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Volumn 5, Issue 6, 2010, Pages 491-498

DNA methylation in endometrial cancer

Author keywords

DNA methylation; Endometrial cancer; Epidemiology

Indexed keywords

CARCINOGENESIS; DIET; DNA METHYLATION; ENDOMETRIUM CANCER; GENE EXPRESSION; HUMAN; LIFESTYLE; REVIEW;

EID: 77957365492     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.5.6.12431     Document Type: Review
Times cited : (83)

References (147)
  • 1
    • 67650385302 scopus 로고    scopus 로고
    • American Cancer Society
    • American Cancer Society. (2009) Cancer Facts and Figures 2009. www.cancer.org.
    • (2009) Cancer Facts and Figures 2009
  • 3
    • 0023279926 scopus 로고
    • The inheritance of epigenetic defects
    • Holliday R. The inheritance of epigenetic defects. Science 1987; 238:163-70.
    • (1987) Science , vol.238 , pp. 163-170
    • Holliday, R.1
  • 4
    • 0033153303 scopus 로고    scopus 로고
    • The human DNA methyltransferases (DNMTs) 1, 3a and 3b: Coordinate mRNA expression in normal tissues and overexpression in tumors
    • Robertson KD, Uzvolgyi E, Liang G, Talmadge C, Sumegi J, Gonzales FA, et al. The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res 1999; 27:2291-8.
    • (1999) Nucleic Acids Res , vol.27 , pp. 2291-2298
    • Robertson, K.D.1    Uzvolgyi, E.2    Liang, G.3    Talmadge, C.4    Sumegi, J.5    Gonzales, F.A.6
  • 5
    • 31544456085 scopus 로고    scopus 로고
    • The role of mammalian DNA methyltransferases in the regulation of gene expression
    • Turek-Plewa J, Jagodzinski PP. The role of mammalian DNA methyltransferases in the regulation of gene expression. Cell Mol Biol Lett 2005; 10:631-47.
    • (2005) Cell Mol Biol Lett , vol.10 , pp. 631-647
    • Turek-Plewa, J.1    Jagodzinski, P.P.2
  • 6
    • 29644443860 scopus 로고    scopus 로고
    • DNA methyltransferases: Facts, clues, mysteries
    • Brenner C, Fuks F. DNA methyltransferases: facts, clues, mysteries. Curr Top Microbiol Immunol 2006; 301:45-66.
    • (2006) Curr Top Microbiol Immunol , vol.301 , pp. 45-66
    • Brenner, C.1    Fuks, F.2
  • 8
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman JG, Baylin SB. Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 2003; 349:2042-54.
    • (2003) N Engl J Med , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 9
    • 0028940587 scopus 로고
    • Gene number, noise reduction and biological complexity
    • Bird AP. Gene number, noise reduction and biological complexity. Trends Genet 1995; 11:94-100.
    • (1995) Trends Genet , vol.11 , pp. 94-100
    • Bird, A.P.1
  • 10
    • 22844457491 scopus 로고    scopus 로고
    • DNA methylation and human disease
    • Robertson KD. DNA methylation and human disease. Nat Rev Genet 2005; 6:597-610.
    • (2005) Nat Rev Genet , vol.6 , pp. 597-610
    • Robertson, K.D.1
  • 11
    • 0035839126 scopus 로고    scopus 로고
    • Epigenetic reprogramming in mammalian development
    • Reik W, Dean W, Walter J. Epigenetic reprogramming in mammalian development. Science 2001; 293: 1089-93.
    • (2001) Science , vol.293 , pp. 1089-1093
    • Reik, W.1    Dean, W.2    Walter, J.3
  • 13
    • 0031467130 scopus 로고    scopus 로고
    • X-chromosome inactivation in mammals
    • Heard E, Clerc P, Avner P. X-chromosome inactivation in mammals. Annu Rev Genet 1997; 31:571-610.
    • (1997) Annu Rev Genet , vol.31 , pp. 571-610
    • Heard, E.1    Clerc, P.2    Avner, P.3
  • 15
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • Esteller M. Epigenetics in cancer. N Engl J Med 2008; 358:1148-59.
    • (2008) N Engl J Med , vol.358 , pp. 1148-1159
    • Esteller, M.1
  • 16
    • 0034929515 scopus 로고    scopus 로고
    • DNA methylation: An alternative pathway to cancer
    • Wajed SA, Laird PW, DeMeester TR. DNA methylation: an alternative pathway to cancer. Ann Surg 2001; 234:10-20.
    • (2001) Ann Surg , vol.234 , pp. 10-20
    • Wajed, S.A.1    Laird, P.W.2    Demeester, T.R.3
  • 17
    • 49449115492 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expressio in the inflammatory response and relevance to common disease
    • Wilson AG. Epigenetic regulation of gene expressio in the inflammatory response and relevance to common disease. J Periodontol 2008; 79:1514-9.
    • (2008) J Periodontol , vol.79 , pp. 1514-1519
    • Wilson, A.G.1
  • 19
    • 0020699979 scopus 로고
    • Hypomethylation distinguishes genes of some human cancers from their normal counterparts
    • Feinberg AP, Vogelstein B. Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 1983; 301:89-92.
    • (1983) Nature , vol.301 , pp. 89-92
    • Feinberg, A.P.1    Vogelstein, B.2
  • 20
  • 22
    • 0037068360 scopus 로고    scopus 로고
    • DNA methylation and breast carcinogenesis
    • Widschwendter M, Jones PA. DNA methylation and breast carcinogenesis. Oncogene 2002; 21:5462-82.
    • (2002) Oncogene , vol.21 , pp. 5462-5482
    • Widschwendter, M.1    Jones, P.A.2
  • 24
    • 12144280302 scopus 로고    scopus 로고
    • Epigenetics, mismatch repair genes and colorectal cancer
    • Wheeler JMD. Epigenetics, mismatch repair genes and colorectal cancer. Ann R Coll Surg Engl 2005; 87: 15-20.
    • (2005) Ann R Coll Surg Engl , vol.87 , pp. 15-20
    • Wheeler, J.M.D.1
  • 25
  • 27
    • 0033556428 scopus 로고    scopus 로고
    • Causes and consequences of microsatellite instability in endometrial carcinoma
    • Gurin CC, Federici MG, Kang L, Boyd J. Causes and consequences of microsatellite instability in endometrial carcinoma. Cancer Res 1999; 59:462-6.
    • (1999) Cancer Res , vol.59 , pp. 462-466
    • Gurin, C.C.1    Federici, M.G.2    Kang, L.3    Boyd, J.4
  • 29
    • 0029122057 scopus 로고
    • Microsatellite instability in endometrial carcinomas: Frequent replication errors in tumors of early onset and/or of poorly differentiated type
    • Kobayashi K, Sagae S, Kudo R, Saito H, Koi S, Nakamura Y. Microsatellite instability in endometrial carcinomas: frequent replication errors in tumors of early onset and/or of poorly differentiated type. Genes Chromosomes Cancer 1995; 14:128-32.
    • (1995) Genes Chromosomes Cancer , vol.14 , pp. 128-132
    • Kobayashi, K.1    Sagae, S.2    Kudo, R.3    Saito, H.4    Koi, S.5    Nakamura, Y.6
  • 30
    • 0036024596 scopus 로고    scopus 로고
    • Chromosomal abnormalities and microsatellite instability in sporadic endometrial cancer
    • Muresu R, Sini MC, Cossu A, Tore S, Baldinu P, Manca A, et al. Chromosomal abnormalities and microsatellite instability in sporadic endometrial cancer. Eur J Cancer 2002; 38:1802-9.
    • (2002) Eur J Cancer , vol.38 , pp. 1802-1809
    • Muresu, R.1    Sini, M.C.2    Cossu, A.3    Tore, S.4    Baldinu, P.5    Manca, A.6
  • 31
    • 0032487831 scopus 로고    scopus 로고
    • MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas
    • Esteller M, Levine R, Baylin SB, Ellenson LH, Herman JG. MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas. Oncogene 1998; 17:2413-7.
    • (1998) Oncogene , vol.17 , pp. 2413-2417
    • Esteller, M.1    Levine, R.2    Baylin, S.B.3    Ellenson, L.H.4    Herman, J.G.5
  • 32
    • 0028883556 scopus 로고
    • Mutations in DNA mismatch repair genes are not responsible for microsatellite instability in most sporadic endometrial carcinomas
    • Katabuchi H, van Rees B, Lambers AR, Ronnett BM, Blazes MS, Leach FS, et al. Mutations in DNA mismatch repair genes are not responsible for microsatellite instability in most sporadic endometrial carcinomas. Cancer Res 1995; 155:5556-60.
    • (1995) Cancer Res , vol.155 , pp. 5556-5560
    • Katabuchi, H.1    van Rees, B.2    Lambers, A.R.3    Ronnett, B.M.4    Blazes, M.S.5    Leach, F.S.6
  • 33
    • 0030005834 scopus 로고    scopus 로고
    • Mutational analysis of mismatch repair genes, hMLH1 and hMSH2, in sporadic endometrial carcinomas with microsatellite instability
    • Kobayashi K, Matsushima M, Koi S, Saito H, Sagae S, Kudo R, et al. Mutational analysis of mismatch repair genes, hMLH1 and hMSH2, in sporadic endometrial carcinomas with microsatellite instability. Jpn J Cancer Res 1996; 87:141-5.
    • (1996) Jpn J Cancer Res , vol.87 , pp. 141-145
    • Kobayashi, K.1    Matsushima, M.2    Koi, S.3    Saito, H.4    Sagae, S.5    Kudo, R.6
  • 34
    • 0029846318 scopus 로고    scopus 로고
    • Absence of mutations in DNA mismatch repair genes in sporadic endometrial tumors with microsatellite instability
    • Lim PC, Tester D, Cliby W, Ziesmer SC, Roche PC, Hartmann L, et al. Absence of mutations in DNA mismatch repair genes in sporadic endometrial tumors with microsatellite instability. Clin Cancer Res 1996; 2:1907-11.
    • (1996) Clin Cancer Res , vol.2 , pp. 1907-1911
    • Lim, P.C.1    Tester, D.2    Cliby, W.3    Ziesmer, S.C.4    Roche, P.C.5    Hartmann, L.6
  • 35
    • 0034020502 scopus 로고    scopus 로고
    • Altered expression of hMLH1 and hMSH2 protein in endometrial carcinomas with microsatellite instability
    • Staebler A, Lax SF, Ellenson LH. Altered expression of hMLH1 and hMSH2 protein in endometrial carcinomas with microsatellite instability. Hum Pathol 2000; 31:354-8.
    • (2000) Hum Pathol , vol.31 , pp. 354-358
    • Staebler, A.1    Lax, S.F.2    Ellenson, L.H.3
  • 36
    • 0036152444 scopus 로고    scopus 로고
    • Loss of hMSH2 and hMSH6 expression is frequent in sporadic endometrial carcinomas with microsatellite instability: A population-based study
    • Stefansson I, Akslen LA, MacDonald N, Ryan A, Das S, Jacobs IJ, et al. Loss of hMSH2 and hMSH6 expression is frequent in sporadic endometrial carcinomas with microsatellite instability: a population-based study. Clin Cancer Res 2002; 8:138-43.
    • (2002) Clin Cancer Res , vol.8 , pp. 138-143
    • Stefansson, I.1    Akslen, L.A.2    MacDonald, N.3    Ryan, A.4    Das, S.5    Jacobs, I.J.6
  • 37
    • 0037096949 scopus 로고    scopus 로고
    • Microsatellite instability and mutation analysis of candidate genes in unselected sardinian patients with endometrial carcinoma
    • Baldinu P, Cossu A, Manca A, Satta MP, Pisano M, Casula M, et al. Microsatellite instability and mutation analysis of candidate genes in unselected sardinian patients with endometrial carcinoma. Cancer 2002; 94:3157-68.
    • (2002) Cancer , vol.94 , pp. 3157-3168
    • Baldinu, P.1    Cossu, A.2    Manca, A.3    Satta, M.P.4    Pisano, M.5    Casula, M.6
  • 38
    • 0034264425 scopus 로고    scopus 로고
    • Not hMSH2 but hMLH1 is frequently silenced by hypermethylation in endometrial cancer but rarely silenced in pancreatic cancer with microsatellite instability
    • Kondo E, Furukawa T, Yoshinaga K, Kijima H, Semba S, Yatsuoka T, et al. Not hMSH2 but hMLH1 is frequently silenced by hypermethylation in endometrial cancer but rarely silenced in pancreatic cancer with microsatellite instability. Int J Cancer 2000; 17: 535-41.
    • (2000) Int J Cancer , vol.17 , pp. 535-541
    • Kondo, E.1    Furukawa, T.2    Yoshinaga, K.3    Kijima, H.4    Semba, S.5    Yatsuoka, T.6
  • 39
    • 0031017268 scopus 로고    scopus 로고
    • Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines
    • Kane MF, Loda M, Gaida GM, Lipman J, Mishra R, Goldman H, et al. Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res 1997; 57:808-11.
    • (1997) Cancer Res , vol.57 , pp. 808-811
    • Kane, M.F.1    Loda, M.2    Gaida, G.M.3    Lipman, J.4    Mishra, R.5    Goldman, H.6
  • 41
  • 42
    • 0033105363 scopus 로고    scopus 로고
    • Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability
    • Fleisher AS, Esteller M, Wang S, Tamura G, Suzuki H, Yin J, et al. Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability. Cancer Res 1999; 59:1090-5.
    • (1999) Cancer Res , vol.59 , pp. 1090-1095
    • Fleisher, A.S.1    Esteller, M.2    Wang, S.3    Tamura, G.4    Suzuki, H.5    Yin, J.6
  • 43
    • 0032997736 scopus 로고    scopus 로고
    • MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers
    • Simpkins SB, Bocker T, Swisher EM, Mutch DG, Gersell DJ, Kovatich AJ, et al. MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers. Hum Mol Genet 1999; 8:661-6.
    • (1999) Hum Mol Genet , vol.8 , pp. 661-666
    • Simpkins, S.B.1    Bocker, T.2    Swisher, E.M.3    Mutch, D.G.4    Gersell, D.J.5    Kovatich, A.J.6
  • 45
    • 34249949422 scopus 로고    scopus 로고
    • Microsatellite instability and epigenetic inactivation of MLH1 and outcome of patients with endometrial carcinomas of the endometrioid type
    • Zighelboim I, Goodfellow PJ, Gao F, Gibb RK, Powell MA, Rader JS, et al. Microsatellite instability and epigenetic inactivation of MLH1 and outcome of patients with endometrial carcinomas of the endometrioid type. J Clin Oncol 2007; 25:2042-8.
    • (2007) J Clin Oncol , vol.25 , pp. 2042-2048
    • Zighelboim, I.1    Goodfellow, P.J.2    Gao, F.3    Gibb, R.K.4    Powell, M.A.5    Rader, J.S.6
  • 46
    • 13144266670 scopus 로고    scopus 로고
    • Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
    • Herman JG, Uma A, Polyak K, Graff JR, Ahuja N, Issa JP, et al. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci USA 1998; 95:6870-5.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6870-6875
    • Herman, J.G.1    Uma, A.2    Polyak, K.3    Graff, J.R.4    Ahuja, N.5    Issa, J.P.6
  • 47
    • 0032706744 scopus 로고    scopus 로고
    • hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis
    • Esteller M, Catasus L, Matias-Guiu X, Mutter GL, Prat J, Baylin SB, et al. hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis. Am J Pathol 1999; 155:1767-72.
    • (1999) Am J Pathol , vol.155 , pp. 1767-1772
    • Esteller, M.1    Catasus, L.2    Matias-Guiu, X.3    Mutter, G.L.4    Prat, J.5    Baylin, S.B.6
  • 48
    • 0036311084 scopus 로고    scopus 로고
    • Microsatellite instability, MLH1 promoter methylation, and loss of mismatch repair in endometrial cancer and concomitant atypical hyperplasia
    • Horowitz N, Pinto K, Mutch DG, Herzog TJ, Rader JS, Gibb R, et al. Microsatellite instability, MLH1 promoter methylation, and loss of mismatch repair in endometrial cancer and concomitant atypical hyperplasia. Gynecol Oncol 2002; 86:62-8.
    • (2002) Gynecol Oncol , vol.86 , pp. 62-68
    • Horowitz, N.1    Pinto, K.2    Mutch, D.G.3    Herzog, T.J.4    Rader, J.S.5    Gibb, R.6
  • 49
    • 21744443077 scopus 로고    scopus 로고
    • Association of mismatch repair deficiency with PTEN frameshift mutations in endometrial cancers and the precursors in a Japanese population
    • Kanaya T, Kyo S, Sakaguchi J, Maida Y, Nakamura M, Takakura M, et al. Association of mismatch repair deficiency with PTEN frameshift mutations in endometrial cancers and the precursors in a Japanese population. Am J Clin Pathol 2005; 124:89-96.
    • (2005) Am J Clin Pathol , vol.124 , pp. 89-96
    • Kanaya, T.1    Kyo, S.2    Sakaguchi, J.3    Maida, Y.4    Nakamura, M.5    Takakura, M.6
  • 50
    • 34548711004 scopus 로고    scopus 로고
    • Relationship of the aberrant DNA hypermethylation of cancer-related genes with carcinogenesis of endometrial cancer
    • Banno K, Yanokura M, Susumu N, Kawaguchi M, Hirao N, Hirasawa A, et al. Relationship of the aberrant DNA hypermethylation of cancer-related genes with carcinogenesis of endometrial cancer. Oncol Rep 2006; 16:1189-96.
    • (2006) Oncol Rep , vol.16 , pp. 1189-1196
    • Banno, K.1    Yanokura, M.2    Susumu, N.3    Kawaguchi, M.4    Hirao, N.5    Hirasawa, A.6
  • 51
    • 67649760326 scopus 로고    scopus 로고
    • Aberrant DNA hypermethylation of hMLH-1 and CDKN2A/p16 genes in benign, premalignant and malignant endometrial lesions
    • Guida M, Sanguedolce F, Bufo P, Di Spiezio Sardo A, Bifulco G, Nappi C, et al. Aberrant DNA hypermethylation of hMLH-1 and CDKN2A/p16 genes in benign, premalignant and malignant endometrial lesions. Eur J Gynaecol Oncol 2009; 30:267-70.
    • (2009) Eur J Gynaecol Oncol , vol.30 , pp. 267-270
    • Guida, M.1    Sanguedolce, F.2    Bufo, P.3    di Spiezio Sardo, A.4    Bifulco, G.5    Nappi, C.6
  • 52
    • 0024543557 scopus 로고
    • Abnormal methylation of estrogen receptor gene and reduced estrogen receptor RNA levels in human endometrial carcinomas
    • Piva R, Kumar VL, Hanau S, Rimondi AP, Pansini S, Mollica G, et al. Abnormal methylation of estrogen receptor gene and reduced estrogen receptor RNA levels in human endometrial carcinomas. J Steroid Biochem 1989; 32:1-4.
    • (1989) J Steroid Biochem , vol.32 , pp. 1-4
    • Piva, R.1    Kumar, V.L.2    Hanau, S.3    Rimondi, A.P.4    Pansini, S.5    Mollica, G.6
  • 53
    • 0035870261 scopus 로고    scopus 로고
    • Cytosine-phosphoguanine methylation of estrogen receptors in endometrial cancer
    • Sasaki M, Kotcherguina L, Dharia A, Fujimoto S, Dahiya R. Cytosine-phosphoguanine methylation of estrogen receptors in endometrial cancer. Cancer Res 2001; 61:3262-6.
    • (2001) Cancer Res , vol.61 , pp. 3262-3266
    • Sasaki, M.1    Kotcherguina, L.2    Dharia, A.3    Fujimoto, S.4    Dahiya, R.5
  • 54
    • 0033978018 scopus 로고    scopus 로고
    • Assessment of hypermethylated DNA in two promoter regions of the estrogen receptor alpha gene in human endometrial diseases
    • Hori M, Iwasaki M, Shimazaki J, Inagawa S, Itabashi M. Assessment of hypermethylated DNA in two promoter regions of the estrogen receptor alpha gene in human endometrial diseases. Gynecol Oncol 2000; 76:89-96.
    • (2000) Gynecol Oncol , vol.76 , pp. 89-96
    • Hori, M.1    Iwasaki, M.2    Shimazaki, J.3    Inagawa, S.4    Itabashi, M.5
  • 55
    • 0033755178 scopus 로고    scopus 로고
    • Loss of estrogen receptor (ER) expression in endometrial tumors is not associated with de novo methylation of the 5' end of the ER gene
    • Navari JR, Roland PY, Keh P, Salvesen HB, Akslen LA, Iversen OE, et al. Loss of estrogen receptor (ER) expression in endometrial tumors is not associated with de novo methylation of the 5' end of the ER gene. Clin Cancer Res 2000; 6:4026-32.
    • (2000) Clin Cancer Res , vol.6 , pp. 4026-4032
    • Navari, J.R.1    Roland, P.Y.2    Keh, P.3    Salvesen, H.B.4    Akslen, L.A.5    Iversen, O.E.6
  • 56
    • 0036244294 scopus 로고    scopus 로고
    • Downregulation of estrogen receptor by the methylation of the estrogen receptor gene in endometrial carcinoma
    • Shiozawa T, Itoh K, Horiuchi A, Konishi I, Fujii S, Nikaido T. Downregulation of estrogen receptor by the methylation of the estrogen receptor gene in endometrial carcinoma. Anticancer Res 2002; 22:139-43.
    • (2002) Anticancer Res , vol.22 , pp. 139-143
    • Shiozawa, T.1    Itoh, K.2    Horiuchi, A.3    Konishi, I.4    Fujii, S.5    Nikaido, T.6
  • 57
    • 0036280276 scopus 로고    scopus 로고
    • Relationship between p53 pathway and estrogen receptor status in endometrioid-type endometrial cancer
    • Maeda K, Tsuda H, Hashiguchi Y, Yamamoto K, Inoue T, Ishiko O, et al. Relationship between p53 pathway and estrogen receptor status in endometrioid-type endometrial cancer. Hum Pathol 2002; 33:386-91.
    • (2002) Hum Pathol , vol.33 , pp. 386-391
    • Maeda, K.1    Tsuda, H.2    Hashiguchi, Y.3    Yamamoto, K.4    Inoue, T.5    Ishiko, O.6
  • 58
    • 0037613315 scopus 로고    scopus 로고
    • Hypermethylation can selectively silence multiple promoters of steroid receptors in cancers
    • Sasaki M, Kaneuchi M, Fujimoto S, Tanaka Y, Dahiya R. Hypermethylation can selectively silence multiple promoters of steroid receptors in cancers. Mol Cell Endocrinol 2003; 202:201-7.
    • (2003) Mol Cell Endocrinol , vol.202 , pp. 201-207
    • Sasaki, M.1    Kaneuchi, M.2    Fujimoto, S.3    Tanaka, Y.4    Dahiya, R.5
  • 59
    • 0032080677 scopus 로고    scopus 로고
    • Selective downregulation of progesterone receptor isoform B in poorly differentiated human endometrial cancer cells: Implications for unopposed estrogen action
    • Kumar NS, Richer J, Owen G, Litman E, Horwitz KB, Leslie KK. Selective downregulation of progesterone receptor isoform B in poorly differentiated human endometrial cancer cells: implications for unopposed estrogen action. Cancer Res 1998; 58:1860-5.
    • (1998) Cancer Res , vol.58 , pp. 1860-1865
    • Kumar, N.S.1    Richer, J.2    Owen, G.3    Litman, E.4    Horwitz, K.B.5    Leslie, K.K.6
  • 60
    • 0035139039 scopus 로고    scopus 로고
    • Progesterone receptor B gene inactivation and CpG hypermethylation in human uterine endometrial cancer
    • Sasaki M, Dharia A, Oh BR, Tanaka Y, Fujimoto S, Dahiya R. Progesterone receptor B gene inactivation and CpG hypermethylation in human uterine endometrial cancer. Cancer Res 2001; 61:97-102.
    • (2001) Cancer Res , vol.61 , pp. 97-102
    • Sasaki, M.1    Dharia, A.2    Oh, B.R.3    Tanaka, Y.4    Fujimoto, S.5    Dahiya, R.6
  • 61
    • 0036468261 scopus 로고    scopus 로고
    • Progesterone inhibits human endometrial cancer cell growth and invasiveness: Downregulation of cellular adhesion molecules through progesterone B receptors
    • Dai D, Wolf DM, Litman ES, White MJ, Leslie KK. Progesterone inhibits human endometrial cancer cell growth and invasiveness: downregulation of cellular adhesion molecules through progesterone B receptors. Cancer Res 2002; 62:881-6.
    • (2002) Cancer Res , vol.62 , pp. 881-886
    • Dai, D.1    Wolf, D.M.2    Litman, E.S.3    White, M.J.4    Leslie, K.K.5
  • 62
    • 25144454885 scopus 로고    scopus 로고
    • Epigenetic-mediated upregulation of progesterone receptor B gene in endometrial cancer cell lines
    • Xiong Y, Dowdy SC, Gonzalez Bosquet J, Zhao Y, Eberhardt NL, Podratz KC, et al. Epigenetic-mediated upregulation of progesterone receptor B gene in endometrial cancer cell lines. Gynecol Oncol 2005; 99: 135-41.
    • (2005) Gynecol Oncol , vol.99 , pp. 135-141
    • Xiong, Y.1    Dowdy, S.C.2    Gonzalez Bosquet, J.3    Zhao, Y.4    Eberhardt, N.L.5    Podratz, K.C.6
  • 63
    • 34249808191 scopus 로고    scopus 로고
    • Downregulation of the progesterone receptor by the methylation of progesterone receptor gene in endometrial cancer cells
    • Ren Y, Liu X, Ma D, Feng Y, Zhong N. Downregulation of the progesterone receptor by the methylation of progesterone receptor gene in endometrial cancer cells. Cancer Genet Cytogenet 2007; 175:107-16.
    • (2007) Cancer Genet Cytogenet , vol.175 , pp. 107-116
    • Ren, Y.1    Liu, X.2    Ma, D.3    Feng, Y.4    Zhong, N.5
  • 67
    • 0030761409 scopus 로고    scopus 로고
    • Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies
    • Tashiro H, Blazes MS, Wu R, Cho KR, Bose S, Wang SI, et al. Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies. Cancer Res 1997; 27:3935-40.
    • (1997) Cancer Res , vol.27 , pp. 3935-3940
    • Tashiro, H.1    Blazes, M.S.2    Wu, R.3    Cho, K.R.4    Bose, S.5    Wang, S.I.6
  • 69
    • 2342504508 scopus 로고    scopus 로고
    • Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers
    • Goel A, Arnold CN, Niedzwiecki D, Carethers JM, Dowell JM, Wasserman L, et al. Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers. Cancer Res 2004; 64:3014-21.
    • (2004) Cancer Res , vol.64 , pp. 3014-3021
    • Goel, A.1    Arnold, C.N.2    Niedzwiecki, D.3    Carethers, J.M.4    Dowell, J.M.5    Wasserman, L.6
  • 70
    • 4544379915 scopus 로고    scopus 로고
    • Molecular differences between RER+ and RER- sporadic endometrial carcinomas in a large population-based series
    • Macdonald ND, Salvesen HB, Ryan A, Malatos S, Stefansson I, Iversen OE, et al. Molecular differences between RER+ and RER- sporadic endometrial carcinomas in a large population-based series. Int J Gynecol Cancer 2004; 14:957-65.
    • (2004) Int J Gynecol Cancer , vol.14 , pp. 957-965
    • MacDonald, N.D.1    Salvesen, H.B.2    Ryan, A.3    Malatos, S.4    Stefansson, I.5    Iversen, O.E.6
  • 71
    • 16644393813 scopus 로고    scopus 로고
    • Significance of PTEN alterations in endometrial carcinoma: A population-based study of mutations, promoter methylation and PTEN protein expression
    • Salvesen HB, Stefansson I, Kretzschmar EI, Gruber P, MacDonald ND, Ryan A, et al. Significance of PTEN alterations in endometrial carcinoma: a population-based study of mutations, promoter methylation and PTEN protein expression. Int J Oncol 2004; 25.
    • (2004) Int J Oncol , vol.25
    • Salvesen, H.B.1    Stefansson, I.2    Kretzschmar, E.I.3    Gruber, P.4    MacDonald, N.D.5    Ryan, A.6
  • 72
    • 0035196043 scopus 로고    scopus 로고
    • PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma
    • Salvesen HB, MacDonald N, Ryan A, Jacobs IJ, Lynch ED, Akslen LA, et al. PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma. Int J Cancer 2001; 91:22-6.
    • (2001) Int J Cancer , vol.91 , pp. 22-26
    • Salvesen, H.B.1    MacDonald, N.2    Ryan, A.3    Jacobs, I.J.4    Lynch, E.D.5    Akslen, L.A.6
  • 73
    • 0036121266 scopus 로고    scopus 로고
    • Considerations when analyzing the methylation status of PTEN tumor suppressor gene
    • Zysman MA, Chapman WB, Bapat B. Considerations when analyzing the methylation status of PTEN tumor suppressor gene. Am J Pathol 2002; 160:795-800.
    • (2002) Am J Pathol , vol.160 , pp. 795-800
    • Zysman, M.A.1    Chapman, W.B.2    Bapat, B.3
  • 74
    • 0344301900 scopus 로고    scopus 로고
    • Role of the p16 tumor suppressor gene in cancer
    • Liggett WH Jr, Sidransky D. Role of the p16 tumor suppressor gene in cancer. J Clin Oncol 1998; 16:1197-206.
    • (1998) J Clin Oncol , vol.16 , pp. 1197-1206
    • Liggett Jr, W.H.1    Sidransky, D.2
  • 77
    • 33745199586 scopus 로고    scopus 로고
    • The high frequency of de novo promoter methylation in synchronous primary endometrial and ovarian carcinomas
    • Furlan D, Carnevali I, Marcomini B, Cerutti R, Dainese E, Capella C, et al. The high frequency of de novo promoter methylation in synchronous primary endometrial and ovarian carcinomas. Clin Cancer Res 2006; 12:3329-36.
    • (2006) Clin Cancer Res , vol.12 , pp. 3329-3336
    • Furlan, D.1    Carnevali, I.2    Marcomini, B.3    Cerutti, R.4    Dainese, E.5    Capella, C.6
  • 78
    • 33748639077 scopus 로고    scopus 로고
    • Differential DNA methylation profiles in gynecological cancers and correlation with clinico-pathological data
    • Yang HJ, Liu VW, Wang Y, Tsang PC, Ngan HY. Differential DNA methylation profiles in gynecological cancers and correlation with clinico-pathological data. BMC Cancer 2006; 23:212.
    • (2006) BMC Cancer , vol.23 , pp. 212
    • Yang, H.J.1    Liu, V.W.2    Wang, Y.3    Tsang, P.C.4    Ngan, H.Y.5
  • 80
    • 0033979559 scopus 로고    scopus 로고
    • Loss of nuclear p16 protein expression is not associated with promoter methylation but defines a subgroup of aggressive endometrial carcinomas with poor prognosis
    • Salesen HB, Das S, Akslen LA. Loss of nuclear p16 protein expression is not associated with promoter methylation but defines a subgroup of aggressive endometrial carcinomas with poor prognosis. Clin Cancer Res 2000; 153-9.
    • (2000) Clin Cancer Res , pp. 153-159
    • Salesen, H.B.1    Das, S.2    Akslen, L.A.3
  • 82
    • 18144411303 scopus 로고    scopus 로고
    • Role of the Ras-association domain family 1 tumor suppressor gene in human cancers
    • Agathanggelou A, Cooper WN, Latif F. Role of the Ras-association domain family 1 tumor suppressor gene in human cancers. Cancer Res 2005; 65:3497-508.
    • (2005) Cancer Res , vol.65 , pp. 3497-3508
    • Agathanggelou, A.1    Cooper, W.N.2    Latif, F.3
  • 84
    • 54949131345 scopus 로고    scopus 로고
    • High frequency of RASSF1A and RARb2 gene promoter methylation in morphologically normal endometrium adjacent to endometrioid adenocarcinoma
    • Arafa M, Kridelka F, Mathias V, Vanbellinghen JF, Renard I, Foidart JM, et al. High frequency of RASSF1A and RARb2 gene promoter methylation in morphologically normal endometrium adjacent to endometrioid adenocarcinoma. Histopathology 2008; 53:525-32.
    • (2008) Histopathology , vol.53 , pp. 525-532
    • Arafa, M.1    Kridelka, F.2    Mathias, V.3    Vanbellinghen, J.F.4    Renard, I.5    Foidart, J.M.6
  • 85
    • 44349169410 scopus 로고    scopus 로고
    • Promoter hypermethylation and reduced expression of RASSF1A are frequent molecular alterations of endometrial carcinoma
    • Pallarés J, Velasco A, Eritja N, Santacana M, Dolcet X, Cuatrecasas M, et al. Promoter hypermethylation and reduced expression of RASSF1A are frequent molecular alterations of endometrial carcinoma. Mod Pathol 2008; 21:691-9.
    • (2008) Mod Pathol , vol.21 , pp. 691-699
    • Pallarés, J.1    Velasco, A.2    Eritja, N.3    Santacana, M.4    Dolcet, X.5    Cuatrecasas, M.6
  • 86
    • 44949106316 scopus 로고    scopus 로고
    • Hypermethylation of RAS effector related genes and DNA methyltransferase 1 expression in endometrial carcinogenesis
    • Liao X, Siu MK, Chan KY, Wong ES, Ngan HY, Chan QK, et al. Hypermethylation of RAS effector related genes and DNA methyltransferase 1 expression in endometrial carcinogenesis. Int J Cancer 2008; 123:296-302.
    • (2008) Int J Cancer , vol.123 , pp. 296-302
    • Liao, X.1    Siu, M.K.2    Chan, K.Y.3    Wong, E.S.4    Ngan, H.Y.5    Chan, Q.K.6
  • 88
    • 33750978681 scopus 로고    scopus 로고
    • Association of promoter hypermethylation of the RASSF1A gene with prognostic parameters in endometrial cancer
    • Jo H, Kim JW, Kang GH, Park NH, Song YS, Kang SB, et al. Association of promoter hypermethylation of the RASSF1A gene with prognostic parameters in endometrial cancer. Oncol Res 2006; 16:205-9.
    • (2006) Oncol Res , vol.16 , pp. 205-209
    • Jo, H.1    Kim, J.W.2    Kang, G.H.3    Park, N.H.4    Song, Y.S.5    Kang, S.B.6
  • 89
    • 33747463915 scopus 로고    scopus 로고
    • RASSF1A hypermethylation and its inverse correlation with BRAF and/or KRAS mutations in MSI-associated endometrial carcinoma
    • Kang S, Lee JM, Jeon ES, Lee S, Kim H, Kim HS, et al. RASSF1A hypermethylation and its inverse correlation with BRAF and/or KRAS mutations in MSI-associated endometrial carcinoma. Int J Cancer 2006; 119: 1316-21.
    • (2006) Int J Cancer , vol.119 , pp. 1316-1321
    • Kang, S.1    Lee, J.M.2    Jeon, E.S.3    Lee, S.4    Kim, H.5    Kim, H.S.6
  • 91
    • 0037431542 scopus 로고    scopus 로고
    • Hypermethylation of the tumor suppressor gene RASSFIA and frequent concomitant loss of heterozygosity at 3p21 in cervical cancers
    • Yu MY, Tong JH, Chan PK, Lee TL, Chan MW, Chan AW, et al. Hypermethylation of the tumor suppressor gene RASSFIA and frequent concomitant loss of heterozygosity at 3p21 in cervical cancers. Int J Cancer 2003; 105:204-9.
    • (2003) Int J Cancer , vol.105 , pp. 204-209
    • Yu, M.Y.1    Tong, J.H.2    Chan, P.K.3    Lee, T.L.4    Chan, M.W.5    Chan, A.W.6
  • 92
    • 0027958595 scopus 로고
    • Allelotype of uterine cancer by analysis of RFLP and microsatellite polymorphisms: Frequent loss of heterozygosity on chromosome arms 3p, 9q, 10q and 17p
    • Jones MH, Nakamura Y, Koi S, Fujimoto L, Hasumi K, Kato K. Allelotype of uterine cancer by analysis of RFLP and microsatellite polymorphisms: Frequent loss of heterozygosity on chromosome arms 3p, 9q, 10q and 17p. Genes Chromosomes Cancer 1994; 9:119-23.
    • (1994) Genes Chromosomes Cancer , vol.9 , pp. 119-123
    • Jones, M.H.1    Nakamura, Y.2    Koi, S.3    Fujimoto, L.4    Hasumi, K.5    Kato, K.6
  • 93
    • 33645676043 scopus 로고    scopus 로고
    • Comparison of DNA hypermethylation patterns in different types of uterine cancer: Cervical squamous cell carcinoma, cervical adenocarcinoma and endometrial adenocarcinoma
    • Kang S, Kim JW, Kang GH, Lee S, Park NH, Song YS, et al. Comparison of DNA hypermethylation patterns in different types of uterine cancer: cervical squamous cell carcinoma, cervical adenocarcinoma and endometrial adenocarcinoma. Int J Cancer 2006; 118: 2168-71.
    • (2006) Int J Cancer , vol.118 , pp. 2168-2171
    • Kang, S.1    Kim, J.W.2    Kang, G.H.3    Lee, S.4    Park, N.H.5    Song, Y.S.6
  • 94
    • 0036224749 scopus 로고    scopus 로고
    • The APC gene in colorectal cancer
    • Fodde R. The APC gene in colorectal cancer. Eur J Cancer 2002; 38:867-71.
    • (2002) Eur J Cancer , vol.38 , pp. 867-871
    • Fodde, R.1
  • 95
    • 0033777043 scopus 로고    scopus 로고
    • Catenins, Wnt signaling and cancer
    • Barker N, Clevers H. Catenins, Wnt signaling and cancer. Bioessays 2000; 22:961-5.
    • (2000) Bioessays , vol.22 , pp. 961-965
    • Barker, N.1    Clevers, H.2
  • 96
    • 0033784576 scopus 로고    scopus 로고
    • Mutational analysis of the CTNNB1 and APC genes in uterine endometrioid carcinoma
    • Schlosshauer PW, Pirog EC, Levine RL, Ellenson LH. Mutational analysis of the CTNNB1 and APC genes in uterine endometrioid carcinoma. Mod Pathol 2000; 13:1066-71.
    • (2000) Mod Pathol , vol.13 , pp. 1066-1071
    • Schlosshauer, P.W.1    Pirog, E.C.2    Levine, R.L.3    Ellenson, L.H.4
  • 100
    • 0036644870 scopus 로고    scopus 로고
    • Methylation of adenomatous polyposis coli in endometrial cancer occurs more frequently in tumors with microsatellite instability phenotype
    • Zysman M, Saka A, Millar A, Knight J, Chapman W, Bapat B. Methylation of adenomatous polyposis coli in endometrial cancer occurs more frequently in tumors with microsatellite instability phenotype. Cancer Res 2002; 62:3663-6.
    • (2002) Cancer Res , vol.62 , pp. 3663-3666
    • Zysman, M.1    Saka, A.2    Millar, A.3    Knight, J.4    Chapman, W.5    Bapat, B.6
  • 101
    • 50349102805 scopus 로고    scopus 로고
    • Aneuploidy predicts outcome in patients with endometrial carcinoma and is related to lack of CDH13 hypermethylation
    • Suehiro Y, Okada T, Okada T, Anno K, Okayama N, Ueno K, et al. Aneuploidy predicts outcome in patients with endometrial carcinoma and is related to lack of CDH13 hypermethylation. Clin Cancer Res 2008; 14:3354-61.
    • (2008) Clin Cancer Res , vol.14 , pp. 3354-3361
    • Suehiro, Y.1    Okada, T.2    Okada, T.3    Anno, K.4    Okayama, N.5    Ueno, K.6
  • 102
    • 0030818746 scopus 로고    scopus 로고
    • The interatcions of APC, E-cadherin and β-catenin in tumor development and progression
    • Ilyas M, Tomlinson IPM. The interatcions of APC, E-cadherin and β-catenin in tumor development and progression. J Pathol 1997; 182:128-37.
    • (1997) J Pathol , vol.182 , pp. 128-137
    • Ilyas, M.1    Tomlinson, I.P.M.2
  • 103
    • 0345269867 scopus 로고    scopus 로고
    • Abnormalities of E- and P-cadherin and catenin (beta-, gamma-catenin and p120ctn) expression in endometrial cancer and endometrial atypical hyperplasia
    • Moreno-Bueno G, Hardisson D, Sarrió D, Sánchez C, Cassia R, Prat J, et al. Abnormalities of E- and P-cadherin and catenin (beta-, gamma-catenin and p120ctn) expression in endometrial cancer and endometrial atypical hyperplasia. J Pathol 2003; 199:471-8.
    • (2003) J Pathol , vol.199 , pp. 471-478
    • Moreno-Bueno, G.1    Hardisson, D.2    Sarrió, D.3    Sánchez, C.4    Cassia, R.5    Prat, J.6
  • 104
    • 0037441617 scopus 로고    scopus 로고
    • Hypermethylation in promoter region of E-cadherin gene is associated with tumor dedifferention and myometrial invasion in endometrial carcinoma
    • Saito T, Nishimura M, Yamasaki H, Kudo R. Hypermethylation in promoter region of E-cadherin gene is associated with tumor dedifferention and myometrial invasion in endometrial carcinoma. Cancer 2003; 97:1002-9.
    • (2003) Cancer , vol.97 , pp. 1002-1009
    • Saito, T.1    Nishimura, M.2    Yamasaki, H.3    Kudo, R.4
  • 105
    • 0033557903 scopus 로고    scopus 로고
    • Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
    • Esteller M, Hamilton SR, Burger PC, Baylin SB, Herman JG. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res 1999; 59:793-7.
    • (1999) Cancer Res , vol.59 , pp. 793-797
    • Esteller, M.1    Hamilton, S.R.2    Burger, P.C.3    Baylin, S.B.4    Herman, J.G.5
  • 106
    • 13444249781 scopus 로고    scopus 로고
    • Hypermethylation in promoter region of retinoic acid receptor-beta gene and immunohistochemical findings on retinoic acid receptors in carcinogenesis of endometrium
    • Li R, Saito T, Tanaka R, Satohisa S, Adachi K, Horie M, et al. Hypermethylation in promoter region of retinoic acid receptor-beta gene and immunohistochemical findings on retinoic acid receptors in carcinogenesis of endometrium. Cancer Lett 2005; 219:33-40.
    • (2005) Cancer Lett , vol.219 , pp. 33-40
    • Li, R.1    Saito, T.2    Tanaka, R.3    Satohisa, S.4    Adachi, K.5    Horie, M.6
  • 107
    • 20144365373 scopus 로고    scopus 로고
    • Downregulation of 14-3-3sigma in ovary, prostate and endometrial carcinomas is associated with CpG island methylation
    • Mhawech P, Benz A, Cerato C, Greloz V, Assaly M, Desmond JC, et al. Downregulation of 14-3-3sigma in ovary, prostate and endometrial carcinomas is associated with CpG island methylation. Mod Pathol 2005; 18:340-8.
    • (2005) Mod Pathol , vol.18 , pp. 340-348
    • Mhawech, P.1    Benz, A.2    Cerato, C.3    Greloz, V.4    Assaly, M.5    Desmond, J.C.6
  • 108
    • 25144523351 scopus 로고    scopus 로고
    • Biallelic methylation and silencing of paternally expressed gene 3 (PEG3) in gynecologic cancer cell lines
    • Dowdy SC, Gostout BS, Shridhar V, Wu X, Smith DI, Podratz KC, et al. Biallelic methylation and silencing of paternally expressed gene 3 (PEG3) in gynecologic cancer cell lines. Gynecol Oncol 2005; 99:126-34.
    • (2005) Gynecol Oncol , vol.99 , pp. 126-134
    • Dowdy, S.C.1    Gostout, B.S.2    Shridhar, V.3    Wu, X.4    Smith, D.I.5    Podratz, K.C.6
  • 109
    • 20044396533 scopus 로고    scopus 로고
    • Promoter methylation and differential expression of pi-class glutathione S-transferase in endometrial carcinoma
    • Chan QK, Khoo US, Chan KY, Ngan HY, Li SS, Chiu PM, et al. Promoter methylation and differential expression of pi-class glutathione S-transferase in endometrial carcinoma. J Mol Diagn 2005; 7:8-16.
    • (2005) J Mol Diagn , vol.7 , pp. 8-16
    • Chan, Q.K.1    Khoo, U.S.2    Chan, K.Y.3    Ngan, H.Y.4    Li, S.S.5    Chiu, P.M.6
  • 110
    • 64249126794 scopus 로고    scopus 로고
    • Homeobox gene HOPX is epigenetically silenced in human uterine endometrial cancer and suppresses estrogen-stimulated proliferation of cancer cells by inhibiting serum response factor
    • Yamaguchi S, Asanoma K, Takao T, Kato K, Wake N. Homeobox gene HOPX is epigenetically silenced in human uterine endometrial cancer and suppresses estrogen-stimulated proliferation of cancer cells by inhibiting serum response factor. Int J Cancer 2009; 124:2577-88.
    • (2009) Int J Cancer , vol.124 , pp. 2577-2588
    • Yamaguchi, S.1    Asanoma, K.2    Takao, T.3    Kato, K.4    Wake, N.5
  • 111
    • 31544476839 scopus 로고    scopus 로고
    • Deregulation of the HOXA10 homeobox gene in endometrial carcinoma: Role in epithelial-mesenchymal transition
    • Yoshida H, Broaddus R, Cheng W, Xie S, Naora H. Deregulation of the HOXA10 homeobox gene in endometrial carcinoma: role in epithelial-mesenchymal transition. Cancer Res 2006; 66:889-97.
    • (2006) Cancer Res , vol.66 , pp. 889-897
    • Yoshida, H.1    Broaddus, R.2    Cheng, W.3    Xie, S.4    Naora, H.5
  • 112
    • 0037838407 scopus 로고    scopus 로고
    • Frequent HOXA11 and THBS2 promoter methylation, and a methylator phenotype in endometrial adenocarcinoma
    • Whitcomb BP, Mutch DG, Herzog TJ, Rader JS, Gibb RK, Goodfellow PJ. Frequent HOXA11 and THBS2 promoter methylation, and a methylator phenotype in endometrial adenocarcinoma. Clin Cancer Res 2003; 9:2277-87.
    • (2003) Clin Cancer Res , vol.9 , pp. 2277-2287
    • Whitcomb, B.P.1    Mutch, D.G.2    Herzog, T.J.3    Rader, J.S.4    Gibb, R.K.5    Goodfellow, P.J.6
  • 114
    • 65449153636 scopus 로고    scopus 로고
    • Epigenetic alteration of the metallothionein 1E gene in human endometrial carcinomas
    • Tse KY, Liu VW, Chan DW, Chiu PM, Tam KF, Chan KK, et al. Epigenetic alteration of the metallothionein 1E gene in human endometrial carcinomas. Tumour Biol 2009; 30:93-9.
    • (2009) Tumour Biol , vol.30 , pp. 93-99
    • Tse, K.Y.1    Liu, V.W.2    Chan, D.W.3    Chiu, P.M.4    Tam, K.F.5    Chan, K.K.6
  • 115
    • 0344241483 scopus 로고    scopus 로고
    • Promoter hypermethylation as an epigenetic component in Type I and Type II endometrial cancers
    • Risinger JI, Maxwell GL, Berchuck A, Barrett JC. Promoter hypermethylation as an epigenetic component in Type I and Type II endometrial cancers. Ann N Y Acad Sci 2003; 983:208-12.
    • (2003) Ann N Y Acad Sci , vol.983 , pp. 208-212
    • Risinger, J.I.1    Maxwell, G.L.2    Berchuck, A.3    Barrett, J.C.4
  • 116
    • 33746312861 scopus 로고    scopus 로고
    • Immunophenotypic diversity of endometrial adenocarcinomas: Implications for differential diagnosis
    • Reid-Nicholson M, Iyengar P, Hummer AJ, Linkov I, Asher M, Soslow RA. Immunophenotypic diversity of endometrial adenocarcinomas: implications for differential diagnosis. Mod Pathol 2006; 19:1091-100.
    • (2006) Mod Pathol , vol.19 , pp. 1091-1100
    • Reid-Nicholson, M.1    Iyengar, P.2    Hummer, A.J.3    Linkov, I.4    Asher, M.5    Soslow, R.A.6
  • 117
    • 13844255666 scopus 로고    scopus 로고
    • Opposite alterations of DNA methyltransferase gene expression in endometrioid and serous endometrial cancers
    • Xiong Y, Dowdy SC, Xue A, Shujuan J, Eberhardt NL, Podratz KC, et al. Opposite alterations of DNA methyltransferase gene expression in endometrioid and serous endometrial cancers. Gynecol Oncol 2005; 96:601-9.
    • (2005) Gynecol Oncol , vol.96 , pp. 601-609
    • Xiong, Y.1    Dowdy, S.C.2    Xue, A.3    Shujuan, J.4    Eberhardt, N.L.5    Podratz, K.C.6
  • 118
    • 33847613305 scopus 로고    scopus 로고
    • Epigenetics and cancer: Towards an evaluation of the impact of enironmental and dietary factors
    • Herceg Z. Epigenetics and cancer: towards an evaluation of the impact of enironmental and dietary factors. Mutagenesis 2007; 22:91-103.
    • (2007) Mutagenesis , vol.22 , pp. 91-103
    • Herceg, Z.1
  • 119
    • 0037370532 scopus 로고    scopus 로고
    • Biomarkers of nutrient exposure and status in one-carbon (methyl) metabolism
    • Mason JB. Biomarkers of nutrient exposure and status in one-carbon (methyl) metabolism. J Nutr 2003; 133:941-7.
    • (2003) J Nutr , vol.133 , pp. 941-947
    • Mason, J.B.1
  • 120
    • 0036328028 scopus 로고    scopus 로고
    • Folate status: Effects on pathways of colorectal carcinogenesis
    • Choi SW, Mason JB. Folate status: effects on pathways of colorectal carcinogenesis. J Nutr 2002; 132:2413-8.
    • (2002) J Nutr , vol.132 , pp. 2413-2418
    • Choi, S.W.1    Mason, J.B.2
  • 121
    • 31544467532 scopus 로고    scopus 로고
    • Nutritional epigenetics: Impact of folate deficiency on DNA methylation and colon cancer susceptibility
    • Kim YI. Nutritional epigenetics: impact of folate deficiency on DNA methylation and colon cancer susceptibility. J Nutr 2005; 135:2703-9.
    • (2005) J Nutr , vol.135 , pp. 2703-2709
    • Kim, Y.I.1
  • 122
    • 48349093183 scopus 로고    scopus 로고
    • Other one-carbon micronutrients and age modulate the effects of folate on colorectal carcinogenesis
    • Mason JB, Choi SW, Liu Z. Other one-carbon micronutrients and age modulate the effects of folate on colorectal carcinogenesis. Nutr Rev 2008; 66:15-7.
    • (2008) Nutr Rev , vol.66 , pp. 15-17
    • Mason, J.B.1    Choi, S.W.2    Liu, Z.3
  • 123
    • 33746044573 scopus 로고    scopus 로고
    • Vitamins and minerals 4: Overview of folate and the B vitamins
    • Thompson J. Vitamins and minerals 4: overview of folate and the B vitamins. Community Pract 2006; 79:197-8.
    • (2006) Community Pract , vol.79 , pp. 197-198
    • Thompson, J.1
  • 124
    • 0038605227 scopus 로고    scopus 로고
    • Folate, DNA methylation and colo-rectal cancer
    • Pufulete M, Emery PW, Sanders TA. Folate, DNA methylation and colo-rectal cancer. Proc Nutr Soc 2003; 62:437-45.
    • (2003) Proc Nutr Soc , vol.62 , pp. 437-445
    • Pufulete, M.1    Emery, P.W.2    Sanders, T.A.3
  • 125
    • 0031022797 scopus 로고    scopus 로고
    • Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene
    • Kim YI, Pogribny IP, Basnakian AG, Miller JW, Selhub J, James SJ, et al. Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene. Am J Clin Nutr 1997; 65: 46-52.
    • (1997) Am J Clin Nutr , vol.65 , pp. 46-52
    • Kim, Y.I.1    Pogribny, I.P.2    Basnakian, A.G.3    Miller, J.W.4    Selhub, J.5    James, S.J.6
  • 126
    • 0037058663 scopus 로고    scopus 로고
    • De novo methylation of the p16INK4A gene in early preneoplastic liver and tumors induced by folate/methyl deficiency in rats
    • Pogribny IP, James SJ. De novo methylation of the p16INK4A gene in early preneoplastic liver and tumors induced by folate/methyl deficiency in rats. Cancer Lett 2002; 187:69-75.
    • (2002) Cancer Lett , vol.187 , pp. 69-75
    • Pogribny, I.P.1    James, S.J.2
  • 127
    • 51849168968 scopus 로고    scopus 로고
    • Associations of dietary methyl donor intake with MLH1 promoter hypermethylation and related molecular phenotypes in sporadic colorectal cancer
    • de Vogel S, Bongaerts BW, Wouters KA, Kester AD, Schouten LJ, de Goeij AF, et al. Associations of dietary methyl donor intake with MLH1 promoter hypermethylation and related molecular phenotypes in sporadic colorectal cancer. Carcinogenesis 2008; 29:1765-73.
    • (2008) Carcinogenesis , vol.29 , pp. 1765-1773
    • de Vogel, S.1    Bongaerts, B.W.2    Wouters, K.A.3    Kester, A.D.4    Schouten, L.J.5    de Goeij, A.F.6
  • 128
    • 33747512086 scopus 로고    scopus 로고
    • Dietary folate is associated with p16INK4A methylation in head and neck squamous cell carcinoma
    • Kraunz KS, Hsiung D, McClean MD, Liu M, Osanyingbemi JO, Nelson HH, et al. Dietary folate is associated with p16INK4A methylation in head and neck squamous cell carcinoma. Int J Cancer 2006; 119:1553-7.
    • (2006) Int J Cancer , vol.119 , pp. 1553-1557
    • Kraunz, K.S.1    Hsiung, D.2    McClean, M.D.3    Liu, M.4    Osanyingbemi, J.O.5    Nelson, H.H.6
  • 129
    • 33845691410 scopus 로고    scopus 로고
    • Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer
    • Slattery ML, Curtin K, Sweeney C, Levin TR, Potter J, Wolff RK, et al. Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer. Int J Cancer 2006; 120: 656-63.
    • (2006) Int J Cancer , vol.120 , pp. 656-663
    • Slattery, M.L.1    Curtin, K.2    Sweeney, C.3    Levin, T.R.4    Potter, J.5    Wolff, R.K.6
  • 130
    • 0037731713 scopus 로고    scopus 로고
    • Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: The Netherlands cohort study on diet and cancer
    • van Engeland M, Weijenberg MP, Roemen GM, Brink M, de Bruïne AP, Goldbohm RA, et al. Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: the Netherlands cohort study on diet and cancer. Cancer Res 2003; 63:3133-7.
    • (2003) Cancer Res , vol.63 , pp. 3133-3137
    • van Engeland, M.1    Weijenberg, M.P.2    Roemen, G.M.3    Brink, M.4    de Bruïne, A.P.5    Goldbohm, R.A.6
  • 131
    • 10744228303 scopus 로고    scopus 로고
    • Methyl-group dietary intake and risk of breast cancer among African-American women: A case-control study by methylation status of the estrogen receptor alpha genes
    • Zhu K, Davidson NE, Hunter S, Yang X, Payne-Wilks K, Roland CL, et al. Methyl-group dietary intake and risk of breast cancer among African-American women: a case-control study by methylation status of the estrogen receptor alpha genes. Cancer Causes Control 2003; 14:827-36.
    • (2003) Cancer Causes Control , vol.14 , pp. 827-836
    • Zhu, K.1    Davidson, N.E.2    Hunter, S.3    Yang, X.4    Payne-Wilks, K.5    Roland, C.L.6
  • 132
    • 0033587157 scopus 로고    scopus 로고
    • Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein
    • Li Y, Upadhyay S, Bhuiyan M, Sarkar FH. Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein. Oncogene 1999; 18:3166-72.
    • (1999) Oncogene , vol.18 , pp. 3166-3172
    • Li, Y.1    Upadhyay, S.2    Bhuiyan, M.3    Sarkar, F.H.4
  • 133
  • 134
    • 0036072803 scopus 로고    scopus 로고
    • Phyto-oestrogens and cancer
    • Adlercreutz H. Phyto-oestrogens and cancer. Lancet Oncol 2002; 3:364-73.
    • (2002) Lancet Oncol , vol.3 , pp. 364-373
    • Adlercreutz, H.1
  • 135
    • 0021908716 scopus 로고
    • Naturally occurring oestrogens in foods-a review
    • Price KR, Fenwick GR. Naturally occurring oestrogens in foods-a review. Food Addit Contam 1985; 2:73-106.
    • (1985) Food Addit Contam , vol.2 , pp. 73-106
    • Price, K.R.1    Fenwick, G.R.2
  • 137
    • 26444451123 scopus 로고    scopus 로고
    • Reversal of hypermethylation and reactivation of p16INK4a, RARbeta and MGMT genes by genistein and ther isoflavones from soy
    • Fang MZ, Chen D, Sun Y, Jin Z, Christman JK, Yang CS. Reversal of hypermethylation and reactivation of p16INK4a, RARbeta and MGMT genes by genistein and ther isoflavones from soy. Clin Cancer Res 2005; 11:7034-41.
    • (2005) Clin Cancer Res , vol.11 , pp. 7034-7041
    • Fang, M.Z.1    Chen, D.2    Sun, Y.3    Jin, Z.4    Christman, J.K.5    Yang, C.S.6
  • 138
    • 38349052930 scopus 로고    scopus 로고
    • Reactivation of methylation-silenced tumor suppressor gene p16INK4a by nordihydroguaiaretic acid and its implication in G1 cell cycle arrest
    • Cui Y, Lu C, Liu L, Sun D, Yao N, Tan S, et al. Reactivation of methylation-silenced tumor suppressor gene p16INK4a by nordihydroguaiaretic acid and its implication in G1 cell cycle arrest. Life Sci 2008; 82:247-55.
    • (2008) Life Sci , vol.82 , pp. 247-255
    • Cui, Y.1    Lu, C.2    Liu, L.3    Sun, D.4    Yao, N.5    Tan, S.6
  • 139
    • 39749140314 scopus 로고    scopus 로고
    • Modulation of gene methylation by genistein or lycopene in breast cancer cells
    • King-Batoon A, Leszczynska JM, Klein CB. Modulation of gene methylation by genistein or lycopene in breast cancer cells. Environ Mol Mutagen 2008; 49:36-45.
    • (2008) Environ Mol Mutagen , vol.49 , pp. 36-45
    • King-Batoon, A.1    Leszczynska, J.M.2    Klein, C.B.3
  • 140
    • 64349112758 scopus 로고    scopus 로고
    • BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer
    • Majid S, Dar AA, Ahmad AE, Hirata H, Kawakami K, Shahryari V, et al. BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer. Carcinogenesis 2009; 30:662-70.
    • (2009) Carcinogenesis , vol.30 , pp. 662-670
    • Majid, S.1    Dar, A.A.2    Ahmad, A.E.3    Hirata, H.4    Kawakami, K.5    Shahryari, V.6
  • 141
    • 61649113446 scopus 로고    scopus 로고
    • Soy isoflavones have an antiestrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women
    • Qin W, Zhu W, Shi H, Hewett JE, Ruhlen RL, MacDonald RS, et al. Soy isoflavones have an antiestrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women. Nutr Cancer 2009; 61:238-44.
    • (2009) Nutr Cancer , vol.61 , pp. 238-244
    • Qin, W.1    Zhu, W.2    Shi, H.3    Hewett, J.E.4    Ruhlen, R.L.5    MacDonald, R.S.6
  • 142
    • 33847696486 scopus 로고    scopus 로고
    • Role of physical activity in modulating breast cancer risk as defined by APC and RASSF1A promoter hypermethylation in nonmalignant breast tissue
    • Coyle YM, Xie XJ, Lewis CM, Bu D, Milchgrub S, Euhus DM. Role of physical activity in modulating breast cancer risk as defined by APC and RASSF1A promoter hypermethylation in nonmalignant breast tissue. Cancer Epidemiol Biomarkers Prev 2007; 16:192-6.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 192-196
    • Coyle, Y.M.1    Xie, X.J.2    Lewis, C.M.3    Bu, D.4    Milchgrub, S.5    Euhus, D.M.6
  • 143
    • 0029029163 scopus 로고
    • Endometrial and ovarian cancer and oral contraceptives-findings in a large cohort study
    • Vessey MP, Painter R. Endometrial and ovarian cancer and oral contraceptives-findings in a large cohort study. Br J Cancer 1995; 71:1340-2.
    • (1995) Br J Cancer , vol.71 , pp. 1340-1342
    • Vessey, M.P.1    Painter, R.2
  • 144
    • 33748852718 scopus 로고    scopus 로고
    • Oral contraceptive and IUD use and endometrial cancer: A population-based case-control study in Shanghai, China
    • Tao MH, Xu WH, Zheng W, Zhang ZF, Gao YT, Ruan ZX, et al. Oral contraceptive and IUD use and endometrial cancer: a population-based case-control study in Shanghai, China. Int J Cancer 2006; 119:2142-7.
    • (2006) Int J Cancer , vol.119 , pp. 2142-2147
    • Tao, M.H.1    Xu, W.H.2    Zheng, W.3    Zhang, Z.F.4    Gao, Y.T.5    Ruan, Z.X.6
  • 146
    • 67449138538 scopus 로고    scopus 로고
    • DNA methyltransferase expression in the human endometrium: Downregulation by progesterone and estrogen
    • Yamagata Y, Asada H, Tamura I, Lee L, Maekawa R, Taniguchi K, et al. DNA methyltransferase expression in the human endometrium: downregulation by progesterone and estrogen. Hum Reprod 2009; 24: 1126-32.
    • (2009) Hum Reprod , vol.24 , pp. 1126-1132
    • Yamagata, Y.1    Asada, H.2    Tamura, I.3    Lee, L.4    Maekawa, R.5    Taniguchi, K.6


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