Cardiotrophin-1 induces heat shock protein accumulation in cultured cardiac cells and protects them from stressful stimuli

Journal of Molecular and Cellular Cardiology

Volumn 30, Issue 4, 1998, Pages 849-855

  Stephanou, A ^a   Brar, B ^a   Heads, R ^b   Knight, R D ^c   Marber, M S ^b   Pennica, D ^d   Latchman, D S ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b ST THOMAS HOSPITAL   (United Kingdom)

^c ROYAL BROMPTON HOSPITAL   (United Kingdom)

^d GENENTECH INC   (United States)

Author keywords

Apoptosis; Cardioprotection; CT 1; Heat shock proteins

Indexed keywords

CARDIOTROPHIN 1; HEAT SHOCK PROTEIN; LACTATE DEHYDROGENASE; TRYPAN BLUE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOACCUMULATION; CELL CULTURE; CELL DEATH; CONTROLLED STUDY; HEART MUSCLE CELL; HEART PROTECTION; HEART VENTRICLE HYPERTROPHY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; STRESS;

ANIMALIA;

EID: 0032053483     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1998.0651     Document Type: Article

References (26)

1. AKIRA S, ISSHIKI H, SUGITA T, TANABE O, KINOSHITA S, NISHIO Y, NAKAJIMA T, HIRANO T, KISHIMOTO T, 1990. A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family. EMBO J 9: 1897-1906.
2. AKIRA S, NISHIO Y, INOUE M, WANG X-J, WEI S, MATSUSAKA T, YOSHIDA K, SUDO T, NARUTO M, KISHIMOTO T, 1994. Molecular cloning of APRF, a novel IFN-stimulated Gene factor 3 p91 related transcription factor involved in the gp130 mediated signaling pathway. Cell 77: 63-71.
3. CHIEN KR, SEN A, REYNOLDS R, CHANG A, KIM Y, GUNN MD, BUJA LM, WILLERSON JT, 1985. Release of arachidonate from membrane phospholipids in cultured neonatal rat myocardial cells during adenosine triphosphate depletion. j Clin Invest 75: 1770-1780.
4. CUMMING DVE, HEADS RJ, BRAND NJ, YELLON DM, LATCHMAN DS, 1996a. The ability of heat stress and metabolic preconditioning to protect primary rat cardiac myocytes. Basic Res Cardiol 9: 79-85.
5. CUMMING DVE, HEADS RJ, WATSON A, LATCHMAN DS, YELLON DM, 1996b. Differential protection of primary rat cardiocytes by transfection of specific heat stress proteins. J Mol Cell Cardiol 28: 2343-2349.
6. ESUMI K, NISHIDA M, SHAW D, SMITH TW, MARSH JD, 1991. NADH measurements in adult rat myocytes during simulated ischaemia. Am J Physiol 29: H1743-H1752.
7. GAVRIELI Y, SHERMAN Y, BEN-SASSON SA, 1992. Identification of programmed cell death in situ via specific labelling of nuclear DNA fragmentation. J Cell Biol 119: 493-501.
8. HEADS RJ, LATCHMAN DS, YELLON DM, 1994. Stable high level expression of a transfected human hsp70 gene protects a heat-derived cell line against thermal stress. J Mol Cell Cardiol 26: 695-699.
9. HEADS RJ, YELLON DM, LATCHMAN DS, 1995. Differential cytoprotection against heat stress or hypoxia following expression of specific stress protein goes in myogenic cells. J Mol Cell Cardiol 27: 1669-1678.
10. KISHIMOTO T, TAGA T, AKIRA S, 1994. Cytokine Signal Transduction. Cell 76: 253-262.
11. KISHIMOTO T, AKIRA S, NARAZAKI M, TAGA T, 1995. Interleukin-6 family of cytokines and gp130. Blood 86: 1243-1254.
12. MARBER MS, MESTRIL R, CHI S-H, SAYEN R, YELLON DM, DILLMANN WH, 1995. Overexpression of the rat inducible 70 kiloDalton heat stress protein in transgenic mouse increases resistance of the heart to ischemic injury. J Clin Invest 95: 1446-1456.
13. MELINO G, ANNICCHIARICO-PETRUZZELLI M, PIREDDA L, CANDI E, GENTILE V, DAVIES PJ, PIACENTINI M, 1994. Tissue transglutaminase and apoptosis: sense and antisense transfection studies with human neuroblastoma cells. Mol Cell Biol 14: 6584-6596.
14. MORRIS SD, GUMMING DVE, LATCHMAN DS, YELLON DS, 1996. Specific induction of the 70 kDa heat stress proteins by the tyrosine kinase inhibitor herbimycin-A protects rat neonatal cardiomyocytes: a new pharmacological route to stress protein expression. J Clin Invest 97: 706-712.
15. NAKAJIMA T, KINOSHITA S, SASAGAWA T, SASAKI K, NARUTO M, KISHIMOTO T, AKIRA S, 1993. Phosphorylation at threonine-235 by a ras-dependent mitogen activated protein kinase cascade is essential for transcription factor NF-IL6. Proc Natl Acad Sci 90: 2207-2211.
16. NELSON SK, WONG GH, MCCORD JM, 1995. Leukemia inhibitory factor and tumor necrosis factor induce manganese superoxide dismutase and protect rabbit hearts from reperfusion injury. J Mol Cell Cardiol 27: 223-229.
17. PENNICA D, KING KL, SHAW KJ, LUIS E, RULLAMAS J, LUOH SM, DARBONNE WC, KNUTZON DS, YEN R, CHIEN KR, BAKER JB, WOOD WI, 1995a. Expression cloning of cardiotrophin 1 a cytokine that induces cardiac myocyte hypertrophy. Proc Natl Acad Sci USA 92: 1142-1146.
18. PENNICA D, SHAW KJ, SWANSON TA, MOORE MW, SHELTON DL, ZIONCHECK KA, ROSENTHAL A, TAGA T, PAONI NF, WOOD WI, 1995b. Cardiotrophin-1: Biological activities and binding to the leukemia inhibitory factor receptor/ gp130 signaling complex. J Biol Chem 270: 10915-10922.
19. PENNICA D, WOOD WI, CHIEN KR, 1996. Cardiotrophin-1: a multifunctional cytokine that signals via LIF receptor gp130 dependent pathways. Cytokine Growth Factor Rev 7: 81-91.
20. SHENG Z, KNOWLTON K, CHEN J, HOSHIJIMA M, BROWN JH, CHIEN KR, 1996a. Cardiotrophin-1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. J Biol Chem 272: 5783-5791.
21. SHENG Z, PENNICA D, WOOD WI, CHIEN KR, 1996b. Cardiotrophin-1 displays early expression in the murine heart tube and promotes cardiac myocyte survival. Development 122: 419-428.
22. SIMPSON P, SAVION S, 1982. Differentiation of rat myocytes in single cell cultures with and without proliferating non myocardial cells. Circ Res 50: 101-116.
23. STEPHANOU A, AMIN V, ISENBERG DA, AKIRA S, KISHIMOTO T, LATCHMAN DS, 1997. Interleukin-6 activates heat shock protein 90β gene expression. Biochem J 321: 103-106.
24. WEGENKA UM, BUSCHMANN J, LUTTICKEN C, HEINRICH PC, HORN F, 1993. Acute-phase response factor, a nuclear factor binding is acute-phase response elements, is rapidly activated by interleukin-6 at the post-translational level. Mol Cell Biol 13: 276-288.
25. WOLLERT KC, TAGA T, SAITO M, NARAZAKI M, KISHIMOTO T, GLEMBOTSKI CC, VERNALLIS AB, HEATH JK, PENNICA D, WOOD WI, CHIEN KR, 1996. Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy. J Biol Chem 271: 9535-9545.
26. YELLON DM, LATCHMAN DS, 1992. Stress proteins and myocardial protection. J Mol Cell Cardiol 24: 113-124.