-
1
-
-
42349094203
-
Nanoparticles in medicine: Therapeutic applications and developments
-
Zhang, L.; Gu, F.X.; Chan, J.M.; Wang, A.Z.; Langer, R.S.; Farokhzad, O.C. Nanoparticles in medicine: therapeutic applications and developments. Clin. Pharm. Ther., 2008, 5(83), 761-769.
-
(2008)
Clin. Pharm. Ther.
, vol.5
, Issue.83
, pp. 761-769
-
-
Zhang, L.1
Gu, F.X.2
Chan, J.M.3
Wang, A.Z.4
Langer, R.S.5
Farokhzad, O.C.6
-
2
-
-
34248360301
-
Nanocarriers shape up for long life
-
Nishiyama, N. Nanocarriers shape up for long life. Nat. Nanotechnol., 2007, 2, 203-204.
-
(2007)
Nat. Nanotechnol.
, vol.2
, pp. 203-204
-
-
Nishiyama, N.1
-
3
-
-
0042899083
-
Blood brain barrier drug targeting: The future of brain drug development
-
Pardridge, W. M. Blood brain barrier drug targeting: the future of brain drug development. Mol. Interv., 2003, 3, 90-105.
-
(2003)
Mol. Interv.
, vol.3
, pp. 90-105
-
-
Pardridge, W.M.1
-
4
-
-
34249820576
-
Multi functional nanocarriers
-
Torchilin, V.P. Multi functional nanocarriers. Adv. Drug Deliv. Rev., 2006, 58, 1532-1555.
-
(2006)
Adv. Drug Deliv. Rev.
, vol.58
, pp. 1532-1555
-
-
Torchilin, V.P.1
-
8
-
-
0022626910
-
Blood-brain barrier: Interface between internal medicine and the brain
-
Pardridge, W.M. Blood-brain barrier: interface between internal medicine and the brain. Ann. Intern. Med., 1986, 105, 82-95.
-
(1986)
Ann. Intern. Med.
, vol.105
, pp. 82-95
-
-
Pardridge, W.M.1
-
9
-
-
29244463365
-
Astrocyte-endothelial interactions at the blood-brain barrier
-
Abbott, N.J.; Rönnbäck, L.; Hansson, E. Astrocyte-endothelial interactions at the blood-brain barrier. Nat. Rev. Neurosci., 2006, 7, 41-53.
-
(2006)
Nat. Rev. Neurosci.
, vol.7
, pp. 41-53
-
-
Abbott, N.J.1
Rönnbäck, L.2
Hansson, E.3
-
10
-
-
22944483792
-
The blood-brain barrier/neurovascular unit in health and disease
-
Hawkins, B.T.; Davis, T.P. The blood-brain barrier/neurovascular unit in health and disease. Pharmacol. Rev., 2005, 57, 173-185.
-
(2005)
Pharmacol. Rev.
, vol.57
, pp. 173-185
-
-
Hawkins, B.T.1
Davis, T.P.2
-
11
-
-
26244456551
-
Molecular biology of the blood-brain barrier
-
Pardridge W.M. Molecular biology of the blood-brain barrier. Mol. Biotechnol., 2005, 30, 57-69.
-
(2005)
Mol. Biotechnol.
, vol.30
, pp. 57-69
-
-
Pardridge, W.M.1
-
12
-
-
65949088798
-
Promises of nanotechnology for drug delivery to brain in neurodegenerative diseases
-
Baratchi, S.; Kanwar, R.K.; Khoshmanesh, K.; Vasu, P.; Chauhan, A.; Hittu, M.; Andrew, P.; Krishnakumar, S.; Sun, X.; Sahoo, S.K.: Kanwar, J.R. Promises of nanotechnology for drug delivery to brain in neurodegenerative diseases. Curr. Nanosci., 2009, 5(1), 15-25.
-
(2009)
Curr. Nanosci.
, vol.5
, Issue.1
, pp. 15-25
-
-
Baratchi, S.1
Kanwar, R.K.2
Khoshmanesh, K.3
Vasu, P.4
Chauhan, A.5
Hittu, M.6
Andrew, P.7
Krishnakumar, S.8
Sun, X.9
Sahoo, S.K.10
Kanwar, J.R.11
-
13
-
-
27944501073
-
Anti-inflammatory immmunotherapy for multiple sclerosis/experimental autoimmune encephalomyelitis (EAE) disease
-
DOI 10.2174/092986705774462833
-
Kanwar, J.R. Anti-inflammatory immunotherapy for multiple sclerosis/experimental autoimmune encephalomyelitis (EAE) disease. Curr. Med. Chem., 2005, 12(25), 2947-2962. (Pubitemid 41672485)
-
(2005)
Current Medicinal Chemistry
, vol.12
, Issue.25
, pp. 2947-2962
-
-
Kanwar, J.R.1
-
14
-
-
0033622029
-
β7 integrins contribute to demyelinating disease of the central nervous system
-
DOI 10.1016/S0165-5728(99)00245-3, PII S0165572899002453
-
Kanwar, J. R.; Harrison, J.E.B.; Wang, D.M.; Leung, E.; Mueller, W.; Wagner, N.; Krissansen, G.W. Beta 7 integrins contribute to demyelinating disease of the central nervous system. J. Neuroimmunol., 2000, 103(2), 146-152. (Pubitemid 30079726)
-
(2000)
Journal of Neuroimmunology
, vol.103
, Issue.2
, pp. 146-152
-
-
Kanwar, J.R.1
Harrison, J.E.B.2
Wang, D.3
Leung, E.4
Mueller, W.5
Wagner, N.6
Krissansen, G.W.7
-
15
-
-
0033667644
-
Prevention of a chronic progressive form of experimental autoimmune encephalomyelitisby an antibody against mucosal addressin cell adhesion molecule-1, given early in the course of disease progression
-
Kanwar, J.R.; Kanwar, R.K.; Wang, D. M.; Krissansen, G.W. Prevention of a chronic progressive form of experimental autoimmune encephalomyelitisby an antibody against mucosal addressin cell adhesion molecule-1, given early in the course of disease progression. Immunol. Cell Biol., 2000, 78(6), 641-645.
-
(2000)
Immunol. Cell Biol.
, vol.78
, Issue.6
, pp. 641-645
-
-
Kanwar, J.R.1
Kanwar, R.K.2
Wang, D.M.3
Krissansen, G.W.4
-
16
-
-
2942620628
-
Simultaneous neuroprotection and blockade of inflammation reverses autoimmune encephalomyelitis
-
Kanwar, J.R.; Kanwar, R.K.; Krissansen, G.W. Simultaneous neuroprotection and blockade of inflammation reverses autoimmune encephalomyelitis. Brain, 2004, 127(6), 1313-1331.
-
(2004)
Brain
, vol.127
, Issue.6
, pp. 1313-1331
-
-
Kanwar, J.R.1
Kanwar, R.K.2
Krissansen, G.W.3
-
17
-
-
0033546663
-
The effect of anti-alpha4 integrin antibody on brain lesion activity in multiple sclerosis
-
The UK Antegren Study Group
-
Tubridy, N.; Behan, P.O.; Capildeo, R.; Chaudhuri, A.; Forbes, R.; Hawkins, C.P. The effect of anti-alpha4 integrin antibody on brain lesion activity in multiple sclerosis. The UK Antegren Study Group. Neurology, 1999, 53, 466-472.
-
(1999)
Neurology
, vol.53
, pp. 466-472
-
-
Tubridy, N.1
Behan, P.O.2
Capildeo, R.3
Chaudhuri, A.4
Forbes, R.5
Hawkins, C.P.6
-
18
-
-
33747426294
-
A pseudosymmetric cell adhesion regulatory domain in the β7 tail of the integrin α4β7 that interacts with focal adhesion kinase and src
-
DOI 10.1002/eji.200535324
-
Krissansen, G.W.; Singh, J.; Kanwar, R.K.; Chan, Y.C.; Leung, E.; Lehnert, K.B.; Kanwar, J.R.; Yang, Y. A pseudosymmetric cell adhesion regulatory domain in the beta7 tail of the integrin alpha4beta7 that interacts with focal adhesion kinase and src. Eur. J. Immunol., 2006, 36(8), 2203-2214. (Pubitemid 44251765)
-
(2006)
European Journal of Immunology
, vol.36
, Issue.8
, pp. 2203-2214
-
-
Krissansen, G.W.1
Singh, J.2
Kanwar, R.K.3
Chan, Y.-C.4
Leung, E.5
Lenhert, K.B.6
Kanwar, J.R.7
Yang, Y.8
-
19
-
-
34547637590
-
Drug Targeting to the Brain
-
Pardridge, W.M. Drug Targeting to the Brain. Pharm. Res., 2007, 24(9), 1733-1744.
-
(2007)
Pharm. Res.
, vol.24
, Issue.9
, pp. 1733-1744
-
-
Pardridge, W.M.1
-
20
-
-
47749105642
-
Re-engineering protein pharmaceuticals for delivery to brain with molecular Trojan horses
-
Pardridge, W.M. Re-engineering protein pharmaceuticals for delivery to brain with molecular Trojan horses. Bioconjug. Chem., 2008, 19, 1327-1338.
-
(2008)
Bioconjug. Chem.
, vol.19
, pp. 1327-1338
-
-
Pardridge, W.M.1
-
21
-
-
33845784758
-
The blood brain barrier delivery
-
Pardridge, W.M. The blood brain barrier delivery. Drug. Discov. Today, 2007, 12, 54-61.
-
(2007)
Drug. Discov. Today
, vol.12
, pp. 54-61
-
-
Pardridge, W.M.1
-
22
-
-
0037435511
-
Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD
-
Nutt, J.G. Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD. Neurology, 2003, 60, 69-73. (Pubitemid 36070646)
-
(2003)
Neurology
, vol.60
, Issue.1
, pp. 69-73
-
-
Nutt, J.G.1
Burchiel, K.J.2
Comella, C.L.3
Jankovic, J.4
Lang, A.E.5
Laws Jr., E.R.6
Lozano, A.M.7
Penn, R.D.8
Simpson Jr., R.K.9
Stacy, M.10
Wooten, G.F.11
Johnston, L.12
Lopez, J.13
Harrigan, M.14
Marciano, F.F.15
Carter, J.H.16
Stone, C.17
Trugman, J.18
Rost-Ruffner, E.19
O'Brien, C.20
McVicker, J.H.21
Davis, T.L.22
Charles, D.23
Allen, G.24
Weiner, W.25
Landy, H.J.26
Bronstein, J.27
Koller, W.28
Pahwa, R.29
Wilkinson, S.30
Siemers, E.R.31
Wojcieszek, J.M.32
Witt, T.33
Tuite, P.J.34
Ebbitt, B.J.35
Maxwell, R.36
Cravets, M.37
Hilt, D.38
Klein, M.39
Lee, D.R.40
Schultz, B.41
more..
-
23
-
-
0029884848
-
Chemotherapeutic drugs released from polymers:Distribution of 1, 3-bis(2-chloroethyl)-1-nitrosourea in the rat brain
-
Fung, L.K. Chemotherapeutic drugs released from polymers:Distribution of 1, 3-bis(2-chloroethyl)-1-nitrosourea in the rat brain. Pharm. Res., 1996, 13, 671-682.
-
(1996)
Pharm. Res.
, vol.13
, pp. 671-682
-
-
Fung, L.K.1
-
24
-
-
0037911432
-
Intraputamenal infusion of GDNF in aged rhesus monkeys: Distribution and dopaminergic effects
-
DOI 10.1002/cne.10689
-
Ai, Y. Intraputamenal infusion of GDNF in aged rhesus monkeys: distribution and dopaminergic effects. J. Comp. Neurol., 2003, 461, 250-261. (Pubitemid 36583466)
-
(2003)
Journal of Comparative Neurology
, vol.461
, Issue.2
, pp. 250-261
-
-
Ai, Y.1
Markesbery, W.2
Zhang, Z.3
Grondin, R.4
Elseberry, D.5
Gerhardt, G.A.6
Gash, D.M.7
-
25
-
-
0020317797
-
Pharmacokinetics of progesterone after its administration to ovariectomized rhesus monkeys by injection, infusion, or nasal spraying
-
Anand Kumar, T.C.; David, G.F.; Sankaranarayanan, A.; Puri, V.; Sundram, K.R. Pharmacokinetics of progesterone after its administration to ovariectomized rhesus monkeys by injection, infusion, or nasal spraying. Proc. Natl. Acad. Sci. USA, 1982, 79, 4185-4189.
-
(1982)
Proc. Natl. Acad. Sci. USA
, vol.79
, pp. 4185-4189
-
-
Anand Kumar, T.C.1
David, G.F.2
Sankaranarayanan, A.3
Puri, V.4
Sundram, K.R.5
-
26
-
-
0037799484
-
Direct access of drugs to the human brain after intranasal drug administration?
-
F.W.
-
Merkus, P.; Guchelaar, H.J.; Bosch, D.A.; F.W. Merkus, D.A. Direct access of drugs to the human brain after intranasal drug administration? Neurology, 2003, 60, 1669-1671.
-
(2003)
Neurology
, vol.60
, pp. 1669-1671
-
-
Merkus, P.1
Guchelaar, H.J.2
Bosch, D.A.3
Merkus, D.A.4
-
27
-
-
0028944111
-
Plasma albumin is a potent trigger of calcium signals and DNA synthesis in astrocytes
-
Nadal, A. Plasma albumin is a potent trigger of calcium signals and DNA synthesis in astrocytes. Proc. Natl. Acad. Sci. USA, 1995, 92, 1426-1430.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 1426-1430
-
-
Nadal, A.1
-
28
-
-
0028866665
-
Scanning and transmission electron microscopic studies of microvascular pathology in the osmotically impaired blood-brain barrier
-
Lossinsky, A.S. Scanning and transmission electron microscopic studies of microvascular pathology in the osmotically impaired blood-brain barrier. Neurocytology, 1995, 24, 795-806.
-
(1995)
Neurocytology
, vol.24
, pp. 795-806
-
-
Lossinsky, A.S.1
-
29
-
-
0024206648
-
Structural changes in the rat brain after carotid infusions of hyperosmolar solutions. An electron microscopic study
-
DOI 10.1007/BF00688236
-
Salahuddin, T.S. Structural changes in the rat brain after carotid infusions of hyperosmolar solutions. An electron microscopic study. Acta Neuropathol., (Berl.), 1988 , 77, 5-13. (Pubitemid 19002265)
-
(1988)
Acta Neuropathologica
, vol.77
, Issue.1
, pp. 5-13
-
-
Salahuddin, T.S.1
Johansson, B.B.2
Kalimo, H.3
Olsson, Y.4
-
30
-
-
0002595302
-
Targeting rat anti-mouse transferrin receptor monoclonal antibodies through the blood-brain barrier in the mouse
-
Lee, H.J.; Engelhardt, B.; Lesley, J.; Bickel, U.; Pardridge, W.M. Targeting rat anti-mouse transferrin receptor monoclonal antibodies through the blood-brain barrier in the mouse. J. Pharmacol. Exp. Ther., 2000, 292, 1048-1052.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.292
, pp. 1048-1052
-
-
Lee, H.J.1
Engelhardt, B.2
Lesley, J.3
Bickel, U.4
Pardridge, W.M.5
-
31
-
-
0033996507
-
Transport across the primate blood-brain barrier of a genetically engineered chimeric monoclonal antibody to the human insulin receptor
-
Coloma, M.J.; Lee, H.J.; Kurihara, A.; Landaw, E.M.; Boado, R.J.; Morrison, S.L.; Pardridge, W.M. Transport across the primate blood-brain barrier of a genetically engineered chimeric monoclonal antibody to the human insulin receptor. Pharm. Res., 2000, 17(3), 266-274.
-
(2000)
Pharm. Res.
, vol.17
, Issue.3
, pp. 266-274
-
-
Coloma, M.J.1
Lee, H.J.2
Kurihara, A.3
Landaw, E.M.4
Boado, R.J.5
Morrison, S.L.6
Pardridge, W.M.7
-
32
-
-
0030426639
-
Central nervous system pharmacologic effect in conscious rats after intravenous injection of a biotinylated vasoactive intestinal peptide analog coupled to a blood-brain barrier drug delivery system
-
Wu, D.; Pardridge, W.M. Central nervous system pharmacologic effect in conscious rats after intravenous injection of a biotinylated vasoactive intestinal peptide analog coupled to a blood-brain barrier drug delivery system. J. Pharmacol. Exp. Ther., 1996, 279, 77-83.
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.279
, pp. 77-83
-
-
Wu, D.1
Pardridge, W.M.2
-
33
-
-
0034988984
-
Neuroprotection in transient focal brain ischemia after delayed intravenous administration of brain-derived neurotrophic factor conjugated to a blood-brain barrier drug targeting system
-
Zhang, Y.; Pardridge, W.M. Neuroprotection in transient focal brain ischemia after delayed intravenous administration of brain-derived neurotrophic factor conjugated to a blood-brain barrier drug targeting system. Stroke, 2001, 32, 1378-1384.
-
(2001)
Stroke
, vol.32
, pp. 1378-1384
-
-
Zhang, Y.1
Pardridge, W.M.2
-
34
-
-
0036228917
-
Enhanced neuroprotective effects of basic fibroblast growth factor in regional brain ischemia after conjugation to a blood-brain barrier delivery vector
-
Song, B.W. Enhanced neuroprotective effects of basic fibroblast growth factor in regional brain ischemia after conjugation to a blood-brain barrier delivery vector. J. Pharmacol. Exp. Ther., 2002, 301, 605-610.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.301
, pp. 605-610
-
-
Song, B.W.1
-
35
-
-
0036173189
-
Imaging brain amyloid of Alzheimer disease in vivo in transgenic mice with an Abeta peptide radiopharmaceutical
-
Lee, H.J. Imaging brain amyloid of Alzheimer disease in vivo in transgenic mice with an Abeta peptide radiopharmaceutical. J. Cereb. Blood Flow Metab., 2002, 22, 223-231.
-
(2002)
J. Cereb. Blood Flow Metab.
, vol.22
, pp. 223-231
-
-
Lee, H.J.1
-
37
-
-
0028233389
-
Glycopeptide enkephalin analogues produce analgesia in mice: Evidence for penetration of the blood-brain barrier
-
Polt, R.; Porreca, F.; Szabo, L.Z.; Bilsky, E.J.; Davis, P.; Abbruscato, T.J.; Davis, T.P.; Harvath, R.; Yamamura, H.I.; Hruby, V.J. Glycopeptide enkephalin analogues produce analgesia in mice: evidence for penetration of the blood-brain barrier. Proc. Natl. Acad. Sci. USA, 1994, 91, 7114-7118.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7114-7118
-
-
Polt, R.1
Porreca, F.2
Szabo, L.Z.3
Bilsky, E.J.4
Davis, P.5
Abbruscato, T.J.6
Davis, T.P.7
Harvath, R.8
Yamamura, H.I.9
Hruby, V.J.10
-
38
-
-
0038296015
-
Glycopeptide-membrane interactions: Glycosyl enkephalin analogues adopt turn conformations by NMR and CD in amphipathic media
-
DOI 10.1021/ja0268635
-
Palian, M.M.; Boguslavsky, V.I.; O'Brien, D.F.; Polt, R. Glycopeptide-membrane interactions: glycosyl enkephalin analogues adopt turn conformations by NMR and CD in amphipathic media. J. Am. Chem. Soc., 2003, 125, 5823-5831. (Pubitemid 36592908)
-
(2003)
Journal of the American Chemical Society
, vol.125
, Issue.19
, pp. 5823-5831
-
-
Palian, M.M.1
Boguslavsky, V.I.2
O'Brien, D.F.3
Polt, R.4
-
39
-
-
0034693398
-
Improved bioavailability to the brain of glycosylated Met-enkephalin analogs
-
Egleton, R.D.; Mitchell, S.A.; Huber, J.D.; Janders, J.; Stropova, D.; Polt, R.; Yamamura, H.I.; Hruby, V.J.; Davis, T.P. Improved bioavailability to the brain of glycosylated Met-enkephalin analogs. Brain Res., 2000, 881, 37-46.
-
(2000)
Brain Res.
, vol.881
, pp. 37-46
-
-
Egleton, R.D.1
Mitchell, S.A.2
Huber, J.D.3
Janders, J.4
Stropova, D.5
Polt, R.6
Yamamura, H.I.7
Hruby, V.J.8
Davis, T.P.9
-
40
-
-
0035167372
-
Liposomes (a review), part one: Manufacturing issues
-
Chrai. SS.; Murari, R.; Ahmad, I. Liposomes (a review), part one: manufacturing issues. BioPharm., 2001, 14(11), 10-14.
-
(2001)
BioPharm.
, vol.14
, Issue.11
, pp. 10-14
-
-
Chrai, S.S.1
Murari, R.2
Ahmad, I.3
-
41
-
-
31344441398
-
Molecular modeling of blood-brain barrier nutrient transporters: In silico basis for evaluation of potential drug delivery to the central nervous system
-
Allen, D.D.; Geldenhuys, W.J. Molecular modeling of blood-brain barrier nutrient transporters: in silico basis for evaluation of potential drug delivery to the central nervous system. Life Sci., 2006, 78(10), 1029-1033
-
(2006)
Life Sci.
, vol.78
, Issue.10
, pp. 1029-1033
-
-
Allen, D.D.1
Geldenhuys, W.J.2
-
42
-
-
0035940380
-
Brain-specific expression of an exogenous gene after i.v. administration
-
DOI 10.1073/pnas.221450098
-
Shi, N.; Zhang, Y.; Zhu, C.; Boado, R.J.; Pardridge, W.M. Brain-specific expression of an exogenous gene after i.v. administration. Proc. Natl. Acad. Sci. USA, 2001, 98, 12754-12759. (Pubitemid 33026054)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.22
, pp. 12754-12759
-
-
Shi, N.1
Zhang, Y.2
Zhu, C.3
Boado, R.J.4
Pardridge, W.M.5
-
43
-
-
0042768492
-
In vivo delivery of glial cell-derived neurotrophic factor across the blood-brain barrier by gene transfer into brain capillary endothelial cells
-
DOI 10.1089/104303403322168019
-
Jiang, C.; Koyabu, N.; Yonemitsu, Y.; Shimazoe, T.; Watanabe, S.; Naito, M.; Tsuruo, T.; Ohtani, H.; Sawada, Y. In vivo delivery of glial cell-derived neurotrophic factor across the blood-brain barrier by gene transfer into brain capillary endothelial cells. Hum. Gene Ther., 2003, 14, 1181-1191. (Pubitemid 36930407)
-
(2003)
Human Gene Therapy
, vol.14
, Issue.12
, pp. 1181-1191
-
-
Jiang, C.1
Koyabu, N.2
Yonemitsu, Y.3
Shimazoe, T.4
Watanabe, S.5
Naito, M.6
Tsuruo, T.7
Ohtani, H.8
Sawada, Y.9
-
44
-
-
0035984822
-
Transluminal gene transfer into brain capillary endothelial cells in vivo with HVJ-liposomes
-
Jiang, C.; Matsuo, H.; Koyabu, N.; Ohtani, H.; Fujimoto, H.; Yonemitsu,Y.; Kaneda, Y.; Narro, M.;, Tsuruo, T.; Sawada, Y. Transluminal gene transfer into brain capillary endothelial cells in vivo with HVJ-liposomes. J. Drug Target, 2002, 10(4), 345-352.
-
(2002)
J. Drug Target
, vol.10
, Issue.4
, pp. 345-352
-
-
Jiang, C.1
Matsuo, H.2
Koyabu, N.3
Ohtani, H.4
Fujimoto, H.5
Yonemitsu, Y.6
Kaneda, Y.7
Narro, M.8
Tsuruo, T.9
Sawada, Y.10
-
45
-
-
0029931964
-
Drug delivery to the brain using thermosensitive liposome and local hyperthermia
-
Kakinuma, K.; Tanaka, R.; Takahashi, H.; Sekihara, Y.; Watanabe, M.; Kuroki, M. Drug delivery to the brain using thermosensitive liposome and local hyperthermia. Int. J. Hyperthermia, 1996, 12, 157-165. (Pubitemid 26096974)
-
(1996)
International Journal of Hyperthermia
, vol.12
, Issue.1
, pp. 157-165
-
-
Kakinuma, K.1
Tanaka, R.2
Takahashi, H.3
Sekihara, Y.4
Watanabe, M.5
Kuroki, M.6
-
46
-
-
0043028168
-
RGD-anchored magnetic liposomes for monocytes/neutrophils-mediated brain targeting
-
Jain, S.; Mishra, V.; Singh, P.; Dubey, P. K.; Saraf, D. K.; Vyas, S.P. RGD-anchored magnetic liposomes for monocytes/neutrophils-mediated brain targeting. Int. J. Pharm., 2003, 261, 43-55.
-
(2003)
Int. J. Pharm.
, vol.261
, pp. 43-55
-
-
Jain, S.1
Mishra, V.2
Singh, P.3
Dubey, P.K.4
Saraf, D.K.5
Vyas, S.P.6
-
47
-
-
0033800767
-
Non-stealth and stealth solid lipid nanoparticles (sln) carrying doxorubicin: Pharmacokinetic and tissue distribution after i.v. administration to rats
-
Fundaro, A.; Cavalli, R.; Bagoni, A.; Vighetto, D.; Zara, G.P.; Gasco, M.R. Non-stealth and stealth solid lipid nanoparticles (sln) carrying doxorubicin: pharmacokinetic and tissue distribution after i.v. administration to rats. Pharm. Res., 2000, 42, 337-343.
-
(2000)
Pharm. Res.
, vol.42
, pp. 337-343
-
-
Fundaro, A.1
Cavalli, R.2
Bagoni, A.3
Vighetto, D.4
Zara, G.P.5
Gasco, M.R.6
-
48
-
-
1342312020
-
Novel delivery systems for drug targeting to the brain
-
DOI 10.1358/dof.2004.029.01.872585
-
Reddy, J.S.; Venkateshwarlu, V. Novel delivery systems for drug targetingto the brain, Drugs Future, 2004, 29, 63-83. (Pubitemid 38252080)
-
(2004)
Drugs of the Future
, vol.29
, Issue.1
, pp. 63-83
-
-
Suresh Reddy, J.1
Venkateswarlu, V.2
-
49
-
-
0034760365
-
In vitro and in vivo study of two types of long-circulating solid lipid nanoparticles containing paclitaxel
-
DOI 10.1248/cpb.49.1444
-
Chen, D.; Yang, T.; Liang, W.; Zhang, Q. In vitro and in vivo study of two types of long circulating solid lipid nanoparticles containing Paclitaxel. Chem. Pharm. Bull., 2001, 49, 1444-1447. (Pubitemid 33043274)
-
(2001)
Chemical and Pharmaceutical Bulletin
, vol.49
, Issue.11
, pp. 1444-1447
-
-
Chen, D.-B.1
Yang, T.-Z.2
Lu, W.-L.3
Zhang, Q.4
-
50
-
-
0035984818
-
Intravenous administration to rabbits of non-stealth and stealth doxorubicin-loaded solid lipid nanoparticles at increasing concentrations of stealth agent: Pharmacokinetics and distribution of doxorubicin in brain and other tissues
-
Zara, G.P.; Cavalli, R.; Bargoni, A.; Fundaro, A.; Vighetto, D.; Gasco, M.R. Intravenous administration to rabbits of non-stealth and stealth doxorubicin-loaded solid lipid nanoparticles at increasing concentrations of stealth agent: pharmacokinetics and distribution of doxorubicin in brain and other tissues. J. Drug Target, 2002, 10, 327-335.
-
(2002)
J. Drug Target
, vol.10
, pp. 327-335
-
-
Zara, G.P.1
Cavalli, R.2
Bargoni, A.3
Fundaro, A.4
Vighetto, D.5
Gasco, M.R.6
-
51
-
-
33750833782
-
Pharmacokinetics, tissue distributionand bioavalability of nitrendipine solid lipid nanoparticles after intravenous and intraduodenal administration
-
Manjunath, K.; Venkateshwarlu, V. Pharmacokinetics, tissue distributionand bioavalability of nitrendipine solid lipid nanoparticles after intravenous and intraduodenal administration. J. Drug Target, 2006, 14(9), 632-645.
-
(2006)
J. Drug Target
, vol.14
, Issue.9
, pp. 632-645
-
-
Manjunath, K.1
Venkateshwarlu, V.2
-
52
-
-
0036848464
-
Enhanced brain targeting by synthesis of 3',5'-dioctanoyl-5-fluoro-2'- deoxyuridine and incorporation into solid lipid nanoparticles
-
Wang, J.X.; Sun, X.; Zhang, Z.R. Enhanced brain targeting by synthesis of 3',5'-dioctanoyl-5-fluoro-2'-deoxyuridine and incorporation into solid lipid nanoparticles. Eur. J. Pharm. Biopharm., 2002, 54(3), 285-290.
-
(2002)
Eur. J. Pharm. Biopharm.
, vol.54
, Issue.3
, pp. 285-290
-
-
Wang, J.X.1
Sun, X.2
Zhang, Z.R.3
-
53
-
-
0043062820
-
Surface-engineered nanoparticles for multiple ligand coupling
-
DOI 10.1016/S0142-9612(03)00348-X
-
Gref, R.; Couvreur, P.; Barratt, G.; Mysiakine, E. Surface-engineered nanoparticles for multiple ligand coupling. Biomaterials, 2003, 24, 4529-4537 (Pubitemid 36960147)
-
(2003)
Biomaterials
, vol.24
, Issue.24
, pp. 4529-4537
-
-
Gref, R.1
Couvreur, P.2
Barratt, G.3
Mysiakine, E.4
-
54
-
-
0035937595
-
Nanoparticulate systems for brain delivery of drugs
-
DOI 10.1016/S0169-409X(00)00122-8, PII S0169409X00001228
-
Kreuter, J. Nanoparticulate systems for brain delivery of drugs. Adv. Drug Deliv. Rev., 2001, 47, 65-81. (Pubitemid 32209233)
-
(2001)
Advanced Drug Delivery Reviews
, vol.47
, Issue.1
, pp. 65-81
-
-
Kreuter, J.1
-
55
-
-
18244415517
-
Méthodes d'obtention et mécanismes de formation de nanoparticules polymériques
-
Montasser, I.; Briancon, S.; Lieto, J.; Fessi, H. Obtaining methods and formation mechanisms of polymeric nanoparticles. J. Pharm. Belg., 2000, 6, 155-167. (Pubitemid 32054879)
-
(2000)
Journal de Pharmacie de Belgique
, vol.55
, Issue.6
, pp. 155-167
-
-
Montasser, I.1
Briancon, S.2
Lieto, J.3
Fessi, H.4
-
56
-
-
23444444512
-
Biodegradable long-circulating polymeric nanospheres
-
Gref, R.; Minamitake, Y.; Peracchia, M.T.; Trubetskoy, V.; Torchilin, V.; Langer, R. Biodegradable long-circulating polymeric nanospheres. Science, 1994, 263, 1600-1603.
-
(1994)
Science
, vol.263
, pp. 1600-1603
-
-
Gref, R.1
Minamitake, Y.2
Peracchia, M.T.3
Trubetskoy, V.4
Torchilin, V.5
Langer, R.6
-
57
-
-
0034781649
-
Biodistribution of long-circulating PEG-grafted nanocapsules in mice: Effects of PEG chain length and density
-
DOI 10.1023/A:1012248721523
-
Mosqueira, V.C.F.; Legrand, P.; Morgat, J.L.; Vert, M.; Mysiakine, E.; Gref, R. Biodistribution of long-circulating PEG-grafted nanocapsules in mice: effects of PEG chain length and density. Pharm Res., 2001, 18, 1411-1419. (Pubitemid 32977246)
-
(2001)
Pharmaceutical Research
, vol.18
, Issue.10
, pp. 1411-1419
-
-
Mosqueira, V.C.F.1
Legrand, P.2
Morgat, J.-L.3
Vert, M.4
Mysiakine, E.5
Gref, R.6
Devissaguet, J.-P.7
Barratt, G.8
-
58
-
-
0031783879
-
Chitosan and its use as a pharmaceutical excipient
-
Illum, L. Chitosan and its use as a pharmaceutical excipient. Pharm Res., 1998, 15, 1326-1331.
-
(1998)
Pharm Res.
, vol.15
, pp. 1326-1331
-
-
Illum, L.1
-
59
-
-
39849104152
-
Development and in vitro evaluation of alginate gel-encapsulated, chitosan-coated ceramicnanocores for oral delivery of enzyme
-
Rawat, M.; Singh, S.; Saraf, S.; Saraf, S. Development and in vitro evaluation of alginate gel-encapsulated, chitosan-coated ceramicnanocores for oral delivery of enzyme. Drug Dev. Ind. Pharm., 2008, 34, 181-188.
-
(2008)
Drug Dev. Ind. Pharm.
, vol.34
, pp. 181-188
-
-
Rawat, M.1
Singh, S.2
Saraf, S.3
Saraf, S.4
-
60
-
-
0034118297
-
Polysorbate-80 coating enhances uptake of polybutylcyanoacrylate (PBCA)-nanoparticles by human and bovine primary brain capillary endothelial cells
-
Ramge, P.; Unger, R.E.; Oltrogge, J.B.; Zenker, D.; Begley, D.; Kreuter, J.; Polysorbate-80 coating enhances uptake of polybutylcyanoacrylate (PBCA)-nanoparticles by human and bovine primary brain capillary endothelial cells. Eur. J. Neurosci., 2000, 12, 1931-1940.
-
(2000)
Eur. J. Neurosci.
, vol.12
, pp. 1931-1940
-
-
Ramge, P.1
Unger, R.E.2
Oltrogge, J.B.3
Zenker, D.4
Begley, D.5
Kreuter, J.6
-
61
-
-
0030853702
-
Influence of the type of surfactant on the analgesic effects induced by the peptide dalargin after its delivery across the blood-brain barrier using surfactant-coated nanoparticles
-
Kreuter, J.; Petrov, V.E.; Kharkevich, D.A.; Alyautdin, R.N. Influence of the type of surfactant on the analgesic effects induced by the peptide dalargin after its delivery across the blood-brain barrier using surfactant-coated nanoparticles. J. Control. Release, 1997, 49, 81-87.
-
(1997)
J. Control. Release
, vol.49
, pp. 81-87
-
-
Kreuter, J.1
Petrov, V.E.2
Kharkevich, D.A.3
Alyautdin, R.N.4
-
62
-
-
0033427851
-
Indirect evidence that drug brain targeting using polysorbate 80- Coated polybutylcyanoacrylate nanoparticles is related to toxicity
-
Olivier, J.C.; Fenart, L.; Chauvet, R.; Pariat, C.; Cecchell, R.I.; Couet, W. Indirect evidence that drug brain targeting using polysorbate 80-coated polybutylcyanoacrylate nanoparticles is related to toxicity. Pharm. Res., 1999, 16, 1836-1842. (Pubitemid 30040699)
-
(1999)
Pharmaceutical Research
, vol.16
, Issue.12
, pp. 1836-1842
-
-
Olivier, J.-C.1
Fenart, L.2
Chauvet, R.3
Pariat, C.4
Cecchelli, R.5
Couet, W.6
-
63
-
-
0037335187
-
Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles
-
Kreuter, J.; Ramge, P.; Petrov, V.; Hamm, S.; Svetlana, E.; Gelperina.; Engelhardt, B.; Alyautdin, R.; Briesen, H.; Begley D. J. Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles. Pharm. Res., 2003, 20(3), 409-416.
-
(2003)
Pharm. Res.
, vol.20
, Issue.3
, pp. 409-416
-
-
Kreuter, J.1
Ramge, P.2
Petrov, V.3
Hamm, S.4
Svetlana, E.5
Gelperina6
Engelhardt, B.7
Alyautdin, R.8
Briesen, H.9
Begley, D.J.10
-
64
-
-
54849430738
-
The first step into the brain: Uptake of NIO-PBCA nanoparticles by endothelial cells in vitro and in vivo, and direct evidence for their blood-brain barrier permeation
-
Weiss, C.K.; Kohnle, M.V.; Landfester, K.; Hauk, T.; Fischer, D.; Wienke, J.S.; Mailnder,V. The first step into the brain: uptake of NIO-PBCA nanoparticles by endothelial cells in vitro and in vivo, and direct evidence for their blood-brain barrier permeation. Chem. Med. Chem., 2008, 3, 1395-1403.
-
(2008)
Chem. Med. Chem.
, vol.3
, pp. 1395-1403
-
-
Weiss, C.K.1
Kohnle, M.V.2
Landfester, K.3
Hauk, T.4
Fischer, D.5
Wienke, J.S.6
Mailnder, V.7
-
65
-
-
21344466290
-
Double-coated poly (butylcynanoacrylate) nanoparticulate delivery systems for brain targeting of dalargin via oral administration
-
DOI 10.1002/jps.20357
-
Das. D.; Lin, S. Double-coated poly (butylcynanoacrylate) nanoparticulate delivery systems for brain targeting of dalargin via oral administration. J. Pharm. Sci., 2005, 94(6), 1343-1353. (Pubitemid 40904197)
-
(2005)
Journal of Pharmaceutical Sciences
, vol.94
, Issue.6
, pp. 1343-1353
-
-
Das, D.1
Lin, S.2
-
66
-
-
50149094833
-
Targeted delivery of tacrine into the brain with polysorbate 80-coated poly(n-butylcyanoacrylate) nanoparticles
-
Wilson, B.; Samanta, M.K.; Santhi, K.; Kumar, K.P.; Paramakrishnan, N.; Suresh, B. Targeted delivery of tacrine into the brain with polysorbate 80-coated poly(n-butylcyanoacrylate) nanoparticles. Eur. J. Pharm. Biopharm., 2008, 70(1), 75-84.
-
(2008)
Eur. J. Pharm. Biopharm.
, vol.70
, Issue.1
, pp. 75-84
-
-
Wilson, B.1
Samanta, M.K.2
Santhi, K.3
Kumar, K.P.4
Paramakrishnan, N.5
Suresh, B.6
-
67
-
-
40849097322
-
Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease
-
Wilson, B.; Samanta, M.K.; Santhi, K.; Perumal, K.; Kumar, S.; Paramakrishnan,N.; Bhojraj, S.; .Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease. Brain Res., 2008, 1200, 159-168.
-
(2008)
Brain Res.
, vol.1200
, pp. 159-168
-
-
Wilson, B.1
Samanta, M.K.2
Santhi, K.3
Perumal, K.4
Kumar, S.5
Paramakrishnan, N.6
Bhojraj, S.7
-
68
-
-
34548041658
-
Targeting the central nervous system: In vivo experiments with peptide-derivatized nanoparticles loaded with Loperamide and Rhodamine-123
-
DOI 10.1016/j.jconrel.2007.05.022, PII S0168365907002660
-
Tosi, G.; Costantino, L.; Rivasi, F.; Ruozi, B.; Leo, E.; Vergoni, A.V.; Tacchi, R.; Bertolini, A.; Vandelli, M.A.; Forni, F. Targeting the central nervous system: in vivo experiments with peptide-derivatized nanoparticles loaded with Loperamide and Rhodamine-123. J. Control. Release, 2007, 122, 1-9. (Pubitemid 47284547)
-
(2007)
Journal of Controlled Release
, vol.122
, Issue.1
, pp. 1-9
-
-
Tosi, G.1
Costantino, L.2
Rivasi, F.3
Ruozi, B.4
Leo, E.5
Vergoni, A.V.6
Tacchi, R.7
Bertolini, A.8
Vandelli, M.A.9
Forni, F.10
-
69
-
-
52949107192
-
Delivery of nanoparticles to the brain detected by fluorescence microscopy
-
Reimold, I.; Domke, D.; Bender, J.; Seyfried, C. A.; Radunz, H. E.; Fricker, G. Delivery of nanoparticles to the brain detected by fluorescence microscopy. Eur. J. Pharm. Biopharm., 2008, 70, 627-632.
-
(2008)
Eur. J. Pharm. Biopharm.
, vol.70
, pp. 627-632
-
-
Reimold, I.1
Domke, D.2
Bender, J.3
Seyfried, C.A.4
Radunz, H.E.5
Fricker, G.6
-
70
-
-
34547655840
-
Brain delivery of vasoactive intestinal peptide enhanced with the nanoparticles conjugated with wheat germ agglutinin following intranasal administration
-
DOI 10.1016/j.jconrel.2007.05.026, PII S0168365907002702
-
Gao, X.; Wu, B.; Zhang, Q.; Chen, J.; Zhu, J.; Zhang, W.; Rong, Z.; Chen, H.; Jiang, X. Brain delivery of vasoactive intestinal peptide enhanced with the nanoparticles conjugated with wheat germ agglutinin following intranasal administration. J. Control. Release, 2007, 121, 156-167. (Pubitemid 47212537)
-
(2007)
Journal of Controlled Release
, vol.121
, Issue.3
, pp. 156-167
-
-
Gao, X.1
Wu, B.2
Zhang, Q.3
Chen, J.4
Zhu, J.5
Zhang, W.6
Rong, Z.7
Chen, H.8
Jiang, X.9
-
71
-
-
17644410724
-
Cationic albumin conjugated pegylated nanoparticle with its transcytosis ability and little toxicity against blood-brain barrier
-
Lu, W.; Tan, Y.Z.; Hu, K.L.; Jiang, X.G. Cationic albumin conjugated pegylated nanoparticle with its transcytosis ability and little toxicity against blood-brain barrier. Int. J. Pharm., 2005, 295, 247-260.
-
(2005)
Int. J. Pharm.
, vol.295
, pp. 247-260
-
-
Lu, W.1
Tan, Y.Z.2
Hu, K.L.3
Jiang, X.G.4
-
72
-
-
33847116764
-
Covalent attachment of apolipoprotein A-I and apolipoprotein B-100 to albumin nanoparticles enables drug transport into the brain
-
DOI 10.1016/j.jconrel.2006.12.012, PII S0168365906007103
-
Kreuter, J.; Hekmatara, T.; Dreis, S.; Vogel, T.; Gelperina, S.; Langer, K. Covalent attachment of apolipoprotein A-I and apolipoprotein B-100 to albumin nanoparticles enables drug transport into the brain. J. Control. Release, 2007, 118, 54-58. (Pubitemid 46283106)
-
(2007)
Journal of Controlled Release
, vol.118
, Issue.1
, pp. 54-58
-
-
Kreuter, J.1
Hekmatara, T.2
Dreis, S.3
Vogel, T.4
Gelperina, S.5
Langer, K.6
-
73
-
-
59649102668
-
Transferrin- and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood-brain barrier (BBB)
-
Ulbrich, K.; Hekmatara, T.; Herbert, E.; Kreuter, J. Transferrin- and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood-brain barrier (BBB). Eur. J. Pharm. Biopharm., 2009, 71(2), 251-256.
-
(2009)
Eur. J. Pharm. Biopharm.
, vol.71
, Issue.2
, pp. 251-256
-
-
Ulbrich, K.1
Hekmatara, T.2
Herbert, E.3
Kreuter, J.4
-
74
-
-
58149129243
-
Consequence of Abeta immunization on the vasculature of human Alzheimer's disease brain
-
Boche, D.; Zotova, E.; Weller, R.O.; Love, S.; Neal, J.W.; Pickering, R.M.; Wilkinson, D.; Holmes, C.; Nicoll, J.A. Consequence of Abeta immunization on the vasculature of human Alzheimer's disease brain. Brain, 2008, 131, 3299-3310.
-
(2008)
Brain
, vol.131
, pp. 3299-3310
-
-
Boche, D.1
Zotova, E.2
Weller, R.O.3
Love, S.4
Neal, J.W.5
Pickering, R.M.6
Wilkinson, D.7
Holmes, C.8
Nicoll, J.A.9
-
75
-
-
20044375981
-
Cerebral amyloid angiopathy and dementia
-
Tian, J.; Shi, J.; Mann, DM. Cerebral amyloid angiopathy and dementia. Panminerva Med., 2004, 46, 253-264.
-
(2004)
Panminerva Med.
, vol.46
, pp. 253-264
-
-
Tian, J.1
Shi, J.2
Mann, D.M.3
-
76
-
-
33646673555
-
A review of nanocarrier-based CNS delivery systems
-
Tiwari, S.B.; Amiji, M.M. A review of nanocarrier-based CNS delivery systems. Curr. Drug Deliv., 2006, 21, 219-232.
-
(2006)
Curr. Drug Deliv.
, vol.21
, pp. 219-232
-
-
Tiwari, S.B.1
Amiji, M.M.2
|