Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes

Journal of Biological Chemistry

Volumn 280, Issue 46, 2005, Pages 38879-38887

  Chen, Chang Shi ^a   Weng, Shu Chuan ^a   Tseng, Ping Hui ^a   Lin, Ho Pi ^a   Chen, Ching Shih ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DRUG PRODUCTS; GENETIC ENGINEERING; POLYPROPYLENES; PROTEINS; TUMORS;

ANTINEOPLASTIC EFFECTS; HISTONE ACETYLATION; HISTONE DEACETYLASES; U87MG GLIOBLASTOMA;

ENZYME INHIBITION;

HDAC42; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; N (2 AMINOPHENYL) 4 (3 PYRIDINYLMETHOXYCARBONYLAMINOMETHYL)BENZAMIDE; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOINOSITIDE DEPENDENT KINASE 1; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOTRANSFERASE; PROTEIN KINASE B; TRICHOSTATIN A; TUBULIN; UNCLASSIFIED DRUG; VORINOSTAT; CALYCULIN A; ENZYME INHIBITOR; HISTONE; HYDROXAMIC ACID; ISOPROTEIN; OKADAIC ACID; OXAZOLE DERIVATIVE; PHOSPHATIDYLINOSITOL; PHOSPHOPROTEIN PHOSPHATASE; PYRAN DERIVATIVE; SERINE; SMALL INTERFERING RNA; SPIRO COMPOUND; TAUTOMYCIN; THREONINE; TYPE 1 SERINE THREONINE PROTEIN PHOSPHATASE;

ACETYLATION; APOPTOSIS; ARTICLE; CANCER CELL; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; DEPHOSPHORYLATION; DOWN REGULATION; DRUG ACTIVITY; ENZYME ACTIVATION; ENZYME ACTIVITY; FLOW CYTOMETRY; FRACTIONATION; GLIOBLASTOMA; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOCHEMISTRY; PRIORITY JOURNAL; PROSTATE CANCER; CELL CYCLE; CELL FRACTIONATION; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; METABOLISM; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION; TIME; TUMOR CELL LINE;

APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME INHIBITORS; HISTONE DEACETYLASES; HISTONES; HUMANS; HYDROXAMIC ACIDS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; OKADAIC ACID; OXAZOLES; PHOSPHATIDYLINOSITOLS; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-AKT; PYRANS; RNA, SMALL INTERFERING; SERINE; SIGNAL TRANSDUCTION; SPIRO COMPOUNDS; SUBCELLULAR FRACTIONS; THREONINE; TIME FACTORS;

EID: 33644663872     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M505733200     Document Type: Article

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