Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers

Molecular Cancer

Volumn 8, Issue , 2009, Pages

  Cheung, Chun Hei Antonio ^a   Chen, Huang Hui ^a   Kuo, Ching Chuan ^a   Chang, Chi Yen ^a   Coumar, Mohane S ^a   Hsieh, Hsing Pang ^a   Chang, Jang Yang ^a,b  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

6 METHOXY 3 ( 3', 4', 5' TRIMETHOXY BENZOYL) 1H INDOLE; APOPTOSIS INDUCING FACTOR; BPR 0L 075; CASPASE 3; CASPASE 7; COLCHICINE; COMBRETASTATIN A4; SMALL INTERFERING RNA; SURVIVIN; UNCLASSIFIED DRUG; 6 METHOXY 3 (3',4',5' TRIMETHOXYBENZOYL) 1H INDOLE; 6-METHOXY-3-(3',4',5'-TRIMETHOXYBENZOYL)-1H-INDOLE; ANTINEOPLASTIC AGENT; BIRC5 PROTEIN, HUMAN; CASP7 PROTEIN, HUMAN; INDOLE DERIVATIVE; MICROTUBULE ASSOCIATED PROTEIN; TUBULIN;

ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CELL NUCLEUS; CELL STRAIN KB; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DOWN REGULATION; DRUG RESISTANCE; DRUG SENSITIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE OVEREXPRESSION; GENE TARGETING; GENE TRANSLOCATION; HUMAN; HUMAN CELL; IC 50; MICROTUBULE; WESTERN BLOTTING; APOPTOSIS; DRUG EFFECT; GENETICS; METABOLISM; TUMOR CELL LINE;

VINCA;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASE 7; CELL LINE, TUMOR; COLCHICINE; DOWN-REGULATION; HUMANS; INDOLES; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; RNA, SMALL INTERFERING; TRANSLOCATION, GENETIC; TUBULIN;

EID: 68249142910     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-8-43     Document Type: Article

References (49)

1. Sawada T Cabral F Expression and function of beta-tubulin isotypes in Chinese hamster ovary cells J Biol Chem 1989, 264:3013-3020 2644275
2. Wade RH Hyman AA Microtubule structure and dynamics Curr Opin Cell Biol 1997, 9:12-17 10.1016/S0955-0674(97)80146-9 9013674
3. Kiselyov A Balakin KV Tkachenko SE Savchuk N Ivachtchenko AV Recent progress in discovery and development of antimitotic agents Anticancer Agents Med Chem 2007, 7:189-208 10.2174/187152007780058650 17348827
4. Shi Q Chen K Morris-Natschke SL Lee KH Recent progress in the development of tubulin inhibitors as antimitotic antitumor agents Curr Pharm Des 1998, 4:219-248 10197041
5. Arrieta O Rodriguez-Diaz JL Rosas-Camargo V Morales-Espinosa D Ponce de Leon S Kershenobich D Leon-Rodriguez E Colchicine delays the development of hepatocellular carcinoma in patients with hepatitis virus-related liver cirrhosis Cancer 2006, 107:1852-1858 10.1002/cncr.22198 16967451
6. Tanaka Y Fujiwara K Tanaka H Maehata K Kohno I Paclitaxel inhibits expression of heat shock protein 27 in ovarian and uterine cancer cells Int J Gynecol Cancer 2004, 14:616-620 10.1111/j.1048-891X.2004.14409.x 15304155
7. Raitanen M Rantanen V Kulmala J Pulkkinen J Klemi P Grenman S Grenman R Paclitaxel combined with fractionated radiation in vitro: A study with vulvar squamous cell carcinoma cell lines Int J Cancer 2002, 97:853-857 10.1002/ijc.10133 11857367
8. Dumontet C Sikic BI Mechanisms of action of and resistance to antitubulin agents: Microtubule dynamics, drug transport, and cell death J Clin Oncol 1999, 17:1061-1070 10071301
9. Cornelissen JJ Sonneveld P Schoester M Raaijmakers HG Nieuwenhuis HK Dekker AW Lokhorst HM MDR-1 expression and response to vincristine, doxorubicin, and dexamethasone chemotherapy in multiple myeloma refractory to alkylating agents J Clin Oncol 1994, 12:115-119 7903690
10. Deng L Tatebe S Lin-Lee YC Ishikawa T Kuo MT MDR and MRP gene families as cellular determinant factors for resistance to clinical anticancer agents Cancer Treat Res 2002, 112:49-66 12481711
11. Liou JP Chang YL Kuo FM Chang CW Tseng HY Wang CC Yang YN Chang JY Lee SJ Hsieh HP Concise synthesis and structure-activity relationships of combretastatin A-4 analogues, 1-aroylindoles and 3-aroylindoles, as novel classes of potent antitubulin agents J Med Chem 2004, 47:4247-4257 10.1021/jm049802l 15293996
12. Kuo CC Hsieh HP Pan WY Chen CP Liou JP Lee SJ Chang YL Chen LT Chen CT Chang JY BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo Cancer Res 2004, 64:4621-4628 10.1158/0008-5472.CAN-03-3474 15231674
13. Pennati M Folini M Zaffaroni N Targeting survivin in cancer therapy: fulfilled promises and open questions Carcinogenesis 2007, 28:1133-1139 10.1093/carcin/bgm047 17341657
14. Kojima H Iida M Yaguchi Y Suzuki R Hayashi N Moriyama H Manome Y Enhancement of Cisplatin sensitivity in squamous cell carcinoma of the head and neck transfected with a survivin antisense gene Arch Otolaryngol Head Neck Surg 2006, 132:682-685 10.1001/archotol.132.6.682 16785416
15. Zhang M Mukherjee N Bermudez RS Latham DE Delaney MA Zietman AL Shipley WU Chakravarti A Adenovirus-mediated inhibition of survivin expression sensitizes human prostate cancer cells to paclitaxel in vitro and in vivo Prostate 2005, 64:293-302 10.1002/pros.20263 15754318
16. Shin S Sung BJ Cho YS Kim HJ Ha NC Hwang JI Chung CW Jung YK Oh BH An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7 Biochemistry 2001, 40:1117-1123 10.1021/bi001603q 11170436
17. Tamm I Wang Y Sausville E Scudiero DA Vigna N Oltersdorf T Reed JC IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs Cancer Res 1998, 58:5315-5320 9850056
18. Dohi T Beltrami E Wall NR Plescia J Altieri DC Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis J Clin Invest 2004, 114:1117-1127 522254 15489959
19. Uren AG Wong L Pakusch M Fowler KJ Burrows FJ Vaux DL Choo KH Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype Current Biology 2000, 10:1319-1328 10.1016/S0960-9822(00)00769-7 11084331
20. Rosa J Canovas P Islam A Altieri DC Doxsey SJ Survivin modulates microtubule dynamics and nucleation throughout the cell cycle Mol Biol Cell 2006, 17:1483-1493 1382334 16407408 10.1091/mbc.E05-08-0723
21. Fortugno P Wall NR Giodini A O'Connor DS Plescia J Padgett KM Tognin S Marchisio PC Altieri DC Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function J Cell Sci 2002, 115:575-585 11861764
22. Zaffaroni N Daidone MG Survivin expression and resistance to anticancer treatments: Perspectives for new therapeutic interventions Drug Resist Updat 2002, 5:65-72 10.1016/S1368-7646(02)00049-3 12135582
23. Carvalho A Carmena M Sambade C Earnshaw WC Wheatley SP Survivin is required for stable checkpoint activation in taxol-treated HeLa cells J Cell Sci 2003, 116:2987-2998 10.1242/jcs.00612 12783991
24. Shi W Bastianutto C Li A Perez-Ordonez B Ng R Chow KY Zhang W Jurisica I Lo KW Bayley A Kim J O'Sullivan B Siu L Chen E Liu FF Multiple dysregulated pathways in nasopharyngeal carcinoma revealed by gene expression profiling Int J Cancer 2006, 119:2467-2475 10.1002/ijc.22107 16858677
25. Mirza A McGuirk M Hockenberry TN Wu Q Ashar H Black S Wen SF Wang L Kirschmeier P Bishop WR Nielsen LL Pickett CB Liu S Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway Oncogene 2002, 21:2613-2622 10.1038/sj.onc.1205353 11965534
26. Ong V Liem NL Schmid MA Verrills NM Papa RA Marshall GM Mackenzie KL Kavallaris M Lock RB A role for altered microtubule polymer levels in vincristine resistance of childhood acute lymphoblastic leukemia xenografts J Pharmacol Exp Ther 2008, 324:434-442 10.1124/ jpet.107.128926 17986648
27. Joseph RA Shepard BD Kannarkat GT Rutledge TM Tuma DJ Tuma PL Microtubule acetylation and stability may explain alcohol-induced alterations in hepatic protein trafficking Hepatology 2008, 47:1745-1753 10.1002/hep.22014 18161881
28. Kannarkat GT Tuma DJ Tuma PL Microtubules are more stable and more highly acetylated in ethanol-treated hepatic cells J Hepatol 2006, 44:963-970 10.1016/j.jhep.2005.07.007 16169115
29. Wolf BB Schuler M Echeverri F Green DR Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/ inhibitor of caspase-activated DNase inactivation J Biol Chem 1999, 274:30651-30656 10.1074/jbc.274.43.30651 10521451
30. Janicke RU Sprengart ML Wati MR Porter AG Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis J Biol Chem 1998, 273:9357-9360 10.1074/jbc.273.16.9357 9545256
31. Wang X Yang C Chai J Shi Y Xue D Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans Science 2002, 298:1587-1592 10.1126/science.1076194 12446902
32. Lu CX Fan TJ Hu GB Cong RS Apoptosis-inducing factor and apoptosis Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 2003, 35:881-885 14515203
33. Tran J Master Z Yu JL Rak J Dumont DJ Kerbel RS A role for survivin in chemoresistance of endothelial cells mediated by VEGF Proc Natl Acad Sci USA 2002, 99:4349-4354 123651 11917134 10.1073/pnas.072586399
34. Nomura T Yamasaki M Nomura Y Mimata H Expression of the inhibitors of apoptosis proteins in cisplatin-resistant prostate cancer cells Oncol Rep 2005, 14:993-997 16142363
35. Zhang M Latham DE Delaney MA Chakravarti A Survivin mediates resistance to antiandrogen therapy in prostate cancer Oncogene 2005, 24:2474-2482 10.1038/sj.onc.1208490 15735703
36. Zhu N Gu L Findley HW Chen C Dong JT Yang L Zhou M KLF5 Interacts with p53 in regulating survivin expression in acute lymphoblastic leukemia J Biol Chem 2006, 281:14711-14718 10.1074/jbc.M513810200 16595680
37. Zhou M Gu L Li F Zhu Y Woods WG Findley HW DNA damage induces a novel p53-survivin signaling pathway regulating cell cycle and apoptosis in acute lymphoblastic leukemia cells J Pharmacol Exp Ther 2002, 303:124-131 10.1124/jpet.102.037192 12235242
38. Raj D Liu T Samadashwily G Li F Grossman D Survivin repression by p53, Rb and E2F2 in normal human melanocytes Carcinogenesis 2008, 29:194-201 2292458 17916908 10.1093/carcin/bgm219
39. Yonesaka K Tamura K Kurata T Satoh T Ikeda M Fukuoka M Nakagawa K Small interfering RNA targeting survivin sensitizes lung cancer cell with mutant p53 to adriamycin Int J Cancer 2006, 118:812-820 10.1002/ ijc.21350 16108013
40. Ikeda M Okamoto I Tamura K Satoh T Yonesaka K Fukuoka M Nakagawa K Down-regulation of survivin by ultraviolet C radiation is dependent on p53 and results in G(2)-M arrest in A549 cells Cancer Lett 2007, 248:292-298 10.1016/j.canlet.2006.08.005 16959403
41. Xia F Altieri DC Mitosis-independent survivin gene expression in vivo and regulation by p53 Cancer Res 2006, 66:3392-3395 10.1158/ 0008-5472.CAN-05-4537 16585159
42. Bajt ML Cover C Lemasters JJ Jaeschke H Nuclear translocation of endonuclease G and apoptosis-inducing factor during acetaminophen-induced liver cell injury Toxicological Sciences 2006, 94:217-225 10.1093/toxsci/kfl077 16896059
43. Ye H Cande C Stephanou NC Jiang S Gurbuxani S Larochette N Daugas E Garrido C Kroemer G Wu H DNA binding is required for the apoptogenic action of apoptosis inducing factor Nature Structural Biology 2002, 9:680-684 10.1038/nsb836 12198487
44. Hisatomi T Sakamoto T Murata T Yamanaka I Oshima Y Hata Y Ishibashi T Inomata H Susin SA Kroemer G Relocalization of apoptosis-inducing factor in photoreceptor apoptosis induced by retinal detachment in vivo American Journal of Pathology 2001, 158:1271-1278 1891920 11290545
45. Yan H Thomas J Liu T Raj D London N Tandeski T Leachman SA Lee RM Grossman D Induction of melanoma cell apoptosis and inhibition of tumor growth using a cell-permeable Survivin antagonist Oncogene 2006, 25:6968-6974 2292411 16702945 10.1038/sj.onc.1209676
46. Niikura Y Dixit A Scott R Perkins G Kitagawa K BUB1 mediation of caspase-independent mitotic death determines cell fate J Cell Biol 2007, 178:283-296 2064447 17620410 10.1083/jcb.200702134
47. Fujie Y Yamamoto H Ngan CY Takagi A Hayashi T Suzuki R Ezumi K Takemasa I Ikeda M Sekimoto M et al Oxaliplatin, a potent inhibitor of survivin, enhances paclitaxel-induced apoptosis and mitotic catastrophe in colon cancer cells Jpn J Clin Oncol 2005, 35:453-463 10.1093/jjco/hyi130 16024531
48. Hansen JB Fisker N Westergaard M Kjaerulff LS Hansen HF Thrue CA Rosenbohm C Wissenbach M Orum H Koch T SPC3042: A proapoptotic survivin inhibitor Mol Cancer Ther 2008, 7:2736-2745 10.1158/ 1535-7163.MCT-08-0161 18790754
49. Kamath K Wilson L Cabral F Jordan MA BetaIII-tubulin induces paclitaxel resistance in association with reduced effects on microtubule dynamic instability J Biol Chem 2005, 280:12902-12907 10.1074/jbc.M414477200 15695826