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Volumn 65, Issue 9, 2005, Pages 3497-3508

Role of the Ras-association domain family 1 tumor suppressor gene in human cancers

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEACETYLASE INHIBITOR; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1; RAS PROTEIN; UNCLASSIFIED DRUG;

EID: 18144411303     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-4088     Document Type: Review
Times cited : (355)

References (108)
  • 1
    • 0034327412 scopus 로고    scopus 로고
    • The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: Identification and evaluation of the resident candidate tumor suppressor genes
    • Lerman MI, Minna JD. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. Cancer Res 2000;60:6116-33.
    • (2000) Cancer Res , vol.60 , pp. 6116-6133
    • Lerman, M.I.1    Minna, J.D.2
  • 2
    • 0033918563 scopus 로고    scopus 로고
    • Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3
    • Dammann R, Li C, Yoon JH, Chin PL, Bates S, Pfeifer GP. Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3. Nat Genet 2000;25:315-9.
    • (2000) Nat Genet , vol.25 , pp. 315-319
    • Dammann, R.1    Li, C.2    Yoon, J.H.3    Chin, P.L.4    Bates, S.5    Pfeifer, G.P.6
  • 3
    • 0027240519 scopus 로고
    • Identification of the Vonhippel-Lindau disease tumor-suppressor gene
    • Latif F, Tory K, Gnarra J, et al. Identification of the Vonhippel-Lindau disease tumor-suppressor gene. Science 1993;260:1317-20.
    • (1993) Science , vol.260 , pp. 1317-1320
    • Latif, F.1    Tory, K.2    Gnarra, J.3
  • 4
    • 0015043748 scopus 로고
    • Mutation and cancer: Statistical study of retinoblastoma
    • Knudson AG. Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci U S A 1971;68:820-3.
    • (1971) Proc Natl Acad Sci U S A , vol.68 , pp. 820-823
    • Knudson, A.G.1
  • 5
    • 0037312934 scopus 로고    scopus 로고
    • Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors
    • Chen WY, Zeng XB, Carter MG, et al. Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors. Nat Genet 2003;33:197-202.
    • (2003) Nat Genet , vol.33 , pp. 197-202
    • Chen, W.Y.1    Zeng, X.B.2    Carter, M.G.3
  • 6
    • 0035932393 scopus 로고    scopus 로고
    • Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours
    • Agathanggelou A, Honorio S, Macartney DP, et al. Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours. Oncogene 2001;20:1509-18.
    • (2001) Oncogene , vol.20 , pp. 1509-1518
    • Agathanggelou, A.1    Honorio, S.2    Macartney, D.P.3
  • 7
    • 0035992419 scopus 로고    scopus 로고
    • Clinicopathological significance of epigenetic inactivation of RASSF1A at 3p21.3 in stage I lung adenocarcinoma
    • Tomizawa Y, Kohno T, Kondo H, et al. Clinicopathological significance of epigenetic inactivation of RASSF1A at 3p21.3 in stage I lung adenocarcinoma. Clin Cancer Res 2002;8:2362-8.
    • (2002) Clin Cancer Res , vol.8 , pp. 2362-2368
    • Tomizawa, Y.1    Kohno, T.2    Kondo, H.3
  • 8
    • 0037400977 scopus 로고    scopus 로고
    • Frequent hypermethylation of promoter region of RASSF1A in tumor tissues and voided urine of urinary bladder cancer patients
    • Chan MWY, Chan LW, Tang NLS, et al. Frequent hypermethylation of promoter region of RASSF1A in tumor tissues and voided urine of urinary bladder cancer patients. Int J Cancer 2003;104:611-6.
    • (2003) Int J Cancer , vol.104 , pp. 611-616
    • Chan, M.W.Y.1    Chan, L.W.2    Tang, N.L.S.3
  • 9
    • 0037431542 scopus 로고    scopus 로고
    • Hypermethylation of the tumor suppressor gene Rassf1a and frequent concomitant loss of heterozygosity at 3p21 in cervical cancers
    • Yu MY, Tong JHM, Chan PKS, et al. Hypermethylation of the tumor suppressor gene Rassf1a and frequent concomitant loss of heterozygosity at 3p21 in cervical cancers. Int J Cancer 2003;105:204-9.
    • (2003) Int J Cancer , vol.105 , pp. 204-209
    • Yu, M.Y.1    Tong, J.H.M.2    Chan, P.K.S.3
  • 10
    • 0037108984 scopus 로고    scopus 로고
    • Biallelic epigenetic inactivation of the RASSF1A tumor suppressor gene in medulloblastoma development
    • Lusher ME, Lindsey JC, Latif F, Pearson ADJ, Ellison DW, Clifford SC. Biallelic epigenetic inactivation of the RASSF1A tumor suppressor gene in medulloblastoma development. Cancer Res 2002;62:5906-11.
    • (2002) Cancer Res , vol.62 , pp. 5906-5911
    • Lusher, M.E.1    Lindsey, J.C.2    Latif, F.3    Pearson, A.D.J.4    Ellison, D.W.5    Clifford, S.C.6
  • 11
    • 0033621392 scopus 로고    scopus 로고
    • Substrate specificities and identification of putative substrates of ATM kinase family members
    • Kim ST, Lim DS, Canman CE, Kastan MB. Substrate specificities and identification of putative substrates of ATM kinase family members. J Biol Chem 1999;274:37538-43.
    • (1999) J Biol Chem , vol.274 , pp. 37538-37543
    • Kim, S.T.1    Lim, D.S.2    Canman, C.E.3    Kastan, M.B.4
  • 12
    • 18444379044 scopus 로고    scopus 로고
    • Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines
    • Harada K, Toyooka S, Maitra A, et al. Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines. Oncogene 2002;21:4345-9.
    • (2002) Oncogene , vol.21 , pp. 4345-4349
    • Harada, K.1    Toyooka, S.2    Maitra, A.3
  • 13
    • 0035884193 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of RASSF1A in human bladder carcinoma
    • Lee MG, Kim HY, Byun DS, et al. Frequent epigenetic inactivation of RASSF1A in human bladder carcinoma. Cancer Res 2001;61:6688-92.
    • (2001) Cancer Res , vol.61 , pp. 6688-6692
    • Lee, M.G.1    Kim, H.Y.2    Byun, D.S.3
  • 14
    • 0035893756 scopus 로고    scopus 로고
    • Aberrant promoter methylation profile of bladder cancer and its relationship to clinicopathological features
    • Maruyama R, Toyooka S, Toyooka KO, et al. Aberrant promoter methylation profile of bladder cancer and its relationship to clinicopathological features. Cancer Res 2001;61:8659-63.
    • (2001) Cancer Res , vol.61 , pp. 8659-8663
    • Maruyama, R.1    Toyooka, S.2    Toyooka, K.O.3
  • 15
    • 0035795676 scopus 로고    scopus 로고
    • Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression
    • Burbee DG, Forgacs E, Zochbauer-Muller S, et al. Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression. J Natl Cancer Inst 2001;93:691-9.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 691-699
    • Burbee, D.G.1    Forgacs, E.2    Zochbauer-Muller, S.3
  • 16
    • 18644383745 scopus 로고    scopus 로고
    • Frequent RASSF1A tumour suppressor gene promoter methylation in Wilms' tumour and colorectal cancer
    • Wagner KJ, Cooper WN, Grundy RG, et al. Frequent RASSF1A tumour suppressor gene promoter methylation in Wilms' tumour and colorectal cancer. Oncogene 2002;21:7277-82.
    • (2002) Oncogene , vol.21 , pp. 7277-7282
    • Wagner, K.J.1    Cooper, W.N.2    Grundy, R.G.3
  • 17
    • 5044235077 scopus 로고    scopus 로고
    • Promoter hypermethylation of DAP-kinase is associated with poor survival in primary biliary tract carcinoma patients
    • Tozawa T, Tamura G, Honda T, et al. Promoter hypermethylation of DAP-kinase is associated with poor survival in primary biliary tract carcinoma patients. Cancer Sci 2004;95:736-40.
    • (2004) Cancer Sci , vol.95 , pp. 736-740
    • Tozawa, T.1    Tamura, G.2    Honda, T.3
  • 18
    • 10744226221 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of the RASSF1A tumor suppressor gene in Hodgkin's lymphoma
    • Murray PG, Qiu GH, Fu L, et al. Frequent epigenetic inactivation of the RASSF1A tumor suppressor gene in Hodgkin's lymphoma. Oncogene 2004;23:1326-31.
    • (2004) Oncogene , vol.23 , pp. 1326-1331
    • Murray, P.G.1    Qiu, G.H.2    Fu, L.3
  • 19
    • 0036845755 scopus 로고    scopus 로고
    • Frequent loss of chromosome 3p and hypermethylation of RASSF1A in cholangiocarcinoma
    • Wong N, Li L, Tsang K, Lai PBS, To KF, Johnson PJ. Frequent loss of chromosome 3p and hypermethylation of RASSF1A in cholangiocarcinoma. J Hepatol 2002;37:633-9.
    • (2002) J Hepatol , vol.37 , pp. 633-639
    • Wong, N.1    Li, L.2    Tsang, K.3    Lai, P.B.S.4    To, K.F.5    Johnson, P.J.6
  • 20
    • 15444375859 scopus 로고    scopus 로고
    • Promoter methylation profiles of tumor suppressor genes in intrahepatic and extrahepatic cholangiocarcinoma
    • Yang B, House MG, Guo M, Herman JG, Clark DP. Promoter methylation profiles of tumor suppressor genes in intrahepatic and extrahepatic cholangiocarcinoma. Mod Pathol 2005;18:412-20.
    • (2005) Mod Pathol , vol.18 , pp. 412-420
    • Yang, B.1    House, M.G.2    Guo, M.3    Herman, J.G.4    Clark, D.P.5
  • 21
    • 0035912820 scopus 로고    scopus 로고
    • The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis
    • Dreijerink K, Braga E, Kuzmin I, et al. The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis. Proc Natl Acad Sci U S A 2001;98:7504-9.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 7504-7509
    • Dreijerink, K.1    Braga, E.2    Kuzmin, I.3
  • 22
    • 0035476868 scopus 로고    scopus 로고
    • Epigenetic inactivation of the RASSF1A 3p21.3 tumor suppressor gene in both clear cell and papillary renal cell carcinoma
    • Morrissey C, Martinez A, Zatyka M, et al. Epigenetic inactivation of the RASSF1A 3p21.3 tumor suppressor gene in both clear cell and papillary renal cell carcinoma. Cancer Res 2001;61:7277-81.
    • (2001) Cancer Res , vol.61 , pp. 7277-7281
    • Morrissey, C.1    Martinez, A.2    Zatyka, M.3
  • 23
    • 0037386938 scopus 로고    scopus 로고
    • Promoter hypermethylation of RASSF1A in esophageal squamous cell carcinoma
    • Kuroki T, Trapasso F, Yendamuri S, et al. Promoter hypermethylation of RASSF1A in esophageal squamous cell carcinoma. Clin Cancer Res 2003;9:1441-5.
    • (2003) Clin Cancer Res , vol.9 , pp. 1441-1445
    • Kuroki, T.1    Trapasso, F.2    Yendamuri, S.3
  • 24
    • 0035858992 scopus 로고    scopus 로고
    • The CpG island of the novel tumor suppressor gene RASSF1A is intensely methylated in primary small cell lung carcinomas
    • Dammann R, Takahashi T, Pfeifer GP. The CpG island of the novel tumor suppressor gene RASSF1A is intensely methylated in primary small cell lung carcinomas. Oncogene 2001;20:3563-7.
    • (2001) Oncogene , vol.20 , pp. 3563-3567
    • Dammann, R.1    Takahashi, T.2    Pfeifer, G.P.3
  • 25
    • 0038545629 scopus 로고    scopus 로고
    • RASSF1A gene inactivation in non-small cell lung cancer and its clinical implication
    • Endoh H, Yatabe Y, Shmizu S, et al. RASSF1A gene inactivation in non-small cell lung cancer and its clinical implication. Int J Cancer 2003;106:45-51.
    • (2003) Int J Cancer , vol.106 , pp. 45-51
    • Endoh, H.1    Yatabe, Y.2    Shmizu, S.3
  • 26
    • 0344873729 scopus 로고    scopus 로고
    • Epigenetic inactivation of RASSF1A candidate tumor suppressor gene at 3p21.3 in brain tumors
    • Horiguchi K, Tomizawa Y, Tosaka M, et al. Epigenetic inactivation of RASSF1A candidate tumor suppressor gene at 3p21.3 in brain tumors. Oncogene 2003;22:7862-5.
    • (2003) Oncogene , vol.22 , pp. 7862-7865
    • Horiguchi, K.1    Tomizawa, Y.2    Tosaka, M.3
  • 27
    • 0037380925 scopus 로고    scopus 로고
    • Epigenetic inactivation of RAS association domain family protein 1 (RASSF1A) in malignant cutaneous melanoma
    • Spugnardi M, Tommasi S, Dammann R, Pfeifer GP, Hoon DSB. Epigenetic inactivation of RAS association domain family protein 1 (RASSF1A) in malignant cutaneous melanoma. Cancer Res 2003;63:1639-43.
    • (2003) Cancer Res , vol.63 , pp. 1639-1643
    • Spugnardi, M.1    Tommasi, S.2    Dammann, R.3    Pfeifer, G.P.4    Hoon, D.S.B.5
  • 28
    • 0036789450 scopus 로고    scopus 로고
    • High frequency of promoter hypermethylation of RASSF1A and p16 and its relationship to aflatoxin B-1-DNA adduct levels in human hepatocellular carcinoma
    • Zhang YJ, Ahsan H, Chen Y, et al. High frequency of promoter hypermethylation of RASSF1A and p16 and its relationship to aflatoxin B-1-DNA adduct levels in human hepatocellular carcinoma. Mol Carcinog 2002;35:85-92.
    • (2002) Mol Carcinog , vol.35 , pp. 85-92
    • Zhang, Y.J.1    Ahsan, H.2    Chen, Y.3
  • 29
    • 3042707323 scopus 로고    scopus 로고
    • Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis
    • Yu J, Ni M, Xu J, et al. Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis. BMC Cancer 2002;2:29.
    • (2002) BMC Cancer , vol.2 , pp. 29
    • Yu, J.1    Ni, M.2    Xu, J.3
  • 30
    • 0036342284 scopus 로고    scopus 로고
    • Frequent 3p allele loss and epigenetic inactivation of the RASSF1A tumour suppressor gene from region 3p21.3 in head and neck squamous cell carcinoma
    • Hogg RP, Honorio S, Martinez A, et al. Frequent 3p allele loss and epigenetic inactivation of the RASSF1A tumour suppressor gene from region 3p21.3 in head and neck squamous cell carcinoma. Eur J Cancer 2002;38:1585-92.
    • (2002) Eur J Cancer , vol.38 , pp. 1585-1592
    • Hogg, R.P.1    Honorio, S.2    Martinez, A.3
  • 31
    • 0035872408 scopus 로고    scopus 로고
    • High frequency of promoter hypermethylation of RASSF1A in nasopharyngeal carcinoma
    • Lo KW, Kwong J, Hui ABY, et al. High frequency of promoter hypermethylation of RASSF1A in nasopharyngeal carcinoma. Cancer Res 2001;61:3877-81.
    • (2001) Cancer Res , vol.61 , pp. 3877-3881
    • Lo, K.W.1    Kwong, J.2    Hui, A.B.Y.3
  • 32
    • 0035829657 scopus 로고    scopus 로고
    • RASSF1A promoter region CpG island hypermethylation in phaeochromocytomas and neuroblastoma tumours
    • Astuti D, Agathanggelou A, Honorio S, et al. RASSF1A promoter region CpG island hypermethylation in phaeochromocytomas and neuroblastoma tumours. Oncogene 2001;20:7573-7.
    • (2001) Oncogene , vol.20 , pp. 7573-7577
    • Astuti, D.1    Agathanggelou, A.2    Honorio, S.3
  • 33
    • 0035888160 scopus 로고    scopus 로고
    • Hypermethylation of the CpG island of the RASSF1A gene in ovarian and renal cell carcinomas
    • Yoon JH, Damman R, Pfeifer GP. Hypermethylation of the CpG island of the RASSF1A gene in ovarian and renal cell carcinomas. Int J Cancer 2001;94:212-7.
    • (2001) Int J Cancer , vol.94 , pp. 212-217
    • Yoon, J.H.1    Damman, R.2    Pfeifer, G.P.3
  • 34
    • 0037096818 scopus 로고    scopus 로고
    • The RASSF1A tumor suppressor gene is inactivated in prostate tumors and suppresses growth of prostate carcinoma cells
    • Kuzmin I, Gillespie JW, Protopopov A, et al. The RASSF1A tumor suppressor gene is inactivated in prostate tumors and suppresses growth of prostate carcinoma cells. Cancer Res 2002;62:3498-502.
    • (2002) Cancer Res , vol.62 , pp. 3498-3502
    • Kuzmin, I.1    Gillespie, J.W.2    Protopopov, A.3
  • 36
    • 0042563143 scopus 로고    scopus 로고
    • Promoter hypermethylation of tumor suppressor and tumor-related genes in non-small cell lung cancers
    • Yanagawa N, Tamura G, Oizumi H, Takahashi N, Shimazaki Y, Motoyama T. Promoter hypermethylation of tumor suppressor and tumor-related genes in non-small cell lung cancers. Cancer Sci 2003;94:589-92.
    • (2003) Cancer Sci , vol.94 , pp. 589-592
    • Yanagawa, N.1    Tamura, G.2    Oizumi, H.3    Takahashi, N.4    Shimazaki, Y.5    Motoyama, T.6
  • 37
    • 0038418287 scopus 로고    scopus 로고
    • Hypermethylation of RASSF1A promoter is associated with the age at starting smoking and a poor prognosis in primary non-small cell lung cancer
    • Kim DH, Kim JS, Ji YI, et al. Hypermethylation of RASSF1A promoter is associated with the age at starting smoking and a poor prognosis in primary non-small cell lung cancer. Cancer Res 2003;63:3743-6.
    • (2003) Cancer Res , vol.63 , pp. 3743-3746
    • Kim, D.H.1    Kim, J.S.2    Ji, Y.I.3
  • 38
    • 0041695472 scopus 로고    scopus 로고
    • Intensive hypermethylation of the CpG island of Ras association domain family 1A in hepatitis B virus-associated hepatocellular carcinomas
    • Zhong S, Yeo W, Tang MW, Wong N, Lai PBS, Johnson PJ. Intensive hypermethylation of the CpG island of Ras association domain family 1A in hepatitis B virus-associated hepatocellular carcinomas. Clin Cancer Res 2003;9:3376-82.
    • (2003) Clin Cancer Res , vol.9 , pp. 3376-3382
    • Zhong, S.1    Yeo, W.2    Tang, M.W.3    Wong, N.4    Lai, P.B.S.5    Johnson, P.J.6
  • 39
    • 0037427808 scopus 로고    scopus 로고
    • Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer
    • Toyooka S, Maruyama R, Toyooka KO, et al. Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer. Int J Cancer 2003;103:153-60.
    • (2003) Int J Cancer , vol.103 , pp. 153-160
    • Toyooka, S.1    Maruyama, R.2    Toyooka, K.O.3
  • 40
    • 0035423037 scopus 로고    scopus 로고
    • Aberrant methylation and simian virus 40 tag sequences in malignant mesothelioma
    • Toyooka S, Pass HI, Shivapurkar N, et al. Aberrant methylation and simian virus 40 tag sequences in malignant mesothelioma. Cancer Res 2001;61:5727-30.
    • (2001) Cancer Res , vol.61 , pp. 5727-5730
    • Toyooka, S.1    Pass, H.I.2    Shivapurkar, N.3
  • 41
    • 0035300429 scopus 로고    scopus 로고
    • Hypermethylation of the CpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers
    • Dammann R, Yang G, Pfeifer GP. Hypermethylation of the CpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers. Cancer Res 2001;61:3105-9.
    • (2001) Cancer Res , vol.61 , pp. 3105-3109
    • Dammann, R.1    Yang, G.2    Pfeifer, G.P.3
  • 42
    • 2542522279 scopus 로고    scopus 로고
    • Profiling epigenetic inactivation of tumor suppressor genes in tumors and plasma from cutaneous melanoma patients
    • Hoon DSB, Spugnardi M, Kuo C, Huang SK, Morton DL, Taback B. Profiling epigenetic inactivation of tumor suppressor genes in tumors and plasma from cutaneous melanoma patients. Oncogene 2004;23:4014-22.
    • (2004) Oncogene , vol.23 , pp. 4014-4022
    • Hoon, D.S.B.1    Spugnardi, M.2    Kuo, C.3    Huang, S.K.4    Morton, D.L.5    Taback, B.6
  • 43
    • 0345392554 scopus 로고    scopus 로고
    • Alterations of RAS signalling in Chinese multiple myeloma patients: Absent BRAF and rare RAS mutations, but frequent inactivation of RASSF1A by transcriptional silencing or expression of a non-functional variant transcript
    • Ng MHL, Lau KM, Wong WS, et al. Alterations of RAS signalling in Chinese multiple myeloma patients: absent BRAF and rare RAS mutations, but frequent inactivation of RASSF1A by transcriptional silencing or expression of a non-functional variant transcript. Br J Haematol 2003;123:637-45.
    • (2003) Br J Haematol , vol.123 , pp. 637-645
    • Ng, M.H.L.1    Lau, K.M.2    Wong, W.S.3
  • 44
    • 6344229983 scopus 로고    scopus 로고
    • DNA methylation changes in multiple myeloma
    • Galm O, Wilop S, Reichelt J, et al. DNA methylation changes in multiple myeloma. Leukemia 2004;18:1687-92.
    • (2004) Leukemia , vol.18 , pp. 1687-1692
    • Galm, O.1    Wilop, S.2    Reichelt, J.3
  • 45
    • 0142053910 scopus 로고    scopus 로고
    • Aberrant methylation of multiple genes in the upper aerodigestive tract epithelium of heavy smokers
    • Zochbauer-Muller S, Lam S, Toyooka S, et al. Aberrant methylation of multiple genes in the upper aerodigestive tract epithelium of heavy smokers. Int J Cancer 2003;107:612-6.
    • (2003) Int J Cancer , vol.107 , pp. 612-616
    • Zochbauer-Muller, S.1    Lam, S.2    Toyooka, S.3
  • 46
    • 0037427083 scopus 로고    scopus 로고
    • Detection of RASSF1A aberrant promoter hypermethylation in sputum from chronic smokers and ductal carcinoma in situ from breast cancer patients
    • Honorio S, Agathanggelou A, Schuermann M, et al. Detection of RASSF1A aberrant promoter hypermethylation in sputum from chronic smokers and ductal carcinoma in situ from breast cancer patients. Oncogene 2003;22:147-50.
    • (2003) Oncogene , vol.22 , pp. 147-150
    • Honorio, S.1    Agathanggelou, A.2    Schuermann, M.3
  • 47
    • 0037780890 scopus 로고    scopus 로고
    • Evaluation of hypermethylated tumor suppressor genes as tumor markers in mouth and throat rinsing fluid, nasopharyngeal swab and peripheral blood of nasopharygeal carcinoma patient
    • Chang HW, Chan A, Kwong DLW, Wei WI, Sham JST, Yuen APW. Evaluation of hypermethylated tumor suppressor genes as tumor markers in mouth and throat rinsing fluid, nasopharyngeal swab and peripheral blood of nasopharygeal carcinoma patient. Int J Cancer 2003;105:851-5.
    • (2003) Int J Cancer , vol.105 , pp. 851-855
    • Chang, H.W.1    Chan, A.2    Kwong, D.L.W.3    Wei, W.I.4    Sham, J.S.T.5    Yuen, A.P.W.6
  • 48
    • 4644271551 scopus 로고    scopus 로고
    • Tumor cell-specific BRCA1 and RASSF1A hypermethylation in serum, plasma, and peritoneal fluid from ovarian cancer patients
    • de Caceres, II, Battagli C, Esteller M, et al. Tumor cell-specific BRCA1 and RASSF1A hypermethylation in serum, plasma, and peritoneal fluid from ovarian cancer patients. Cancer Res 2004;64:6476-81.
    • (2004) Cancer Res , vol.64 , pp. 6476-6481
    • De Caceres, I.I.1    Battagli, C.2    Esteller, M.3
  • 49
    • 1842426642 scopus 로고    scopus 로고
    • Detection of promoter hypermethylation of multiple genes in the tumor and bronchoalveolar lavage of patients with lung cancer
    • Topaloglu O, Hoque MO, Tokumaru Y, et al. Detection of promoter hypermethylation of multiple genes in the tumor and bronchoalveolar lavage of patients with lung cancer. Clin Cancer Res 2004;10:2284-8.
    • (2004) Clin Cancer Res , vol.10 , pp. 2284-2288
    • Topaloglu, O.1    Hoque, M.O.2    Tokumaru, Y.3
  • 50
    • 1642576173 scopus 로고    scopus 로고
    • Detection of breast cancer in nipple aspirate fluid by CpG island hypermethylation
    • Krassenstein R, Sauter E, Dulaimi E, et al. Detection of breast cancer in nipple aspirate fluid by CpG island hypermethylation. Clin Cancer Res 2004;10:28-32.
    • (2004) Clin Cancer Res , vol.10 , pp. 28-32
    • Krassenstein, R.1    Sauter, E.2    Dulaimi, E.3
  • 51
    • 0036184623 scopus 로고    scopus 로고
    • Aberrant promoter methylation profile of prostate cancers and its relationship to clinicopathological features
    • Maruyama R, Toyooka S, Toyooka KO, et al. Aberrant promoter methylation profile of prostate cancers and its relationship to clinicopathological features. Clin Cancer Res 2002;8:514-9.
    • (2002) Clin Cancer Res , vol.8 , pp. 514-519
    • Maruyama, R.1    Toyooka, S.2    Toyooka, K.O.3
  • 52
    • 0037015688 scopus 로고    scopus 로고
    • Frequent hypermethylation of the RASSF1A gene in prostate cancer
    • Liu LM, Yoon JH, Dammann R, Pfeifer GP. Frequent hypermethylation of the RASSF1A gene in prostate cancer. Oncogene 2002;21:6835-40.
    • (2002) Oncogene , vol.21 , pp. 6835-6840
    • Liu, L.M.1    Yoon, J.H.2    Dammann, R.3    Pfeifer, G.P.4
  • 53
    • 3442894720 scopus 로고    scopus 로고
    • Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer
    • Hoque MO, Begum S, Topaloglu O, et al. Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer. Cancer Res 2004;64:5511-7.
    • (2004) Cancer Res , vol.64 , pp. 5511-5517
    • Hoque, M.O.1    Begum, S.2    Topaloglu, O.3
  • 54
    • 0037461896 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of the RASSF1A tumour suppressor gene in testicular tumours and distinct methylation profiles of seminoma and nonseminoma testicular germ cell tumours
    • Honorio S, Agathanggelou A, Wernert N, Rothe M, Maher ER, Latif F. Frequent epigenetic inactivation of the RASSF1A tumour suppressor gene in testicular tumours and distinct methylation profiles of seminoma and nonseminoma testicular germ cell tumours. Oncogene 2003;22:461-6.
    • (2003) Oncogene , vol.22 , pp. 461-466
    • Honorio, S.1    Agathanggelou, A.2    Wernert, N.3    Rothe, M.4    Maher, E.R.5    Latif, F.6
  • 55
    • 0344081258 scopus 로고    scopus 로고
    • Characteristic promoter hypermethylation signatures in male germ cell tumors
    • Koul S, Houldsworth J, Mansukhani MM, et al. Characteristic promoter hypermethylation signatures in male germ cell tumors. Mol Cancer 2002;1:8.
    • (2002) Mol Cancer , vol.1 , pp. 8
    • Koul, S.1    Houldsworth, J.2    Mansukhani, M.M.3
  • 56
    • 2542423215 scopus 로고    scopus 로고
    • Methylated DNA collected by tampons: A new tool to detect endometrial cancer
    • Fiegl H, Gattringer C, Widschwendter A, et al. Methylated DNA collected by tampons: a new tool to detect endometrial cancer. Cancer Epidemiol Biomarkers Prev 2004;13:882-8.
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , pp. 882-888
    • Fiegl, H.1    Gattringer, C.2    Widschwendter, A.3
  • 57
    • 4344596649 scopus 로고    scopus 로고
    • The relationship between aberrant methylation and survival in non-small-cell lung cancers
    • Toyooka S, Suzuki M, Maruyama R, et al. The relationship between aberrant methylation and survival in non-small-cell lung cancers. Br J Cancer 2004;91:771-4.
    • (2004) Br J Cancer , vol.91 , pp. 771-774
    • Toyooka, S.1    Suzuki, M.2    Maruyama, R.3
  • 58
    • 0037179870 scopus 로고    scopus 로고
    • Hypomethylation and hypermethylation of DNA in Wilms tumors
    • Ehrlich M, Jiang GC, Fiala E, et al. Hypomethylation and hypermethylation of DNA in Wilms tumors. Oncogene 2002;21:6694-702.
    • (2002) Oncogene , vol.21 , pp. 6694-6702
    • Ehrlich, M.1    Jiang, G.C.2    Fiala, E.3
  • 59
    • 1642400575 scopus 로고    scopus 로고
    • Hypermethylation of FHIT as a prognostic marker in nonsmall cell lung carcinoma
    • Maruyama R, Sugio K, Yoshino L, Maehara Y, Gazdar AF. Hypermethylation of FHIT as a prognostic marker in nonsmall cell lung carcinoma. Cancer 2004;100:1472-7.
    • (2004) Cancer , vol.100 , pp. 1472-1477
    • Maruyama, R.1    Sugio, K.2    Yoshino, L.3    Maehara, Y.4    Gazdar, A.F.5
  • 60
    • 16544395214 scopus 로고    scopus 로고
    • Value of p16(INK4a) and RASSF1A promoter hypermethylation in prognosis of patients with resectable non-small cell lung cancer
    • Wang J, Lee JJ, Wang L, et al. Value of p16(INK4a) and RASSF1A promoter hypermethylation in prognosis of patients with resectable non-small cell lung cancer. Clin Cancer Res 2004;10:6119-25.
    • (2004) Clin Cancer Res , vol.10 , pp. 6119-6125
    • Wang, J.1    Lee, J.J.2    Wang, L.3
  • 61
    • 18444408077 scopus 로고    scopus 로고
    • K-ras mutations and RASSF1A promoter methylation in colorectal cancer
    • van Engeland M, Roemen G, Brink M, et al. K-ras mutations and RASSF1A promoter methylation in colorectal cancer. Oncogene 2002;21:3792-5.
    • (2002) Oncogene , vol.21 , pp. 3792-3795
    • Van Engeland, M.1    Roemen, G.2    Brink, M.3
  • 62
    • 0037534075 scopus 로고    scopus 로고
    • Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma
    • Dammann R, Schagdarsurengin U, Liu LM, et al. Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma. Oncogene 2003;22:3806-12.
    • (2003) Oncogene , vol.22 , pp. 3806-3812
    • Dammann, R.1    Schagdarsurengin, U.2    Liu, L.M.3
  • 63
    • 0042856354 scopus 로고    scopus 로고
    • RASSF1A promoter methylation and Kras2 mutations in non small cell lung cancer
    • Li J, Zhang ZQ, Dai ZY, et al. RASSF1A promoter methylation and Kras2 mutations in non small cell lung cancer. Neoplasia 2003;5:362-6.
    • (2003) Neoplasia , vol.5 , pp. 362-366
    • Li, J.1    Zhang, Z.Q.2    Dai, Z.Y.3
  • 64
    • 0141954012 scopus 로고    scopus 로고
    • Relationship of Ras association domain family 1 methylation and K-ras mutation in primary non-small cell lung cancer
    • Kim DH, Kim JS, Park JH, et al. Relationship of Ras association domain family 1 methylation and K-ras mutation in primary non-small cell lung cancer. Cancer Res 2003;63:6206-11.
    • (2003) Cancer Res , vol.63 , pp. 6206-6211
    • Kim, D.H.1    Kim, J.S.2    Park, J.H.3
  • 65
    • 1342330881 scopus 로고    scopus 로고
    • Frequent alterations of Ras signaling pathway genes in sporadic malignant melanomas
    • Reifenberger J, Knobbe CB, Sterzinger AA, et al. Frequent alterations of Ras signaling pathway genes in sporadic malignant melanomas. Int J Cancer 2004;109:377-84.
    • (2004) Int J Cancer , vol.109 , pp. 377-384
    • Reifenberger, J.1    Knobbe, C.B.2    Sterzinger, A.A.3
  • 66
    • 1642272931 scopus 로고    scopus 로고
    • Early occurrence of RASSF1A hypermethylation and its mutual exclusion with BRAF mutation in thyroid tumorigenesis
    • Xing MZ, Cohen Y, Mambo E, et al. Early occurrence of RASSF1A hypermethylation and its mutual exclusion with BRAF mutation in thyroid tumorigenesis. Cancer Res 2004;64:1664-8.
    • (2004) Cancer Res , vol.64 , pp. 1664-1668
    • Xing, M.Z.1    Cohen, Y.2    Mambo, E.3
  • 67
    • 3042742432 scopus 로고    scopus 로고
    • Involvement of ras activation in human breast cancer cell signaling, invasion, and anoikis
    • Eckert LB, Repasky GA, Ulku AS, et al. Involvement of ras activation in human breast cancer cell signaling, invasion, and anoikis. Cancer Res 2004;64:4585-92.
    • (2004) Cancer Res , vol.64 , pp. 4585-4592
    • Eckert, L.B.1    Repasky, G.A.2    Ulku, A.S.3
  • 68
    • 0344754091 scopus 로고    scopus 로고
    • Inactivation of RAS association domain family 1A gene in cervical carcinomas and the role of human papillomavirus infection
    • Kuzmin I, Liu LM, Dammann R, et al. Inactivation of RAS association domain family 1A gene in cervical carcinomas and the role of human papillomavirus infection. Cancer Res 2003;63:1888-93.
    • (2003) Cancer Res , vol.63 , pp. 1888-1893
    • Kuzmin, I.1    Liu, L.M.2    Dammann, R.3
  • 70
    • 0043026893 scopus 로고    scopus 로고
    • The RASSF1A tumor suppressor gene is commonly inactivated in adenocarcinoma of the uterine cervix
    • Cohen Y, Singer G, Lavie O, Dong SM, Beller U, Sidransky D. The RASSF1A tumor suppressor gene is commonly inactivated in adenocarcinoma of the uterine cervix. Clin Cancer Res 2003;9:2981-4.
    • (2003) Clin Cancer Res , vol.9 , pp. 2981-2984
    • Cohen, Y.1    Singer, G.2    Lavie, O.3    Dong, S.M.4    Beller, U.5    Sidransky, D.6
  • 71
    • 0036121312 scopus 로고    scopus 로고
    • Epstein-Barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma
    • Kang GH, Lee S, Kim WH, et al. Epstein-Barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma. Am J Pathol 2002;160:787-94.
    • (2002) Am J Pathol , vol.160 , pp. 787-794
    • Kang, G.H.1    Lee, S.2    Kim, W.H.3
  • 72
    • 0035476236 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of RASSF1A by aberrant promoter hypermethylation in human gastric adenocarcinoma
    • Byun DS, Lee MG, Chae KS, Ryu BG, Chi SG. Frequent epigenetic inactivation of RASSF1A by aberrant promoter hypermethylation in human gastric adenocarcinoma. Cancer Res 2001;61:7034-3.
    • (2001) Cancer Res , vol.61 , pp. 7034-7043
    • Byun, D.S.1    Lee, M.G.2    Chae, K.S.3    Ryu, B.G.4    Chi, S.G.5
  • 74
    • 0037142622 scopus 로고    scopus 로고
    • Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells
    • Toyooka S, Carbone M, Toyooka K, et al. Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells. Oncogene 2002;21:4340-4.
    • (2002) Oncogene , vol.21 , pp. 4340-4344
    • Toyooka, S.1    Carbone, M.2    Toyooka, K.3
  • 75
    • 0037434724 scopus 로고    scopus 로고
    • NORE1A, a homologue of RASSF1A tumour suppressor gene is inactivated in human cancers
    • Hesson L, Dallol A, Minna JD, Maher ER, Latif F. NORE1A, a homologue of RASSF1A tumour suppressor gene is inactivated in human cancers. Oncogene 2003;22:947-54.
    • (2003) Oncogene , vol.22 , pp. 947-954
    • Hesson, L.1    Dallol, A.2    Minna, J.D.3    Maher, E.R.4    Latif, F.5
  • 76
    • 9644253000 scopus 로고    scopus 로고
    • CpG island promoter hypermethylation of the Ras-effector gene NORE1A occurs in the context of a wild-type K-ras in lung cancer
    • Irimia M, Fraga MF, Sanchez-Cespedes M, Esteller M. CpG island promoter hypermethylation of the Ras-effector gene NORE1A occurs in the context of a wild-type K-ras in lung cancer. Oncogene 2004;23:8695-9.
    • (2004) Oncogene , vol.23 , pp. 8695-8699
    • Irimia, M.1    Fraga, M.F.2    Sanchez-Cespedes, M.3    Esteller, M.4
  • 77
    • 10744226004 scopus 로고    scopus 로고
    • The t(I;3) breakpoint-spanning involved in clear cell renal cell genes LSAMP and NOREI are carcinomas
    • Chen JD, Lui WO, Vos MD, et al. The t(I;3) breakpoint-spanning involved in clear cell renal cell genes LSAMP and NOREI are carcinomas. Cancer Cell 2003;4:405-13.
    • (2003) Cancer Cell , vol.4 , pp. 405-413
    • Chen, J.D.1    Lui, W.O.2    Vos, M.D.3
  • 78
    • 1842536844 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of RASSF1A and BLU genes located within the critical 3p21.3 region in gliomas
    • Hesson L, Bieche I, Krex D, et al. Frequent epigenetic inactivation of RASSF1A and BLU genes located within the critical 3p21.3 region in gliomas. Oncogene 2004;23:2408-19.
    • (2004) Oncogene , vol.23 , pp. 2408-2419
    • Hesson, L.1    Bieche, I.2    Krex, D.3
  • 79
    • 9244228001 scopus 로고    scopus 로고
    • RASSF4/AD037 is a potential ras effector/tumor suppressor of the RASSF family
    • Eckfeld K, Hesson L, Vos MD, Bieche I, Latif F, Clark GJ. RASSF4/AD037 is a potential ras effector/tumor suppressor of the RASSF family. Cancer Res 2004;64:8688-93.
    • (2004) Cancer Res , vol.64 , pp. 8688-8693
    • Eckfeld, K.1    Hesson, L.2    Vos, M.D.3    Bieche, I.4    Latif, F.5    Clark, G.J.6
  • 80
    • 4544242851 scopus 로고    scopus 로고
    • Induction of DNA methylation and gene silencing by short interfering RNAs in human cells
    • Kawasaki H, Taira K. Induction of DNA methylation and gene silencing by short interfering RNAs in human cells. Nature 2004;431:211-7.
    • (2004) Nature , vol.431 , pp. 211-217
    • Kawasaki, H.1    Taira, K.2
  • 81
    • 4444364003 scopus 로고    scopus 로고
    • Antisense intronic non-coding RNA levels correlate to the degree of tumor differentiation in prostate cancer
    • Reis EM, Nakaya HI, Louro R, et al. Antisense intronic non-coding RNA levels correlate to the degree of tumor differentiation in prostate cancer. Oncogene 2004;23:6684-92.
    • (2004) Oncogene , vol.23 , pp. 6684-6692
    • Reis, E.M.1    Nakaya, H.I.2    Louro, R.3
  • 82
    • 4043131815 scopus 로고    scopus 로고
    • Inactivation of RASSF1C during in vivo tumor growth identifies it as a tumor suppressor gene
    • Li JF, Wang FL, Protopopov A. et al. Inactivation of RASSF1C during in vivo tumor growth identifies it as a tumor suppressor gene. Oncogene 2004;23:5941-9.
    • (2004) Oncogene , vol.23 , pp. 5941-5949
    • Li, J.F.1    Wang, F.L.2    Protopopov, A.3
  • 83
    • 0036264815 scopus 로고    scopus 로고
    • The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation
    • Shivakumar L, Minna J, Sakamaki T, Pestell R, White MA. The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation. Mol Cell Biol 2002;22:4309-18.
    • (2002) Mol Cell Biol , vol.22 , pp. 4309-4318
    • Shivakumar, L.1    Minna, J.2    Sakamaki, T.3    Pestell, R.4    White, M.A.5
  • 84
    • 3042675106 scopus 로고    scopus 로고
    • RASSF1A interacts with microtubule-associated proteins and modulates microtubule dynamics
    • Dallol A, Agathanggelou A, Fenton SL, et al. RASSF1A interacts with microtubule-associated proteins and modulates microtubule dynamics. Cancer Res 2004;64:4112-6.
    • (2004) Cancer Res , vol.64 , pp. 4112-4116
    • Dallol, A.1    Agathanggelou, A.2    Fenton, S.L.3
  • 85
    • 2442482316 scopus 로고    scopus 로고
    • RASSF1A is a target tumor suppressor from 3p21.3 in nasopharyngeal carcinoma
    • Chow LSN, Lo KW, Kwong J, et al. RASSF1A is a target tumor suppressor from 3p21.3 in nasopharyngeal carcinoma. Int J Cancer 2004;109:839-47.
    • (2004) Int J Cancer , vol.109 , pp. 839-847
    • Chow, L.S.N.1    Lo, K.W.2    Kwong, J.3
  • 86
    • 0034680870 scopus 로고    scopus 로고
    • Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosis
    • Vos MD, Ellis CA, Bell A, Birrer MJ, Clark GJ. Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosis. J Biol Chem 2000;275:35669-72.
    • (2000) J Biol Chem , vol.275 , pp. 35669-35672
    • Vos, M.D.1    Ellis, C.A.2    Bell, A.3    Birrer, M.J.4    Clark, G.J.5
  • 87
    • 0141705435 scopus 로고    scopus 로고
    • Identification of novel gene expression targets for the Ras association domain family I (RASSFIA) tumor suppressor gene in non-small cell lung cancer and neuroblastoma
    • Agathanggelou A, Bleche I, Ahmed-Choudhury J, et al. Identification of novel gene expression targets for the Ras association domain family I (RASSFIA) tumor suppressor gene in non-small cell lung cancer and neuroblastoma. Cancer Res 2003;63:5344-51.
    • (2003) Cancer Res , vol.63 , pp. 5344-5351
    • Agathanggelou, A.1    Bleche, I.2    Ahmed-Choudhury, J.3
  • 88
    • 0037019185 scopus 로고    scopus 로고
    • Cre-loxP chromosome engineering of a targeted deletion in the mouse corresponding to the 3p21.3 region of homozygous loss in human tumours
    • Smith AJH, Xian J, Richardson M, Johnstone KA, Rabbitts PH, Cre-loxP chromosome engineering of a targeted deletion in the mouse corresponding to the 3p21.3 region of homozygous loss in human tumours. Oncogene 2002;21:4521-9.
    • (2002) Oncogene , vol.21 , pp. 4521-4529
    • Smith, A.J.H.1    Xian, J.2    Richardson, M.3    Johnstone, K.A.4    Rabbitts, P.H.5
  • 89
    • 0344825077 scopus 로고    scopus 로고
    • Control of microtubule stability by the RASSF1A tumor suppressor
    • Liu LM, Tommasi S, Lee DH, Dammann R, Pfeifer GP. Control of microtubule stability by the RASSF1A tumor suppressor. Oncogene 2003;22:8125-36.
    • (2003) Oncogene , vol.22 , pp. 8125-8136
    • Liu, L.M.1    Tommasi, S.2    Lee, D.H.3    Dammann, R.4    Pfeifer, G.P.5
  • 90
    • 3042655534 scopus 로고    scopus 로고
    • A role for the RASSF1A tumor suppressor in the regulation of tubulin polymerization and genomic stability
    • CO. Vos MD, Martinez, A, Elam C, et al. A role for the RASSF1A tumor suppressor in the regulation of tubulin polymerization and genomic stability. Cancer Res 2004;64:4244-50.
    • (2004) Cancer Res , vol.64 , pp. 4244-4250
    • Vos, M.D.1    Martinez, A.2    Elam, C.3
  • 92
    • 1642602695 scopus 로고    scopus 로고
    • The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
    • Song MS, Song SJ, Ayad NG, et al. The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex. Nat Cell Biol 2004;6:129-37.
    • (2004) Nat Cell Biol , vol.6 , pp. 129-137
    • Song, M.S.1    Song, S.J.2    Ayad, N.G.3
  • 93
    • 0037982694 scopus 로고    scopus 로고
    • Novel complex integrating mitochondria and the microtubular cytoskeleton with chromosome remodeling and tumor suppressor RASSF1 deduced by in silico homology analysis, interaction cloning in yeast, and colocalization in cultured cells
    • Liu LY, Vo A, Liu GQ, McKeehan WL. Novel complex integrating mitochondria and the microtubular cytoskeleton with chromosome remodeling and tumor suppressor RASSF1 deduced by in silico homology analysis, interaction cloning in yeast, and colocalization in cultured cells. In vitro Cell Dev Biol Anim 2002;38:582-94.
    • (2002) In Vitro Cell Dev Biol Anim , vol.38 , pp. 582-594
    • Liu, L.Y.1    Vo, A.2    Liu, G.Q.3    McKeehan, W.L.4
  • 94
    • 85047696339 scopus 로고    scopus 로고
    • The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1
    • Ortiz-Vega S, Khokhlatchev A, Nedwidek M, et al. The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1. Oncogene 2002;21:1381-90.
    • (2002) Oncogene , vol.21 , pp. 1381-1390
    • Ortiz-Vega, S.1    Khokhlatchev, A.2    Nedwidek, M.3
  • 95
    • 0037133034 scopus 로고    scopus 로고
    • Identification of a novel Ras-regulated proapoptotic pathway
    • Khokhlatchev A, Rahizadeh S, Xavier R, et al. Identification of a novel Ras-regulated proapoptotic pathway. Curr Biol 2002;12:253-65.
    • (2002) Curr Biol , vol.12 , pp. 253-265
    • Khokhlatchev, A.1    Rahizadeh, S.2    Xavier, R.3
  • 96
    • 0032522704 scopus 로고    scopus 로고
    • Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1
    • Graves JD, Gotoh Y, Draves KE, et al. Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1. EMBO J 1998;17:2224-34.
    • (1998) EMBO J , vol.17 , pp. 2224-2234
    • Graves, J.D.1    Gotoh, Y.2    Draves, K.E.3
  • 97
    • 3242794878 scopus 로고    scopus 로고
    • Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras
    • Praskova M, Khoklatchev A, Ortiz-Vega S, Avruch J. Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras. Biochem J 2004;381:453-62.
    • (2004) Biochem J , vol.381 , pp. 453-462
    • Praskova, M.1    Khoklatchev, A.2    Ortiz-Vega, S.3    Avruch, J.4
  • 98
    • 3142710380 scopus 로고    scopus 로고
    • The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death
    • Rabizadeh S, Xavier RJ, Ishiguro K, et al. The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death. J Biol Chem 2004;279:29247-54.
    • (2004) J Biol Chem , vol.279 , pp. 29247-29254
    • Rabizadeh, S.1    Xavier, R.J.2    Ishiguro, K.3
  • 99
    • 0037048324 scopus 로고    scopus 로고
    • Control of the centriole and centrosome cycles by ubiquitination enzymes
    • Hansen DV, Hsu JY, Kaiser BK, Jackson PK, Eldridge AG. Control of the centriole and centrosome cycles by ubiquitination enzymes. Oncogene 2002;21:6209-21.
    • (2002) Oncogene , vol.21 , pp. 6209-6221
    • Hansen, D.V.1    Hsu, J.Y.2    Kaiser, B.K.3    Jackson, P.K.4    Eldridge, A.G.5
  • 100
    • 0034745055 scopus 로고    scopus 로고
    • Cyclin A is a mediator of p120(E4F)-dependent cell cycle arrest in G(I)
    • Fajas L, Paul C, Vie A, et al. Cyclin A is a mediator of p120(E4F)-dependent cell cycle arrest in G(I). Mol Cell Biol 2001;21:2956-66.
    • (2001) Mol Cell Biol , vol.21 , pp. 2956-2966
    • Fajas, L.1    Paul, C.2    Vie, A.3
  • 101
    • 9144262332 scopus 로고    scopus 로고
    • Identification of the E1A-regulated transcription factor p120(E4F) as an interacting partner of the RASSF1A candidate tumor suppressor gene
    • Fenton SL, Dallol A, Agathanggelou A, et al. Identification of the E1A-regulated transcription factor p120(E4F) as an interacting partner of the RASSF1A candidate tumor suppressor gene. Cancer Res 2004;64:102-7.
    • (2004) Cancer Res , vol.64 , pp. 102-107
    • Fenton, S.L.1    Dallol, A.2    Agathanggelou, A.3
  • 102
    • 3843098291 scopus 로고    scopus 로고
    • 2+ pump 4b and the proapoptotic tumor suppressor Ras-associated factor 1 (RASSF1)
    • 2+ pump 4b and the proapoptotic tumor suppressor Ras-associated factor 1 (RASSF1). J Biol Chem 2004;279:31318-28.
    • (2004) J Biol Chem , vol.279 , pp. 31318-31328
    • Armesilla, A.L.1    Williams, J.C.2    Buch, M.H.3
  • 103
    • 0032489384 scopus 로고    scopus 로고
    • Identification of Nore1 as a potential Ras effector
    • Vavvas D, Li X, Avruch J, Zhang XF. Identification of Norel as a potential Ras effector. J Biol Chem 1998;273:5439-42.
    • (1998) J Biol Chem , vol.273 , pp. 5439-5442
    • Vavvas, D.1    Li, X.2    Avruch, J.3    Zhang, X.F.4
  • 104
    • 0038497974 scopus 로고    scopus 로고
    • The pro-apoptotic Ras effector Norel may serve as a Ras- regulated tumor suppressor in the lung
    • Vos MD, Martinez A, Ellis CA, Vallecorsa T, Clark GJ. The pro-apoptotic Ras effector Norel may serve as a Ras- regulated tumor suppressor in the lung. J Biol Chem 2003;278:21938-43.
    • (2003) J Biol Chem , vol.278 , pp. 21938-21943
    • Vos, M.D.1    Martinez, A.2    Ellis, C.A.3    Vallecorsa, T.4    Clark, G.J.5
  • 105
    • 2442708891 scopus 로고    scopus 로고
    • Nore1 inhibits tumor cell growth independent of Ras or the MST1/2 kinases
    • Aoyama Y, Avruch J, Zhang XF. Nore1 inhibits tumor cell growth independent of Ras or the MST1/2 kinases. Oncogene 2004;23:3426-33.
    • (2004) Oncogene , vol.23 , pp. 3426-3433
    • Aoyama, Y.1    Avruch, J.2    Zhang, X.F.3
  • 106
    • 0035130112 scopus 로고    scopus 로고
    • Isolation and molecular characterization of rasfadin, a novel gene in the vicinity of the bovine prion gene
    • Comincini S, Castiglioni BM, Foti GM, Del Vecchio I, Ferretti L. Isolation and molecular characterization of rasfadin, a novel gene in the vicinity of the bovine prion gene. Mamm Genome 2001;12:150-6.
    • (2001) Mamm Genome , vol.12 , pp. 150-156
    • Comincini, S.1    Castiglioni, B.M.2    Foti, G.M.3    Del Vecchio, I.4    Ferretti, L.5
  • 107
    • 0344391946 scopus 로고    scopus 로고
    • Gene expression profiles in human cells submitted to genotoxic stress
    • Sakamoto-Hojo ET, Mello SS, Pereira E, et al. Gene expression profiles in human cells submitted to genotoxic stress. Mutat Res 2003;544:403-13.
    • (2003) Mutat Res , vol.544 , pp. 403-413
    • Sakamoto-Hojo, E.T.1    Mello, S.S.2    Pereira, E.3
  • 108


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