-
1
-
-
42249105540
-
Pituitary tumors in childhood: Update of diagnosis, treatment and molecular genetics
-
Keil MF, Stratakis CA. Pituitary tumors in childhood: update of diagnosis, treatment and molecular genetics. Expert Rev. Neurother. 8(4), 563-574 (2008).
-
(2008)
Expert Rev. Neurother.
, vol.8
, Issue.4
, pp. 563-574
-
-
Keil, M.F.1
Stratakis, C.A.2
-
2
-
-
33845489470
-
High prevalence of pituitary adenomas: A cross-sectional study in the province of Liege, Belgium
-
Daly AF, Rixhon M, Adam C, Dempegioti A, Tichomirowa MA, Beckers A. High prevalence of pituitary adenomas: a cross-sectional study in the province of Liege, Belgium. J. Clin. Endocrinol. Metab. 91(12), 4769-4775 (2006).
-
(2006)
J. Clin. Endocrinol. Metab.
, vol.91
, Issue.12
, pp. 4769-4775
-
-
Daly, A.F.1
Rixhon, M.2
Adam, C.3
Dempegioti, A.4
Tichomirowa, M.A.5
Beckers, A.6
-
3
-
-
3242786475
-
The prevalence of pituitary adenomas: A systematic review
-
Ezzat S, Asa SL, Couldwell WT et al. The prevalence of pituitary adenomas: a systematic review. Cancer 101(3), 613-619 (2004).
-
(2004)
Cancer
, vol.101
, Issue.3
, pp. 613-619
-
-
Ezzat, S.1
Asa, S.L.2
Couldwell, W.T.3
-
4
-
-
76649132060
-
Prevalence of pituitary adenomas: A community-based, cross-sectional study in Banbury (Oxfordshire, UK)
-
Fernandez A, Karavitaki N, Wass JA. Prevalence of pituitary adenomas: a community-based, cross-sectional study in Banbury (Oxfordshire, UK). Clin. Endocrinol. (Oxf.) 72(3), 377-382 (2010).
-
(2010)
Clin. Endocrinol. (Oxf.)
, vol.72
, Issue.3
, pp. 377-382
-
-
Fernandez, A.1
Karavitaki, N.2
Wass, J.A.3
-
6
-
-
58049101614
-
Update on the treatment of pituitary adenomas: Familial and genetic considerations
-
Daly AF, Beckers A. Update on the treatment of pituitary adenomas: familial and genetic considerations. Acta Clin. Belg. 63(6), 418-424 (2008).
-
(2008)
Acta Clin. Belg.
, vol.63
, Issue.6
, pp. 418-424
-
-
Daly, A.F.1
Beckers, A.2
-
7
-
-
18344391292
-
Hereditary hormone excess: Genes, molecular pathways, and syndromes
-
Marx SJ, Simonds WF. Hereditary hormone excess: genes, molecular pathways, and syndromes. Endocr. Rev. 26(5), 615-661 (2005).
-
(2005)
Endocr. Rev.
, vol.26
, Issue.5
, pp. 615-661
-
-
Marx, S.J.1
Simonds, W.F.2
-
8
-
-
0023625538
-
Pituitary adenomas of the multiple endocrine neoplasia type i syndrome
-
Scheithauer BW, Laws ER Jr, Kovacs K, Horvath E, Randall RV, Carney JA. Pituitary adenomas of the multiple endocrine neoplasia type I syndrome. Semin. Diagn. Pathol. 4(3), 205-211 (1987).
-
(1987)
Semin. Diagn. Pathol.
, vol.4
, Issue.3
, pp. 205-211
-
-
Scheithauer, B.W.1
Laws Jr., E.R.2
Kovacs, K.3
Horvath, E.4
Randall, R.V.5
Carney, J.A.6
-
10
-
-
0031797339
-
The MEN-1 gene is rarely down-regulated in pituitary adenomas
-
Asa SL, Somers K, Ezzat S. The MEN-1 gene is rarely down-regulated in pituitary adenomas. J. Clin. Endocrinol. Metab. 83(9), 3210-3212 (1998).
-
(1998)
J. Clin. Endocrinol. Metab.
, vol.83
, Issue.9
, pp. 3210-3212
-
-
Asa, S.L.1
Somers, K.2
Ezzat, S.3
-
11
-
-
18644370689
-
Sequence analysis of the PRKAR1A gene in sporadic somatotroph and other pituitary tumours
-
Kaltsas GA, Kola B, Borboli N et al. Sequence analysis of the PRKAR1A gene in sporadic somatotroph and other pituitary tumours. Clin. Endocrinol. (Oxf.) 57(4), 443-448 (2002).
-
(2002)
Clin. Endocrinol. (Oxf.)
, vol.57
, Issue.4
, pp. 443-448
-
-
Kaltsas, G.A.1
Kola, B.2
Borboli, N.3
-
12
-
-
10844227998
-
Proliferation of transformed somatotroph cells related to low or absent expression of protein kinase a regulatory subunit 1A protein
-
Lania AG, Mantovani G, Ferrero S et al. Proliferation of transformed somatotroph cells related to low or absent expression of protein kinase a regulatory subunit 1A protein. Cancer Res. 64(24), 9193-9198 (2004).
-
(2004)
Cancer Res.
, vol.64
, Issue.24
, pp. 9193-9198
-
-
Lania, A.G.1
Mantovani, G.2
Ferrero, S.3
-
13
-
-
0033051303
-
Somatic MEN1 gene mutation does not contribute significantly to sporadic pituitary tumorigenesis
-
Poncin J, Stevenaert A, Beckers A. Somatic MEN1 gene mutation does not contribute significantly to sporadic pituitary tumorigenesis. Eur. J. Endocrinol. 140(6), 573-576 (1999).
-
(1999)
Eur. J. Endocrinol.
, vol.140
, Issue.6
, pp. 573-576
-
-
Poncin, J.1
Stevenaert, A.2
Beckers, A.3
-
14
-
-
33750361636
-
Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans
-
Pellegata NS, Quintanilla-Martinez L, Siggelkow H et al. Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans. Proc. NatlAcad. Sci. USA 103(42), 15558-15563 (2006).
-
(2006)
Proc. NatlAcad. Sci. USA
, vol.103
, Issue.42
, pp. 15558-15563
-
-
Pellegata, N.S.1
Quintanilla-Martinez, L.2
Siggelkow, H.3
-
15
-
-
33744486595
-
Pituitary adenoma predisposition caused by germline mutations in the AIP gene
-
Vierimaa O, Georgitsi M, Lehtonen R et al. Pituitary adenoma predisposition caused by germline mutations in the AIP gene. Science 312(5777), 1228-1230 (2006).
-
(2006)
Science
, vol.312
, Issue.5777
, pp. 1228-1230
-
-
Vierimaa, O.1
Georgitsi, M.2
Lehtonen, R.3
-
16
-
-
34249844835
-
Aryl hydrocarbon receptor-interacting protein gene mutations in familial isolated pituitary adenomas: Analysis in 73 families
-
Daly AF, Vanbellinghen JF, Khoo SK et al. Aryl hydrocarbon receptor-interacting protein gene mutations in familial isolated pituitary adenomas: analysis in 73 families. J. Clin. Endocrinol. Metab. 92(5), 1891-1896 (2007).
-
(2007)
J. Clin. Endocrinol. Metab.
, vol.92
, Issue.5
, pp. 1891-1896
-
-
Daly, A.F.1
Vanbellinghen, J.F.2
Khoo, S.K.3
-
17
-
-
34547426945
-
Germline inactivating mutations of the aryl hydrocarbon receptor-interacting protein gene in a large cohort of sporadic acromegaly: Mutations are found in a subset of young patients with macroadenomas
-
Cazabat L, Libe R, Perlemoine K et al. Germline inactivating mutations of the aryl hydrocarbon receptor-interacting protein gene in a large cohort of sporadic acromegaly: mutations are found in a subset of young patients with macroadenomas. Eur. J. Endocrinol. 157(1), 1-8 (2007).
-
(2007)
Eur. J. Endocrinol.
, vol.157
, Issue.1
, pp. 1-8
-
-
Cazabat, L.1
Libe, R.2
Perlemoine, K.3
-
18
-
-
34247180053
-
Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations
-
Georgitsi M, Raitila A, Karhu A et al. Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations. Proc. Natl Acad. Sci. USA 104(10), 4101-4105 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, Issue.10
, pp. 4101-4105
-
-
Georgitsi, M.1
Raitila, A.2
Karhu, A.3
-
19
-
-
34447560185
-
Germline CDKN1B/p27Kip1 mutation in multiple endocrine neoplasia
-
Georgitsi M, Raitila A, Karhu A et al. Germline CDKN1B/p27Kip1 mutation in multiple endocrine neoplasia. J. Clin. Endocrinol. Metab. 92(8), 3321-3325 (2007).
-
(2007)
J. Clin. Endocrinol. Metab.
, vol.92
, Issue.8
, pp. 3321-3325
-
-
Georgitsi, M.1
Raitila, A.2
Karhu, A.3
-
20
-
-
66149129256
-
Rare germline mutations in cyclin-dependent kinase inhibitor genes in multiple endocrine neoplasia type 1 and related states
-
Agarwal SK, Mateo CM, Marx SJ. Rare germline mutations in cyclin-dependent kinase inhibitor genes in multiple endocrine neoplasia type 1 and related states. J. Clin. Endocrinol. Metab. 94(5), 1826-1834 (2009).
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, Issue.5
, pp. 1826-1834
-
-
Agarwal, S.K.1
Mateo, C.M.2
Marx, S.J.3
-
21
-
-
18244392974
-
Pituitary disease in MEN type 1 (MEN1): Data from the France-Belgium MEN1 multicenter study
-
Verges B, Boureille F, Goudet P et al. Pituitary disease in MEN type 1 (MEN1): data from the France-Belgium MEN1 multicenter study. J. Clin. Endocrinol. Metab. 87(2), 457-465 (2002).
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, Issue.2
, pp. 457-465
-
-
Verges, B.1
Boureille, F.2
Goudet, P.3
-
22
-
-
0842330809
-
Cushings disease as the first clinical manifestation of multiple endocrine neoplasia type 1 (MEN1) associated with an R460X mutation of the MEN1 gene
-
Matsuzaki LN, Canto-Costa MH, Hauache OM. Cushings disease as the first clinical manifestation of multiple endocrine neoplasia type 1 (MEN1) associated with an R460X mutation of the MEN1 gene. Clin. Endocrinol. (Oxf.) 60(1), 142-143 (2004).
-
(2004)
Clin. Endocrinol. (Oxf.)
, vol.60
, Issue.1
, pp. 142-143
-
-
Matsuzaki, L.N.1
Canto-Costa, M.H.2
Hauache, O.M.3
-
23
-
-
11844306569
-
Cushings disease in childhood as the first manifestation of multiple endocrine neoplasia syndrome type 1
-
Rix M, Hertel NT, Nielsen FC et al. Cushings disease in childhood as the first manifestation of multiple endocrine neoplasia syndrome type 1. Eur. J. Endocrinol. 151(6), 709-715 (2004).
-
(2004)
Eur. J. Endocrinol.
, vol.151
, Issue.6
, pp. 709-715
-
-
Rix, M.1
Hertel, N.T.2
Nielsen, F.C.3
-
24
-
-
33751104763
-
Role of Brg1 and HDAC2 in GR trans-repression of the pituitary POMC gene and misexpression in Cushing disease
-
Bilodeau S, Vallette-Kasic S, Gauthier Y et al. Role of Brg1 and HDAC2 in GR trans-repression of the pituitary POMC gene and misexpression in Cushing disease. Genes Dev. 20(20), 2871-2886 (2006).
-
(2006)
Genes Dev.
, vol.20
, Issue.20
, pp. 2871-2886
-
-
Bilodeau, S.1
Vallette-Kasic, S.2
Gauthier, Y.3
-
25
-
-
9044238065
-
Nelsons syndrome associated with a somatic frame shift mutation in the glucocorticoid receptor gene
-
Karl M, Von Wichert G, Kempter E et al. Nelsons syndrome associated with a somatic frame shift mutation in the glucocorticoid receptor gene. J. Clin. Endocrinol. Metab. 81(1), 124-129 (1996).
-
(1996)
J. Clin. Endocrinol. Metab.
, vol.81
, Issue.1
, pp. 124-129
-
-
Karl, M.1
Von Wichert, G.2
Kempter, E.3
-
26
-
-
61449143634
-
P53 gene mutation in an atypical corticotroph adenoma with Cushings disease
-
Kawashima ST, Usui T, Sano T et al. P53 gene mutation in an atypical corticotroph adenoma with Cushings disease. Clin. Endocrinol. (Oxf.) 70(4), 656-657 (2009).
-
(2009)
Clin. Endocrinol. (Oxf.)
, vol.70
, Issue.4
, pp. 656-657
-
-
Kawashima, S.T.1
Usui, T.2
Sano, T.3
-
27
-
-
4043111906
-
Multiple endocrine neoplasia type 1 variant with frequent prolactinoma and rare gastrinoma
-
Hao W, Skarulis MC, Simonds WF et al. Multiple endocrine neoplasia type 1 variant with frequent prolactinoma and rare gastrinoma. J. Clin. Endocrinol. Metab. 89(8), 3776-3784 (2004).
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, Issue.8
, pp. 3776-3784
-
-
Hao, W.1
Skarulis, M.C.2
Simonds, W.F.3
-
28
-
-
8044258981
-
A kindred with a variant of multiple endocrine neoplasia type 1 demonstrating frequent expression of pituitary tumors but not linked to the multiple endocrine neoplasia type 1 locus at chromosome region 11q13
-
Stock JL, Warth MR, Teh BT et al. A kindred with a variant of multiple endocrine neoplasia type 1 demonstrating frequent expression of pituitary tumors but not linked to the multiple endocrine neoplasia type 1 locus at chromosome region 11q13. J. Clin. Endocrinol. Metab. 82(2), 486-492 (1997).
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, Issue.2
, pp. 486-492
-
-
Stock, J.L.1
Warth, M.R.2
Teh, B.T.3
-
29
-
-
70449366466
-
Acromegaly pathogenesis and treatment
-
Melmed S. Acromegaly pathogenesis and treatment. J. Clin. Invest. 119(11), 3189-3202 (2009).
-
(2009)
J. Clin. Invest.
, vol.119
, Issue.11
, pp. 3189-3202
-
-
Melmed, S.1
-
30
-
-
71049194270
-
Signalling pathway alterations in pituitary adenomas: Involvement of Gsa, cAMP and mitogen-activated protein kinases
-
Pertuit M, Barlier A, Enjalbert A, Gerard C. Signalling pathway alterations in pituitary adenomas: involvement of Gsa, cAMP and mitogen-activated protein kinases. J. Neuroendocrinol. 21(11), 869-877 (2009).
-
(2009)
J. Neuroendocrinol.
, vol.21
, Issue.11
, pp. 869-877
-
-
Pertuit, M.1
Barlier, A.2
Enjalbert, A.3
Gerard, C.4
-
31
-
-
38149123363
-
Regulating gene transcription in response to cyclic AMP elevation
-
Sands WA, Palmer TM. Regulating gene transcription in response to cyclic AMP elevation. Cell Signal. 20(3), 460-466 (2008).
-
(2008)
Cell Signal.
, vol.20
, Issue.3
, pp. 460-466
-
-
Sands, W.A.1
Palmer, T.M.2
-
32
-
-
31144433061
-
Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents
-
Lugnier C. Cyclic nucleotide phosphodiesterase (PDE) superfamily: a new target for the development of specific therapeutic agents. Pharmacol. Ther. 109(3), 366-398 (2006).
-
(2006)
Pharmacol. Ther.
, vol.109
, Issue.3
, pp. 366-398
-
-
Lugnier, C.1
-
33
-
-
0036771614
-
The Gsa gene: Predominant maternal origin of transcription in human thyroid gland and gonads
-
Mantovani G, Ballare E, Giammona E, Beck-Peccoz P, Spada A. The Gsa gene: predominant maternal origin of transcription in human thyroid gland and gonads. J. Clin. Endocrinol. Metab. 87(10), 4736-4740 (2002).
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, Issue.10
, pp. 4736-4740
-
-
Mantovani, G.1
Ballare, E.2
Giammona, E.3
Beck-Peccoz, P.4
Spada, A.5
-
35
-
-
33745232387
-
McCune-Albright syndrome: Clinical picture and natural history in children and adolescents
-
Volkl TM, Dorr HG. McCune-Albright syndrome: clinical picture and natural history in children and adolescents. J. Pediatr. Endocrinol. Metab. 19(Suppl. 2), 551-559 (2006).
-
(2006)
J. Pediatr. Endocrinol. Metab.
, vol.19
, Issue.SUPPL. 2
, pp. 551-559
-
-
Volkl, T.M.1
Dorr, H.G.2
-
36
-
-
0024389295
-
Saeed uz-Zafar M, Levitsky LL, Mellinger RC, Frohman LA. Hypersecretion of growth hormone and prolactin in McCune-Albright syndrome
-
Cuttler L, Jackson JA, Saeed uz-Zafar M, Levitsky LL, Mellinger RC, Frohman LA. Hypersecretion of growth hormone and prolactin in McCune-Albright syndrome. J. Clin. Endocrinol. Metab. 68(6), 1148-1154 (1989).
-
(1989)
J. Clin. Endocrinol. Metab.
, vol.68
, Issue.6
, pp. 1148-1154
-
-
Cuttler, L.1
Jackson, J.A.2
-
37
-
-
0021272053
-
Mammosomatotroph hyperplasia associated with acromegaly and hyperprolactinemia in a patient with the McCune-Albright syndrome. A histologic, immunocytologic and ultrastructural study of the surgically-removed adenohypophysis
-
Kovacs K, Horvath E, Thorner MO, Rogol AD. Mammosomatotroph hyperplasia associated with acromegaly and hyperprolactinemia in a patient with the McCune-Albright syndrome. A histologic, immunocytologic and ultrastructural study of the surgically-removed adenohypophysis. Virchows Arch. A Pathol. Anat. Histopathol. 403(1), 77-86 (1984).
-
(1984)
Virchows Arch. A Pathol. Anat. Histopathol.
, vol.403
, Issue.1
, pp. 77-86
-
-
Kovacs, K.1
Horvath, E.2
Thorner, M.O.3
Rogol, A.D.4
-
38
-
-
0035938911
-
Clinical picture: Fuel on the fire
-
Uwaifo GI, Robey PG, Akintoye SO, Collins MT. Clinical picture: fuel on the fire. Lancet 357(9273), 2011 (2001).
-
(2001)
Lancet
, vol.357
, Issue.9273
, pp. 2011
-
-
Uwaifo, G.I.1
Robey, P.G.2
Akintoye, S.O.3
Collins, M.T.4
-
39
-
-
33845473676
-
McCune-Albright syndrome and acromegaly: Effects of hypothalamopituitary radiotherapy and/or pegvisomant in somatostatin analog-resistant patients
-
Galland F, Kamenicky P, Affres H et al. McCune-Albright syndrome and acromegaly: effects of hypothalamopituitary radiotherapy and/or pegvisomant in somatostatin analog-resistant patients. J. Clin. Endocrinol. Metab. 91(12), 4957-4961 (2006).
-
(2006)
J. Clin. Endocrinol. Metab.
, vol.91
, Issue.12
, pp. 4957-4961
-
-
Galland, F.1
Kamenicky, P.2
Affres, H.3
-
41
-
-
0025285138
-
A new constitutively activating mutation of the Gs protein a subunit-Gsp oncogene is found in human pituitary tumours
-
Clementi E, Malgaretti N, Meldolesi J, Taramelli R. A new constitutively activating mutation of the Gs protein a subunit-Gsp oncogene is found in human pituitary tumours. Oncogene 5(7), 1059-1061 (1990).
-
(1990)
Oncogene
, vol.5
, Issue.7
, pp. 1059-1061
-
-
Clementi, E.1
Malgaretti, N.2
Meldolesi, J.3
Taramelli, R.4
-
42
-
-
0024404145
-
GTPase inhibiting mutations activate the a chain of Gs and stimulate adenylyl cyclase in human pituitary tumours
-
Landis CA, Masters SB, Spada A, Pace AM, Bourne HR, Vallar L. GTPase inhibiting mutations activate the a chain of Gs and stimulate adenylyl cyclase in human pituitary tumours. Nature 340(6236), 692-696 (1989).
-
(1989)
Nature
, vol.340
, Issue.6236
, pp. 692-696
-
-
Landis, C.A.1
Masters, S.B.2
Spada, A.3
Pace, A.M.4
Bourne, H.R.5
Vallar, L.6
-
43
-
-
0029017174
-
The cyclic adenosine 3,5-monophosphate-responsive factor CREB is constitutively activated in human somatotroph adenomas
-
Bertherat J, Chanson P, Montminy M. The cyclic adenosine 3,5-monophosphate-responsive factor CREB is constitutively activated in human somatotroph adenomas. Mol. Endocrinol. 9(7), 777-783 (1995).
-
(1995)
Mol. Endocrinol.
, vol.9
, Issue.7
, pp. 777-783
-
-
Bertherat, J.1
Chanson, P.2
Montminy, M.3
-
44
-
-
34547526773
-
Gsa overexpression and loss of Gsa imprinting in human somatotroph adenomas: Association with tumor size and response to pharmacologic treatment
-
Picard C, Silvy M, Gerard C et al. Gsa overexpression and loss of Gsa imprinting in human somatotroph adenomas: association with tumor size and response to pharmacologic treatment. Int. J. Cancer 121(6), 1245-1252 (2007).
-
(2007)
Int. J. Cancer
, vol.121
, Issue.6
, pp. 1245-1252
-
-
Picard, C.1
Silvy, M.2
Gerard, C.3
-
45
-
-
0025695763
-
Clinical, biochemical, and morphological correlates in patients bearing growth hormone-secreting pituitary tumors with or without constitutively active adenylyl cyclase
-
Spada A, Arosio M, Bochicchio D et al. Clinical, biochemical, and morphological correlates in patients bearing growth hormone-secreting pituitary tumors with or without constitutively active adenylyl cyclase. J. Clin. Endocrinol. Metab. 71(6), 1421-1426 (1990).
-
(1990)
J. Clin. Endocrinol. Metab.
, vol.71
, Issue.6
, pp. 1421-1426
-
-
Spada, A.1
Arosio, M.2
Bochicchio, D.3
-
46
-
-
59849084828
-
Non-functioning pituitary adenomas infrequently harbor G-protein gene mutations
-
Ruggeri RM, Santarpia L, Curtò L et al. Non-functioning pituitary adenomas infrequently harbor G-protein gene mutations J. Endocrinol. Invest. 31(11), 946-949 (2008).
-
(2008)
J. Endocrinol. Invest.
, vol.31
, Issue.11
, pp. 946-949
-
-
Ruggeri, R.M.1
Santarpia, L.2
Curtò, L.3
-
47
-
-
0034880394
-
Relevant cAMP-specific phosphodiesterase isoforms in human pituitary: Effect of Gs(a) mutations
-
Persani L, Borgato S, Lania A et al. Relevant cAMP-specific phosphodiesterase isoforms in human pituitary: effect of Gs(a) mutations. J. Clin. Endocrinol. Metab. 86(8), 3795-3800 (2001).
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, Issue.8
, pp. 3795-3800
-
-
Persani, L.1
Borgato, S.2
Lania, A.3
-
48
-
-
3042547294
-
Protein kinase A and its role in human neoplasia: The Carney complex paradigm
-
Bossis I, Voutetakis A, Bei T, Sandrini F, Griffin KJ, Stratakis CA. Protein kinase A and its role in human neoplasia: the Carney complex paradigm. Endocr. Relat. Cancer 11(2), 265-280 (2004).
-
(2004)
Endocr. Relat. Cancer
, vol.11
, Issue.2
, pp. 265-280
-
-
Bossis, I.1
Voutetakis, A.2
Bei, T.3
Sandrini, F.4
Griffin, K.J.5
Stratakis, C.A.6
-
49
-
-
0033812849
-
Mutations of the gene encoding the protein kinase A type I-a regulatory subunit in patients with the Carney complex
-
Kirschner LS, Carney JA, Pack SD et al. Mutations of the gene encoding the protein kinase A type I-a regulatory subunit in patients with the Carney complex. Nat. Genet. 26(1), 89-92 (2000).
-
(2000)
Nat. Genet.
, vol.26
, Issue.1
, pp. 89-92
-
-
Kirschner, L.S.1
Carney, J.A.2
Pack, S.D.3
-
50
-
-
66749184725
-
Mutations in regulatory subunit type 1A of cyclic adenosine 5-monophosphate-dependent protein kinase (PRKAR1A): Phenotype analysis in 353 patients and 80 different genotypes
-
Bertherat J, Horvath A, Groussin L et al. Mutations in regulatory subunit type 1A of cyclic adenosine 5-monophosphate-dependent protein kinase (PRKAR1A): phenotype analysis in 353 patients and 80 different genotypes. J. Clin. Endocrinol. Metab. 94(6), 2085-2091 (2009).
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, Issue.6
, pp. 2085-2091
-
-
Bertherat, J.1
Horvath, A.2
Groussin, L.3
-
51
-
-
0033767048
-
Genetic and histologic studies of somatomammotropic pituitary tumors in patients with the "complex of spotty skin pigmentation, myxomas, endocrine overactivity and schwannomas" (Carney complex)
-
Pack SD, Kirschner LS, Pak E, Zhuang Z, Carney JA, Stratakis CA. Genetic and histologic studies of somatomammotropic pituitary tumors in patients with the "complex of spotty skin pigmentation, myxomas, endocrine overactivity and schwannomas" (Carney complex). J. Clin. Endocrinol. Metab. 85(10), 3860-3865 (2000).
-
(2000)
J. Clin. Endocrinol. Metab.
, vol.85
, Issue.10
, pp. 3860-3865
-
-
Pack, S.D.1
Kirschner, L.S.2
Pak, E.3
Zhuang, Z.4
Carney, J.A.5
Stratakis, C.A.6
-
52
-
-
14944365414
-
Pituitary pathology in Carney complex patients
-
Stergiopoulos SG, Abu-Asab MS, Tsokos M, Stratakis CA. Pituitary pathology in Carney complex patients. Pituitary 7(2), 73-82 (2004).
-
(2004)
Pituitary
, vol.7
, Issue.2
, pp. 73-82
-
-
Stergiopoulos, S.G.1
Abu-Asab, M.S.2
Tsokos, M.3
Stratakis, C.A.4
-
53
-
-
33646242246
-
Cortisol and growth hormone: Clinical implications of a complex, dynamic relationship
-
Stratakis CA. Cortisol and growth hormone: clinical implications of a complex, dynamic relationship. Pediatr. Endocrinol. Rev. 3(Suppl. 2), 333-338 (2006).
-
(2006)
Pediatr. Endocrinol. Rev.
, vol.3
, Issue.SUPPL. 2
, pp. 333-338
-
-
Stratakis, C.A.1
-
54
-
-
84865086604
-
Advances in the diagnosis, treatment, and molecular genetics of pituitary adenomas in childhood
-
Keil MF, Stratakis CA. Advances in the diagnosis, treatment, and molecular genetics of pituitary adenomas in childhood. US Endocrinol. 4(2), 81-85 (2009).
-
(2009)
US Endocrinol.
, vol.4
, Issue.2
, pp. 81-85
-
-
Keil, M.F.1
Stratakis, C.A.2
-
55
-
-
0036886062
-
PRKAR1A, one of the Carney complex genes, and its locus (17q22-24) are rarely altered in pituitary tumours outside the Carney complex
-
Sandrini F, Kirschner LS, Bei T et al. PRKAR1A, one of the Carney complex genes, and its locus (17q22-24) are rarely altered in pituitary tumours outside the Carney complex. J. Med. Genet. 39(12), e78 (2002).
-
(2002)
J. Med. Genet.
, vol.39
, Issue.12
-
-
Sandrini, F.1
Kirschner, L.S.2
Bei, T.3
-
56
-
-
0038359744
-
Effects of hypothalamic neuropeptides on extracellular signal-regulated kinase (ERK1 and ERK2) cascade in human tumoral pituitary cells
-
Lania A, Filopanti M, Corbetta S et al. Effects of hypothalamic neuropeptides on extracellular signal-regulated kinase (ERK1 and ERK2) cascade in human tumoral pituitary cells. J. Clin. Endocrinol. Metab. 88(4), 1692-1696 (2003).
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, Issue.4
, pp. 1692-1696
-
-
Lania, A.1
Filopanti, M.2
Corbetta, S.3
-
57
-
-
28744433844
-
Effect of cyclic adenosine 3,5-monophosphate/protein kinase a pathway on markers of cell proliferation in nonfunctioning pituitary adenomas
-
Mantovani G, Bondioni S, Ferrero S et al. Effect of cyclic adenosine 3,5-monophosphate/protein kinase a pathway on markers of cell proliferation in nonfunctioning pituitary adenomas. J. Clin. Endocrinol. Metab. 90(12), 6721-6724 (2005).
-
(2005)
J. Clin. Endocrinol. Metab.
, vol.90
, Issue.12
, pp. 6721-6724
-
-
Mantovani, G.1
Bondioni, S.2
Ferrero, S.3
-
58
-
-
0035282334
-
Mammalian MAP kinase signalling cascades
-
Chang L, Karin M. Mammalian MAP kinase signalling cascades. Nature 410(6824), 37-40 (2001).
-
(2001)
Nature
, vol.410
, Issue.6824
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
59
-
-
34248597065
-
Differential regulation and properties of MAPKs
-
Raman M, Chen W, Cobb MH. Differential regulation and properties of MAPKs. Oncogene 26(22), 3100-3112 (2007).
-
(2007)
Oncogene
, vol.26
, Issue.22
, pp. 3100-3112
-
-
Raman, M.1
Chen, W.2
Cobb, M.H.3
-
60
-
-
34248575149
-
Integrating signals from RTKs to ERK/MAPK
-
McKay MM, Morrison DK. Integrating signals from RTKs to ERK/MAPK. Oncogene 26(22), 3113-3121 (2007).
-
(2007)
Oncogene
, vol.26
, Issue.22
, pp. 3113-3121
-
-
McKay, M.M.1
Morrison, D.K.2
-
61
-
-
0037188868
-
Signal transduction. MAP kinase signaling specificity
-
Weston CR, Lambright DG, Davis RJ. Signal transduction. MAP kinase signaling specificity. Science 296(5577), 2345-2347 (2002).
-
(2002)
Science
, vol.296
, Issue.5577
, pp. 2345-2347
-
-
Weston, C.R.1
Lambright, D.G.2
Davis, R.J.3
-
62
-
-
33744974769
-
Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression
-
Yamamoto T, Ebisuya M, Ashida F, Okamoto K, Yonehara S, Nishida E. Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression. Curr. Biol. 16(12), 1171-1182 (2006).
-
(2006)
Curr. Biol.
, vol.16
, Issue.12
, pp. 1171-1182
-
-
Yamamoto, T.1
Ebisuya, M.2
Ashida, F.3
Okamoto, K.4
Yonehara, S.5
Nishida, E.6
-
63
-
-
0036607064
-
Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation
-
Stork PJ, Schmitt JM. Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation. Trends Cell Biol. 12(6), 258-266 (2002).
-
(2002)
Trends Cell Biol.
, vol.12
, Issue.6
, pp. 258-266
-
-
Stork, P.J.1
Schmitt, J.M.2
-
64
-
-
0032929762
-
Signalling through phosphoinositide 3-kinases: The lipids take centre stage
-
Leevers SJ, Vanhaesebroeck B, Waterfield MD. Signalling through phosphoinositide 3-kinases: the lipids take centre stage. Curr. Opin. Cell Biol. 11(2), 219-225 (1999).
-
(1999)
Curr. Opin. Cell Biol.
, vol.11
, Issue.2
, pp. 219-225
-
-
Leevers, S.J.1
Vanhaesebroeck, B.2
Waterfield, M.D.3
-
65
-
-
51849084360
-
The PTEN-PI3K pathway: of feedbacks and cross-talks
-
Carracedo A, Pandolfi PP. The PTEN-PI3K pathway: of feedbacks and cross-talks. Oncogene 27(41), 5527-5541 (2008).
-
(2008)
Oncogene
, vol.27
, Issue.41
, pp. 5527-5541
-
-
Carracedo, A.1
Pandolfi, P.P.2
-
66
-
-
33745327045
-
Back to the roots: The remarkable RAF oncogene story
-
Zebisch A, Troppmair J. Back to the roots: the remarkable RAF oncogene story. Cell. Mol. Life Sci. 63(11), 1314-1330 (2006).
-
(2006)
Cell. Mol. Life Sci.
, vol.63
, Issue.11
, pp. 1314-1330
-
-
Zebisch, A.1
Troppmair, J.2
-
67
-
-
34248583886
-
MAP kinase signalling pathways in cancer
-
Dhillon AS, Hagan S, Rath O, Kolch W. MAP kinase signalling pathways in cancer. Oncogene 26(22), 3279-3290 (2007).
-
(2007)
Oncogene
, vol.26
, Issue.22
, pp. 3279-3290
-
-
Dhillon, A.S.1
Hagan, S.2
Rath, O.3
Kolch, W.4
-
68
-
-
4544266128
-
IGF-I inhibits apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway in pituitary cells
-
Fernandez M, Sanchez-Franco F, Palacios N, Sanchez I, Fernandez C, Cacicedo L. IGF-I inhibits apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway in pituitary cells. J. Mol. Endocrinol. 33(1), 155-163 (2004).
-
(2004)
J. Mol. Endocrinol.
, vol.33
, Issue.1
, pp. 155-163
-
-
Fernandez, M.1
Sanchez-Franco, F.2
Palacios, N.3
Sanchez, I.4
Fernandez, C.5
Cacicedo, L.6
-
69
-
-
0038348294
-
Involvement of vasoactive intestinal peptide on insulin-like growth factor I-induced proliferation of rat pituitary lactotropes in primary culture: Evidence for an autocrine and/or paracrine regulatory system
-
Fernandez M, Sanchez-Franco F, Palacios N, Sanchez I, Villuendas G, Cacicedo L. Involvement of vasoactive intestinal peptide on insulin-like growth factor I-induced proliferation of rat pituitary lactotropes in primary culture: evidence for an autocrine and/or paracrine regulatory system. Neuroendocrinology 77(5), 341-352 (2003).
-
(2003)
Neuroendocrinology
, vol.77
, Issue.5
, pp. 341-352
-
-
Fernandez, M.1
Sanchez-Franco, F.2
Palacios, N.3
Sanchez, I.4
Villuendas, G.5
Cacicedo, L.6
-
70
-
-
34250840807
-
Conditional overexpression of the wild-type Gs a as the GSP oncogene initiates chronic extracellularly regulated kinase 1/2 activation and hormone hypersecretion in pituitary cell lines
-
Romano D, Magalon K, Pertuit M et al. Conditional overexpression of the wild-type Gs a as the GSP oncogene initiates chronic extracellularly regulated kinase 1/2 activation and hormone hypersecretion in pituitary cell lines. Endocrinology 148(6), 2973-2983 (2007).
-
(2007)
Endocrinology
, vol.148
, Issue.6
, pp. 2973-2983
-
-
Romano, D.1
Magalon, K.2
Pertuit, M.3
-
71
-
-
65549088020
-
Frequent mutations and amplifications of the PIK3CA gene in pituitary tumors
-
Lin Y, Jiang X, Shen Y et al. Frequent mutations and amplifications of the PIK3CA gene in pituitary tumors. Endocr. Relat. Cancer 16(1), 301-310 (2009).
-
(2009)
Endocr. Relat. Cancer
, vol.16
, Issue.1
, pp. 301-310
-
-
Lin, Y.1
Jiang, X.2
Shen, Y.3
-
72
-
-
33846930599
-
A mutation and expression analysis of the oncogene BRAF in pituitary adenomas
-
Ewing I, Pedder-Smith S, Franchi G et al. A mutation and expression analysis of the oncogene BRAF in pituitary adenomas. Clin. Endocrinol. (Oxf.) 66(3), 348-352 (2007).
-
(2007)
Clin. Endocrinol. (Oxf.)
, vol.66
, Issue.3
, pp. 348-352
-
-
Ewing, I.1
Pedder-Smith, S.2
Franchi, G.3
-
73
-
-
21244498552
-
Enhanced protein kinase B/Akt signalling in pituitary tumours
-
Musat M, Korbonits M, Kola B et al. Enhanced protein kinase B/Akt signalling in pituitary tumours. Endocr. Relat. Cancer 12(2), 423-433 (2005).
-
(2005)
Endocr. Relat. Cancer
, vol.12
, Issue.2
, pp. 423-433
-
-
Musat, M.1
Korbonits, M.2
Kola, B.3
-
74
-
-
0032531169
-
Multiple endocrine neoplasia type 1: Clinical and genetic topics
-
Marx S, Spiegel AM, Skarulis MC, Doppman JL, Collins FS, Liotta LA. Multiple endocrine neoplasia type 1: clinical and genetic topics. Ann. Intern. Med. 129(6), 484-494 (1998).
-
(1998)
Ann. Intern. Med.
, vol.129
, Issue.6
, pp. 484-494
-
-
Marx, S.1
Spiegel, A.M.2
Skarulis, M.C.3
Doppman, J.L.4
Collins, F.S.5
Liotta, L.A.6
-
75
-
-
22444445436
-
Menin molecular interactions: Insights into normal functions and tumorigenesis
-
Agarwal SK, Kennedy PA, Scacheri PC et al. Menin molecular interactions: insights into normal functions and tumorigenesis. Horm. Metab. Res. 37(6), 369-374 (2005).
-
(2005)
Horm. Metab. Res.
, vol.37
, Issue.6
, pp. 369-374
-
-
Agarwal, S.K.1
Kennedy, P.A.2
Scacheri, P.C.3
-
76
-
-
20044380143
-
Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors
-
Milne TA, Hughes CM, Lloyd R et al. Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors. Proc. Natl Acad. Sci. USA 102(3), 749-754 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, Issue.3
, pp. 749-754
-
-
Milne, T.A.1
Hughes, C.M.2
Lloyd, R.3
-
77
-
-
38149112594
-
Multiple endocrine neoplasia type 1 (MEN1): Analysis of 1336 mutations reported in the first decade following identification of the gene
-
Lemos MC, Thakker RV. Multiple endocrine neoplasia type 1 (MEN1): analysis of 1336 mutations reported in the first decade following identification of the gene. Hum. Mutat. 29(1), 22-32 (2008).
-
(2008)
Hum. Mutat.
, vol.29
, Issue.1
, pp. 22-32
-
-
Lemos, M.C.1
Thakker, R.V.2
-
78
-
-
0038357688
-
The treatment of sporadic versus MEN1-related pituitary adenomas
-
Beckers A, Betea D, Valdes Socin H, Stevenaert A. The treatment of sporadic versus MEN1-related pituitary adenomas. J. Intern. Med. 253(6), 599-605 (2003).
-
(2003)
J. Intern. Med.
, vol.253
, Issue.6
, pp. 599-605
-
-
Beckers, A.1
Betea, D.2
Valdes Socin, H.3
Stevenaert, A.4
-
79
-
-
3042587437
-
Differential expression of menin in sporadic pituitary adenomas
-
Theodoropoulou M, Cavallari I, Barzon L et al. Differential expression of menin in sporadic pituitary adenomas. Endocr. Relat. Cancer 11(2), 333-344 (2004).
-
(2004)
Endocr. Relat. Cancer
, vol.11
, Issue.2
, pp. 333-344
-
-
Theodoropoulou, M.1
Cavallari, I.2
Barzon, L.3
-
80
-
-
34249860559
-
The parathyroid/pituitary variant of multiple endocrine neoplasia type 1 usually has causes other than p27Kip1 mutations
-
Ozawa A, Agarwal SK, Mateo CM et al. The parathyroid/pituitary variant of multiple endocrine neoplasia type 1 usually has causes other than p27Kip1 mutations. J. Clin. Endocrinol. Metab. 92(5), 1948-1951 (2007).
-
(2007)
J. Clin. Endocrinol. Metab.
, vol.92
, Issue.5
, pp. 1948-1951
-
-
Ozawa, A.1
Agarwal, S.K.2
Mateo, C.M.3
-
81
-
-
0036606022
-
Recessive transmission of a multiple endocrine neoplasia syndrome in the rat
-
Fritz A, Walch A, Piotrowska K et al. Recessive transmission of a multiple endocrine neoplasia syndrome in the rat. Cancer Res. 62(11), 3048-3051 (2002).
-
(2002)
Cancer Res.
, vol.62
, Issue.11
, pp. 3048-3051
-
-
Fritz, A.1
Walch, A.2
Piotrowska, K.3
-
82
-
-
84925867392
-
Genetic factors in the development of pituitary adenomas
-
Vandeva S, Tichomirowa MA, Zacharieva S, Daly AF, Beckers A. Genetic factors in the development of pituitary adenomas. Endocr. Dev. 17, 121-133 (2010).
-
(2010)
Endocr. Dev.
, vol.17
, pp. 121-133
-
-
Vandeva, S.1
Tichomirowa, M.A.2
Zacharieva, S.3
Daly, A.F.4
Beckers, A.5
-
83
-
-
0030840987
-
Transforming growth factor-b, transforming growth factor-b receptor II, and p27Kip1 expression in nontumorous and neoplastic human pituitaries
-
Jin L, Qian X, Kulig E et al. Transforming growth factor-b, transforming growth factor-b receptor II, and p27Kip1 expression in nontumorous and neoplastic human pituitaries. Am. J. Pathol. 151(2), 509-519 (1997).
-
(1997)
Am. J. Pathol.
, vol.151
, Issue.2
, pp. 509-519
-
-
Jin, L.1
Qian, X.2
Kulig, E.3
-
84
-
-
18444413232
-
Expression of phosphorylated p27(Kip1) protein and Jun activation domain-binding protein 1 in human pituitary tumors
-
Korbonits M, Chahal HS, Kaltsas G et al. Expression of phosphorylated p27(Kip1) protein and Jun activation domain-binding protein 1 in human pituitary tumors. J. Clin. Endocrinol. Metab. 87(6), 2635-2643 (2002).
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, Issue.6
, pp. 2635-2643
-
-
Korbonits, M.1
Chahal, H.S.2
Kaltsas, G.3
-
85
-
-
0033123107
-
Familial acromegaly: Case report and review of the literature
-
Verloes A, Stevenaert A, Teh BT, Petrossians P, Beckers A. Familial acromegaly: case report and review of the literature. Pituitary 1(3-4), 273-277 (1999).
-
(1999)
Pituitary
, vol.1
, Issue.3-4
, pp. 273-277
-
-
Verloes, A.1
Stevenaert, A.2
Teh, B.T.3
Petrossians, P.4
Beckers, A.5
-
86
-
-
45149085453
-
The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas
-
Leontiou CA, Gueorguiev M, van der Spuy J et al. The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas. J. Clin. Endocrinol. Metab. 93(6), 2390-2401 (2008).
-
(2008)
J. Clin. Endocrinol. Metab.
, vol.93
, Issue.6
, pp. 2390-2401
-
-
Leontiou, C.A.1
Gueorguiev, M.2
Van Der Spuy, J.3
-
87
-
-
66749101229
-
Genetic, molecular and clinical features of familial isolated pituitary adenomas
-
Daly AF, Tichomirowa MA, Beckers A. Genetic, molecular and clinical features of familial isolated pituitary adenomas. Horm. Res. 71(Suppl. 2), 116-122 (2009).
-
(2009)
Horm. Res.
, vol.71
, Issue.SUPPL. 2
, pp. 116-122
-
-
Daly, A.F.1
Tichomirowa, M.A.2
Beckers, A.3
-
88
-
-
33748742372
-
Clinical characterization of familial isolated pituitary adenomas
-
Daly AF, Jaffrain-Rea ML, Ciccarelli A et al. Clinical characterization of familial isolated pituitary adenomas. J. Clin. Endocrinol. Metab. 91(9), 3316-3323 (2006).
-
(2006)
J. Clin. Endocrinol. Metab.
, vol.91
, Issue.9
, pp. 3316-3323
-
-
Daly, A.F.1
Jaffrain-Rea, M.L.2
Ciccarelli, A.3
-
89
-
-
34249844498
-
Mutations in the aryl hydrocarbon receptor interacting protein gene are not highly prevalent among subjects with sporadic pituitary adenomas
-
Barlier A, Vanbellinghen JF, Daly AF et al. Mutations in the aryl hydrocarbon receptor interacting protein gene are not highly prevalent among subjects with sporadic pituitary adenomas. J. Clin. Endocrinol. Metab. 92(5), 1952-1955 (2007).
-
(2007)
J. Clin. Endocrinol. Metab.
, vol.92
, Issue.5
, pp. 1952-1955
-
-
Barlier, A.1
Vanbellinghen, J.F.2
Daly, A.F.3
-
90
-
-
0030910680
-
Isolation and characterization of a pituitary tumor-transforming gene (PTTG)
-
Pei L, Melmed S. Isolation and characterization of a pituitary tumor-transforming gene (PTTG). Mol. Endocrinol. 11(4), 433-441 (1997).
-
(1997)
Mol. Endocrinol.
, vol.11
, Issue.4
, pp. 433-441
-
-
Pei, L.1
Melmed, S.2
-
91
-
-
53849096004
-
Pituitary tumor-transforming gene in endocrine and other neoplasms: A review and update
-
Salehi F, Kovacs K, Scheithauer BW, Lloyd RV, Cusimano M. Pituitary tumor-transforming gene in endocrine and other neoplasms: a review and update. Endocr. Relat. Cancer 15(3), 721-743 (2008).
-
(2008)
Endocr. Relat. Cancer
, vol.15
, Issue.3
, pp. 721-743
-
-
Salehi, F.1
Kovacs, K.2
Scheithauer, B.W.3
Lloyd, R.V.4
Cusimano, M.5
-
92
-
-
17844400784
-
Early multipotential pituitary focal hyperplasia in the a-subunit of glycoprotein hormone-driven pituitary tumor-transforming gene transgenic mice
-
Abbud RA, Takumi I, Barker EM et al. Early multipotential pituitary focal hyperplasia in the a-subunit of glycoprotein hormone-driven pituitary tumor-transforming gene transgenic mice. Mol. Endocrinol. 19(5), 1383-1391 (2005).
-
(2005)
Mol. Endocrinol.
, vol.19
, Issue.5
, pp. 1383-1391
-
-
Abbud, R.A.1
Takumi, I.2
Barker, E.M.3
-
93
-
-
0023157363
-
Angiogenic factors
-
Folkman J, Klagsbrun M. Angiogenic factors. Science 235(4787), 442-447 (1987).
-
(1987)
Science
, vol.235
, Issue.4787
, pp. 442-447
-
-
Folkman, J.1
Klagsbrun, M.2
-
95
-
-
33845922655
-
P21 delays tumor onset by preservation of chromosomal stability
-
Barboza JA, Liu G, Ju Z, El-Naggar AK, Lozano G. p21 delays tumor onset by preservation of chromosomal stability. Proc. Natl Acad. Sci. USA 103(52), 19842-19847 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.52
, pp. 19842-19847
-
-
Barboza, J.A.1
Liu, G.2
Ju, Z.3
El-Naggar, A.K.4
Lozano, G.5
-
96
-
-
25444437196
-
ATM and p21 cooperate to suppress aneuploidy and subsequent tumor development
-
Shen KC, Heng H, Wang Y et al. ATM and p21 cooperate to suppress aneuploidy and subsequent tumor development. Cancer Res. 65(19), 8747-8753 (2005).
-
(2005)
Cancer Res.
, vol.65
, Issue.19
, pp. 8747-8753
-
-
Shen, K.C.1
Heng, H.2
Wang, Y.3
-
97
-
-
33748422079
-
Oncogene-induced cell senescence - Halting on the road to cancer
-
Mooi WJ, Peeper DS. Oncogene-induced cell senescence - halting on the road to cancer. N. Engl. J. Med. 355(10), 1037-1046 (2006).
-
(2006)
N. Engl. J. Med.
, vol.355
, Issue.10
, pp. 1037-1046
-
-
Mooi, W.J.1
Peeper, D.S.2
-
98
-
-
35948990011
-
Senescence mediates pituitary hypoplasia and restrains pituitary tumor growth
-
Chesnokova V, Zonis S, Rubinek T et al. Senescence mediates pituitary hypoplasia and restrains pituitary tumor growth. Cancer Res. 67(21), 10564-10572 (2007).
-
(2007)
Cancer Res.
, vol.67
, Issue.21
, pp. 10564-10572
-
-
Chesnokova, V.1
Zonis, S.2
Rubinek, T.3
-
99
-
-
27144512029
-
Aneuploidy, centrosome alteration and securin overexpression as features of pituitary somatotroph and lactotroph adenomas
-
Uccella S, Tibiletti MG, Bernasconi B, Finzi G, Oldrini R, Capella C. Aneuploidy, centrosome alteration and securin overexpression as features of pituitary somatotroph and lactotroph adenomas. Anal. Quant. Cytol. Histol. 27(5), 241-252 (2005).
-
(2005)
Anal. Quant. Cytol. Histol.
, vol.27
, Issue.5
, pp. 241-252
-
-
Uccella, S.1
Tibiletti, M.G.2
Bernasconi, B.3
Finzi, G.4
Oldrini, R.5
Capella, C.6
-
100
-
-
72349092960
-
Influence of growth and transcriptional factors, and signaling molecules on early human pituitary development
-
Bazina M, Vukojevic K, Roje D, Saraga- Babic M. Influence of growth and transcriptional factors, and signaling molecules on early human pituitary development. J. Mol. Histol. 40(4), 277-286 (2009).
-
(2009)
J. Mol. Histol.
, vol.40
, Issue.4
, pp. 277-286
-
-
Bazina, M.1
Vukojevic, K.2
Roje, D.3
Saraga- Babic, M.4
-
101
-
-
0029122724
-
Targeting of transforming growth factor-a expression to pituitary lactotrophs in transgenic mice results in selective lactotroph proliferation and adenomas
-
McAndrew J, Paterson AJ, Asa SL, McCarthy KJ, Kudlow JE. Targeting of transforming growth factor-a expression to pituitary lactotrophs in transgenic mice results in selective lactotroph proliferation and adenomas. Endocrinology 136(10), 4479-4488 (1995).
-
(1995)
Endocrinology
, vol.136
, Issue.10
, pp. 4479-4488
-
-
McAndrew, J.1
Paterson, A.J.2
Asa, S.L.3
McCarthy, K.J.4
Kudlow, J.E.5
-
102
-
-
0030064976
-
Epidermal growth factor and its receptor (EGF-R) in human pituitary adenomas: EGF-R correlates with tumor aggressiveness
-
LeRiche VK, Asa SL, Ezzat S. Epidermal growth factor and its receptor (EGF-R) in human pituitary adenomas: EGF-R correlates with tumor aggressiveness. J. Clin. Endocrinol. Metab. 81(2), 656-662 (1996).
-
(1996)
J. Clin. Endocrinol. Metab.
, vol.81
, Issue.2
, pp. 656-662
-
-
Leriche, V.K.1
Asa, S.L.2
Ezzat, S.3
-
103
-
-
0034443475
-
Expression of growth factors in normal and neoplastic pituitary tissues
-
Saeger W. Expression of growth factors in normal and neoplastic pituitary tissues. Endocr. Pathol. 11(4), 295-300 (2000).
-
(2000)
Endocr. Pathol.
, vol.11
, Issue.4
, pp. 295-300
-
-
Saeger, W.1
-
104
-
-
0036144332
-
Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis
-
Ezzat S, Zheng L, Zhu XF, Wu GE, Asa SL. Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis. J. Clin. Invest. 109(1), 69-78 (2002).
-
(2002)
J. Clin. Invest.
, vol.109
, Issue.1
, pp. 69-78
-
-
Ezzat, S.1
Zheng, L.2
Zhu, X.F.3
Wu, G.E.4
Asa, S.L.5
-
105
-
-
39149111949
-
Expression of pituitary tumour-derived, N-terminally truncated isoform of fibroblast growth factor receptor 4 (ptd-FGFR4) correlates with tumour invasiveness but not with G-protein a subunit (GSP) mutation in human GH-secreting pituitary adenomas
-
Morita K, Takano K, Yasufuku-Takano J et al. Expression of pituitary tumour-derived, N-terminally truncated isoform of fibroblast growth factor receptor 4 (ptd-FGFR4) correlates with tumour invasiveness but not with G-protein a subunit (GSP) mutation in human GH-secreting pituitary adenomas. Clin. Endocrinol. (Oxf.) 68(3), 435-441 (2008).
-
(2008)
Clin. Endocrinol. (Oxf.)
, vol.68
, Issue.3
, pp. 435-441
-
-
Morita, K.1
Takano, K.2
Yasufuku-Takano, J.3
-
106
-
-
0034574298
-
How cells read TGF-b signals
-
Massague J. How cells read TGF-b signals. Nat. Rev. Mol. Cell Biol. 1(3), 169-178 (2000).
-
(2000)
Nat. Rev. Mol. Cell Biol.
, vol.1
, Issue.3
, pp. 169-178
-
-
Massague, J.1
-
107
-
-
0032029606
-
Signal transduction by bone morphogenetic proteins
-
DOI 10.1016/S1359-6101(97)00036-1, PII S1359610197000361
-
Kawabata M, Imamura T, Miyazono K. Signal transduction by bone morphogenetic proteins. Cytokine Growth Factor Rev. 9(1), 49-61 (1998). (Pubitemid 28280536)
-
(1998)
Cytokine and Growth Factor Reviews
, vol.9
, Issue.1
, pp. 49-61
-
-
Kawabata, M.1
Imamura, T.2
Miyazono, K.3
-
108
-
-
0034021776
-
Bone morphogenetic protein receptor complexes on the surface of live cells: A new oligomerization mode for serine/threonine kinase receptors
-
Gilboa L, Nohe A, Geissendorfer T, Sebald W, Henis YI, Knaus P. Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors. Mol. Biol. Cell 11(3), 1023-1035 (2000).
-
(2000)
Mol. Biol. Cell
, vol.11
, Issue.3
, pp. 1023-1035
-
-
Gilboa, L.1
Nohe, A.2
Geissendorfer, T.3
Sebald, W.4
Henis, Y.I.5
Knaus, P.6
-
109
-
-
0031438047
-
TGF-b signalling from cell membrane to nucleus through SMAD proteins
-
Heldin CH, Miyazono K, ten Dijke P. TGF-b signalling from cell membrane to nucleus through SMAD proteins. Nature 390(6659), 465-471 (1997).
-
(1997)
Nature
, vol.390
, Issue.6659
, pp. 465-471
-
-
Heldin, C.H.1
Miyazono, K.2
Ten Dijke, P.3
-
110
-
-
70350338075
-
Regulation of pituitary function by cytokines
-
Haedo MR, Gerez J, Fuertes M et al. Regulation of pituitary function by cytokines. Horm. Res. 72(5), 266-274 (2009).
-
(2009)
Horm. Res.
, vol.72
, Issue.5
, pp. 266-274
-
-
Haedo, M.R.1
Gerez, J.2
Fuertes, M.3
-
111
-
-
33745802641
-
Bone morphogenetic protein-4 control of pituitary pathophysiology
-
Giacomini D, Paez-Pereda M, Theodoropoulou M et al. Bone morphogenetic protein-4 control of pituitary pathophysiology. Front. Horm. Res. 35, 22-31 (2006).
-
(2006)
Front. Horm. Res.
, vol.35
, pp. 22-31
-
-
Giacomini, D.1
Paez-Pereda, M.2
Theodoropoulou, M.3
-
112
-
-
0037417805
-
Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen receptor crosstalk
-
Paez-Pereda M, Giacomini D, Refojo D et al. Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen receptor crosstalk. Proc. Natl Acad. Sci. USA 100(3), 1034-1039 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, Issue.3
, pp. 1034-1039
-
-
Paez-Pereda, M.1
Giacomini, D.2
Refojo, D.3
-
113
-
-
66749133395
-
Differential gene expression in models of pituitary prolactin-producing tumoral cells
-
Giacomini D, Haedo M, Gerez J et al. Differential gene expression in models of pituitary prolactin-producing tumoral cells. Horm. Res. 71(Suppl. 2), 88-94 (2009).
-
(2009)
Horm. Res.
, vol.71
, Issue.SUPPL. 2
, pp. 88-94
-
-
Giacomini, D.1
Haedo, M.2
Gerez, J.3
-
114
-
-
0032700248
-
The biologic basis for the use of retinoids in cancer prevention and treatment
-
Kurie JM. The biologic basis for the use of retinoids in cancer prevention and treatment. Curr. Opin Oncol. 11(6), 497-502 (1999).
-
(1999)
Curr. Opin Oncol.
, vol.11
, Issue.6
, pp. 497-502
-
-
Kurie, J.M.1
-
115
-
-
0034776771
-
Retinoic acid prevents experimental Cushing syndrome
-
Paez-Pereda M, Kovalovsky D, Hopfner U et al. Retinoic acid prevents experimental Cushing syndrome. J. Clin. Invest. 108(8), 1123-1131 (2001).
-
(2001)
J. Clin. Invest.
, vol.108
, Issue.8
, pp. 1123-1131
-
-
Paez-Pereda, M.1
Kovalovsky, D.2
Hopfner, U.3
-
116
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg RA. The retinoblastoma protein and cell cycle control. Cell 81(3), 323-330 (1995).
-
(1995)
Cell
, vol.81
, Issue.3
, pp. 323-330
-
-
Weinberg, R.A.1
-
117
-
-
0026702996
-
Effects of an Rb mutation in the mouse
-
Jacks T, Fazeli A, Schmitt EM, Bronson RT, Goodell MA, Weinberg RA. Effects of an Rb mutation in the mouse. Nature 359(6393), 295-300 (1992).
-
(1992)
Nature
, vol.359
, Issue.6393
, pp. 295-300
-
-
Jacks, T.1
Fazeli, A.2
Schmitt, E.M.3
Bronson, R.T.4
Goodell, M.A.5
Weinberg, R.A.6
-
118
-
-
0038608891
-
Human pituitary adenomas infrequently contain inactivation of retinoblastoma 1 gene and activation of cyclin dependent kinase 4 gene
-
Honda S, Tanaka-Kosugi C, Yamada S et al. Human pituitary adenomas infrequently contain inactivation of retinoblastoma 1 gene and activation of cyclin dependent kinase 4 gene. Endocr. J. 50(3), 309-318 (2003).
-
(2003)
Endocr. J.
, vol.50
, Issue.3
, pp. 309-318
-
-
Honda, S.1
Tanaka-Kosugi, C.2
Yamada, S.3
-
119
-
-
0034161905
-
Loss of pRb expression in pituitary adenomas is associated with methylation of the Rb1 CpG island
-
Simpson DJ, Hibberts NA, McNicol AM, Clayton RN, Farrell WE. Loss of pRb expression in pituitary adenomas is associated with methylation of the Rb1 CpG island. Cancer Res. 60(5), 1211-1216 (2000).
-
(2000)
Cancer Res.
, vol.60
, Issue.5
, pp. 1211-1216
-
-
Simpson, D.J.1
Hibberts, N.A.2
McNicol, A.M.3
Clayton, R.N.4
Farrell, W.E.5
-
120
-
-
34248993306
-
Promoter hypermethylation profile of cell cycle regulator genes in pituitary adenomas
-
Yoshino A, Katayama Y, Ogino A et al. Promoter hypermethylation profile of cell cycle regulator genes in pituitary adenomas. J. Neurooncol. 83(2), 153-162 (2007).
-
(2007)
J. Neurooncol.
, vol.83
, Issue.2
, pp. 153-162
-
-
Yoshino, A.1
Katayama, Y.2
Ogino, A.3
-
121
-
-
77952751782
-
Role of the high mobility group A (HMGA) proteins in the regulation of pituitary cell cycle
-
Fedele M, Fusco A. Role of the high mobility group A (HMGA) proteins in the regulation of pituitary cell cycle. J. Mol. Endocrinol. 44(6), 309-118 (2010).
-
(2010)
J. Mol. Endocrinol.
, vol.44
, Issue.6
, pp. 309-118
-
-
Fedele, M.1
Fusco, A.2
-
122
-
-
36448992338
-
Roles of HMGA proteins in cancer
-
Fusco A, Fedele M. Roles of HMGA proteins in cancer. Nat. Rev. Cancer 7(12), 899-910 (2007).
-
(2007)
Nat. Rev. Cancer
, vol.7
, Issue.12
, pp. 899-910
-
-
Fusco, A.1
Fedele, M.2
-
123
-
-
0029018303
-
Disruption of the architectural factor HMGI-C: DNA-binding at hook motifs fused in lipomas to distinct transcriptional regulatory domains
-
Ashar HR, Fejzo MS, Tkachenko A et al. Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains. Cell 82(1), 57-65 (1995).
-
(1995)
Cell
, vol.82
, Issue.1
, pp. 57-65
-
-
Ashar, H.R.1
Fejzo, M.S.2
Tkachenko, A.3
-
124
-
-
0029088063
-
Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours
-
Schoenmakers EF, Wanschura S, Mols R, Bullerdiek J, Van den Berghe H, Van de Ven WJ. Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours. Nat. Genet. 10(4), 436-444 (1995).
-
(1995)
Nat. Genet.
, vol.10
, Issue.4
, pp. 436-444
-
-
Schoenmakers, E.F.1
Wanschura, S.2
Mols, R.3
Bullerdiek, J.4
Van Den Berghe, H.5
Van De Ven, W.J.6
-
125
-
-
85047700396
-
Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas
-
Fedele M, Battista S, Kenyon L et al. Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas. Oncogene 21(20), 3190-3198 (2002).
-
(2002)
Oncogene
, vol.21
, Issue.20
, pp. 3190-3198
-
-
Fedele, M.1
Battista, S.2
Kenyon, L.3
-
126
-
-
33744808027
-
HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity
-
Fedele M, Visone R, De Martino I et al. HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity. Cancer Cell 9(6), 459-471 (2006).
-
(2006)
Cancer Cell
, vol.9
, Issue.6
, pp. 459-471
-
-
Fedele, M.1
Visone, R.2
De Martino, I.3
-
127
-
-
0034671667
-
The expression of the antiproliferative gene ZAC is lost or highly reduced in nonfunctioning pituitary adenomas
-
Pagotto U, Arzberger T, Theodoropoulou M et al. The expression of the antiproliferative gene ZAC is lost or highly reduced in nonfunctioning pituitary adenomas. Cancer Res. 60(24), 6794-6799 (2000).
-
(2000)
Cancer Res.
, vol.60
, Issue.24
, pp. 6794-6799
-
-
Pagotto, U.1
Arzberger, T.2
Theodoropoulou, M.3
-
128
-
-
17844397712
-
Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors
-
Zhao J, Dahle D, Zhou Y, Zhang X, Klibanski A. Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors. J. Clin. Endocrinol. Metab. 90(4), 2179-2186 (2005).
-
(2005)
J. Clin. Endocrinol. Metab.
, vol.90
, Issue.4
, pp. 2179-2186
-
-
Zhao, J.1
Dahle, D.2
Zhou, Y.3
Zhang, X.4
Klibanski, A.5
-
129
-
-
77149157495
-
Maternally expressed gene 3 (MEG3) noncoding ribonucleic acid: Isoform structure, expression, and functions
-
Zhang X, Rice K, Wang Y et al. Maternally expressed gene 3 (MEG3) noncoding ribonucleic acid: isoform structure, expression, and functions. Endocrinology 151(3), 939-947 (2010).
-
(2010)
Endocrinology
, vol.151
, Issue.3
, pp. 939-947
-
-
Zhang, X.1
Rice, K.2
Wang, Y.3
-
130
-
-
53749086981
-
Selective loss of MEG3 expression and intergenic differentially methylated region hypermethylation in the MEG3/DLK1 locus in human clinically nonfunctioning pituitary adenomas
-
Gejman R, Batista DL, Zhong Y et al. Selective loss of MEG3 expression and intergenic differentially methylated region hypermethylation in the MEG3/DLK1 locus in human clinically nonfunctioning pituitary adenomas. J. Clin. Endocrinol. Metab. 93(10), 4119-4125 (2008).
-
(2008)
J. Clin. Endocrinol. Metab.
, vol.93
, Issue.10
, pp. 4119-4125
-
-
Gejman, R.1
Batista, D.L.2
Zhong, Y.3
-
131
-
-
33745360082
-
Cyclic AMP stimulates MEG3 gene expression in cells through a cAMP-response element (CRE) in the MEG3 proximal promoter region
-
Zhao J, Zhang X, Zhou Y, Ansell PJ, Klibanski A. Cyclic AMP stimulates MEG3 gene expression in cells through a cAMP-response element (CRE) in the MEG3 proximal promoter region. Int. J. Biochem. Cell Biol. 38(10), 1808-1820 (2006).
-
(2006)
Int. J. Biochem. Cell Biol.
, vol.38
, Issue.10
, pp. 1808-1820
-
-
Zhao, J.1
Zhang, X.2
Zhou, Y.3
Ansell, P.J.4
Klibanski, A.5
-
132
-
-
51349089068
-
The emerging role of the Ikaros stem cell factor in the neuroendocrine system
-
Ezzat S, Asa SL. The emerging role of the Ikaros stem cell factor in the neuroendocrine system. J. Mol. Endocrinol. 41(2), 45-51 (2008).
-
(2008)
J. Mol. Endocrinol.
, vol.41
, Issue.2
, pp. 45-51
-
-
Ezzat, S.1
Asa, S.L.2
-
133
-
-
0041924034
-
Ikaros isoforms in human pituitary tumors: Distinct localization, histone acetylation, and activation of the 5 fibroblast growth factor receptor-4 promoter
-
Ezzat S, Yu S, Asa SL. Ikaros isoforms in human pituitary tumors: distinct localization, histone acetylation, and activation of the 5 fibroblast growth factor receptor-4 promoter. Am. J. Pathol. 163(3), 1177-1184 (2003).
-
(2003)
Am. J. Pathol.
, vol.163
, Issue.3
, pp. 1177-1184
-
-
Ezzat, S.1
Yu, S.2
Asa, S.L.3
-
134
-
-
67649446323
-
Pituitary tumours: All silent on the epigenetics front
-
Dudley KJ, Revill K, Clayton RN, Farrell WE. Pituitary tumours: all silent on the epigenetics front. J. Mol. Endocrinol. 42(6), 461-468 (2009).
-
(2009)
J. Mol. Endocrinol.
, vol.42
, Issue.6
, pp. 461-468
-
-
Dudley, K.J.1
Revill, K.2
Clayton, R.N.3
Farrell, W.E.4
-
135
-
-
77956845062
-
The role of germline AIP, MEN1, PRKAR1A,CDKN1B and CDKN2C mutations causing pituitary adenomas in large cohort of children, adolescents and patients with genetic syndromes
-
In press
-
Stratakis CA, Tichomirowa MA, Boikos S et al. The role of germline AIP, MEN1, PRKAR1A,CDKN1B and CDKN2C mutations causing pituitary adenomas in large cohort of children, adolescents and patients with genetic syndromes. Clin. Genet. (2010) (In press).
-
(2010)
Clin. Genet.
-
-
Stratakis, C.A.1
Tichomirowa, M.A.2
Boikos, S.3
-
136
-
-
51649091623
-
Aryl hydrocarbon receptor interacting protein (AIP) gene mutation analysis in children and adolescents with sporadic pituitary adenomas
-
Georgitsi M, De Menis E, Cannavò S et al. Aryl hydrocarbon receptor interacting protein (AIP) gene mutation analysis in children and adolescents with sporadic pituitary adenomas. Clin. Endocrinol. (Oxf.) 69(4), 621-627 (2008).
-
(2008)
Clin. Endocrinol. (Oxf.)
, vol.69
, Issue.4
, pp. 621-627
-
-
Georgitsi, M.1
De Menis, E.2
Cannavò, S.3
|