The role of the placenta in fetal exposure to xenobiotics: Importance of membrane transporters and human models for transfer studies

Drug Metabolism and Disposition

Volumn 38, Issue 10, 2010, Pages 1623-1635

  Prouillac, Caroline ^a   Lecoeur, Sylvaine ^a  

^a VETAGRO SUP   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ABCB3; AVERMECTIN; BREAST CANCER RESISTANCE PROTEIN; CYTOCHROME P450; DIGOXIN; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; FOLATE TRANSPORTER; GLYCOPROTEIN P; INDINAVIR; MEMBRANE PROTEIN; MONOCARBOXYLATE TRANSPORTER; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; ORGANIC ANION TRANSPORTER; ORGANIC CATION TRANSPORTER; PACLITAXEL; PLACENTA ENZYME; SAQUINAVIR; UNCLASSIFIED DRUG; VESICULAR MONOAMINE TRANSPORTER; XENOBIOTIC AGENT;

BIOTRANSFORMATION; BLOOD PLACENTA BARRIER; BLOOD SAMPLING; CANCER CELL CULTURE; CHORIOCARCINOMA; COTYLEDON; CYTOTROPHOBLAST; DRUG DELIVERY SYSTEM; DRUG METABOLISM; FETOMATERNAL TRANSFUSION; FETUS DEVELOPMENT; FETUS GROWTH; HUMAN; MEMBRANE TRANSPORT; MEMBRANE VESICLE; NONHUMAN; PHYSIOLOGY; PLACENTAL TRANSFER; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHORT SURVEY; SOLUTE; TOXICOLOGY; TROPHOBLAST; WESTERN BLOTTING; XENOBIOTIC METABOLISM;

BIOLOGICAL TRANSPORT; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; HUMANS; MATERNAL-FETAL EXCHANGE; MEMBRANE TRANSPORT PROTEINS; MODELS, BIOLOGICAL; PLACENTA; PREGNANCY; XENOBIOTICS;

EID: 77957122945     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.110.033571     Document Type: Short Survey

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