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Volumn 175, Issue 2, 2007, Pages 107-116

Down-regulation of the progesterone receptor by the methylation of progesterone receptor gene in endometrial cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE INHIBITOR; GENOMIC DNA; HISTONE DEACETYLASE INHIBITOR; MESSENGER RNA; PROGESTERONE; PROGESTERONE RECEPTOR; RNA; TRICHOSTATIN A;

EID: 34249808191     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2007.02.002     Document Type: Article
Times cited : (52)

References (39)
  • 2
    • 0242406722 scopus 로고    scopus 로고
    • Progesterone-induced apoptosis in immortalized normal and malignant human ovarian surface epithelial cells involves enhanced expression of FasL
    • Syed V., and Ho S.M. Progesterone-induced apoptosis in immortalized normal and malignant human ovarian surface epithelial cells involves enhanced expression of FasL. Oncogene 22 (2003) 6883-6890
    • (2003) Oncogene , vol.22 , pp. 6883-6890
    • Syed, V.1    Ho, S.M.2
  • 4
    • 0025239785 scopus 로고
    • Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B
    • Kastner P., Krust A., Turcotte B., Stropp U., Tora L., Gronemeyer H., and Chambon P. Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. EMBO J 9 (1990) 1603-1614
    • (1990) EMBO J , vol.9 , pp. 1603-1614
    • Kastner, P.1    Krust, A.2    Turcotte, B.3    Stropp, U.4    Tora, L.5    Gronemeyer, H.6    Chambon, P.7
  • 6
    • 0032103251 scopus 로고    scopus 로고
    • Prognostic significance of progesterone receptor immunohistochemistry in endometrial carcinoma
    • Fukuda K., Mori M., Uchiyama M., Iwai K., Iwasaka T., and Sugimori H. Prognostic significance of progesterone receptor immunohistochemistry in endometrial carcinoma. Gynecol Oncol 69 (1998) 220-225
    • (1998) Gynecol Oncol , vol.69 , pp. 220-225
    • Fukuda, K.1    Mori, M.2    Uchiyama, M.3    Iwai, K.4    Iwasaka, T.5    Sugimori, H.6
  • 7
    • 0028889324 scopus 로고
    • Progesterone receptor levels independently predict survival in endometrial adenocarcinoma
    • Nyholm H.C., Christensen I.J., and Nielsen A.L. Progesterone receptor levels independently predict survival in endometrial adenocarcinoma. Gynecol Oncol 59 (1995) 347-351
    • (1995) Gynecol Oncol , vol.59 , pp. 347-351
    • Nyholm, H.C.1    Christensen, I.J.2    Nielsen, A.L.3
  • 8
    • 0022540321 scopus 로고
    • CpG-rich islands and the function of DNA methylation
    • Bird A.P. CpG-rich islands and the function of DNA methylation. Nature 321 (1986) 209-213
    • (1986) Nature , vol.321 , pp. 209-213
    • Bird, A.P.1
  • 9
    • 0025006860 scopus 로고
    • High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines
    • Antequera F., Boyes J., and Bird A. High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines. Cell 62 (1990) 503-514
    • (1990) Cell , vol.62 , pp. 503-514
    • Antequera, F.1    Boyes, J.2    Bird, A.3
  • 10
    • 0035139039 scopus 로고    scopus 로고
    • Progesterone receptor B gene inactivation and CpG hypermethylation in human uterine endometrial cancer
    • Sasaki M., Dharia A., Oh B.R., Tanaka Y., Fujimoto S., and Dahiya R. Progesterone receptor B gene inactivation and CpG hypermethylation in human uterine endometrial cancer. Cancer Res 61 (2001) 97-102
    • (2001) Cancer Res , vol.61 , pp. 97-102
    • Sasaki, M.1    Dharia, A.2    Oh, B.R.3    Tanaka, Y.4    Fujimoto, S.5    Dahiya, R.6
  • 12
    • 0000418476 scopus 로고
    • Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine
    • Santi D.V., Norment A., and Garrett C.E. Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine. Proc Natl Acad Sci USA 81 (1984) 6993-6997
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 6993-6997
    • Santi, D.V.1    Norment, A.2    Garrett, C.E.3
  • 13
    • 16844370410 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors decrease DNA methyltransferase-3B messenger RNA stability and down-regulate de novo DNA methyltransferase activity in human endometrial cells
    • Xiong Y., Dowdy S.C., Podratz K.C., Jin F., Attewell J.R., Eberhardt N.L., and Jiang S.W. Histone deacetylase inhibitors decrease DNA methyltransferase-3B messenger RNA stability and down-regulate de novo DNA methyltransferase activity in human endometrial cells. Cancer Res 65 (2005) 2684-2689
    • (2005) Cancer Res , vol.65 , pp. 2684-2689
    • Xiong, Y.1    Dowdy, S.C.2    Podratz, K.C.3    Jin, F.4    Attewell, J.R.5    Eberhardt, N.L.6    Jiang, S.W.7
  • 14
    • 0023216891 scopus 로고
    • CpG islands in vertebrate genomes
    • Gardiner-Garden M., and Frommer M. CpG islands in vertebrate genomes. J Mol Biol 196 (1987) 261-282
    • (1987) J Mol Biol , vol.196 , pp. 261-282
    • Gardiner-Garden, M.1    Frommer, M.2
  • 15
    • 0030852948 scopus 로고    scopus 로고
    • Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction
    • Liu Y., Peterson D.A., Kimura H., and Schubert D. Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction. J Neurochem 69 (1997) 581-593
    • (1997) J Neurochem , vol.69 , pp. 581-593
    • Liu, Y.1    Peterson, D.A.2    Kimura, H.3    Schubert, D.4
  • 16
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti I., Migliorati G., Pagliacci M.C., Grignani F., and Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 139 (1991) 271-279
    • (1991) J Immunol Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 17
    • 0035056263 scopus 로고    scopus 로고
    • Molecular tools to reestablish progestin control of endometrial cancer cell proliferation
    • Dai D., Kumar N.S., Wolf D.M., and Leslie K.K. Molecular tools to reestablish progestin control of endometrial cancer cell proliferation. Am J Obstet Gynecol 184 (2001) 790-797
    • (2001) Am J Obstet Gynecol , vol.184 , pp. 790-797
    • Dai, D.1    Kumar, N.S.2    Wolf, D.M.3    Leslie, K.K.4
  • 18
    • 0023932927 scopus 로고
    • Steroid receptors and clinical outcome in patients with adenocarcinoma of the endometrium
    • Ehrlich C.E., Young P.C., Stehman F.B., Sutton G.P., and Alford W.M. Steroid receptors and clinical outcome in patients with adenocarcinoma of the endometrium. Am J Obstet Gynecol 158 (1988) 796-807
    • (1988) Am J Obstet Gynecol , vol.158 , pp. 796-807
    • Ehrlich, C.E.1    Young, P.C.2    Stehman, F.B.3    Sutton, G.P.4    Alford, W.M.5
  • 19
    • 0025266610 scopus 로고
    • Alternative chromatin structure at CpG islands
    • Tazi J., and Bird A. Alternative chromatin structure at CpG islands. Cell 60 (1990) 909-920
    • (1990) Cell , vol.60 , pp. 909-920
    • Tazi, J.1    Bird, A.2
  • 21
    • 0032490874 scopus 로고    scopus 로고
    • Demethylation of the progesterone receptor CpG island is not required for progesterone receptor gene expression
    • Ferguson A.T., Lapidus R.G., and Davidson N.E. Demethylation of the progesterone receptor CpG island is not required for progesterone receptor gene expression. Oncogene 17 (1998) 577-583
    • (1998) Oncogene , vol.17 , pp. 577-583
    • Ferguson, A.T.1    Lapidus, R.G.2    Davidson, N.E.3
  • 22
    • 0344630574 scopus 로고
    • Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene
    • Buschhausen G., Wittig B., Graessmann M., and Graessmann A. Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene. Proc Natl Acad Sci USA 84 (1987) 1177-1181
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 1177-1181
    • Buschhausen, G.1    Wittig, B.2    Graessmann, M.3    Graessmann, A.4
  • 23
    • 0027936406 scopus 로고
    • Progressive increases in the methylation status and heterochromatinization of the myoD CpG island during oncogenic transformation
    • Rideout III W.M., Eversole-Cire P., Spruck III C.H., Hustad C.M., Coetzee G.A., Gonzales F.A., and Jones P.A. Progressive increases in the methylation status and heterochromatinization of the myoD CpG island during oncogenic transformation. Mol Cell Biol 14 (1994) 6143-6152
    • (1994) Mol Cell Biol , vol.14 , pp. 6143-6152
    • Rideout III, W.M.1    Eversole-Cire, P.2    Spruck III, C.H.3    Hustad, C.M.4    Coetzee, G.A.5    Gonzales, F.A.6    Jones, P.A.7
  • 24
    • 0028106737 scopus 로고
    • Dependence of transcriptional repression on CpG methylation density
    • Hsieh C.L. Dependence of transcriptional repression on CpG methylation density. Mol Cell Biol 14 (1994) 5487-5494
    • (1994) Mol Cell Biol , vol.14 , pp. 5487-5494
    • Hsieh, C.L.1
  • 25
    • 0030793717 scopus 로고    scopus 로고
    • Stability of patch methylation and its impact in regions of transcriptional initiation and elongation
    • Hsieh C.L. Stability of patch methylation and its impact in regions of transcriptional initiation and elongation. Mol Cell Biol 17 (1997) 5897-5904
    • (1997) Mol Cell Biol , vol.17 , pp. 5897-5904
    • Hsieh, C.L.1
  • 26
    • 0027361810 scopus 로고
    • Inactive chromatin spreads from a focus of methylation
    • Kass S.U., Goddard J.P., and Adams R.L. Inactive chromatin spreads from a focus of methylation. Mol Cell Biol 13 (1993) 7372-7379
    • (1993) Mol Cell Biol , vol.13 , pp. 7372-7379
    • Kass, S.U.1    Goddard, J.P.2    Adams, R.L.3
  • 27
    • 0038732266 scopus 로고    scopus 로고
    • Polymerase chain reaction-based methods of DNA methylation analysis
    • Liu Z.J., and Maekawa M. Polymerase chain reaction-based methods of DNA methylation analysis. Anal Biochem 317 (2003) 259-265
    • (2003) Anal Biochem , vol.317 , pp. 259-265
    • Liu, Z.J.1    Maekawa, M.2
  • 28
    • 0030060367 scopus 로고    scopus 로고
    • Transcriptional repression by methylation: cooperativity between a CpG cluster in the promoter and remote CpG-rich regions
    • Hug M., Silke J., Georgiev O., Rusconi S., Schaffner W., and Matsuo K. Transcriptional repression by methylation: cooperativity between a CpG cluster in the promoter and remote CpG-rich regions. FEBS Lett 379 (1996) 251-254
    • (1996) FEBS Lett , vol.379 , pp. 251-254
    • Hug, M.1    Silke, J.2    Georgiev, O.3    Rusconi, S.4    Schaffner, W.5    Matsuo, K.6
  • 29
    • 0023701018 scopus 로고
    • Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases
    • Bestor T., Laudano A., Mattaliano R., and Ingram V. Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases. J Mol Biol 203 (1988) 971-983
    • (1988) J Mol Biol , vol.203 , pp. 971-983
    • Bestor, T.1    Laudano, A.2    Mattaliano, R.3    Ingram, V.4
  • 30
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li E., Bestor T.H., and Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69 (1992) 915-926
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 31
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano M., Bell D.W., Haber D.A., and Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99 (1999) 247-257
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 32
    • 0032706938 scopus 로고    scopus 로고
    • Dissecting de novo methylation
    • Reik W., Kelsey G., and Walter J. Dissecting de novo methylation. Nat Genet 23 (1999) 380-382
    • (1999) Nat Genet , vol.23 , pp. 380-382
    • Reik, W.1    Kelsey, G.2    Walter, J.3
  • 33
    • 0033753779 scopus 로고    scopus 로고
    • The DNA methyltransferases of mammals
    • Bestor T.H. The DNA methyltransferases of mammals. Hum Mol Genet 9 (2000) 2395-2402
    • (2000) Hum Mol Genet , vol.9 , pp. 2395-2402
    • Bestor, T.H.1
  • 34
    • 0037068379 scopus 로고    scopus 로고
    • 5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy
    • Christman J.K. 5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy. Oncogene 21 (2002) 5483-5495
    • (2002) Oncogene , vol.21 , pp. 5483-5495
    • Christman, J.K.1
  • 35
    • 33745811234 scopus 로고    scopus 로고
    • The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells
    • Li H., Rauch T., Chen Z.X., Szabo P.E., Riggs A.D., and Pfeifer G.P. The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells. J Biol Chem 281 (2006) 19489-19500
    • (2006) J Biol Chem , vol.281 , pp. 19489-19500
    • Li, H.1    Rauch, T.2    Chen, Z.X.3    Szabo, P.E.4    Riggs, A.D.5    Pfeifer, G.P.6
  • 38
    • 28044450846 scopus 로고    scopus 로고
    • The methyltransferase inhibitor 5-aza-2-deoxycytidine induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells
    • Hsi L.C., Xi X., Wu Y., and Lippman S.M. The methyltransferase inhibitor 5-aza-2-deoxycytidine induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells. Mol Cancer Ther 4 (2005) 1740-1746
    • (2005) Mol Cancer Ther , vol.4 , pp. 1740-1746
    • Hsi, L.C.1    Xi, X.2    Wu, Y.3    Lippman, S.M.4
  • 39
    • 33644688961 scopus 로고    scopus 로고
    • Induction of apoptosis by trichostatin A, a histone deacetylase inhibitor, is associated with inhibition of cyclooxygenase-2 activity in human non-small cell lung cancer cells
    • Choi Y.H. Induction of apoptosis by trichostatin A, a histone deacetylase inhibitor, is associated with inhibition of cyclooxygenase-2 activity in human non-small cell lung cancer cells. Int J Oncol 27 (2005) 473-479
    • (2005) Int J Oncol , vol.27 , pp. 473-479
    • Choi, Y.H.1


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