Mass spectrometric evidence that agents that cause loss of Ca2+ from intracellular compartments induce hydrolysis of arachidonic acid from pancreatic islet membrane phospholipids by a mechanism that does not require a rise in cytosolic Ca2+ concentration

Endocrinology

Volumn 139, Issue 10, 1998, Pages 4073-4085

  Nowatzke, William ^a   Ramanadham, Sasanka ^a   Ma, Zhongmin ^a   Hsu, Fong Fu ^a   Bohrer, Alan ^a   Turk, John ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIMYCIN; CALCIUM; CALCIUM CHANNEL; PHOSPHOLIPID; THAPSIGARGIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARACHIDONIC ACID METABOLISM; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CATALYSIS; EXOCYTOSIS; HYDROLYSIS; INSULIN RELEASE; ION CURRENT; MALE; MASS SPECTROMETRY; MEMBRANE DEPOLARIZATION; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT;

EID: 0031733287     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.10.6225     Document Type: Article

References (69)

1. Porte D 1991 Beta cells in diabetes mellitus. Diabetes 40:166-180
2. Meglasson MD, Matschinsky FM 1986 Pancreatic islet glucose metabolism and regulation of insulin secretion. Diabetes Metab Rev 2:163-214
3. + channels in pancreatic β-cells. Nature 311:271-273
4. 2+ concentration in pancreatic β-cells. J Biol Chem 262:5448-5454
5. Gylfe E 1988 Glucose-induced early changes in cytoplasmic calcium of pancreatic β-cells studied with time-sharing dual-wavelength fluorometry. J Biol Chem 263:5044-5048
6. Misler S, Barnett D, Gillis K, Pressel D 1992 Electrophysiology of stimulus-secretion coupling in human β-cells. Diabetes 41:1221-1228
7. 2+ entry. Diabetes 41:662-670
8. 2+ mobilization by arachidonic acid. Comparison with myo-inositol 1,4,5-trisphosphate in isolated pancreatic islets. J Biol Chem 261:3501-3511
9. Wolf BA, Pasquale SM, Turk J 1991 Free fatty acid accumulation in secretagogue-stimulated pancreatic islets and effects of arachidonate on depolarization-induced insulin secretion. Biochemistry 30:6371-6379
10. Ramanadham S, Gross RW, Turk J 1992 Arachidonic acid elevates cytosolic free calcium concentration in individual pancreatic islet β-cells. Biochem Biophys Res Commun 184:647-653
11. 2+ activity of mouse pancreatic beta cells. FEBS Lett 170:196-200
12. 2+ in mouse islets of Langerhans. Am J Physiol 266:E852-E862
13. 2+ in mouse pancreatic beta cells. J Physiol 485:607-617
14. 2+ stores. Endocrinology 105:1013-1019
15. Roe MW, Lancaster ME, Mertz J, Worley JF, Dukes ID 1993 Voltage-dependent intracellular calcium release from mouse islets stimulated by glucose. J Biol Chem 268:9953-9956
16. 2+ release in mouse islets by a phospholipase C-dependent mechanism. Biophys J 68:A235 (Abstract)
17. 2+ stores activates a maitotoxin-sensitive non-selective cationic current in β-cells. J Biol Chem 269:32055-32058
18. Worley JF, McIntyre MS, Spencer B, Mertz RJ, Roe MW, Dukes ID 1994 Endoplasmic reticulum calcium store regulates membrane potential in mouse islet β-cells. J Biol Chem 269:14359-14362
19. 2+ stores and plasma membrane ion channels. Curr Opin Endocrinol Diab 4:262-271
20. 3 pituitary cells. Am J Physiol 257:E203-E211
21. Miller B, Sarantis M, Traynelis SF, Atwell D 1993 Potentiation of NMDA receptor currents by arachidonic acid. Nature 355:722-725
22. Petrou S, Ordway R, Singer J, Walsh J 1993 A putative fatty acid-binding domain of the NMDA receptor. Trends Biochem Sci 18:41-42
23. Meeves H 1994 Modulation of ion channels by arachidonic acid. Prog Neurobiol 43:175-186
24. 2 action in the insulin-secreting HIT cell line. Am J Physiol 268:C181-C190
25. Ramanadham S, Gross RW, Han X, Turk J 1993 Inhibition of arachidonate release by secretagogue-stimulated pancreatic islets suppresses both insulin secretion and the rise in β-cell cytosolic calcium ion concentration. Biochemistry 32:337-346
26. 2+ stores and arachidonic acid metabolism. J Clin Invest 101:1623-1632
27. Needleman P, Turk J, Jakschik BA, Morrison AR, Lefkowith JB 1986 Arachidonic acid metabolism. Annu Rev Biochem 55:35-68
28. Ma Z, Ramanadham S, Corbett JA, Bohrer A, Gross RW, McDaniel ML, Turk J 1996 Interleukin-1 enhances pancreatic islet arachidonic acid 12-lipoxygenase product generation by increasing substrate availability through a nitric oxide-dependent mechanism. J Biol Chem 271:1029-1042
29. McDaniel ML, Colca JR, Kotagal N, Lacy PE1983 A subcellular fractionation approach for studying insulin release mechanisms and calcium metabolism in islets of Langerhans. Methods Enzymol 98:182-200
30. Turk J, Colca JR, Kotagal N, McDaniel ML 1984 Arachidonic acid metabolism in isolated pancreatic islets II. The influence of glucose and of inhibitors of arachidonate metabolism on insulin secretion and metabolite synthesis. Biochim Biophys Acta 794:125-136
31. Hsu FF, Bohrer A, Turk J 1998 Formation of lithiated adducts of glycero-phosphocholine lipids facilitates their identification by electrospray ionization tandem mass spectrometry. J Am Soc Mass Spectrom 9:516-526
32. Ramanadham S, Hsu FF, Bohrer A, Nowatzke W, Ma Z, Turk J 1998 Electrospray ionization mass spectrometric analyses of phospholipids from rat and human pancreatic islets and subcellular membranes. Comparison to other tissues and implications for membrane fusion in insulin exocytosis. Biochemistry 37:4553-4567
33. Ramanadham S, Bohrer A, Mueller M, Jett P, Gross RW, Turk J 1993 Mass spectrometric identification and quantitation of arachidonate-containing phospholipids in pancreatic islets: prominence of plasmenylethanolamine molecular species. Biochemistry 32:5339-5351
34. Ono J, Takaki R, Fukama M 1977 Preparation of single cells from pancreatic islets of adult rats by the use of dispase. Endocrinol Jpn 24:265-270
35. Van De Winkel M, Maes E, Pipeleers DB 1982 Islet cell analysis and purification by light scatter and autofluorescence. Biochem Biophys Res Commun 107:525-532
36. 2+ in single β- and α-cells obtained from pancreatic islets by fluorescence-activated cell-sorting. Biochem Biophys Res Commun 166:813-818
37. 2+ in individual small cells using fluorescence microscopy with dual excitation wavelengths. Cell Calcium 6:145-157
38. 2 enzyme that contains a repeated structural motif homologous to the integral membrane protein binding domain of ankyrin. J Biol Chem 272:11118-11127
39. 2 produced in baculovirus-infected insect cells. Biotechnology 12:69-74
40. 2 expressed in insect cells and present in human monocytes. J Biol Chem 271:6987-6997
41. O'Reiliy DR, Miller LK, Luckow VA 1992 Baculovirus Expression Vectors: A Laboratory Manual. WH Freeman & Co, New York
42. 2 activity selective for hydrolysis of arachidonate which is stimulated by ATP and specifically localized to islet beta cells. Biochemistry 32:327-336
43. Rzigalinski BA, Blackmore PF, Rosenthal MD 1996 Arachidonate mobilization is coupled to depletion of intracellular calcium stores and influx of extracellular calcium in differentiated U937 cells. Biochim Biophys Acta 1299:342-352
44. 2. A novel mechanism underlying arachidonic acid release. J Biol Chem 272:1522-1527
45. 2 isoforms in human and rat pancreatic islets and insulin-secreting β-cell lines. Endocrinology 137:2901-2909
46. 2 in pancreatic beta cells. Regulation of mRNA levels by starvation or glucose excess. FEBS Lett 295:110-112
47. 2. Biochim Biophys Acta 1391:384-400
48. 2. J Biol Chem 266:7227-7232
49. 2. J Med Chem 36:95-100
50. 2. J Biol Chem 272:16069-16072
51. 2 enzymes present in P388D1 macrophages. J Biol Chem 271:6758-6765
52. Balsinde J, Dennis EA 1996 Bromoenol lactone inhibits magnesium-dependent phosphatidate phosphohydrolase and blocks triacylglycerol biosynthesis in mouse P388D1 macrophages. J Biol Chem 271:31937-31941
53. Dunlop ME, Larkins G 1985 Presence of membrane-associated phosphatidate phosphohydrolase activity in cultured islets and its stimulation by glucose. FEBS Lett 193:231-235
54. Metz SA, Dunlop ME 1991 Inhibition of the metabolism of phosphatidylethanol and phosphatidic acid and stimulation of insulin release by propranolol in intact pancreatic islets. Biochem Pharmacol 41:R1-R4
55. Tsien RY 1981 A non-disruptive technique for loading calcium buffers and indicators into cells. Nature 290:527-528
56. Billman GE 1993 Intracellular calcium chelator, BAPTA-AM, prevents cocaine-induced ventricular fibrillation. Am J Physiol 265:H1529-H1535
57. 2+-ATPase. Proc Natl Acad Sci USA 87:2466-2470
58. 2+ transport ATPases. Arch Biochem Biophys 298:313-317
59. 2. J Biol Chem 271:20989-20992
60. 2. J Biol Chem 271:30879-30885
61. 2 enzyme in clonal insulinoma cell lines. Biochim Biophys Acta L1344:153-164
62. 2 from clonal insulin-secreting HIT cells and rat pancreatic islets. A possible molecular component of the beta cell fuel sensor. Biochemistry 33:7442-7452
63. 2 from pancreatic islets and HIT insulinoma cells with a phosphofructokinase-like protein. Biochemistry 35:5464-5471
64. Turk J, Mueller M, Bohrer A, Ramanadham S 1992 Arachidonic acid metabolism in isolated pancreatic islets VI. Carbohydrate insulin secretagogues must be metabolized to induce eicosanoid release. Biochim Biophys Acta 1125:280-291
65. Konrad R, Jolly Y, Major C, Wolf BA 1993 Fuel secretagogue stimulation of arachidonic acid accumulation in islets. Mol Cell Endocrinol 92:135-140
66. Putney JW 1986 A model of receptor-regulated calcium entry. Cell Calcium 7:1-12
67. 2+ influx in human neutrophils is secondary to the emptying of intracellular calcium stores. Biochem J 277:73-79
68. Gericke M, Droogmans G, Nilius B 1993 Thapsigargin discharges intracellular calcium stores and induces transmembrane currents in human endothelial cells. Pflugers Arch 422:552-557
69. Clapham DE 1995 Replenishing the stores. Nature 375:634-635