-
1
-
-
0024026298
-
Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.
-
DeFronzo RA. Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM. Diabetes 1988, 37:667-687..
-
(1988)
Diabetes
, vol.37
-
-
DeFronzo, R.A.1
-
2
-
-
0024213009
-
Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes.
-
Clark A, Wells CA, Buley ID. Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes. Diabetes Res 1988, 9:151-159..
-
(1988)
Diabetes Res
, vol.9
-
-
Clark, A.1
Wells, C.A.2
Buley, I.D.3
-
3
-
-
0021777067
-
Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited.
-
Kloppel G, Lohr M, Habich K. Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited. Surv Synth Pathol Res 1985, 4:110-125..
-
(1985)
Surv Synth Pathol Res
, vol.4
-
-
Kloppel, G.1
Lohr, M.2
Habich, K.3
-
4
-
-
0019996086
-
Quantitation of endocrine cell content in the pancreas of nondiabetic and diabetic humans.
-
Stefan Y, Orci L, Malaisse-Lagae F. Quantitation of endocrine cell content in the pancreas of nondiabetic and diabetic humans. Diabetes 1982, 31:694-700..
-
(1982)
Diabetes
, vol.31
-
-
Stefan, Y.1
Orci, L.2
Malaisse-Lagae, F.3
-
5
-
-
0037219411
-
β-Cell deficit and increased β-cell apoptosis in humans with type 2 diabetes.
-
Butler AE, Janson J, Bonner-Weir S. β-Cell deficit and increased β-cell apoptosis in humans with type 2 diabetes. Diabetes 2003, 52:102-110..
-
(2003)
Diabetes
, vol.52
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
-
6
-
-
0038707331
-
Selective β-cell loss and α-cell expansion in patients with type 2 diabetes mellitus in Korea.
-
Yoon KH, Ko SH, Cho JH. Selective β-cell loss and α-cell expansion in patients with type 2 diabetes mellitus in Korea. J Clin Endocrinol Metab 2003, 88:2300-2308..
-
(2003)
J Clin Endocrinol Metab
, vol.88
-
-
Yoon, K.H.1
Ko, S.H.2
Cho, J.H.3
-
7
-
-
0032999544
-
Neogenesis vs. apoptosis as main components of pancreatic β-cell mass changes in glucose-infused normal and mildly diabetic adult rats.
-
Bernard C, Berthault M-F, Saulnier C. Neogenesis vs. apoptosis as main components of pancreatic β-cell mass changes in glucose-infused normal and mildly diabetic adult rats. FASEB J 1999, 13:1195-1205..
-
(1999)
FASEB J
, vol.13
-
-
Bernard, C.1
Berthault, M.-.F.2
Saulnier, C.3
-
8
-
-
0031913829
-
Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat.
-
Pick A, Clark J, Kubstrup C. Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat. Diabetes 1998, 47:358-364..
-
(1998)
Diabetes
, vol.47
-
-
Pick, A.1
Clark, J.2
Kubstrup, C.3
-
10
-
-
0042822112
-
Increased β-cell apoptosis prevents adaptive increase in β-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid.
-
Butler AE, Janson J, Soeller WC. Increased β-cell apoptosis prevents adaptive increase in β-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid. Diabetes 2003, 52:2304-2314..
-
(2003)
Diabetes
, vol.52
-
-
Butler, A.E.1
Janson, J.2
Soeller, W.C.3
-
12
-
-
0035128535
-
Role of apoptosis in pancreatic beta-cell death in diabetes.
-
Chandra J, Zhivotovsky B, Zaitsev S. Role of apoptosis in pancreatic beta-cell death in diabetes. Diabetes 2001, 50:S44-S47..
-
(2001)
Diabetes
, vol.50
-
-
Chandra, J.1
Zhivotovsky, B.2
Zaitsev, S.3
-
13
-
-
0036910731
-
Apoptosis in the beta cells: cause or consequence of insulin secretion defect in diabetes?
-
Sesti G. Apoptosis in the beta cells: cause or consequence of insulin secretion defect in diabetes? Ann Med 2002, 34:444-450..
-
(2002)
Ann Med
, vol.34
-
-
Sesti, G.1
-
14
-
-
0242609973
-
Impact of endoplasmic reticulum stress pathway on pancreatic β-cells and diabetes mellitus.
-
Araki E, Oyadomari S, Mori M. Impact of endoplasmic reticulum stress pathway on pancreatic β-cells and diabetes mellitus. Exp Biol Med 2003, 228:1213-1217..
-
(2003)
Exp Biol Med
, vol.228
-
-
Araki, E.1
Oyadomari, S.2
Mori, M.3
-
15
-
-
4744355191
-
Death effectors of β-cell apoptosis in type 1 diabetes.
-
Lee M-S, Chang I, Kim S. Death effectors of β-cell apoptosis in type 1 diabetes. Mol Genet Metab 2004, 83:82-92..
-
(2004)
Mol Genet Metab
, vol.83
-
-
Lee, M.-.S.1
Chang, I.2
Kim, S.3
-
16
-
-
0035856952
-
Beta-cell death during progression to diabetes.
-
Mathis D, Vence L, Benoist C. Beta-cell death during progression to diabetes. Nature 2001, 414:792-798..
-
(2001)
Nature
, vol.414
-
-
Mathis, D.1
Vence, L.2
Benoist, C.3
-
17
-
-
0035845568
-
Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway.
-
Oyadomari S, Takeda K, Takiguchi M. Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway. Proc Natl Acad Sci U S A 2001, 98:10845-10850..
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
-
-
Oyadomari, S.1
Takeda, K.2
Takiguchi, M.3
-
18
-
-
0036260052
-
Na/Ca exchanger overexpression induces endoplasmic reticulum-related apoptosis and caspase-12 activation in insulin-releasing BRIN-BD11 cells.
-
Diaz-Horta O, Kamagate A, Herchuelz A. Na/Ca exchanger overexpression induces endoplasmic reticulum-related apoptosis and caspase-12 activation in insulin-releasing BRIN-BD11 cells. Diabetes 2002, 51:1815-1824..
-
(2002)
Diabetes
, vol.51
-
-
Diaz-Horta, O.1
Kamagate, A.2
Herchuelz, A.3
-
19
-
-
0034610792
-
Caspases find a new place to hide.
-
Mehmet H. Caspases find a new place to hide. Nature 2000, 403:29-30..
-
(2000)
Nature
, vol.403
-
-
Mehmet, H.1
-
20
-
-
0034476896
-
An endoplasmic reticulum-specific stress-activated caspase (caspase-12) is implicated in the apoptosis of A549 epithelial cells by respiratory syncytial virus.
-
Bitko V, Barik S. An endoplasmic reticulum-specific stress-activated caspase (caspase-12) is implicated in the apoptosis of A549 epithelial cells by respiratory syncytial virus. J Cell Biochem 2001, 80:441-454..
-
(2001)
J Cell Biochem
, vol.80
-
-
Bitko, V.1
Barik, S.2
-
21
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta.
-
Nakagawa T, Zhu H, Morishima N. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 2000, 403:98-103..
-
(2000)
Nature
, vol.403
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
-
22
-
-
0037077254
-
Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway.
-
Rao RV, Castro-Obregon S, Frankowski H. Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway. J Biol Chem 2002, 277:21836-21842..
-
(2002)
J Biol Chem
, vol.277
-
-
Rao, R.V.1
Castro-Obregon, S.2
Frankowski, H.3
-
23
-
-
70549084746
-
Endoplasmic reticulum stress in disease: mechanisms and therapeutic opportunities.
-
Hosoi T, Ozawa K. Endoplasmic reticulum stress in disease: mechanisms and therapeutic opportunities. Clin Sci 2009, 118:19-29..
-
(2009)
Clin Sci
, vol.118
-
-
Hosoi, T.1
Ozawa, K.2
-
24
-
-
0036022403
-
Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells.
-
Oyadomari S, Araki E, Mori M. Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells. Apoptosis 2002, 7:335-345..
-
(2002)
Apoptosis
, vol.7
-
-
Oyadomari, S.1
Araki, E.2
Mori, M.3
-
25
-
-
0036175128
-
Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes.
-
Oyadomari S, Koizumi A, Takeda K. Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes. J Clin Invest 2002, 109:525-532..
-
(2002)
J Clin Invest
, vol.109
-
-
Oyadomari, S.1
Koizumi, A.2
Takeda, K.3
-
26
-
-
1942475176
-
The role of endoplasmic reticulum stress in nonimmune diabetes: NOD.k iHEL, a novel model of β-cell death.
-
Socha L, Silva D, Lesage S. The role of endoplasmic reticulum stress in nonimmune diabetes: NOD.k iHEL, a novel model of β-cell death. Ann N Y Acad Sci 2003, 1005:178-183..
-
(2003)
Ann N Y Acad Sci
, vol.1005
-
-
Socha, L.1
Silva, D.2
Lesage, S.3
-
27
-
-
0034968330
-
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival.
-
Harding HP, Zeng H, Zhang Y. Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival. Mol Cell 2001, 7:1153-1163..
-
(2001)
Mol Cell
, vol.7
-
-
Harding, H.P.1
Zeng, H.2
Zhang, Y.3
-
28
-
-
0034425698
-
EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome.
-
Delepine M, Nicolino M, Barrett T. EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome. Nat Genet 2000, 25:406-409..
-
(2000)
Nat Genet
, vol.25
-
-
Delepine, M.1
Nicolino, M.2
Barrett, T.3
-
29
-
-
0035283066
-
WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain.
-
Takeda K, Inoue H, Tanizawa Y. WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain. Hum Mol Genet 2001, 10:477-484..
-
(2001)
Hum Mol Genet
, vol.10
-
-
Takeda, K.1
Inoue, H.2
Tanizawa, Y.3
-
30
-
-
0037288692
-
Endoplasmic reticulum stress and diabetes mellitus.
-
Araki E, Oyadomari S, Mori M. Endoplasmic reticulum stress and diabetes mellitus. Intern Med 2003, 42:7-14..
-
(2003)
Intern Med
, vol.42
-
-
Araki, E.1
Oyadomari, S.2
Mori, M.3
-
31
-
-
19944432792
-
Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic β-cells.
-
Cardozo AK, Ortis F, Storling J. Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic β-cells. Diabetes 2005, 54:452-461..
-
(2005)
Diabetes
, vol.54
-
-
Cardozo, A.K.1
Ortis, F.2
Storling, J.3
-
32
-
-
28244435870
-
WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic β-cells.
-
Fonseca SG, Fukuma M, Lipson KL. WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic β-cells. J Biol Chem 2005, 280:39609-39615..
-
(2005)
J Biol Chem
, vol.280
-
-
Fonseca, S.G.1
Fukuma, M.2
Lipson, K.L.3
-
33
-
-
22744444016
-
Endoplasmic reticulum stress induces WFS1 gene expression in pancreatic β-cells via transcriptional activation.
-
Ueda K, Kawano J, Takeda K. Endoplasmic reticulum stress induces WFS1 gene expression in pancreatic β-cells via transcriptional activation. Eur J Endocrinol 2005, 153:167-176..
-
(2005)
Eur J Endocrinol
, vol.153
-
-
Ueda, K.1
Kawano, J.2
Takeda, K.3
-
34
-
-
33745202552
-
WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic β-cells.
-
Yamada T, Ishihara H, Tamura A. WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic β-cells. Hum Mol Genet 2006, 15:1600-1609..
-
(2006)
Hum Mol Genet
, vol.15
-
-
Yamada, T.1
Ishihara, H.2
Tamura, A.3
-
35
-
-
0345465663
-
Integration of endoplasmic reticulum signaling in health and disease.
-
Aridor M, Balch WE. Integration of endoplasmic reticulum signaling in health and disease. Nat Med 1999, 5:745-751..
-
(1999)
Nat Med
, vol.5
-
-
Aridor, M.1
Balch, W.E.2
-
36
-
-
0036856008
-
Translational control in the endoplasmic reticulum stress response.
-
Ron D. Translational control in the endoplasmic reticulum stress response. J Clin Invest 2002, 110:1383-1388..
-
(2002)
J Clin Invest
, vol.110
-
-
Ron, D.1
-
37
-
-
0036895383
-
Endoplasmic reticulum stress and the development of diabetes: a review.
-
Harding HP, Ron D. Endoplasmic reticulum stress and the development of diabetes: a review. Diabetes 2002, 51:S455-S461..
-
(2002)
Diabetes
, vol.51
-
-
Harding, H.P.1
Ron, D.2
-
38
-
-
0030931876
-
Caspases: the executioners of apoptosis.
-
Cohen GM. Caspases: the executioners of apoptosis. Biochem J 1997, 326:1-16..
-
(1997)
Biochem J
, vol.326
-
-
Cohen, G.M.1
-
39
-
-
0031733287
-
Mass spectrometric evidence that agents that cause loss of Ca2+ from intracellular compartments induce hydrolysis of arachidonic acid from pancreatic islet membrane phospholipids by a mechanism that does not require a rise in cytosolic Ca2+ concentration.
-
Nowatzke W, Ramanadham S, Ma Z. Mass spectrometric evidence that agents that cause loss of Ca2+ from intracellular compartments induce hydrolysis of arachidonic acid from pancreatic islet membrane phospholipids by a mechanism that does not require a rise in cytosolic Ca2+ concentration. Endocrinology 1998, 139:4073-4085..
-
(1998)
Endocrinology
, vol.139
-
-
Nowatzke, W.1
Ramanadham, S.2
Ma, Z.3
-
41
-
-
0014277263
-
Quantitative distribution of phospholipids in neurons and glial cells isolated from rat cerebral cortex.
-
Freysz L, Bieth R, Judes C. Quantitative distribution of phospholipids in neurons and glial cells isolated from rat cerebral cortex. J Neurochem 1968, 15:307-313..
-
(1968)
J Neurochem
, vol.15
-
-
Freysz, L.1
Bieth, R.2
Judes, C.3
-
42
-
-
0027752299
-
Mass spectrometric characterization of arachidonate-containing plasmalogens in human pancreatic islets and in rat islet beta-cells and subcellular membranes.
-
Ramanadham S, Bohrer A, Gross RW. Mass spectrometric characterization of arachidonate-containing plasmalogens in human pancreatic islets and in rat islet beta-cells and subcellular membranes. Biochemistry 1993, 32:13499-13509..
-
(1993)
Biochemistry
, vol.32
-
-
Ramanadham, S.1
Bohrer, A.2
Gross, R.W.3
-
43
-
-
0027231193
-
Mass spectrometric identification and quantitation of arachidonate-containing phospholipids in pancreatic islets: prominence of plasmenylethanolamine molecular species.
-
Ramanadham S, Bohrer A, Mueller M. Mass spectrometric identification and quantitation of arachidonate-containing phospholipids in pancreatic islets: prominence of plasmenylethanolamine molecular species. Biochemistry 1993, 32:5339-5351..
-
(1993)
Biochemistry
, vol.32
-
-
Ramanadham, S.1
Bohrer, A.2
Mueller, M.3
-
45
-
-
77953285560
-
Group VIA Ca2+-independent phospholipase A2 (iPLA2β) and its role in β-cell programmed cell death.
-
Lei X, Barbour SE, Ramanadham S. Group VIA Ca2+-independent phospholipase A2 (iPLA2β) and its role in β-cell programmed cell death. Biochimie 2010, 92:627-637..
-
(2010)
Biochimie
, vol.92
-
-
Lei, X.1
Barbour, S.E.2
Ramanadham, S.3
-
46
-
-
0030999048
-
Pancreatic islets express a Ca2+-independent phospholipase A2 enzyme that contains a repeated structural motif homologous to the integral membrane protein binding domain of ankyrin.
-
Ma Z, Ramanadham S, Kempe K. Pancreatic islets express a Ca2+-independent phospholipase A2 enzyme that contains a repeated structural motif homologous to the integral membrane protein binding domain of ankyrin. J Biol Chem 1997, 272:11118-11127..
-
(1997)
J Biol Chem
, vol.272
-
-
Ma, Z.1
Ramanadham, S.2
Kempe, K.3
-
47
-
-
13544261554
-
The expression and function of a group VIA calcium-independent phospholipase A2 (iPLA2β) in beta-cells.
-
Turk J, Ramanadham S. The expression and function of a group VIA calcium-independent phospholipase A2 (iPLA2β) in beta-cells. Can J Physiol Pharmacol 2004, 82:824-832..
-
(2004)
Can J Physiol Pharmacol
, vol.82
-
-
Turk, J.1
Ramanadham, S.2
-
49
-
-
0027510919
-
Rat and human pancreatic islet cells contain a calcium ion independent phospholipase A2 activity selective for hydrolysis of arachidonate which is stimulated by adenosine triphosphate and is specifically localized to islet beta-cells.
-
Gross RW, Ramanadham S, Kruszka KK. Rat and human pancreatic islet cells contain a calcium ion independent phospholipase A2 activity selective for hydrolysis of arachidonate which is stimulated by adenosine triphosphate and is specifically localized to islet beta-cells. Biochemistry 1993, 32:327-336..
-
(1993)
Biochemistry
, vol.32
-
-
Gross, R.W.1
Ramanadham, S.2
Kruszka, K.K.3
-
50
-
-
0027505285
-
Inhibition of arachidonate release by secretagogue-stimulated pancreatic islets suppresses both insulin secretion and the rise in beta-cell cytosolic calcium ion concentration.
-
Ramanadham S, Gross RW, Han X. Inhibition of arachidonate release by secretagogue-stimulated pancreatic islets suppresses both insulin secretion and the rise in beta-cell cytosolic calcium ion concentration. Biochemistry 1993, 32:337-346..
-
(1993)
Biochemistry
, vol.32
-
-
Ramanadham, S.1
Gross, R.W.2
Han, X.3
-
51
-
-
0033553432
-
Studies of the role of group vi phospholipase A2 in fatty acid incorporation, phospholipid remodeling, lysophosphatidylcholine generation, and secretagogue-induced arachidonic acid release in pancreatic islets and insulinoma cells.
-
Ramanadham S, Hsu F-F, Bohrer A. Studies of the role of group vi phospholipase A2 in fatty acid incorporation, phospholipid remodeling, lysophosphatidylcholine generation, and secretagogue-induced arachidonic acid release in pancreatic islets and insulinoma cells. J Biol Chem 1999, 274:13915-13927..
-
(1999)
J Biol Chem
, vol.274
-
-
Ramanadham, S.1
Hsu, F.-.F.2
Bohrer, A.3
-
52
-
-
0032523059
-
Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism.
-
Zhou Y-P, Teng D, Dralyuk F. Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism. J Clin Invest 1998, 101:1623-1632..
-
(1998)
J Clin Invest
, vol.101
-
-
Zhou, Y.-.P.1
Teng, D.2
Dralyuk, F.3
-
53
-
-
0034674786
-
Distinct roles of two intracellular phospholipase A2s in fatty acid release in the cell death pathway. Proteolytic fragment of type IVA cytosolic phospholipase A2 alpha inhibits stimulus-induced arachidonate release, whereas that of type VI Ca2+-independent phospholipase A2 augments spontaneous fatty acid release.
-
Atsumi G, Murakami M, Kojima K. Distinct roles of two intracellular phospholipase A2s in fatty acid release in the cell death pathway. Proteolytic fragment of type IVA cytosolic phospholipase A2 alpha inhibits stimulus-induced arachidonate release, whereas that of type VI Ca2+-independent phospholipase A2 augments spontaneous fatty acid release. J Biol Chem 2000, 275:18248-18258..
-
(2000)
J Biol Chem
, vol.275
-
-
Atsumi, G.1
Murakami, M.2
Kojima, K.3
-
54
-
-
34548522699
-
The Group VIA calcium-independent phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase.
-
Lei X, Zhang S, Bohrer A. The Group VIA calcium-independent phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase. Biochemistry 2007, 46:10170-10185..
-
(2007)
Biochemistry
, vol.46
-
-
Lei, X.1
Zhang, S.2
Bohrer, A.3
-
55
-
-
58049214863
-
Calcium-independent phospholipase A2 (iPLA2β)-mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosis.
-
Lei X, Zhang S, Bohrer A. Calcium-independent phospholipase A2 (iPLA2β)-mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosis. J Biol Chem 2008, 283:34819-34832..
-
(2008)
J Biol Chem
, vol.283
-
-
Lei, X.1
Zhang, S.2
Bohrer, A.3
-
56
-
-
1642413540
-
The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic β-cells.
-
Nozaki JI, Kubota H, Yoshida H. The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic β-cells. Genes Cells 2004, 9:261-270..
-
(2004)
Genes Cells
, vol.9
-
-
Nozaki, J.I.1
Kubota, H.2
Yoshida, H.3
-
57
-
-
0032524013
-
Mapping of murine diabetogenic gene mody on chromosome 7 at D7Mit258 and its involvement in pancreatic islet and beta cell development during the perinatal period.
-
Kayo T, Koizumi A. Mapping of murine diabetogenic gene mody on chromosome 7 at D7Mit258 and its involvement in pancreatic islet and beta cell development during the perinatal period. J Clin Invest 1988, 101:2112-2118..
-
(1988)
J Clin Invest
, vol.101
-
-
Kayo, T.1
Koizumi, A.2
-
58
-
-
0030907296
-
A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice.
-
Yoshioka M, Kayo T, Ikeda T. A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice. Diabetes 1997, 46:887-894..
-
(1997)
Diabetes
, vol.46
-
-
Yoshioka, M.1
Kayo, T.2
Ikeda, T.3
-
59
-
-
77949899139
-
Spontaneous development of ER stress that can lead to diabetes mellitus is associated with higher calcium-independent phospholipase A2 (iPLA2β) expression: a role for regulation by SREBP-1.
-
Lei X, Zhang S, Barbour SE. Spontaneous development of ER stress that can lead to diabetes mellitus is associated with higher calcium-independent phospholipase A2 (iPLA2β) expression: a role for regulation by SREBP-1. J Biol Chem 2010, 285:6693-6705..
-
(2010)
J Biol Chem
, vol.285
-
-
Lei, X.1
Zhang, S.2
Barbour, S.E.3
-
60
-
-
0029055676
-
Ceramide: a stress signal and mediator of growth suppression and apoptosis.
-
Obeid LM, Hannun YA. Ceramide: a stress signal and mediator of growth suppression and apoptosis. J Cell Biochem 1995, 58:191-198..
-
(1995)
J Cell Biochem
, vol.58
-
-
Obeid, L.M.1
Hannun, Y.A.2
-
61
-
-
0942290632
-
Apoptosis of Insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2β) and suppressed by inhibition of iPLA2β.
-
Ramanadham S, Hsu FF, Zhang S. Apoptosis of Insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2β) and suppressed by inhibition of iPLA2β. Biochemistry 2004, 43:918-930..
-
(2004)
Biochemistry
, vol.43
-
-
Ramanadham, S.1
Hsu, F.F.2
Zhang, S.3
-
62
-
-
0036877142
-
The endoplasmic reticulum: a multifunctional signaling organelle.
-
Berridge MJ. The endoplasmic reticulum: a multifunctional signaling organelle. Cell Calcium 2002, 32:235-249..
-
(2002)
Cell Calcium
, vol.32
-
-
Berridge, M.J.1
-
63
-
-
0034668833
-
Mitochondria and calcium: from cell signalling to cell death.
-
Duchen MR. Mitochondria and calcium: from cell signalling to cell death. J Physiol (Lond) 2000, 529:57-68..
-
(2000)
J Physiol (Lond)
, vol.529
-
-
Duchen, M.R.1
-
64
-
-
0036086440
-
Stimulation of insulin secretion and associated nuclear accumulation of iPLA2β in INS-1 insulinoma cells.
-
Ma Z, Zhang S, Turk J. Stimulation of insulin secretion and associated nuclear accumulation of iPLA2β in INS-1 insulinoma cells. Am J Physiol Endocrinol Metab 2002, 282:E820-E833..
-
(2002)
Am J Physiol Endocrinol Metab
, vol.282
-
-
Ma, Z.1
Zhang, S.2
Turk, J.3
-
65
-
-
77649342685
-
Evidence for proteolytic processing and stimulated organelle redistribution of iPLA2β.
-
Song H, Bao S, Lei X. Evidence for proteolytic processing and stimulated organelle redistribution of iPLA2β. Biochim Biophys Acta Mol Cell Biol Lipids 2010, 298:E1097-E1194..
-
(2010)
Biochim Biophys Acta Mol Cell Biol Lipids
, vol.298
-
-
Song, H.1
Bao, S.2
Lei, X.3
-
66
-
-
0030903804
-
Activation of neutral sphingomyelinase in human neutrophils by polyunsaturated fatty acids.
-
Robinson BS, Hii CS, Poulos A. Activation of neutral sphingomyelinase in human neutrophils by polyunsaturated fatty acids. Immunology 1997, 91:274-280..
-
(1997)
Immunology
, vol.91
-
-
Robinson, B.S.1
Hii, C.S.2
Poulos, A.3
-
67
-
-
26244456414
-
ER stress and SREBP-1 activation are implicated in β-cell glucolipotoxicity.
-
Wang H, Kouri G, Wollheim CB. ER stress and SREBP-1 activation are implicated in β-cell glucolipotoxicity. J Cell Sci 2005, 118:3905-3915..
-
(2005)
J Cell Sci
, vol.118
-
-
Wang, H.1
Kouri, G.2
Wollheim, C.B.3
-
68
-
-
0030007427
-
ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism.
-
Kim JB, Spiegelman B. ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism. Genes Dev 1996, 10:1096-1107..
-
(1996)
Genes Dev
, vol.10
-
-
Kim, J.B.1
Spiegelman, B.2
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