-
2
-
-
0036831826
-
The pathogenesis of pituitary tumors
-
Asa SL & Ezzat S 2002 The pathogenesis of pituitary tumors. Nature Reviews. Cancer 2 836-849.
-
(2002)
Nature Reviews. Cancer
, vol.2
, pp. 836-849
-
-
Asa, S.L.1
Ezzat, S.2
-
3
-
-
29344458359
-
Genetics and proteomics of pituitary tumors
-
Asa SL & Ezzat S 2005 Genetics and proteomics of pituitary tumors. Endocrine 28 43-47.
-
(2005)
Endocrine
, vol.28
, pp. 43-47
-
-
Asa, S.L.1
Ezzat, S.2
-
4
-
-
1342322685
-
Loss of expression of the growth inhibitory gene GADD45γ, in human pituitary adenomas, is associated with CpG island methylation
-
Bahar A, Bicknell JE, Simpson DJ, Clayton RN & Farrell WE 2004a Loss of expression of the growth inhibitory gene GADD45γ, in human pituitary adenomas, is associated with CpG island methylation. Oncogene 23 936-944.
-
(2004)
Oncogene
, vol.23
, pp. 936-944
-
-
Bahar, A.1
Bicknell, J.E.2
Simpson, D.J.3
Clayton, R.N.4
Farrell, W.E.5
-
5
-
-
3042788949
-
Isolation and characterization of a novel pituitary tumor apoptosis gene
-
Bahar A, Simpson DJ, Cutty SJ, Bicknell JE, Hoban PR, Holley S, Mourtada-Maarabouni M, Williams GT, Clayton RN & Farrell WE 2004b Isolation and characterization of a novel pituitary tumor apoptosis gene. Molecular Endocrinology 18 1827-1839.
-
(2004)
Molecular Endocrinology
, vol.18
, pp. 1827-1839
-
-
Bahar, A.1
Simpson, D.J.2
Cutty, S.J.3
Bicknell, J.E.4
Hoban, P.R.5
Holley, S.6
Mourtada-Maarabouni, M.7
Williams, G.T.8
Clayton, R.N.9
Farrell, W.E.10
-
7
-
-
54249158282
-
Genome wide analysis in a murine Dnmt1 knockdown model identifies epigenetically silenced genes in primary human pituitary tumors
-
Dudley KJ, Revill K, Whitby P, Clayton RN & Farrell WE 2008 Genome wide analysis in a murine Dnmt1 knockdown model identifies epigenetically silenced genes in primary human pituitary tumors. Molecular Cancer Research 6 1567-1574.
-
(2008)
Molecular Cancer Research
, vol.6
, pp. 1567-1574
-
-
Dudley, K.J.1
Revill, K.2
Whitby, P.3
Clayton, R.N.4
Farrell, W.E.5
-
8
-
-
34547792388
-
Epigenetic gene silencing in cancer: The DNA hypermethylome
-
Esteller M 2007 Epigenetic gene silencing in cancer: the DNA hypermethylome. Human Molecular Genetics 16 R50-R59.
-
(2007)
Human Molecular Genetics
, vol.16
-
-
Esteller, M.1
-
9
-
-
51349089068
-
The emerging role of the Ikaros stem cell factor in the neuroendocrine system
-
Ezzat S & Asa SL 2008 The emerging role of the Ikaros stem cell factor in the neuroendocrine system. Journal of Molecular Endocrinology 41 45-51.
-
(2008)
Journal of Molecular Endocrinology
, vol.41
, pp. 45-51
-
-
Ezzat, S.1
Asa, S.L.2
-
10
-
-
0041924034
-
Ikaros isoforms in human pituitary tumors: Distinct localization, histone acetylation, and activation of the 5′ fibroblast growth factor receptor-4 promoter
-
Ezzat S, Yu S & Asa SL 2003 Ikaros isoforms in human pituitary tumors: distinct localization, histone acetylation, and activation of the 5′ fibroblast growth factor receptor-4 promoter. American Journal of Pathology 163 1177-1184.
-
(2003)
American Journal of Pathology
, vol.163
, pp. 1177-1184
-
-
Ezzat, S.1
Yu, S.2
Asa, S.L.3
-
11
-
-
16844373321
-
Ikaros integrates endocrine and immune system development
-
Ezzat S, Mader R, Yu S, Ning T, Poussier P & Asa SL 2005a Ikaros integrates endocrine and immune system development. Journal of Clinical Investigation 115 1021-1029.
-
(2005)
Journal of Clinical Investigation
, vol.115
, pp. 1021-1029
-
-
Ezzat, S.1
Mader, R.2
Yu, S.3
Ning, T.4
Poussier, P.5
Asa, S.L.6
-
12
-
-
15444368750
-
The zinc finger Ikaros transcription factor regulates pituitary growth hormone and prolactin gene expression through distinct effects on chromatin accessibility
-
Ezzat S, Yu S & Asa SL 2005b The zinc finger Ikaros transcription factor regulates pituitary growth hormone and prolactin gene expression through distinct effects on chromatin accessibility. Molecular Endocrinology 19 1004-1011.
-
(2005)
Molecular Endocrinology
, vol.19
, pp. 1004-1011
-
-
Ezzat, S.1
Yu, S.2
Asa, S.L.3
-
13
-
-
33751520959
-
Tumor-derived Ikaros 6 acetylates the Bcl-XL promoter to up-regulate a survival signal in pituitary cells
-
Ezzat S, Zhu X, Loeper S, Fischer S & Asa SL 2006 Tumor-derived Ikaros 6 acetylates the Bcl-XL promoter to up-regulate a survival signal in pituitary cells. Molecular Endocrinology 20 2976-2986.
-
(2006)
Molecular Endocrinology
, vol.20
, pp. 2976-2986
-
-
Ezzat, S.1
Zhu, X.2
Loeper, S.3
Fischer, S.4
Asa, S.L.5
-
14
-
-
22444439588
-
Epigenetic mechanisms of tumorigenesis
-
Farrell WE 2005 Epigenetic mechanisms of tumorigenesis. Hormones Metabolism Research 37 361-368.
-
(2005)
Hormones Metabolism Research
, vol.37
, pp. 361-368
-
-
Farrell, W.E.1
-
15
-
-
33746163546
-
Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma
-
Foltz G, Ryu GY, Yoon JG, Nelson T, Fahey J, Frakes A, Lee H, Field L, Zander K, Sibenaller Z et al. 2006 Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma. Cancer Research 66 6665-6674.
-
(2006)
Cancer Research
, vol.66
, pp. 6665-6674
-
-
Foltz, G.1
Ryu, G.Y.2
Yoon, J.G.3
Nelson, T.4
Fahey, J.5
Frakes, A.6
Lee, H.7
Field, L.8
Zander, K.9
Sibenaller, Z.10
-
16
-
-
0033304571
-
Transfection of an inducible p16/CDKN2A construct mediated reversible growth inhibition and G1 arrest in the AtT20 pituitary tumor cell line
-
Frost SJ, Simpson DJ, Clayton RN & Farrell WE 1999 Transfection of an inducible p16/CDKN2A construct mediated reversible growth inhibition and G1 arrest in the AtT20 pituitary tumor cell line. Molecular Endocrinology 13 1801-1810.
-
(1999)
Molecular Endocrinology
, vol.13
, pp. 1801-1810
-
-
Frost, S.J.1
Simpson, D.J.2
Clayton, R.N.3
Farrell, W.E.4
-
17
-
-
0036613432
-
Role of DNA methylation in the control of cell type specific mapsin expression
-
Futscher BW, Oshiro RJ, Wozniak N, Holtan CL, Hanigan H & Domann FE 2002 Role of DNA methylation in the control of cell type specific mapsin expression. Nature Genetics 31 175-179.
-
(2002)
Nature Genetics
, vol.31
, pp. 175-179
-
-
Futscher, B.W.1
Oshiro, R.J.2
Wozniak, N.3
Holtan, C.L.4
Hanigan, H.5
Domann, F.E.6
-
19
-
-
0031050736
-
Identification and characterisation of differentially methylated regions of genomic DNA by methylation-sensitive arbitrarily primed PCR
-
Gonzalgo ML, Liang G, Spruck CH, Zingg JM, RideoutWH & Jones PA 1997 Identification and characterisation of differentially methylated regions of genomic DNA by methylation-sensitive arbitrarily primed PCR. Cancer Research 57 594-599.
-
(1997)
Cancer Research
, vol.57
, pp. 594-599
-
-
Gonzalgo, M.L.1
Liang, G.2
Spruck, C.H.3
Zingg, J.M.4
RideoutWH5
Jones, P.A.6
-
21
-
-
67649453965
-
Genome-wide identification of DNA-protein interaction using chromatin immunoprecipitation coupled with flow cell sequencing
-
Hoffman BG & Jones SJM 2009 Genome-wide identification of DNA-protein interaction using chromatin immunoprecipitation coupled with flow cell sequencing. Journal of Endocrinology 201 1-13.
-
(2009)
Journal of Endocrinology
, vol.201
, pp. 1-13
-
-
Hoffman, B.G.1
Jones, S.J.M.2
-
22
-
-
0037372003
-
Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
-
Jaenish R & Bird A 2003 Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nature Genetics 33 245-254.
-
(2003)
Nature Genetics
, vol.33
, pp. 245-254
-
-
Jaenish, R.1
Bird, A.2
-
23
-
-
0035839136
-
Translating the histone code
-
Jenuwein T & Allis CD 2001 Translating the histone code. Science 293 1074-1080.
-
(2001)
Science
, vol.293
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
25
-
-
0024404145
-
GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenyl cyclase in human pituitary tumors
-
Landis CA, Masters SB, Spada A, Pace AM, Bourne HR & Vallar L 1989 GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenyl cyclase in human pituitary tumors. Nature 340 692-696.
-
(1989)
Nature
, vol.340
, pp. 692-696
-
-
Landis, C.A.1
Masters, S.B.2
Spada, A.3
Pace, A.M.4
Bourne, H.R.5
Vallar, L.6
-
26
-
-
0036171225
-
Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2′-deoxycytidine
-
Liang G, Gonzales FA, Jones PA, Orntoft TF & Thykjaer T 2002 Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2′-deoxycytidine. Cancer Research 62 961-966.
-
(2002)
Cancer Research
, vol.62
, pp. 961-966
-
-
Liang, G.1
Gonzales, F.A.2
Jones, P.A.3
Orntoft, T.F.4
Thykjaer, T.5
-
27
-
-
33645751058
-
Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state
-
McGarvey KM, Fahrner JA, Greene E, Martens J, Jenuwein T & Baylin SB 2006 Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state. Cancer Research 66 3541-3549.
-
(2006)
Cancer Research
, vol.66
, pp. 3541-3549
-
-
McGarvey, K.M.1
Fahrner, J.A.2
Greene, E.3
Martens, J.4
Jenuwein, T.5
Baylin, S.B.6
-
28
-
-
0347951038
-
Mechanisms of pituitary tumorigenesis: The plastic pituitary
-
Melmed S 2003 Mechanisms of pituitary tumorigenesis: the plastic pituitary. Journal of Clinical Investigation 112 1603-1618.
-
(2003)
Journal of Clinical Investigation
, vol.112
, pp. 1603-1618
-
-
Melmed, S.1
-
29
-
-
0031054097
-
Pituitary carcinoma: A clinicopathologic study of 15 cases
-
Pernicone PJ, Scheithauer B, Sebo TJ, Kovaks KT, Horvath E, Young WF Jr, Lloyd RV, Davis DH, Guthrie BH & Schoene WC 1997 Pituitary carcinoma: a clinicopathologic study of 15 cases. Cancer 79 804-812.
-
(1997)
Cancer
, vol.79
, pp. 804-812
-
-
Pernicone, P.J.1
Scheithauer, B.2
Sebo, T.J.3
Kovaks, K.T.4
Horvath, E.5
Young Jr, W.F.6
Lloyd, R.V.7
Davis, D.H.8
Guthrie, B.H.9
Schoene, W.C.10
-
31
-
-
0033044772
-
Hypermethylation of the p16/CDKN2A/MTSI gene and loss of protein expression is associated with nonfunctional pituitary adenomas but not somatotrophinomas
-
Simpson DJ, Bicknell JE, McNicol AM, Clayton RN & Farrell WE 1999 Hypermethylation of the p16/CDKN2A/MTSI gene and loss of protein expression is associated with nonfunctional pituitary adenomas but not somatotrophinomas. Genes Chromosomes and Cancer 24 328-336.
-
(1999)
Genes Chromosomes and Cancer
, vol.24
, pp. 328-336
-
-
Simpson, D.J.1
Bicknell, J.E.2
McNicol, A.M.3
Clayton, R.N.4
Farrell, W.E.5
-
32
-
-
1842428539
-
Molecular pathology shows p16 methylation in nonadenomatous pituitaries from patients with Cushing's disease
-
Simpson DJ, McNicol AM, Murray DC, Bahar A, Turner HE, Wass JAH, Esiri MM, Clayton RN & Farrell WE 2004 Molecular pathology shows p16 methylation in nonadenomatous pituitaries from patients with Cushing's disease. Clinical Cancer Research 10 1780-1788.
-
(2004)
Clinical Cancer Research
, vol.10
, pp. 1780-1788
-
-
Simpson, D.J.1
McNicol, A.M.2
Murray, D.C.3
Bahar, A.4
Turner, H.E.5
Wass, J.A.H.6
Esiri, M.M.7
Clayton, R.N.8
Farrell, W.E.9
-
33
-
-
0036613250
-
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
-
Suzuki H, Gabrielson E, Chen W, Anbazhagan R, van Engeland M, Weijenberg MP, Herman JG & Baylin SB 2002 A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. Nature Genetics 31 141-149.
-
(2002)
Nature Genetics
, vol.31
, pp. 141-149
-
-
Suzuki, H.1
Gabrielson, E.2
Chen, W.3
Anbazhagan, R.4
van Engeland, M.5
Weijenberg, M.P.6
Herman, J.G.7
Baylin, S.B.8
-
34
-
-
34247625135
-
Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells
-
Tan J, Yang X, Zhuang L, Jiang X, Chen W, Lee PL, Karuturi RK, Tan PB, Liu ET & Yu Q 2007 Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells. Genes and Development 21 1050-1063.
-
(2007)
Genes and Development
, vol.21
, pp. 1050-1063
-
-
Tan, J.1
Yang, X.2
Zhuang, L.3
Jiang, X.4
Chen, W.5
Lee, P.L.6
Karuturi, R.K.7
Tan, P.B.8
Liu, E.T.9
Yu, Q.10
-
35
-
-
0033848849
-
Histone acetylation and an epigenetic code
-
Turner BM 2000 Histone acetylation and an epigenetic code. BioEssays 22 836-845.
-
(2000)
BioEssays
, vol.22
, pp. 836-845
-
-
Turner, B.M.1
-
36
-
-
23044514626
-
Chromosome-wide and promoter-specific analyses identify sites of differential methylation in normal and transformed human cells
-
Weber M, Davies JJ, Wittig D, Oakeley EJ, Haase M, Lam WL & Schubeler D 2005 Chromosome-wide and promoter-specific analyses identify sites of differential methylation in normal and transformed human cells. Nature Genetics 37 853-862.
-
(2005)
Nature Genetics
, vol.37
, pp. 853-862
-
-
Weber, M.1
Davies, J.J.2
Wittig, D.3
Oakeley, E.J.4
Haase, M.5
Lam, W.L.6
Schubeler, D.7
-
37
-
-
0030801289
-
Frequent inactivation of the p16 gene in human pituitary tumours by gene methylation
-
Woloschak M, Yu A & Post KD 1997 Frequent inactivation of the p16 gene in human pituitary tumours by gene methylation. Molecular Carcinogenesis 19 221-224.
-
(1997)
Molecular Carcinogenesis
, vol.19
, pp. 221-224
-
-
Woloschak, M.1
Yu, A.2
Post, K.D.3
-
38
-
-
0036959841
-
Loss of expression of GADD45γ, a growth inhibitory gene, in human pituitary adenomas: Implications for tumorigenesis
-
Zhang X, Sun H, Danila DC, Johnson SR, Zhou Y, Swearingen B & Klibanski A 2002 Loss of expression of GADD45γ, a growth inhibitory gene, in human pituitary adenomas: implications for tumorigenesis. Journal of Clinical Endocrinology and Metabolism 87 1262-1267.
-
(2002)
Journal of Clinical Endocrinology and Metabolism
, vol.87
, pp. 1262-1267
-
-
Zhang, X.1
Sun, H.2
Danila, D.C.3
Johnson, S.R.4
Zhou, Y.5
Swearingen, B.6
Klibanski, A.7
-
39
-
-
0345172377
-
A pituitary derived MEG3 isoform functions as a growth suppressor in tumor cells
-
Zhang X, Zhou Y, Mehta KR, Danila DC, Scolavino S, Johnson SR & Klibanski A 2003 A pituitary derived MEG3 isoform functions as a growth suppressor in tumor cells. Journal of Clinical Endocrinology and Metabolism 88 5119-5126.
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, pp. 5119-5126
-
-
Zhang, X.1
Zhou, Y.2
Mehta, K.R.3
Danila, D.C.4
Scolavino, S.5
Johnson, S.R.6
Klibanski, A.7
-
40
-
-
17844397712
-
Hypermethylation of the promoter region is associated with the loss of Meg3 gene expression in human pituitary tumours
-
Zhao J, Dahle D, Zhou Y, Zhang X & Klibanski A 2005 Hypermethylation of the promoter region is associated with the loss of Meg3 gene expression in human pituitary tumours. Journal of Clinical Endocrinology and Metabolism 90 2179-2186.
-
(2005)
Journal of Clinical Endocrinology and Metabolism
, vol.90
, pp. 2179-2186
-
-
Zhao, J.1
Dahle, D.2
Zhou, Y.3
Zhang, X.4
Klibanski, A.5
-
41
-
-
34250834910
-
Ikaros is regulated through multiple histone modifications and deoxyribonucleic acid methylation in the pituitary
-
Zhu X, Asa SL & Ezzat S 2007a Ikaros is regulated through multiple histone modifications and deoxyribonucleic acid methylation in the pituitary. Molecular Endocrinology 21 2005-2015.
-
(2007)
Molecular Endocrinology
, vol.21
, pp. 2005-2015
-
-
Zhu, X.1
Asa, S.L.2
Ezzat, S.3
-
42
-
-
34250809655
-
Epigenetic silencing through DNA and histone methylation of fibroblast growth factor receptor 2 in neoplastic pituitary cells
-
Zhu X, Lee K, Asa SL & Ezzat S 2007b Epigenetic silencing through DNA and histone methylation of fibroblast growth factor receptor 2 in neoplastic pituitary cells. American Journal of Pathology 170 1618-1628.
-
(2007)
American Journal of Pathology
, vol.170
, pp. 1618-1628
-
-
Zhu, X.1
Lee, K.2
Asa, S.L.3
Ezzat, S.4
-
43
-
-
42249103085
-
Fibroblast growth factor 2 and estrogen control the balance of histone 3 modifications targeting MAGE-A3 in pituitary neoplasia
-
Zhu X, Asa SL & Ezzat S 2008a Fibroblast growth factor 2 and estrogen control the balance of histone 3 modifications targeting MAGE-A3 in pituitary neoplasia. Clinical Cancer Research 14 1984-1996.
-
(2008)
Clinical Cancer Research
, vol.14
, pp. 1984-1996
-
-
Zhu, X.1
Asa, S.L.2
Ezzat, S.3
-
44
-
-
51649114558
-
Deoxyribonucleic acid methyltransferase 3B promotes epigenetic silencing through histone 3 chromatin modifications in pituitary cells
-
Zhu X, Mao X, Hurren R, Schimmer AD, Ezzat S & Asa SL 2008b Deoxyribonucleic acid methyltransferase 3B promotes epigenetic silencing through histone 3 chromatin modifications in pituitary cells. Journal of Clinical Endocrinology and Metabolism 93 3610-3617.
-
(2008)
Journal of Clinical Endocrinology and Metabolism
, vol.93
, pp. 3610-3617
-
-
Zhu, X.1
Mao, X.2
Hurren, R.3
Schimmer, A.D.4
Ezzat, S.5
Asa, S.L.6
|