메뉴 건너뛰기




Volumn 2, Issue 2, 2000, Pages 62-69

Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation

Author keywords

[No Author keywords available]

Indexed keywords

EPHA2 KINASE; EPHRIN; FIBRONECTIN; FOCAL ADHESION KINASE; INTEGRIN; LAMININ; PAXILLIN; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

EID: 0033785409     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/35000008     Document Type: Article
Times cited : (487)

References (49)
  • 2
    • 0031559401 scopus 로고    scopus 로고
    • Unified nomenclature for Eph family receptors and their ligands, the ephrins
    • (1997) Cell , vol.90 , pp. 403-404
  • 3
    • 15844429889 scopus 로고    scopus 로고
    • Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis
    • (1996) Neuron , vol.17 , pp. 9-19
    • Gale, N.W.1
  • 5
    • 0032577446 scopus 로고    scopus 로고
    • Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4
    • (1998) Cell , vol.93 , pp. 741-753
    • Wang, H.U.1    Chen, Z.F.2    Anderson, D.J.3
  • 8
    • 0029082312 scopus 로고
    • In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases
    • (1995) Cell , vol.82 , pp. 359-370
    • Drescher, U.1
  • 9
    • 0030890656 scopus 로고    scopus 로고
    • Eph family transmembrane ligands can mediate repulsive guidance of trunk neural crest migration and motor axon outgrowth
    • (1997) Neuron , vol.18 , pp. 383-396
    • Wang, H.U.1    Anderson, D.J.2
  • 10
    • 0031214537 scopus 로고    scopus 로고
    • Interactions of Eph-related receptors and ligands confer rostrocaudal pattern to trunk neural crest migration
    • (1997) Curr. Biol. , vol.7 , pp. 571-580
    • Krull, C.E.1
  • 13
    • 0023666065 scopus 로고
    • Integrins: A family of cell surface receptors
    • (1987) Cell , vol.48 , pp. 549-554
    • Hynes, R.O.1
  • 16
    • 0026759309 scopus 로고
    • Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation
    • (1992) Nature , vol.358 , pp. 690-692
    • Guan, J.L.1    Shalloway, D.2
  • 19
    • 0025251177 scopus 로고
    • cDNA cloning and characterization of eck, an epithelial cell receptor protein-tyrosine kinase in the eph/elk family of protein kinases
    • (1990) Mol. Cell Biol. , vol.10 , pp. 6316-6324
    • Lindberg, R.A.1    Hunter, T.2
  • 20
    • 0031001812 scopus 로고    scopus 로고
    • Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells
    • (1997) EMBO J. , vol.16 , pp. 3877-3888
    • Holland, S.J.1
  • 21
    • 0028285015 scopus 로고
    • Integrin cytoplasmic domains mediate inside-out signal transduction
    • (1994) J. Cell Biol. , vol.124 , pp. 1047-1059
    • O'Toole, T.E.1
  • 23
  • 25
    • 0028110068 scopus 로고
    • Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity
    • (1994) Science , vol.266 , pp. 816-819
    • Davis, S.1
  • 27
    • 0029971297 scopus 로고    scopus 로고
    • A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK
    • (1996) Nature , vol.380 , pp. 538-540
    • Richardson, A.1    Parsons, T.2
  • 33
    • 0030589481 scopus 로고    scopus 로고
    • Focal adhesion and stress fiber formation is regulated by tyrosine phosphatase activity
    • (1996) Exp. Cell Res. , vol.229 , pp. 307-317
    • Retta, S.F.1
  • 34
    • 0028792065 scopus 로고
    • p125FAK tyrosine phosphorylation and focal adhesion assembly: Studies with phosphotyrosine phosphatase inhibitors
    • (1995) Exp. Cell Res. , vol.221 , pp. 141-152
    • Defilippi, P.1
  • 35
    • 0030297552 scopus 로고    scopus 로고
    • From form to function: Signaling by protein tyrosine phosphatases
    • (1996) Cell , vol.87 , pp. 365-368
    • Tonks, N.K.1    Neel, B.G.2
  • 37
    • 0032484109 scopus 로고    scopus 로고
    • Low molecular weight protein-tyrosine phosphatase tyrosine phosphorylation by c-Src during platelet-derived growth factor-induced mitogenesis correlates with its subcellular targeting
    • (1998) J. Biol. Chem. , vol.273 , pp. 32522-32527
    • Cirri, P.1
  • 43
    • 13144256698 scopus 로고    scopus 로고
    • PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 9779-9784
    • Hock, B.1
  • 44
    • 0032408173 scopus 로고    scopus 로고
    • PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands
    • (1998) Neuron , vol.21 , pp. 1453-1463
    • Torres, R.1
  • 46
    • 0031057545 scopus 로고    scopus 로고
    • AL-1-induced growth cone collapse of rat cortical neurons is correlated with REK7 expression and rearrangement of the actin cytoskeleton
    • (1997) Eur. J. Neurosci. , vol.9 , pp. 177-188
    • Meima, L.1
  • 47
    • 0033560751 scopus 로고    scopus 로고
    • Surface densities of ephrin-B1 determine EphB1-coupled activation of cell attachment through alphavbeta3 and alpha5beta1 integrins
    • (1999) EMBO J. , vol.18 , pp. 2165-2173
    • Huynh-Do, U.1
  • 48
    • 0032031705 scopus 로고    scopus 로고
    • Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses
    • (1998) Genes Dev. , vol.12 , pp. 667-678
    • Stein, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.