MicroRNA in human cancer and chronic inflammatory diseases

Frontiers in Bioscience - Scholar

Volumn 2 S, Issue 3, 2010, Pages 1113-1126

  Kanwar, Jagat R ^a   Mahidhara, Ganesh ^a   Kanwar, Rupinder K ^a  

^a DEAKIN UNIVERSITY   (Australia)

Author keywords

Biomarkers; Cancer; Inflammation; MiRNA; Multi drug resistance; Review

Indexed keywords

MICRORNA; RNA;

ANGIOGENESIS; BIOLOGICAL MODEL; DEGENERATIVE DISEASE; DIABETES MELLITUS; DRUG RESISTANCE; FEMALE; GENE EXPRESSION; GENETICS; HUMAN; INFLAMMATION; MALE; METABOLIC DISORDER; METABOLISM; NEOPLASM; NEOVASCULARIZATION (PATHOLOGY); REVIEW; VASCULAR DISEASE; VIRUS INFECTION;

DIABETES MELLITUS; DRUG RESISTANCE, NEOPLASM; FEMALE; GENE EXPRESSION; HUMANS; INFLAMMATION; MALE; METABOLIC DISEASES; MICRORNAS; MODELS, GENETIC; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; NEURODEGENERATIVE DISEASES; RNA, NEOPLASM; VASCULAR DISEASES; VIRUS DISEASES;

EID: 77956644503     PISSN: 19450516     EISSN: 19450524     Source Type: Journal    
DOI: 10.2741/s121     Document Type: Review

References (122)

1. R. C. Lee, R. L. Feinbaum and V. Ambros: The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell, 75 (5), 843-854 (1993) (Pubitemid 24014542)
2. B. J. Reinhart, F. J. Slack, M. Basson, A. E. Pasquinelli, J. C. Bettinger, A. E. Rougvie, H. R. Horvitz and G. Ruvkun: The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature, 403 (6772), 901-906 (2000) (Pubitemid 30130993)
3. B. P. Lewis, C. B. Burge and D. P. Bartel: Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets. Cell, 120 (1), 15-20 (2005) (Pubitemid 40094598)
4. V. Ambros: MicroRNA Pathways in Flies and Worms: Growth, Death, Fat, Stress, and Timing. Cell, 114 (2), 269-269 (2003)
5. V. Ambros: The functions of animal microRNAs. Nature, 431 (7006), 350-355 (2004) (Pubitemid 39265675)
6. G. A. Calin, C. D. Dumitru, M. Shimizu, R. Bichi, S. Zupo, E. Noch, H. Aldler, S. Rattan, M. Keating, K. Rai, L. Rassenti, T. Kipps, M. Negrini, F. Bullrich and C. M. Croce: Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A, 99 (24), 15524-15529 (2002) (Pubitemid 35403967)
7. G. A. Calin and C. M. Croce: MicroRNA signatures in human cancers. Nat Rev Cancer, 6 (11), 857-866 (2006) (Pubitemid 44629897)
8. A. Gaur, D. A. Jewell, Y. Liang, D. Ridzon, J. H. Moore, C. Chen, V. R. Ambros and M. A. Israel: Characterization of MicroRNA Expression Levels and Their Biological Correlates in Human Cancer Cell Lines. Cancer Res, 67 (6), 2456-2468 (2007) (Pubitemid 46548930)
9. P. Sood, A. Krek, M. Zavolan, G. Macino and N. Rajewsky: Cell-type-specific signatures of microRNAs on target mRNA expression. Proc Natl Acad Sci U S A, 103 (8), 2746-2751 (2006)
10. L. P. Lim, N. C. Lau, P. Garrett-Engele, A. Grimson, J. M. Schelter, J. Castle, D. P. Bartel, P. S. Linsley and J. M. Johnson: Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature, 433 (7027), 769-773 (2005) (Pubitemid 40292988)
11. M. Mattie, C. Benz, J. Bowers, K. Sensinger, L. Wong, G. Scott, V. Fedele, D. Ginzinger, R. Getts and C. Haqq: Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies. Mol Cancer, 5 (1), 24 (2006)
12. G. r. György Hutvágner, M. J. Simard, C. C. Mello and P. D. Zamore: Sequence-Specific Inhibition of Small RNA Function. PLoS Biol, 2 (4), e98 (2004)
13. N. R. Jan Krützfeldt, Ravi Braich, Kallanthottathil G. Rajeev, Thomas Tuschl, Muthiah Manoharan & Markus Stoffel: Silencing of microRNAs in vivo with 'antagomirs'. Nature 438, 685-689 (2005)
14. A. Hudder and R. F. Novak: miRNAs: Effectors of Environmental Influences on Gene Expression and Disease. Toxicol. Sci., 103 (2), 228-240 (2008) (Pubitemid 351659596)
15. S. K. Singh, M. P. Bhadra, H. J. Girschick and U. Bhadra: MicroRNAs-micro in size but macro in function. FEBS Journal, 275 (20), 4929-4944 (2008)
16. B. K. Sun and H. Tsao: Small RNAs in development and disease. J Am Acad Der, 59 (5), 725-737 (2008)
17. R. Yi, Y. Qin, I. G. Macara and B. R. Cullen: Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Devp, 17 (24), 3011-3016 (2003) (Pubitemid 38040764)
18. E. Tili, J.-J. Michaille, A. Cimino, S. Costinean, C. D. Dumitru, B. Adair, M. Fabbri, H. Alder, C. G. Liu, G. A. Calin and C. M. Croce: Modulation of miR-155 and miR-125b Levels following Lipopolysaccharide/TNF-alpha Stimulation and Their Possible Roles in Regulating the Response to Endotoxin Shock. J Immunol, 179 (8), 5082-5089 (2007)
19. J. Mattes, A. Collison and P. S. Foster: Emerging role of microRNAs in disease pathogenesis and strategies for therapeutic modulation. Cur Opin Mol Ther, 10 (2), 150-157 (2008) (Pubitemid 351498877)
20. M. Yang and J. Mattes: Discovery, biology and therapeutic potential of RNA interference, microRNA and antagomirs. Pharm Ther, 117 (1), 94-104 (2008) (Pubitemid 350199690)
21. M. P. Perron, V. Boissonneault, L. A. Gobeil, D. L. Quellet and P. Provost: Regulatory RNAs: Future perspectives in diagnosis, prognosis, and individualized therapy. In: Methods Mol Biol. (2007)
22. J. Folkman: Angiogenesis: an organizing principle for drug discovery? Nat Rev Drug Discov, 6 (4), 273-286 (2007) (Pubitemid 46505878)
23. A. Cimmino, G. A. Calin, M. Fabbri, M. V. Iorio, M. Ferracin, M. Shimizu, S. E. Wojcik, R. I. Aqeilan, S. Zupo, M. Dono, L. Rassenti, H. Alder, S. Volinia, C. G. Liu, T. J. Kipps, M. Negrini and C. M. Croce: miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci U S A, 102 (39), 13944-13949 (2005) (Pubitemid 41377683)
24. S. M. Sureban, R. May, S. Ramalingam, D. Subramaniam, G. Natarajan, S. Anant and C. W. Houchen: Selective Blockade of DCAMKL-1 Results in Tumor Growth Arrest by a Let-7a MicroRNA-Dependent Mechanism. Gastroenterology, 137 (2), 649-659.e2 (2009)
25. Y. Akao, Y. Nakagawa and T. Naoe: Let-7 microRNA functions as a potential growth suppressor in human colon cancer cells. Biol Pharm Bull, 29 (5), 903-906 (2006)
26. M. Z. Michael, S. M. O'Connor, N. G. Van Holst Pellekaan, G. P. Young and R. J. James: Reduced Accumulation of Specific MicroRNAs in Colorectal Neoplasia. Canc ResMol Cancer Res, 1 (12), 882-891 (2003) (Pubitemid 37288707)
27. M. V. Iorio, M. Ferracin, C. G. Liu, A. Veronese, R. Spizzo, S. Sabbioni, E. Magri, M. Pedriali, M. Fabbri, M. Campiglio, S. Ménard, J. P. Palazzo, A. Rosenberg, P. Musiani, S. Volinia, I. Nenci, G. A. Calin, P. Querzoli, M. Negrini and C. M. Croce: MicroRNA gene expression deregulation in human breast cancer. Canc Res, 65 (16), 7065-7070 (2005) (Pubitemid 41161233)
28. W. Tam, S. H. Hughes, W. S. Hayward and P. Besmer: Avian bic, a gene isolated from a common retroviral site in avian leukosis virus-induced lymphomas that encodes a noncoding RNA, cooperates with c-myc in lymphomagenesis and erythroleukemogenesis. J Virol, 76 (9), 4275-4286 (2002) (Pubitemid 34309563)
29. A. Ota, H. Tagawa, S. Karnan, S. Tsuzuki, A. Karpas, S. Kira, Y. Yoshida and M. Seto: Identification and Characterization of a Novel Gene, C13orf25, as a Target for 13q31-q32 Amplification in Malignant Lymphoma. Canc Res, 64 (9), 3087-3095 (2004) (Pubitemid 38581408)
30. P. M. Voorhoeve, C. le Sage, M. Schrier, A. J. M. Gillis, H. Stoop, R. Nagel, Y. P. Liu, J. van Duijse, J. Drost, A. Griekspoor, E. Zlotorynski, N. Yabuta, G. De Vita, H. Nojima, L. H. J. Looijenga and R. Agami: A Genetic Screen Implicates miRNA-372 and miRNA-373 As Oncogenes in Testicular Germ Cell Tumors. Cell, 124 (6), 1169-1181 (2006)
31. J. A. Chan, A. M. Krichevsky and K. S. Kosik: MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Canc Res, 65 (14), 6029-6033 (2005) (Pubitemid 40994386)
32. J. Takamizawa, H. Konishi, K. Yanagisawa, S. Tomida, H. Osada, H. Endoh, T. Harano, Y. Yatabe, M. Nagino, Y. Nimura, T. Mitsudomi and T. Takahashi: Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Canc Res, 64 (11), 3753-3756 (2004) (Pubitemid 38697282)
33. M. V. Iorio, P. Casalini, E. Tagliabue, S. Ménard and C. M. Croce: MicroRNA profiling as a tool to understand prognosis, therapy response and resistance in breast cancer. Eur J Canc, 44 (18), 2753-2759 (2008)
34. J. Lu, G. Getz, E. A. Miska, E. Alvarez-Saavedra, J. Lamb, D. Peck, A. Sweet-Cordero, B. L. Ebert, R. H. Mak, A. A. Ferrando, J. R. Downing, T. Jacks, H. R. Horvitz and T. R. Golub: MicroRNA expression profiles classify human cancers. Nature, 435 (7043), 834-838 (2005) (Pubitemid 40839735)
35. N. Yanaihara, N. Caplen, E. Bowman, M. Seike, K. Kumamoto, M. Yi, R. M. Stephens, A. Okamoto, J. Yokota, T. Tanaka, G. A. Calin, C. G. Liu, C. M. Croce and C. C. Harris: Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell, 9 (3), 189-198 (2006) (Pubitemid 43357945)
36. M. P. Hunter, N. Ismail, X. Zhang, B. D. Aguda, E. J. Lee, L. Yu, T. Xiao, J. Schafer, M. L. T. Lee, T. D. Schmittgen, S. P. Nana-Sinkam, D. Jarjoura and C. B. Marsh: Detection of microRNA expression in human peripheral blood microvesicles. PLoS One, 3 (11) (2008)
37. H. Valadi, K. Ekström, A. Bossios, M. Sjöstrand, J. J. Lee and J. O. Lötvall: Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol, 9 (6), 654-659 (2007) (Pubitemid 47214727)
38. D. D. Taylor and C. Gercel-Taylor: MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecol Oncol, 110 (1), 13-21 (2008) (Pubitemid 351853251)
39. G. Rabinowits, C. Gerçel-Taylor, J. M. Day, D. D. Taylor and G. H. Kloecker: Exosomal microRNA: A diagnostic marker for lung cancer. Clin Lung Canc, 10 (1), 42-46 (2009)
40. W. Zhu, W. Qin, U. Atasoy and E. Sauter: Circulating microRNAs in breast cancer and healthy subjects. BMC Res notes, 2 (1), 89 (2009)
41. R. Rosell, J. Wei and M. Taron: Circulating microRNA signatures of tumor-derived exosomes for early diagnosis of non-small-cell lung cancer. Clin Lung Canc, 10 (1), 8-9 (2009)
42. P. Zimmet, K. G. M. M. Alberti and J. Shaw: Global and societal implications of the diabetes epidemic. Nature, 414 (6865), 782-787 (2001) (Pubitemid 34000780)
43. K. I. Rother: Diabetes treatment - Bridging the divide. NEJM, 356 (15), 1499-1501 (2007) (Pubitemid 46588414)
44. M. J. Weigensberg and M. I. Goran: Type 2 diabetes in children and adolescents. The Lancet, 373 (9677), 1743-1744 (2009)
45. M. N. Poy, L. Eliasson, J. Krutzfeldt, S. Kuwajima, X. Ma, P. E. MacDonald, S. Pfeffer, T. Tuschl, N. Rajewsky, P. Rorsman and M. Stoffel: A pancreatic islet-specific microRNA regulates insulin secretion. Nature, 432 (7014), 226-230 (2004) (Pubitemid 39545853)
46. W. P. Kloosterman, A. K. Lagendijk, R. F. Ketting, J. D. Moulton and R. H. A. Plasterk: Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development. PLoS Biol, 5 (8), 1738-1749 (2007) (Pubitemid 47328277)
47. 2 cells reveals a role for miR-30d in insulin transcription. RNA, 15 (2), 287-293 (2009)
48. 2-cell lines. JBC, 282 (27), 19575-19588 (2007) (Pubitemid 47100119)
49. 2-Cells in vivo. Diabetes, 51 (8), 2546-2551 (2002) (Pubitemid 34827405)
50. 2) Controls Multiple Genes Implicated in Metabolism-Secretion Coupling of Glucose-induced Insulin Release. JBC, 277 (20), 17564-17570 (2002) (Pubitemid 34967558)
51. K. A. Lantz, M. Z. Vatamaniuk, J. E. Brestelli, J. R. Friedman, F. M. Matschinsky and K. H. Kaestner: Foxa2 regulates multiple pathways of insulin secretion. J Clin Inv, 114 (4), 512-520 (2004) (Pubitemid 39572101)
52. Y. Sun, S. Koo, N. White, E. Peralta, C. Esau, N. M. Dean and R. J. Perera: Development of a micro-array to detect human and mouse microRNAs and characterization of expression in human organs. NAR, 32 (22) (2004)
53. C. Esau, X. Kang, E. Peralta, E. Hanson, E. G. Marcusson, L. V. Ravichandran, Y. Sun, S. Koo, R. J. Perera, R. Jain, N. M. Dean, S. M. Freier, C. F. Bennett, B. Lollo and R. Griffey: MicroRNA-143 regulates adipocyte differentiation. JBC, 279 (50), 52361-52365 (2004) (Pubitemid 39656612)
54. J. Bilen, N. Liu and N. M. Bonini: A new role for microRNA pathways: Modulation of degeneration induced by pathogenic human disease proteins. Cell Cycle, 5 (24), 2835-2838 (2006) (Pubitemid 44953931)
55. S. Przedborski, M. Vila and V. Jackson-Lewis: Series Introduction: Neurodegeneration: What is it and where are we? The J Clin Inv, 111 (1), 3-10 (2003) (Pubitemid 36134839)
56. J. R. Kanwar: Anti-inflammatory immunotherapy for multiple sclerosis/experimental autoimmune encephalomyelitis (EAE) disease. Curr Med Chem, 12 (25), 2947-62 (2005) (Pubitemid 41672485)
57. A. Schaefer, D. O'Carroll, L. T. Chan, D. Hillman, M. Sugimori, R. Llinas and P. Greengard: Cerebellar neurodegeneration in the absence of microRNAs. J Expt Med, 204 (7), 1553-1558 (2007) (Pubitemid 47048023)
58. J. Kim, K. Inoue, J. Ishii, W. B. Vanti, S. V. Voronov, E. Murchison, G. Hannon and A. Abeliovich: A microRNA feedback circuit in midbrain dopamine neurons. Science, 317 (5842), 1220-1224 (2007)
59. W.-X. Wang, B. W. Rajeev, A. J. Stromberg, N. Ren, G. Tang, Q. Huang, I. Rigoutsos and P. T. Nelson: The Expression of MicroRNA miR-107 Decreases Early in Alzheimer's Disease and May Accelerate Disease Progression through Regulation of {beta}-Site Amyloid Precursor Protein-Cleaving Enzyme 1. J. Neurosci., 28 (5), 1213-1223 (2008) (Pubitemid 351186356)
60. 2- secretase expression. Proceedings of the National Academy of Sciences of the United States of America, 105 (17), 6415-6420 (2008) (Pubitemid 351758360)
61. W. J. Lukiw: Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus. NeuroReport, 18 (3), 297-300 (2007)
62. W. J. Lukiw and A. I. Pogue: Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells. J Inorg Biochem, 101 (9), 1265-1269 (2007) (Pubitemid 47313522)
63. * regulates REST and CoREST and is downregulated in Huntington's disease. J Neurosci, 28 (53), 14341-14346 (2008)
64. Y. Lee, R. C. Samaco, J. R. Gatchel, C. Thaller, H. T. Orr and H. Y. Zoghbi: miR-19, miR-101 and miR-130 co-regulate ATXN1 levels to potentially modulate SCA1 pathogenesis. Nat Neurosci, 11 (10), 1137-1139 (2008)
65. R. Saba, C. D. Goodman, R. L. C. H. Huzarewich, C. Robertson and S. A. Booth: A miRNA signature of prion induced neurodegeneration. PLoS One, 3 (11) (2008)
66. J. R. Kanwar, G. Mahidhara and R. K. Kanwar: Recent Advances in Nanoneurology for Drug Delivery to the Brain. Cur NanoSci, 5 (4), 1573-4137 (2009)
67. N. M. Pandya, N. S. Dhalla and D. D. Santani: Angiogenesis - a new target for future therapy. Vasc Pharmacol, 44 (5), 265-274 (2006)
68. 2 generation. Clin Expt Immunol, 147 (2), 227-235 (2007) (Pubitemid 46095999)
69. J. R. Kanwar, R. K. Kanwar, H. Burrow and S. Baratchi: Recent Advances on the Roles of NO in Cancer and Chronic Inflammatory Disorders. Curr Med Chem, 16, 2373-2394 (2009)
70. C. L. Van Hove, T. Maes, G. F. Joos and K. G. Tournoy: Chronic inflammation in asthma: A contest of persistence vs resolution. Allergy: Eur J aller Clin Imm, 63 (9), 1095-1109 (2008)
71. R. K. Kanwar, J. R. Kanwar, D. Wang, D. J. Ormrod and G. W. Krissansen: Temporal expression of heat shock proteins 60 and 70 at lesion-prone sites during atherogenesis in apoE-deficient mice. ATVB, 21 (12), 1991-1997 (2001) (Pubitemid 34219752)
72. J. R. Kanwar, R. K. Kanwar and G. W. Krissansen: Simultaneous neuroprotection and blockade of inflammation reverses autoimmune encephalomyelitis. Brain, 127 (6), 1313-1331 (2004) (Pubitemid 38745510)
73. J. R. Kanwar, R. K. Kanwar, D. Wang and G. W. Krissansen. Prevention of a chronic progressive form of experimental autoimmune encephalomyelitis by an antibody against mucosal addressin cell adhesion molecule-1, given early in the course of disease progression. Immunol Cell Biol, 78(6):641-5 (2000)
74. J. E. Fish, M. M. Santoro, S. U. Morton, S. Yu, R. F. Yeh, J. D. Wythe, K. N. Ivey, B. G. Bruneau, D. Y. R. Stainier and D. Srivastava: miR-126 Regulates Angiogenic Signaling and Vascular Integrity. Devp Cell, 15 (2), 272-284 (2008)
75. S. Wang, A. B. Aurora, B. A. Johnson, X. Qi, J. McAnally, J. A. Hill, J. A. Richardson, R. Bassel-Duby and E. N. Olson: The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis. Devp Cell, 15 (2), 261-271 (2008)
76. T. A. Harris, M. Yamakuchi, M. Ferlito, J. T. Mendell and C. J. Lowenstein: MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. Proc Natl Acad Sci U S A, 105 (5), 1516-1521 (2008) (Pubitemid 351346546)
77. M. M. Martin, E. J. Lee, J. A. Buckenberger, T. D. Schmittgen and T. S. Elton: MicroRNA-155 regulates human angiotensin II type 1 receptor expression in fibroblast. JBC, 281 (27), 18277-18284 (2006) (Pubitemid 44035484)
78. M. M. Martin, J. A. Buckenberger, J. Jiang, G. E. Malana, G. J. Nuovo, M. Chotani, D. S. Feldman, T. D. Schmittgen and T. S. Elton: The Human Angiotensin II Type 1 Receptor +1166 A/C Polymorphism Attenuates MicroRNA-155 Binding. JBC, 282 (33), 24262-24269 (2007) (Pubitemid 47328062)
79. R. M. O'Connell, K. D. Taganov, M. P. Boldin, G. Cheng and D. Baltimore: MicroRNA-155 is induced during the macrophage inflammatory response. Proc Natl Acad Sci U S A, 104 (5), 1604-1609 (2007) (Pubitemid 46214637)
80. E. Tili, J. J. Michaille, A. Cimino, S. Costinean, C. D. Dumitru, B. Adair, M. Fabbri, H. Alder, G. L. Chang, G. A. Calin and C. M. Croce: Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNFalpha stimulation and their possible roles in regulating the response to endotoxin shock. J Immunol, 179 (8), 5082-5089 (2007)
81. R. M. O'Connell, D. S. Rao, A. A. Chaudhuri, M. P. Boldin, K. D. Taganov, J. Nicoll, R. L. Paquette and D. Baltimore: Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder. J. Exp. Med., 205 (3), 585-594 (2008) (Pubitemid 351439306)
82. A. Rodriguez, E. Vigorito, S. Clare, M. V. Warren, P. Couttet, D. R. Soond, S. Van Dongen, R. J. Grocock, P. P. Das, E. A. Miska, D. Vetrie, K. Okkenhaug, A. J. Enright, G. Dougan, M. Turner and A. Bradley: Requirement of bic/microRNA-155 for normal immune function. Science, 316 (5824), 608-611 (2007) (Pubitemid 46683148)
83. E. Vigorito, K. L. Perks, C. Abreu-Goodger, S. Bunting, Z. Xiang, S. Kohlhaas, P. P. Das, E. A. Miska, A. Rodriguez, A. Bradley, K. G. C. Smith, C. Rada, A. J. Enright, K. M. Toellner, I. C. M. MacLennan and M. Turner: microRNA-155 Regulates the Generation of Immunoglobulin Class-Switched Plasma Cells. Immunity, 27 (6), 847-859 (2007) (Pubitemid 350258623)
84. B. Zhou, S. Wang, C. Mayr, D. P. Bartel and H. F. Lodish: miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely. Proc Natl Acad Sci U S A, 104 (17), 7080-7085 (2007) (Pubitemid 47186012)
85. A. Rosa, M. Ballarino, A. Sorrentino, O. Sthandier, F. G. De Angelis, M. Marchioni, B. Masella, A. Guarini, A. Fatica, C. Peschle and I. Bozzoni: The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation. Proc Natl Acad Sci U S A, 104 (50), 19849-19854 (2007)
86. L. Fontana, E. Pelosi, P. Greco, S. Racanicchi, U. Testa, F. Liuzzi, C. M. Croce, E. Brunetti, F. Grignani and C. Peschle: MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation. Nat Cell Biol, 9 (7), 775-787 (2007) (Pubitemid 47019464)
87. J. B. Johnnidis, M. H. Harris, R. T. Wheeler, S. Stehling-Sun, M. H. Lam, O. Kirak, T. R. Brummelkamp, M. D. Fleming and F. D. Camargo: Regulation of progenitor cell proliferation and granulocyte function by microRNA-223. Nature, 451 (7182), 1125-1129 (2008) (Pubitemid 351317447)
88. T. X. Lu, A. Munitz and M. E. Rothenberg: MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression. J Immunol (Baltimore, Md.: 1950), 182 (8), 4994-5002 (2009)
89. T. Ruggiero, M. Trabucchi, F. De Santa, S. Zupo, B. D. Harfe, M. T. McManus, M. G. Rosenfeld, P. Briata and R. Gherzi: LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages. FASEB Journal, 23 (9), 2898-2908 (2009)
90. F. Bazzoni, M. Rossato, M. Fabbri, D. Gaudiosi, M. Mirolo, L. Mori, N. Tamassia, A. Mantovani, M. A. Cassatella and M. Locati: Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals. Proc Natl Acad Sci U S A, 106 (13), 5282-5287 (2009)
91. S. K. Singh: RNA interference and its therapeutic potential against HIV infection. Exp Opin Biol Ther, 8 (4), 449-461 (2008) (Pubitemid 351570409)
92. J. E. Cameron, Q. Yin, C. Fewell, M. Lacey, J. McBride, X. Wang, Z. Lin, B. C. Schaefer and E. K. Flemington: Epstein-Barr virus latent membrane protein 1 induces cellular microRNA miR-146a, a modulator of lymphocyte signaling pathways. J Virol, 82 (4), 1946-1958 (2008) (Pubitemid 351206940)
93. N. Motsch, T. Pfuhl, J. Mrazek, S. Barth and F. A. Grässer: Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) induces the expression of the cellular microRNA miR-146a. RNA Biology, 4 (3), 131-137 (2007) (Pubitemid 351237914)
94. G. Gatto, A. Rossi, D. Rossi, S. Kroening, S. Bonatti and M. Mallardo: Epstein-Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-kappaB pathway. NAR, 36 (20), 6608-6619 (2008)
95. J. Huang, F. Wang, E. Argyris, K. Chen, Z. Liang, H. Tian, W. Huang, K. Squires, G. Verlinghieri and H. Zhang: Cellular microRNAs contribute to HIV-1 latency in resting primary CD4 + T lymphocytes. Nat Med, 13 (10), 1241-1247 (2007) (Pubitemid 47530631)
96. Z. Klase, R. Winograd, J. Davis, L. Carpio, R. Hildreth, M. Heydarian, S. Fu, T. McCaffrey, E. Meiri, M. Ayash-Rashkovsky, S. Gilad, Z. Bentwich and F. Kashanchi: HIV-1 TAR miRNA protects against apoptosis by altering cellular gene expression. Retrovirology, 6 (2009)
97. W. B. Jin, F. L. Wu, D. Kong and A. G. Guo: HBV-encoded microRNA candidate and its target. Comp Biol Chem, 31 (2), 124-126 (2007) (Pubitemid 46528858)
98. Y. Liu, J. J. Zhao, C. M. Wang, M. Y. Li, P. Han, L. Wang, Y. Q. Cheng, F. Zoulim, X. Ma and D. P. Xu: Altered expression profiles of microRNAs in a stable hepatitis B virus-expressing cell line. Chin Med Jour, 122 (1), 10-14 (2009)
99. M. A. Samols, R. L. Skalsky, A. M. Maldonado, A. Riva, M. C. Lopez, H. V. Baker and R. Renne: Identification of cellular genes targeted by KSHV-encoded microRNAs. PLoS Pathogens, 3 (5), 0611-0618 (2007) (Pubitemid 46827946)
100. X. Wang, H. K. Wang, J. P. McCoy, N. S. Banerjee, J. S. Rader, T. R. Broker, C. Meyers, L. T. Chow and Z. M. Zheng: Oncogenic HPV infection interrupts the expression of tumor-suppressive miR-34a through viral oncoprotein E6. RNA, 15 (4), 637-647 (2009)
101. S. Pfeffer and T. F. Baumert: Unravelling the importance of microRNAs during hepatitis C virus infection in the human liver. Journal of Hepatology, 51 (3), 606-609 (2009)
102. M. Sarasin-Filipowicz, J. Krol, I. Markiewicz, M. H. Heim and W. Filipowicz: Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy. Nat Med, 15 (1), 31-33 (2009)
103. L. Xia, D. Zhang, R. Du, Y. Pan, L. Zhao, S. Sun, L. Hong, J. Liu and D. Fan: miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. International Journal of Cancer, 123 (2), 372-379 (2008) (Pubitemid 351842022)
104. I. B. Roninson: The role of the MDR1 (p-glycoprotein) gene in multidrug resistance in vitro and in vivo. Biochem Pharm, 43 (1), 95-102 (1992)
105. K. Zhang, P. Mack and K. P. Wong: Glutathione-related mechanisms in cellular resistance to anticancer drugs (Review). Int J Onc, 12 (4), 871-882 (1998) (Pubitemid 28133581)
106. R. W. Johnstone, A. A. Ruefli and S. W. Lowe: Apoptosis: A link between cancer genetics and chemotherapy. Cell, 108 (2), 153-164 (2002) (Pubitemid 34161136)
107. J. R. Kanwar, W. P. Shen, R. K. Kanwar, R. W. Berg and G. W. Krissansen: Effects of survivin antagonists on growth of established tumors and B7-1 immunogene therapy. JNCI, 93 (20), 1541-1552 (2001) (Pubitemid 32998483)
108. R. K. Kanwar, C. H. A. Cheung., J.Y. Chang. and J. R. Kanwar: Recent advances in Anti survivin Treatments for cancer. Curr Med Chem, 17 (2010)
109. C. H. A. Cheung, H. H. Chen, C. C. Kuo, C. Y. Chang, M. S. Coumar, H. P. Hsieh and J. Y. Chang: Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers. Mol Cancer, 8:43 (2009)
110. P. E. Blower, Ji-H. Chung, J. S. Verducci, S. Lin, J-K. Park, Z. Dai, C-G. Liu, T. D. Schmittgen, W. C. Reinhold, C. M. Croce, J. N. Weinstein and W. Sadee. MicroRNAs modulate the chemosensitivity of tumor cells. Mol Cancer Ther, 7 (1): OF1-9 (2008)
111. A. Esquela-Kerscher and F. J. Slack: Oncomirs-MicroRNAs with a role in cancer. Nat Rev Canc, 6 (4), 259-269 (2006)
112. H. W. Hwang and J. T. Mendell: MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br J Cancer, 94 (6), 776-780 (2006)
113. M. Garofalo, G. Condorelli and C. M. Croce. MicroRNAs in diseases and drug response. Cur Opin Pharm, 8 (5):661-667 (2008)
114. P. E. Blower, J. S. Verducci, S. Lin, J. Zhou, J.-H. Chung, Z. Dai, C.-G. Liu, W. Reinhold, P. L. Lorenzi, E. P. Kaldjian, C. M. Croce, J. N. Weinstein and W. Sadee: MicroRNA expression profiles for the NCI-60 cancer cell panel. Mol Cancer Ther, 6 (5), 1483-1491 (2007) (Pubitemid 46954015)
115. T. Zheng, J. Wang, X. Chen and L. Liu. Role of microRNA in anticancer drug resistance. International Journal of Cancer, 126: 2-10 (2010)
116. T. E. Miller, K. Ghoshal, B. Ramaswamy, S. Roy, J. Datta, C. L. Shapiro, S. Jacob and S. Majumder. MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27 (Kip1). JBC, 283 (44): 29897-29903 (2008)
117. M. L. Si, S. Zhu, H W.u., Z Lu, F Wu, Y. Y. Mo. miR-21-mediated tumor growth. Oncogene 2007; 26: 2799-803. (Pubitemid 46663837)
118. C.J. Murray, A. D Lopez. Alternative projections of mortality and disability by cause 1990-2020: global burden of disease study. Lancet, 349:1498-504 (1997) (Pubitemid 27216360)
119. F. Meng, R. Henson, M. Lang, H. Wehbe, S. Maheshwari, J. T. Mendell, J. Jiang, T. D. Schmittgen and T. Patel: Involvement of Human Micro-RNA in Growth and Response to Chemotherapy in Human Cholangiocarcinoma Cell Lines. Gastroenterology, 130 (7), 2113-2129 (2006) (Pubitemid 43816961)
120. L. Rossi, E. Bonmassar and I. Faraoni: Modification of miR gene expression pattern in human colon cancer cells following exposure to 5-fluorouracil in vitro. Pharmacol Res, 56 (3), 248-253 (2007) (Pubitemid 47321208)
121. A. Sorrentinoa, C-G. Liuc, A. Addarioa, C. Peschlea, G. Scambia and C. Ferlini. Role of microRNAs in drug-resistant ovarian cancer cells. Gynecol Oncol, 111 (3):478-486 (2008)
122. M. Kozak: Faulty old ideas about translational regulation paved the way for current confusion about how microRNAs function. Gene, 423 (2), 108-115 (2008)