirectly by reducing oxidative stress

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 293, Issue 2, 2007, Pages

  Townsend, Paul A ^a,b   Davidson, Sean M ^c   Clarke, Samantha J ^d   Khaliulin, Igor ^d   Carroll, Christopher J ^b   Scarabelli, Tiziano M ^e   Knight, Richard A ^b   Stephanou, Anastasis ^b   Latchman, David S ^b   Halestrap, Andrew P ^d  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

^e WAYNE STATE UNIVERSITY   (United States)

Author keywords

Mitochondria; Oxygen radicals; Peptide hormones

Indexed keywords

LACTATE DEHYDROGENASE; PROTEIN KINASE C ALPHA; PROTEIN KINASE C EPSILON; UROCORTIN;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENZYME RELEASE; HEART HEMODYNAMICS; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PERFUSION; MALE; MITOCHONDRIAL PERMEABILITY; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CARBONYLATION; RAT; REOXYGENATION; REPERFUSION; REPERFUSION INJURY;

ALKALOIDS; ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; BENZOPHENANTHRIDINES; CALCIUM; CARDIOTONIC AGENTS; CELL DEATH; CELL LINE; CORTICOTROPIN-RELEASING HORMONE; HEART; MALE; MITOCHONDRIA, HEART; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCARDIAL CONTRACTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; MYOCYTES, CARDIAC; NECROSIS; OXIDATIVE STRESS; PROTEIN CARBONYLATION; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TIME FACTORS; VENTRICULAR PRESSURE;

EID: 34547884677     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01135.2006     Document Type: Article

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