Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy

Nature Medicine

Volumn 15, Issue 1, 2009, Pages 31-33

  Sarasin Filipowicz, Magdalena ^a,b   Krol, Jacek ^c   Markiewicz, Ilona ^c   Heim, Markus H ^a,b   Filipowicz, Witold ^c  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

^c FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; PEGINTERFERON ALPHA;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HEPATITIS C; HUMAN; HUMAN TISSUE; LIVER BIOPSY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TREATMENT RESPONSE; VIRUS LOAD; VIRUS REPLICATION;

ANTIVIRAL AGENTS; BIOMARKERS, PHARMACOLOGICAL; CELLS, CULTURED; DOWN-REGULATION; DRUG RESISTANCE, VIRAL; HEPATITIS C; HUMANS; INTERFERON-ALPHA; LIVER; MICRORNAS; TREATMENT FAILURE; VIRAL LOAD;

HEPATITIS C VIRUS;

EID: 58149333128     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.1902     Document Type: Article

References (11)

1. Jopling, C.L., Yi, M., Lancaster, A.M., Lemon, S.M. & Sarnow, P. Science 309, 1577-1581 (2005).
2. Randall, G. et al. Proc. Natl. Acad. Sci. USA 104, 12884-12889 (2007).
3. Manns, M.P. et al. Lancet 358, 958-965 (2001).
4. Fried, M.W. et al. N. Engl. J. Med. 347, 975-982 (2002).
5. Pedersen, I.M. et al. Nature 449, 919-922 (2007).
6. Sarasin-Filipowicz, M. et al. Proc. Natl. Acad. Sci. USA 105, 7034-7039 (2008).
7. Brown, B.D. et al. Nat. Biotechnol. 25, 1457-1467 (2007).
8. Griffiths-Jones, S., Saini, H.K., van Dongen, S. & Enright, A.J. Nucleic Acids Res. 36, D154-D158 (2008).
9. Elmen, J. et al. Nature 452, 896-899 (2008).
10. Chen, L. et al. Gastroenterology 128, 1437-1444 (2005).
11. Asselah, T. et al. Gut 57, 516-524 (2008).