Type 2 diabetes mellitus and β cell apoptosis;Diabete de type 2 et apoptose des cellules β

Diabetes and Metabolism

Volumn 26, Issue SUPPL. 3, 2000, Pages 13-16

  Cerasi, E ^a   Kaiser, N ^b   Leibowitz, G ^b  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b NONE

Author keywords

Apoptosis pancreatic cells; Diabetes; Psammomys obesus

Indexed keywords

NITRIC OXIDE; INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CALORIC INTAKE; CONTROLLED STUDY; DIABETIC KETOACIDOSIS; IN VITRO STUDY; INSULIN DEFICIENCY; LIFESTYLE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PATHOPHYSIOLOGY; RAT; ANIMAL; DISEASE MODEL; GENETICS; GERBIL; HUMAN; PANCREAS ISLET; PATHOLOGY; PROMOTER REGION; REVIEW;

ANIMALS; APOPTOSIS; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; GERBILLINAE; HUMANS; INSULIN; ISLETS OF LANGERHANS; PROMOTER REGIONS (GENETICS);

EID: 0034203929     PISSN: 12623636     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. UK Prospective Diabetes Study Group. Overview of 6 years therapy of type 2 diabetes, a progressive disease. Diabetes, 1995, 44, 1249-1258.
2. Loubatières A. Physiologie et pharmacodynamie de certains dérivés sulfamidés hypoglycémiants. Contribution à l'étude des substances synthétiques à tropisme endocrinien. Thèse Doct. ès Sci. Naturelles. Causse. Graille et Castelnau, Imprimeurs, Montpellier, 1946.
3. Grodsky GM, Landahl H, Curry D, Bennett LL. In vitro studies suggesting a two compartmental model for insulin secretion. In Falkmer S, Hellman B, Taljedal IB: Structure and metabolism of the pancretaic islets. Pergamon Press. Oxford, 1470, 409-420.
4. Cerasi E. Insulin deficiency and insulin resistance in the pathogenesis of NIDDM: is a divorce possible? Diabetologia, 1995, 38, 992-997.
5. Shafrir E, Gutman A. Psammomys obesus of the Jerusalem colony: A model for nutritionnaly induced non-insulin-dependent diabetes. J Basic Clin Physiol Pharmacol, 1993, 4, 83-99.
6. Kalderon B, Gutman A, Levy E, et al. Characterization of stages in development of obesity-diabetes syndrome in the sand rat (Psammomys obesus). Diabetes, 1996, 35, 717-723.
7. Nesher R, Gross DJ, Donath MY, Cerasi E, Kaiser N. Interaction between genetic and dietary factors determines beta-cell function in Psammomys obesus, an animal model of type 2 diabetes. Diabetes, 1999, 48, 731-737.
8. Kaiser N, Donath MY, Gross DJ, Cerasi E. Diabète non insulinodépendant et apoptose des cellules β. In Journées de Diabétologie de l'Hôtel Dieu. Flammarion Médecine Sciences, 1999, 13-23.
9. German M, Stephen A, Docherty K, Edlund H, Edlund T, Goodison S. et al. The insulin gene promoter. Diabetes, 1995, 44, 1002-1004.
10. Marshak S, Totary H, Cerasi E, Melloul D. Purification of the beta cell glucose sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells. Proc Natl Acad Sci, 1996, 93, 15057-15062.
11. Marshak S, Leibowitz G, Bertuzzi F, Socci C, Kaiser N, Gross DJ, Cerasi E, Melloul D. Impaired beta-cell functions induced by chronic exposure of cultured human pancreatic islets to high glucose. Diabetes, 1999, 48, 1230-1236.
12. Donath MY, Gross DJ, Cerasi E, Kaiser N. Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes. Diabetes, 1999, 48, 738-744.
13. Gavrielli Y, Sherman Y, Ben Sasson SA. Identification of programmed cell death in vivo via specific labeling of nuclear DNA fragmentation. J Cell Biol. 1992, 199, 493-501.
14. Corbett JA, Tilton RG, Chang K, Hasan KS, Ido Y, Wang JL, Sweetland MA, Lancaster JRJ, Williamson JR, McDaniel ML. Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction. Diabetes, 1992, 41, 552-556.