The cardioprotective actions of leptin are lost in the zucker obese (fa/fa) rat

Journal of Cardiovascular Pharmacology

Volumn 53, Issue 4, 2009, Pages 311-317

  Dixon, Richard A ^a   Davidson, Sean M ^a   Wynne, Abigail M ^a   Yellon, Derek M ^a   Smith, Christopher C T ^a  

^a UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

Author keywords

Ischemia reperfusion injury; Leptin; Leptin receptor; Obesity

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; LEPTIN; LEPTIN RECEPTOR; PROTEIN KINASE B; PROTEIN P42; PROTEIN P44; UO 126; CARDIOTONIC AGENT; CARRIER PROTEIN; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SERINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HEART INFARCTION; HEART INFARCTION SIZE; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART PROTECTION; ISOLATED HEART; MALE; MEMBRANE PERMEABILITY; MITOCHONDRIAL PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION INJURY; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE; WISTAR RAT; ZUCKER DIABETIC FATTY RAT; ZUCKER RAT; ANIMAL; BIOLOGICAL MODEL; CYTOLOGY; DRUG EFFECT; HEART VENTRICLE; METABOLISM; OBESITY; PATHOLOGY; PHOSPHORYLATION;

ANIMALS; CARDIOTONIC AGENTS; HEART VENTRICLES; LEPTIN; MALE; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MODELS, BIOLOGICAL; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; OBESITY; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, ZUCKER; RECEPTORS, LEPTIN; SERINE;

EID: 67650364184     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/FJC.0b013e31819d6152     Document Type: Article

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