-
1
-
-
33947216271
-
Can matrix metalloproteinase inhibitors provide a realistic therapy in cardiovascular medicine?
-
MacFadyen, R.J. Can matrix metalloproteinase inhibitors provide a realistic therapy in cardiovascular medicine? Curr. Opin. Pharmacol., 2007, 7, 171-178.
-
(2007)
Curr. Opin. Pharmacol
, vol.7
, pp. 171-178
-
-
Macfadyen, R.J.1
-
2
-
-
52949084668
-
Progress in matrix metalloproteinase research
-
Murphy, G.; Nagase, H. Progress in matrix metalloproteinase research. Mol. Aspects Med., 2008, 29, 290-308.
-
(2008)
Mol. Aspects Med
, vol.29
, pp. 290-308
-
-
Murphy, G.1
Nagase, H.2
-
3
-
-
0034472617
-
Matrix metalloproteinases in tumor invasion and metastasis
-
Stamenkovic, I. Matrix metalloproteinases in tumor invasion and metastasis. Semin. Cancer Biol., 2000, 10, 415-433.
-
(2000)
Semin. Cancer Biol
, vol.10
, pp. 415-433
-
-
Stamenkovic, I.1
-
4
-
-
2342637653
-
Matrix metalloproteinase inhibitors
-
Ramnath, N.; Creaven, P.J. Matrix metalloproteinase inhibitors. Curr. Oncol. Rep., 2004, 6, 96-102.
-
(2004)
Curr. Oncol. Rep
, vol.6
, pp. 96-102
-
-
Ramnath, N.1
Creaven, P.J.2
-
5
-
-
74949125629
-
Assessment of aprotinin influence on periodontal clinical status and matrix metalloproteinases 1, 2 and their tissue inhibitors saliva concentrations in patients with chronic periodontitis
-
Pietruska, M.; Pietruski, J.; Skurska, A.; Bernaczyk, A.; Zak, J.; Zelazowska, B.; Doli, E.; Paniczko-Drezek, A.; Wysocka, J. Assessment of aprotinin influence on periodontal clinical status and matrix metalloproteinases 1, 2 and their tissue inhibitors saliva concentrations in patients with chronic periodontitis. Adv. Med. Sci., 2009, 54, 239-246.
-
(2009)
Adv. Med. Sci
, vol.54
, pp. 239-246
-
-
Pietruska, M.1
Pietruski, J.2
Skurska, A.3
Bernaczyk, A.4
Zak, J.5
Zelazowska, B.6
Doli, E.7
Paniczko-Drezek, A.8
Wysocka, J.9
-
6
-
-
70349811339
-
Matrix metalloproteinases in subjects with type 1 diabetes
-
Gharagozlian, S.; Svennevig, K.; Bangstad, H.J.; Winberg, J.O.; Kolset, S.O. Matrix metalloproteinases in subjects with type 1 diabetes. BMC. Clin. Pathol., 2009, 9, 7.
-
(2009)
BMC. Clin. Pathol
, vol.9
, pp. 7
-
-
Gharagozlian, S.1
Svennevig, K.2
Bangstad, H.J.3
Winberg, J.O.4
Kolset, S.O.5
-
7
-
-
70449732763
-
Matrix metalloproteinase (MMP)-9, but not MMP-2, is involved in the development and progression of C protein-induced myocarditis and subsequent dilated cardiomyopathy
-
Matsumoto, Y.; Park, I.K.; Kohyama, K. Matrix metalloproteinase (MMP)-9, but not MMP-2, is involved in the development and progression of C protein-induced myocarditis and subsequent dilated cardiomyopathy. J. Immunol., 2009, 183, 4773-4781.
-
(2009)
J. Immunol
, vol.183
, pp. 4773-4781
-
-
Matsumoto, Y.1
Park, I.K.2
Kohyama, K.3
-
8
-
-
34447520043
-
Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases
-
Hu, J.; Van den Steen, P.E.; Sang, Q.X.; Opdenakker, G. Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases. Nat. Rev. Drug Discov., 2007, 6, 480-498.
-
(2007)
Nat. Rev. Drug Discov
, vol.6
, pp. 480-498
-
-
Hu, J.1
van den Steen, P.E.2
Sang, Q.X.3
Opdenakker, G.4
-
9
-
-
33646136687
-
Matrix metalloproteinase inhibitors as prospective agents for the prevention and treatment of cardiovascular and neoplastic diseases
-
Sang, Q.X.; Jin, Y.; Newcomer, R.G.; Monroe, S.C.; Fang, X.; Hurst, D.R.; Lee, S.; Cao, Q.; Schwartz, M.A. Matrix metalloproteinase inhibitors as prospective agents for the prevention and treatment of cardiovascular and neoplastic diseases. Curr. Top Med. Chem., 2006, 6, 289-316.
-
(2006)
Curr. Top Med. Chem
, vol.6
, pp. 289-316
-
-
Sang, Q.X.1
Jin, Y.2
Newcomer, R.G.3
Monroe, S.C.4
Fang, X.5
Hurst, D.R.6
Lee, S.7
Cao, Q.8
Schwartz, M.A.9
-
10
-
-
66949138615
-
Role of matrix metalloproteinases in coronary artery disease
-
Shah, V.K.; Shalia, K.K.; Mashru, M.R.; Soneji, S.L.; Abraham, A.; Kudalkar, K.V.; Vasvani, J.B.; Sanghavi, S.T. Role of matrix metalloproteinases in coronary artery disease. Indian Heart J., 2009, 61, 44-50.
-
(2009)
Indian Heart J
, vol.61
, pp. 44-50
-
-
Shah, V.K.1
Shalia, K.K.2
Mashru, M.R.3
Soneji, S.L.4
Abraham, A.5
Kudalkar, K.V.6
Vasvani, J.B.7
Sanghavi, S.T.8
-
11
-
-
34547617698
-
Targeting matrix metalloproteinases and endothelial cells with a fusion peptide against tumor
-
Zou, Y.; Chen, Y.; Jiang, Y.; Gao, J.; Gu, J. Targeting matrix metalloproteinases and endothelial cells with a fusion peptide against tumor. Cancer Res., 2007, 67, 7295-7300.
-
(2007)
Cancer Res
, vol.67
, pp. 7295-7300
-
-
Zou, Y.1
Chen, Y.2
Jiang, Y.3
Gao, J.4
Gu, J.5
-
12
-
-
0001651169
-
Design and therapeutic application of matrix metalloproteinase inhibitors
-
Whittaker, M.; Floyd, C.D.; Brown, P.; Gearing, A.J. Design and therapeutic application of matrix metalloproteinase inhibitors. Chem. Rev., 1999, 99, 2735-2776.
-
(1999)
Chem. Rev
, vol.99
, pp. 2735-2776
-
-
Whittaker, M.1
Floyd, C.D.2
Brown, P.3
Gearing, A.J.4
-
13
-
-
34447269445
-
Matrix metalloproteinase inhibitors: New challenges in the era of post broad-spectrum inhibitors
-
Nuti, E.; Tuccinardi, T.; Rossello, A. Matrix metalloproteinase inhibitors: New challenges in the era of post broad-spectrum inhibitors. Curr. Pharm. Des., 2007, 13, 2087-2100.
-
(2007)
Curr. Pharm. Des
, vol.13
, pp. 2087-2100
-
-
Nuti, E.1
Tuccinardi, T.2
Rossello, A.3
-
15
-
-
33644545381
-
Tumour microenvironment-opinion: Validating matrix metalloproteinases as drug targets and antitargets for cancer therapy
-
Overall, C.M.; Kleifeld, O. Tumour microenvironment-opinion: Validating matrix metalloproteinases as drug targets and antitargets for cancer therapy. Nat. Rev. Cancer., 2006, 6, 227-239.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 227-239
-
-
Overall, C.M.1
Kleifeld, O.2
-
16
-
-
0032439091
-
Matrix metalloproteinase inhibitors
-
Brown, P.D. Matrix metalloproteinase inhibitors. Breast Cancer Res. Treat., 1998, 52, 125-136.
-
(1998)
Breast Cancer Res. Treat
, vol.52
, pp. 125-136
-
-
Brown, P.D.1
-
17
-
-
43049142648
-
Matrix metalloproteinase inhibitors as anticancer agents
-
Konstantinopoulos, P.A.; Karamouzis, M.V.; Papatsoris, A.G.; Papavassiliou, A.G. Matrix metalloproteinase inhibitors as anticancer agents. Int. J. Biochem. Cell Biol., 2008, 40, 1156-1168.
-
(2008)
Int. J. Biochem. Cell Biol
, vol.40
, pp. 1156-1168
-
-
Konstantinopoulos, P.A.1
Karamouzis, M.V.2
Papatsoris, A.G.3
Papavassiliou, A.G.4
-
18
-
-
15244342010
-
Matrix metalloproteinases as therapeutic targets in cancer
-
Vihinen, P.; Ala-aho, R.; Kahari, V.M. Matrix metalloproteinases as therapeutic targets in cancer. Curr. Cancer Drug Targets, 2005, 5, 203-220.
-
(2005)
Curr. Cancer Drug Targets
, vol.5
, pp. 203-220
-
-
Vihinen, P.1
Ala-Aho, R.2
Kahari, V.M.3
-
19
-
-
33646584823
-
Recent advances in MMP inhibitor design
-
Fisher, J.F.; Mobashery, S. Recent advances in MMP inhibitor design. Cancer Metastasis. Rev., 2006, 25, 115-136.
-
(2006)
Cancer Metastasis. Rev
, vol.25
, pp. 115-136
-
-
Fisher, J.F.1
Mobashery, S.2
-
20
-
-
0037975559
-
Broad-spectrum matrix metalloproteinase inhibitor Marimastat-induced musculoskeletal side effects in rats
-
Renkiewicz, R.; Qiu, L.; Lesch, C.; Sun, X.; Devalaraja, R.; Cody, T.; Kaldjian. E. Welgus, H. Baragi, V. Broad-spectrum matrix metalloproteinase inhibitor Marimastat-induced musculoskeletal side effects in rats. Arthritis. Rheum., 2003, 48, 1742-1749.
-
(2003)
Arthritis. Rheum
, vol.48
, pp. 1742-1749
-
-
Renkiewicz, R.1
Qiu, L.2
Lesch, C.3
Sun, X.4
Devalaraja, R.5
Cody, T.6
Kaldjian, E.7
Welgus, H.8
Baragi, V.9
-
21
-
-
21344466344
-
Matrix metalloproteinase inhibitors as anticancer therapeutics
-
Mannello, F.; Tonti, G.; Papa, S. Matrix metalloproteinase inhibitors as anticancer therapeutics. Curr. Cancer Drug Targets, 2005, 5, 285-298.
-
(2005)
Curr. Cancer Drug Targets
, vol.5
, pp. 285-298
-
-
Mannello, F.1
Tonti, G.2
Papa, S.3
-
22
-
-
0037192458
-
Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
-
Coussens, L.M.; Fingleton, B.; Matrisian, L.M. Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science, 2002, 295, 2387-2392.
-
(2002)
Science
, vol.295
, pp. 2387-2392
-
-
Coussens, L.M.1
Fingleton, B.2
Matrisian, L.M.3
-
23
-
-
0035030734
-
The design, structure, and therapeutic application of matrix metalloproteinase inhibitors
-
Skiles, J.W.; Gonnella, N.C.; Jeng, A.Y. The design, structure, and therapeutic application of matrix metalloproteinase inhibitors. Curr. Med. Chem., 2001, 8, 425-474.
-
(2001)
Curr. Med. Chem
, vol.8
, pp. 425-474
-
-
Skiles, J.W.1
Gonnella, N.C.2
Jeng, A.Y.3
-
24
-
-
5744249740
-
The design, structure, and clinical update of small molecular weight matrix metalloproteinase inhibitors
-
Skiles, J.W.; Gonnella, N.C.; Jeng, A.Y. The design, structure, and clinical update of small molecular weight matrix metalloproteinase inhibitors. Curr. Med. Chem., 2004, 11, 2911-2977.
-
(2004)
Curr. Med. Chem
, vol.11
, pp. 2911-2977
-
-
Skiles, J.W.1
Gonnella, N.C.2
Jeng, A.Y.3
-
25
-
-
18444397733
-
Crystal structure of human MMP9 in complex with a reverse hydroxamate inhibitor
-
Rowsell, S.; Hawtin, P.; Minshull, C.A.; Jepson, H.; Brockbank, S.M.; Barratt, D.G.; Slater, A.M.; McPheat, W.L.; Waterson, D.; Henney, A.M.; Pauptit, R.A. Crystal structure of human MMP9 in complex with a reverse hydroxamate inhibitor. J. Mol. Biol., 2002, 319, 173-181.
-
(2002)
J. Mol. Biol
, vol.319
, pp. 173-181
-
-
Rowsell, S.1
Hawtin, P.2
Minshull, C.A.3
Jepson, H.4
Brockbank, S.M.5
Barratt, D.G.6
Slater, A.M.7
McPheat, W.L.8
Waterson, D.9
Henney, A.M.10
Pauptit, R.A.11
-
26
-
-
0035064033
-
X-ray structure of a novel matrix metalloproteinase inhibitor complexed to stromelysin
-
Dunten, P.; Kammlott, U.; Crowther, R.; Levin, W.; Foley, L.H.; Wang, P.; Palermo, R. X-ray structure of a novel matrix metalloproteinase inhibitor complexed to stromelysin. Protein Sci., 2001, 10, 923-926.
-
(2001)
Protein Sci
, vol.10
, pp. 923-926
-
-
Dunten, P.1
Kammlott, U.2
Crowther, R.3
Levin, W.4
Foley, L.H.5
Wang, P.6
Palermo, R.7
-
27
-
-
0037142342
-
Structural differences of matrix metalloproteinases with potential implications for inhibitor selectivity examined by the GRID/CPCA approach
-
Terp, G.E.; Cruciani, G.; Christensen, I.T.; Jørgensen, F.S. Structural differences of matrix metalloproteinases with potential implications for inhibitor selectivity examined by the GRID/CPCA approach. J. Med. Chem., 2002, 45, 2675-2684.
-
(2002)
J. Med. Chem
, vol.45
, pp. 2675-2684
-
-
Terp, G.E.1
Cruciani, G.2
Christensen, I.T.3
Jørgensen, F.S.4
-
28
-
-
77149131528
-
To bind zinc or not to bind zinc: An examination of innovative approaches to improved metalloproteinase inhibition
-
Jacobsen, J.A.; Major Jourden, J.L.; Miller, M.T.; Cohen, S.M. To bind zinc or not to bind zinc: An examination of innovative approaches to improved metalloproteinase inhibition. Biochim. Biophys. Acta, 2010, 1803(1), 72-94.
-
(2010)
Biochim. Biophys. Acta
, vol.1803
, Issue.1
, pp. 72-94
-
-
Jacobsen, J.A.1
Major Jourden, J.L.2
Miller, M.T.3
Cohen, S.M.4
-
29
-
-
52949136266
-
Specific targeting of metzincin family members with small-molecule inhibitors: Progress toward a multifarious challenge
-
Georgiadis, D.; Yiotakis, A. Specific targeting of metzincin family members with small-molecule inhibitors: Progress toward a multifarious challenge. Bioorg. Med. Chem., 2008, 16, 8781-8794.
-
(2008)
Bioorg. Med. Chem
, vol.16
, pp. 8781-8794
-
-
Georgiadis, D.1
Yiotakis, A.2
-
30
-
-
0033082368
-
CD13--not just a marker in leukemia typing
-
Riemann, D.; Kehlen, A.; Langner, J. CD13--not just a marker in leukemia typing. Immunol. Today, 1999, 20, 83-88.
-
(1999)
Immunol. Today
, vol.20
, pp. 83-88
-
-
Riemann, D.1
Kehlen, A.2
Langner, J.3
-
31
-
-
0347626098
-
Biological significance of aminopeptidase N/CD13 in thyroid carcinomas
-
Kehlen, A.; Lendeckel, U.; Dralle, H.; Langner, J.; Hoang-Vu, C. Biological significance of aminopeptidase N/CD13 in thyroid carcinomas. Cancer Res., 2003, 63, 8500-8506.
-
(2003)
Cancer Res
, vol.63
, pp. 8500-8506
-
-
Kehlen, A.1
Lendeckel, U.2
Dralle, H.3
Langner, J.4
Hoang-Vu, C.5
-
32
-
-
38449084605
-
DP IV/CD26, APN/CD13 and related enzymes as regulators of T cell immunity: Implications for experimental encephalomyelitis and multiple sclerosis
-
Reinhold, D.; Bank, U.; Täger, M.; Ansorge, S.; Wrenger, S.; Thielitz, A.; Lendeckel, U.; Faust, J.; Neubert, K.; Brocke, S. DP IV/CD26, APN/CD13 and related enzymes as regulators of T cell immunity: implications for experimental encephalomyelitis and multiple sclerosis. Front. Biosci., 2008, 13, 2356-2363.
-
(2008)
Front. Biosci
, vol.13
, pp. 2356-2363
-
-
Reinhold, D.1
Bank, U.2
Täger, M.3
Ansorge, S.4
Wrenger, S.5
Thielitz, A.6
Lendeckel, U.7
Faust, J.8
Neubert, K.9
Brocke, S.10
-
33
-
-
37549035458
-
Aminopeptidase N (APN)/CD13-dependent CXCR4 downregulation is associated with diminished cell migration, proliferation and invasion
-
Wulfaenger, J.; Niedling, S.; Riemann, D.; Seliger, B. Aminopeptidase N (APN)/CD13-dependent CXCR4 downregulation is associated with diminished cell migration, proliferation and invasion. Mol. Membr. Biol., 2008, 25, 72-82.
-
(2008)
Mol. Membr. Biol
, vol.25
, pp. 72-82
-
-
Wulfaenger, J.1
Niedling, S.2
Riemann, D.3
Seliger, B.4
-
34
-
-
0029100416
-
Human melanoma invasion and metastasis enhancement by high expression of aminopeptidase N/CD13
-
Fujii, H.; Nakajima, M.; Saiki, I.; Yoneda, J.; Azuma, I.; Tsuruo, T. Human melanoma invasion and metastasis enhancement by high expression of aminopeptidase N/CD13. Clin. Exp. Metastasis, 1995, 13, 337-344.
-
(1995)
Clin. Exp. Metastasis
, vol.13
, pp. 337-344
-
-
Fujii, H.1
Nakajima, M.2
Saiki, I.3
Yoneda, J.4
Azuma, I.5
Tsuruo, T.6
-
35
-
-
0035314018
-
Aminopeptidase N regulated by zinc in human prostate participates in tumor cell invasion
-
Ishii, K.; Usui, S.; Sugimura, Y.; Yoshida, S.; Hioki, T.; Tatematsu, M.; Yamamoto, H.; Hirano, K. Aminopeptidase N regulated by zinc in human prostate participates in tumor cell invasion. Int. J. Cancer, 2001, 92, 49-54.
-
(2001)
Int. J. Cancer
, vol.92
, pp. 49-54
-
-
Ishii, K.1
Usui, S.2
Sugimura, Y.3
Yoshida, S.4
Hioki, T.5
Tatematsu, M.6
Yamamoto, H.7
Hirano, K.8
-
36
-
-
0034659306
-
Angiogenesis: New insights and therapeutic potential
-
Tomanek, R.J.; Schatteman, G.C. Angiogenesis: new insights and therapeutic potential. Anat. Rec., 2000, 261, 126-135.
-
(2000)
Anat. Rec
, vol.261
, pp. 126-135
-
-
Tomanek, R.J.1
Schatteman, G.C.2
-
37
-
-
33749449024
-
Aminopeptidase N (APN/CD13) is selectively expressed in vascular endothelial cells and plays multiple roles in angiogenesis
-
Fukasawa, K.; Fujii, H.; Saitoh, Y.; Koizumi, K.; Aozuka, Y.; Sekine, K.; Yamada, M.; Saiki, I.; Nishikawa, K. Aminopeptidase N (APN/CD13) is selectively expressed in vascular endothelial cells and plays multiple roles in angiogenesis. Cancer Lett., 2006, 243, 135-143.
-
(2006)
Cancer Lett
, vol.243
, pp. 135-143
-
-
Fukasawa, K.1
Fujii, H.2
Saitoh, Y.3
Koizumi, K.4
Aozuka, Y.5
Sekine, K.6
Yamada, M.7
Saiki, I.8
Nishikawa, K.9
-
38
-
-
0035254206
-
CD13/APN is activated by angiogenic signals and is essential for capillary tube formation
-
Bhagwat, S.V.; Lahdenranta, J.; Giordano, R.; Arap, W.; Pasqualini, R.; Shapiro, L.H. CD13/APN is activated by angiogenic signals and is essential for capillary tube formation. Blood, 2001, 97, 652-659.
-
(2001)
Blood
, vol.97
, pp. 652-659
-
-
Bhagwat, S.V.1
Lahdenranta, J.2
Giordano, R.3
Arap, W.4
Pasqualini, R.5
Shapiro, L.H.6
-
39
-
-
0036161112
-
Aminopeptidase N is involved in cell motility and angiogenesis: Its clinical significance in human colon cancer
-
Hashida, H.; Takabayashi, A.; Kanai, M.; Adachi, M.; Kondo, K.; Kohno, N.; Yamaoka, Y.; Miyake, M. Aminopeptidase N is involved in cell motility and angiogenesis: its clinical significance in human colon cancer. Gastroenterology, 2002, 122, 376-386.
-
(2002)
Gastroenterology
, vol.122
, pp. 376-386
-
-
Hashida, H.1
Takabayashi, A.2
Kanai, M.3
Adachi, M.4
Kondo, K.5
Kohno, N.6
Yamaoka, Y.7
Miyake, M.8
-
40
-
-
48149111676
-
The moonlighting enzyme CD13: Old and new functions to target
-
Mina-Osorio, P. The moonlighting enzyme CD13: old and new functions to target. Trends Mol. Med., 2008, 14, 361-371.
-
(2008)
Trends Mol. Med
, vol.14
, pp. 361-371
-
-
Mina-Osorio, P.1
-
41
-
-
33845954688
-
Crystal structure of aminopeptidase N (proteobacteria alanyl aminopeptidase) from Escherichia coli and conformational change of methionine 260 involved in substrate recognition
-
Ito, K.; Nakajima, Y.; Onohara, Y.; Takeo, M.; Nakashima, K.; Matsubara, F.; Ito, T.; Yoshimoto, T. Crystal structure of aminopeptidase N (proteobacteria alanyl aminopeptidase) from Escherichia coli and conformational change of methionine 260 involved in substrate recognition. J. Biol. Chem., 2006, 281, 33664-33676.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 33664-33676
-
-
Ito, K.1
Nakajima, Y.2
Onohara, Y.3
Takeo, M.4
Nakashima, K.5
Matsubara, F.6
Ito, T.7
Yoshimoto, T.8
-
42
-
-
33745713183
-
Crystallization and preliminary X-ray characterization of aminopeptidase N from Escherichia coli
-
Onohara, Y.; Nakajima, Y.; Ito, K.; Xu, Y.; Nakashima, K.; Ito, T.; Yoshimoto, T. Crystallization and preliminary X-ray characterization of aminopeptidase N from Escherichia coli. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., 2006, 62, 699-701.
-
(2006)
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun
, vol.62
, pp. 699-701
-
-
Onohara, Y.1
Nakajima, Y.2
Ito, K.3
Xu, Y.4
Nakashima, K.5
Ito, T.6
Yoshimoto, T.7
-
43
-
-
43249098656
-
Structural basis for the unusual specificity of Escherichia coli aminopeptidase N
-
Addlagatta, A.; Gay, L.; Matthews, B.W. Structural basis for the unusual specificity of Escherichia coli aminopeptidase N. Biochemistry, 2008, 47, 5303-5311.
-
(2008)
Biochemistry
, vol.47
, pp. 5303-5311
-
-
Addlagatta, A.1
Gay, L.2
Matthews, B.W.3
-
44
-
-
33748629692
-
Structure of aminopeptidase N from Escherichia coli suggests a compartmentalized, gated active site
-
Addlagatta, A.; Gay, L.; Matthews, B.W. Structure of aminopeptidase N from Escherichia coli suggests a compartmentalized, gated active site. Proc. Natl. Acad. Sci. U S A., 2006, 103, 13339-13344.
-
(2006)
Proc. Natl. Acad. Sci. U S A
, vol.103
, pp. 13339-13344
-
-
Addlagatta, A.1
Gay, L.2
Matthews, B.W.3
-
45
-
-
0034719482
-
Structure-activity relationships and pharmacokinetic analysis for a series of potent, systemically available biphenylsulfonamide matrix metalloproteinase inhibitors
-
O'Brien, P.M.; Ortwine, D.F.; Pavlovsky, A.G.; Picard, J.A.; Sliskovic, D.R.; Roth, B.D.; Dyer, R.D.; Johnson, L.L.; Man, C.F.; Hallak, H. Structure-activity relationships and pharmacokinetic analysis for a series of potent, systemically available biphenylsulfonamide matrix metalloproteinase inhibitors. J. Med. Chem., 2000, 43, 156-166.
-
(2000)
J. Med. Chem
, vol.43
, pp. 156-166
-
-
O'Brien, P.M.1
Ortwine, D.F.2
Pavlovsky, A.G.3
Picard, J.A.4
Sliskovic, D.R.5
Roth, B.D.6
Dyer, R.D.7
Johnson, L.L.8
Man, C.F.9
Hallak, H.10
-
46
-
-
1842828874
-
New radioiodinated carboxylic and hydroxamic matrix metalloproteinase inhibitor tracers as potential tumor imaging agents
-
Oltenfreiter, R.; Staelens, L.; Lejeune, A.; Dumont, F.; Frankenne, F.; Foidart, J.M.; Slegers, G. New radioiodinated carboxylic and hydroxamic matrix metalloproteinase inhibitor tracers as potential tumor imaging agents. Nucl. Med. Biol., 2004, 31, 459-468.
-
(2004)
Nucl. Med. Biol
, vol.31
, pp. 459-468
-
-
Oltenfreiter, R.1
Staelens, L.2
Lejeune, A.3
Dumont, F.4
Frankenne, F.5
Foidart, J.M.6
Slegers, G.7
-
47
-
-
0033619976
-
Design, synthesis, and biological evaluation of matrix metalloproteinase inhibitors derived from a modified proline scaffold
-
Cheng, M.; De, B.; Almstead, N.G.; Pikul, S.; Dowty, M.E.; Dietsch, C.R.; Dunaway, C.M.; Gu, F.; Hsieh, L.C.; Janusz, M.J.; Taiwo, Y.O.; Natchus, M.G.; Hudlicky, T.; Mandel, M. Design, synthesis, and biological evaluation of matrix metalloproteinase inhibitors derived from a modified proline scaffold. J. Med. Chem., 1999, 42, 5426-5436.
-
(1999)
J. Med. Chem
, vol.42
, pp. 5426-5436
-
-
Cheng, M.1
De, B.2
Almstead, N.G.3
Pikul, S.4
Dowty, M.E.5
Dietsch, C.R.6
Dunaway, C.M.7
Gu, F.8
Hsieh, L.C.9
Janusz, M.J.10
Taiwo, Y.O.11
Natchus, M.G.12
Hudlicky, T.13
Mandel, M.14
-
48
-
-
5444231462
-
A ligand-based molecular modeling study on some matrix metalloproteinase-1 inhibitors using several 3D QSAR techniques
-
Tsai, K.C.; Lin, T.H. A ligand-based molecular modeling study on some matrix metalloproteinase-1 inhibitors using several 3D QSAR techniques. J. Chem. Inf. Comput. Sci., 2004, 44, 1857-1871.
-
(2004)
J. Chem. Inf. Comput. Sci
, vol.44
, pp. 1857-1871
-
-
Tsai, K.C.1
Lin, T.H.2
-
49
-
-
0034727847
-
Development of new hydroxamate matrix metalloproteinase inhibitors derived from functionalized 4-aminoprolines
-
Natchus, M.G.; Bookland, R.G.; De, B.; Almstead, N.G.; Pikul, S.; Janusz, M.J.; Heitmeyer, S.A.; Hookfin, E.B.; Hsieh, L.C.; Dowty, M.E.; Dietsch, C.R.; Patel, V.S.; Garver, S.M.; Gu, F.; Pokross, M.E.; Mieling, G.E.; Baker, T.R.; Foltz, D.J.; Peng, S.X.; Bornes, D.M.; Strojnowski, M.J.; Taiwo, Y.O. Development of new hydroxamate matrix metalloproteinase inhibitors derived from functionalized 4-aminoprolines. J. Med. Chem., 2000, 43, 4948-4963.
-
(2000)
J. Med. Chem
, vol.43
, pp. 4948-4963
-
-
Natchus, M.G.1
Bookland, R.G.2
De, B.3
Almstead, N.G.4
Pikul, S.5
Janusz, M.J.6
Heitmeyer, S.A.7
Hookfin, E.B.8
Hsieh, L.C.9
Dowty, M.E.10
Dietsch, C.R.11
Patel, V.S.12
Garver, S.M.13
Gu, F.14
Pokross, M.E.15
Mieling, G.E.16
Baker, T.R.17
Foltz, D.J.18
Peng, S.X.19
Bornes, D.M.20
Strojnowski, M.J.21
Taiwo, Y.O.22
more..
-
50
-
-
0037401628
-
A quantitative structureactivity relationship study of hydroxamate matrix metalloproteinase inhibitors derived from functionalized 4-aminoprolines
-
Gupta, S.P.; Kumar, D.; Kumaran, S. A quantitative structureactivity relationship study of hydroxamate matrix metalloproteinase inhibitors derived from functionalized 4-aminoprolines. Bioorg. Med. Chem., 2003, 11, 1975-1981.
-
(2003)
Bioorg. Med. Chem
, vol.11
, pp. 1975-1981
-
-
Gupta, S.P.1
Kumar, D.2
Kumaran, S.3
-
51
-
-
33645832556
-
Comparison of the pharmacology of hydroxamate and carboxylate-based matrix metalloproteinase inhibitors (MMPIs) for the treatment of osteoarthritis
-
Janusz, M.J.; Hookfin, E.B.; Brown, K.K.; Hsieh, L.C.; Heitmeyer, S.A.; Taiwo, Y.O.; Natchus, M.G.; Pikul, S.; Almstead, N.G.; De, B.; Peng, S.X.; Baker, T.R.; Patel, V. Comparison of the pharmacology of hydroxamate and carboxylate-based matrix metalloproteinase inhibitors (MMPIs) for the treatment of osteoarthritis. Inflamm. Res., 2006, 55, 60-65.
-
(2006)
Inflamm. Res
, vol.55
, pp. 60-65
-
-
Janusz, M.J.1
Hookfin, E.B.2
Brown, K.K.3
Hsieh, L.C.4
Heitmeyer, S.A.5
Taiwo, Y.O.6
Natchus, M.G.7
Pikul, S.8
Almstead, N.G.9
De, B.10
Peng, S.X.11
Baker, T.R.12
Patel, V.13
-
52
-
-
0038351836
-
Protease inhibitors: Synthesis of bacterial collagenase and matrix metalloproteinase inhibitors incorporating succinyl hydroxamate and iminodiacetic acid hydroxamate moieties
-
Santos, M.A.; Marques, S.; Gil, M.; Tegoni, M.; Scozzafava, A.; Supuran, C.T. Protease inhibitors: synthesis of bacterial collagenase and matrix metalloproteinase inhibitors incorporating succinyl hydroxamate and iminodiacetic acid hydroxamate moieties J. Enzyme Inhib. Med. Chem., 2003, 18, 233-242.
-
(2003)
J. Enzyme Inhib. Med. Chem
, vol.18
, pp. 233-242
-
-
Santos, M.A.1
Marques, S.2
Gil, M.3
Tegoni, M.4
Scozzafava, A.5
Supuran, C.T.6
-
54
-
-
0035030734
-
The design, structure, and therapeutic application of matrix metalloproteinase inhibitors
-
Skiles, J.W.; Gonnella, N.C.; Jeng, A.Y. The design, structure, and therapeutic application of matrix metalloproteinase inhibitors. Curr. Med. Chem., 2001, 8, 425-474.
-
(2001)
Curr. Med. Chem
, vol.8
, pp. 425-474
-
-
Skiles, J.W.1
Gonnella, N.C.2
Jeng, A.Y.3
-
55
-
-
33645738383
-
Towards third generation matrix metalloproteinase inhibitors for cancer therapy
-
Overall, C.M.; Kleifeld, O. Towards third generation matrix metalloproteinase inhibitors for cancer therapy. Br. J. Cancer, 2006, 94, 941-946.
-
(2006)
Br. J. Cancer
, vol.94
, pp. 941-946
-
-
Overall, C.M.1
Kleifeld, O.2
-
56
-
-
0033048045
-
Crystal structures of MMP-1 and -13 reveal the structural basis for selectivity of collagenase inhibitors
-
Lovejoy, B.; Welch, A.R.; Carr, S.; Luong, C.; Broka, C.; Hendricks, R.T.; Campbell, J.A.; Walker, K.A. Martin, R.; Van Wart, H.; Browner, M.F. Crystal structures of MMP-1 and -13 reveal the structural basis for selectivity of collagenase inhibitors. Nat. Struct. Biol., 1999, 6(3), 217-221.
-
(1999)
Nat. Struct. Biol
, vol.6
, Issue.3
, pp. 217-221
-
-
Lovejoy, B.1
Welch, A.R.2
Carr, S.3
Luong, C.4
Broka, C.5
Hendricks, R.T.6
Campbell, J.A.7
Walker, K.A.8
Martin, R.9
van Wart, H.10
Browner, M.F.11
-
57
-
-
33846906016
-
Matrix metalloproteinases (MMPs): Chemical-biological functions and (Q)SARs
-
Verma, R.P.; Hansch, C. Matrix metalloproteinases (MMPs): chemical-biological functions and (Q)SARs. Bioorg. Med. Chem., 2007, 15, 2223-2268.
-
(2007)
Bioorg. Med. Chem
, vol.15
, pp. 2223-2268
-
-
Verma, R.P.1
Hansch, C.2
-
58
-
-
64349106309
-
Extra binding region induced by non-zinc chelating inhibitors into the S1' subsite of matrix metalloproteinase 8 (MMP8)
-
Pochetti, G.; Montanari, R.; Gege, C.; Chevrier, C.; Taveras, A.G.; Mazza, F. Extra binding region induced by non-zinc chelating inhibitors into the S1' subsite of matrix metalloproteinase 8 (MMP8). J. Med. Chem., 2009, 52, 1040-1049.
-
(2009)
J. Med. Chem
, vol.52
, pp. 1040-1049
-
-
Pochetti, G.1
Montanari, R.2
Gege, C.3
Chevrier, C.4
Taveras, A.G.5
Mazza, F.6
-
59
-
-
52949113083
-
Synthetic active site-directed inhibitors of metzincins: Achievement and perspectives
-
Yiotakis, A.; Dive, V. Synthetic active site-directed inhibitors of metzincins: achievement and perspectives. Mol. Aspects Med., 2008, 29, 329-338.
-
(2008)
Mol. Aspects Med
, vol.29
, pp. 329-338
-
-
Yiotakis, A.1
Dive, V.2
-
60
-
-
0038038524
-
Structural basis for potent slow binding inhibition of human matrix metalloproteinase-2 (MMP-2)
-
Rosenblum, G.; Meroueh, S.O.; Kleifeld, O.; Brown, S.; Singson, S.P.; Fridman, R.; Mobashery, S.; Sagi, I. Structural basis for potent slow binding inhibition of human matrix metalloproteinase-2 (MMP-2). J. Biol. Chem., 2003, 278, 27009-27015.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 27009-27015
-
-
Rosenblum, G.1
Meroueh, S.O.2
Kleifeld, O.3
Brown, S.4
Singson, S.P.5
Fridman, R.6
Mobashery, S.7
Sagi, I.8
-
61
-
-
33646804364
-
Development of selective inhibitors and substrate of matrix metalloproteinase-12
-
Devel, L.; Rogakos, V.; David, A.; Makaritis, A.; Beau, F.; Cuniasse, P.; Yiotakis, A.; Dive, V. Development of selective inhibitors and substrate of matrix metalloproteinase-12. J. Biol. Chem., 2006, 281, 11152-11160.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 11152-11160
-
-
Devel, L.1
Rogakos, V.2
David, A.3
Makaritis, A.4
Beau, F.5
Cuniasse, P.6
Yiotakis, A.7
Dive, V.8
-
62
-
-
14144252682
-
Structural basis for the highly selective inhibition of MMP-13
-
Engel, C.K.; Pirard, B.; Schimanski, S.; Kirsch, R.; Habermann, J.; Klingler, O.; Schlotte, V.; Weithmann, K.U.; Wendt, K.U. Structural basis for the highly selective inhibition of MMP-13. Chem. Biol., 2005, 12, 181-189.
-
(2005)
Chem. Biol
, vol.12
, pp. 181-189
-
-
Engel, C.K.1
Pirard, B.2
Schimanski, S.3
Kirsch, R.4
Habermann, J.5
Klingler, O.6
Schlotte, V.7
Weithmann, K.U.8
Wendt, K.U.9
-
63
-
-
0035855834
-
Design and synthesis of matrix metalloproteinase inhibitors guided by molecular modeling. Picking the S(1) pocket using conformationally constrained inhibitors
-
Hanessian, S.; MacKay, D.B.; Moitessier, N. Design and synthesis of matrix metalloproteinase inhibitors guided by molecular modeling. Picking the S(1) pocket using conformationally constrained inhibitors. J. Med. Chem., 2001, 44, 3074-3082.
-
(2001)
J. Med. Chem
, vol.44
, pp. 3074-3082
-
-
Hanessian, S.1
Mackay, D.B.2
Moitessier, N.3
-
64
-
-
33646186011
-
Linear and nonlinear QSAR study of N-hydroxy-2-[(phenylsulfonyl)amino] acetamide derivatives as matrix metalloproteinase inhibitors
-
Fernández, M.; Caballero, J.; Tundidor-Camba, A. Linear and nonlinear QSAR study of N-hydroxy-2-[(phenylsulfonyl)amino] acetamide derivatives as matrix metalloproteinase inhibitors. Bioorg. Med. Chem., 2006, 14, 4137-4150.
-
(2006)
Bioorg. Med. Chem
, vol.14
, pp. 4137-4150
-
-
Fernández, M.1
Caballero, J.2
Tundidor-Camba, A.3
-
65
-
-
0035935192
-
AlphaAlkyl-alpha-amino-beta-sulphone hydroxamates as potent MMP inhibitors that spare MMP-1
-
Becker, D.P.; DeCrescenzo, G.; Freskos, J.; Getman, D.P.; Hockerman, S.L.; Li, M.; Mehta, P.; Munie, G.E.; Swearingen, C. alphaAlkyl-alpha-amino-beta-sulphone hydroxamates as potent MMP inhibitors that spare MMP-1. Bioorg. Med. Chem. Lett., 2001, 11, 2723-2725.
-
(2001)
Bioorg. Med. Chem. Lett
, vol.11
, pp. 2723-2725
-
-
Becker, D.P.1
Decrescenzo, G.2
Freskos, J.3
Getman, D.P.4
Hockerman, S.L.5
Li, M.6
Mehta, P.7
Munie, G.E.8
Swearingen, C.9
-
66
-
-
19344366798
-
Gelatinase-mediated migration and invasion of cancer cells
-
Björklund, M.; Koivunen, E. Gelatinase-mediated migration and invasion of cancer cells. Biochim. Biophys. Acta, 2005, 1755, 37-69.
-
(2005)
Biochim. Biophys. Acta
, vol.1755
, pp. 37-69
-
-
Björklund, M.1
Koivunen, E.2
-
67
-
-
47349084576
-
Progress in the development of matrix metalloproteinase inhibitors
-
Tu, G.; Xu, W.; Huang, H.; Li, S. Progress in the development of matrix metalloproteinase inhibitors. Curr. Med. Chem., 2008, 15, 1388-1395.
-
(2008)
Curr. Med. Chem
, vol.15
, pp. 1388-1395
-
-
Tu, G.1
Xu, W.2
Huang, H.3
Li, S.4
-
68
-
-
4444264198
-
In discussion of the inhibition of angiogenesis and its mechanism in
-
Science Publishing Company. Beijing
-
Feng, X.; Danqing, S.; Yongsu, Z. In discussion of the inhibition of angiogenesis and its mechanism in Progress of Anti-neoplasmdrugs and Chemotherapy. Science Publishing Company. Beijing, 2001; Vol. 10, p. 243.
-
(2001)
Progress of Anti-neoplasmdrugs and Chemotherapy
, vol.10
, pp. 243
-
-
Feng, X.1
Danqing, S.2
Yongsu, Z.3
-
69
-
-
4444250592
-
Design, synthesis, and activity of caffeoyl pyrrolidine derivatives as potential gelatinase inhibitors
-
Li, Y.L.; Xu, W.F. Design, synthesis, and activity of caffeoyl pyrrolidine derivatives as potential gelatinase inhibitors. Bioorg. Med. Chem., 2004, 12, 5171-5180.
-
(2004)
Bioorg. Med. Chem
, vol.12
, pp. 5171-5180
-
-
Li, Y.L.1
Xu, W.F.2
-
70
-
-
33645008011
-
Inhibitory effect of caffeic acid phenethyl ester on the growth of C6 glioma cells in vitro and in vivo
-
Kuo, H.C.; Kuo, W.H.; Lee, Y.J.; Lin, W.L.; Chou, F.P.; Tseng, T.H. Inhibitory effect of caffeic acid phenethyl ester on the growth of C6 glioma cells in vitro and in vivo. Cancer Lett., 2006, 234, 199-208.
-
(2006)
Cancer Lett
, vol.234
, pp. 199-208
-
-
Kuo, H.C.1
Kuo, W.H.2
Lee, Y.J.3
Lin, W.L.4
Chou, F.P.5
Tseng, T.H.6
-
71
-
-
11844260060
-
Chemistry and biological activities of caffeic acid derivatives from Salvia miltiorrhiza
-
Jiang, R.W.; Lau, K.M.; Hon, P.M.; Mak, T.C.; Woo, K.S.; Fung, K.P. Chemistry and biological activities of caffeic acid derivatives from Salvia miltiorrhiza. Curr. Med. Chem., 2005, 12, 237-246.
-
(2005)
Curr. Med. Chem
, vol.12
, pp. 237-246
-
-
Jiang, R.W.1
Lau, K.M.2
Hon, P.M.3
Mak, T.C.4
Woo, K.S.5
Fung, K.P.6
-
72
-
-
33750689843
-
Caffeoyl pyrrolidine derivative LY52 inhibits tumor invasion and metastasis via suppression of matrix metalloproteinase activity
-
Qu, X.; Yuan, Y.; Xu, W.; Chen, M.; Cui, S.; Meng, H.; Li, Y.; Makuuchi, M.; Nakata, M.; Tang, W. Caffeoyl pyrrolidine derivative LY52 inhibits tumor invasion and metastasis via suppression of matrix metalloproteinase activity. Anticancer Res., 2006, 26, 3573-3578.
-
(2006)
Anticancer Res
, vol.26
, pp. 3573-3578
-
-
Qu, X.1
Yuan, Y.2
Xu, W.3
Chen, M.4
Cui, S.5
Meng, H.6
Li, Y.7
Makuuchi, M.8
Nakata, M.9
Tang, W.10
-
73
-
-
34547734676
-
Using caffeoyl pyrrolidine derivative LY52, a potential inhibitor of matrix metalloproteinase-2, to suppress tumor invasion and metastasis
-
Qu, X.J.; Yuan, Y.X.; Tian, Z.G.; Xu, W.F.; Chen, M.H.; Cui, S.X.; Guo, Q.; Gai, R.; Makuuchi, M.; Nakata, M.; Tang, W. Using caffeoyl pyrrolidine derivative LY52, a potential inhibitor of matrix metalloproteinase-2, to suppress tumor invasion and metastasis. Int. J. Mol. Med., 2006, 18, 609-614.
-
(2006)
Int. J. Mol. Med
, vol.18
, pp. 609-614
-
-
Qu, X.J.1
Yuan, Y.X.2
Tian, Z.G.3
Xu, W.F.4
Chen, M.H.5
Cui, S.X.6
Guo, Q.7
Gai, R.8
Makuuchi, M.9
Nakata, M.10
Tang, W.11
-
74
-
-
39449129390
-
Inhibitory effects of matrix metalloproteinase (MMP) inhibitor LY52 on expression of MMP-2 and MMP-9 and invasive ability of human ovarian carcinoma cell line SKOV3
-
Yuan, Y.X.; Xu, W.F.; Liu, J.; Chen, M.H.; Meng, H.; Qu, X.J. Inhibitory effects of matrix metalloproteinase (MMP) inhibitor LY52 on expression of MMP-2 and MMP-9 and invasive ability of human ovarian carcinoma cell line SKOV3. Ai Zheng, 2006, 25, 663-670.
-
(2006)
Ai Zheng
, vol.25
, pp. 663-670
-
-
Yuan, Y.X.1
Xu, W.F.2
Liu, J.3
Chen, M.H.4
Meng, H.5
Qu, X.J.6
-
75
-
-
31044453202
-
Design, synthesis, and evaluation of novel galloyl pyrrolidine derivatives as potential anti-tumor agents
-
Li, X.; Li, Y.; Xu, W. Design, synthesis, and evaluation of novel galloyl pyrrolidine derivatives as potential anti-tumor agents. Bioorg. Med. Chem., 2006, 14, 1287-1293.
-
(2006)
Bioorg. Med. Chem
, vol.14
, pp. 1287-1293
-
-
Li, X.1
Li, Y.2
Xu, W.3
-
76
-
-
33750506919
-
Design, synthesis and preliminary evaluation of new cinnamoyl pyrrolidine derivatives as potent gelatinase inhibitors
-
Zhang, L.; Zhang, J.; Fang, H.; Wang, Q.; Xu, W. Design, synthesis and preliminary evaluation of new cinnamoyl pyrrolidine derivatives as potent gelatinase inhibitors. Bioorg. Med. Chem., 2006, 14, 8286-8294.
-
(2006)
Bioorg. Med. Chem
, vol.14
, pp. 8286-8294
-
-
Zhang, L.1
Zhang, J.2
Fang, H.3
Wang, Q.4
Xu, W.5
-
77
-
-
50349090567
-
Synthesis of new sulfonyl pyrrolidine derivatives as matrix metalloproteinase inhibitors
-
Cheng, X.C.; Wang, Q.; Fang, H.; Tang, W.; Xu, W.F. Synthesis of new sulfonyl pyrrolidine derivatives as matrix metalloproteinase inhibitors. Bioorg. Med. Chem., 2008, 16, 7932-7938.
-
(2008)
Bioorg. Med. Chem
, vol.16
, pp. 7932-7938
-
-
Cheng, X.C.1
Wang, Q.2
Fang, H.3
Tang, W.4
Xu, W.F.5
-
78
-
-
43749091066
-
Design, synthesis and evaluation of novel sulfonyl pyrrolidine derivatives as matrix metalloproteinase inhibitors
-
Cheng, X.C.; Wang, Q.; Fang, H.; Tang, W.; Xu, W.F. Design, synthesis and evaluation of novel sulfonyl pyrrolidine derivatives as matrix metalloproteinase inhibitors. Bioorg. Med. Chem., 2008, 16, 5398-5404.
-
(2008)
Bioorg. Med. Chem
, vol.16
, pp. 5398-5404
-
-
Cheng, X.C.1
Wang, Q.2
Fang, H.3
Tang, W.4
Xu, W.F.5
-
79
-
-
53149148170
-
Design, synthesis and preliminary evaluation of novel pyrrolidine derivatives as matrix metalloproteinase inhibitors
-
Cheng, X.C.; Wang, Q.; Fang, H.; Tang, W.; Xu, W.F. Design, synthesis and preliminary evaluation of novel pyrrolidine derivatives as matrix metalloproteinase inhibitors. Eur. J. Med. Chem., 2008, 43, 2130-2139.
-
(2008)
Eur. J. Med. Chem
, vol.43
, pp. 2130-2139
-
-
Cheng, X.C.1
Wang, Q.2
Fang, H.3
Tang, W.4
Xu, W.F.5
-
80
-
-
39449127018
-
Role of sulfonamide group in matrix metalloproteinase inhibitors
-
Cheng, X.C.; Wang, Q.; Fang, H.; Xu, W.F. Role of sulfonamide group in matrix metalloproteinase inhibitors. Curr. Med. Chem., 2008, 15, 368-373.
-
(2008)
Curr. Med. Chem
, vol.15
, pp. 368-373
-
-
Cheng, X.C.1
Wang, Q.2
Fang, H.3
Xu, W.F.4
-
81
-
-
0022376689
-
Production of actinonin, an inhibitor of aminopeptidase M, by actinomycetes
-
Umezawa, H.; Aoyagi, T.; Tanaka, T.; Suda, H.; Okuyama, A.; Naganawa, H.; Hamada, M.; Takeuchi, T. Production of actinonin, an inhibitor of aminopeptidase M, by actinomycetes. J. Antibiot. (Tokyo), 1985, 38, 1629-1630.
-
(1985)
J. Antibiot. (Tokyo)
, vol.38
, pp. 1629-1630
-
-
Umezawa, H.1
Aoyagi, T.2
Tanaka, T.3
Suda, H.4
Okuyama, A.5
Naganawa, H.6
Hamada, M.7
Takeuchi, T.8
-
82
-
-
28144451811
-
Combining in Silico tools and NMR data to validate protein-ligand structural models: Application to matrix metalloproteinases
-
Bertini, I.; Fragai, M.; Giachetti, A.; Luchinat, C.; Maletta, M.; Parigi, G.; Yeo, K.J. Combining in Silico tools and NMR data to validate protein-ligand structural models: application to matrix metalloproteinases. J. Med. Chem., 2005, 48, 7544-7559.
-
(2005)
J. Med. Chem
, vol.48
, pp. 7544-7559
-
-
Bertini, I.1
Fragai, M.2
Giachetti, A.3
Luchinat, C.4
Maletta, M.5
Parigi, G.6
Yeo, K.J.7
-
83
-
-
0025190250
-
Probestin, a new inhibitor of aminopeptidase N, produced by Streptomyces azureus MH663-2F6. I. Taxonomy, production, isolation, physico-chemical properties, and biological activities
-
Aoyagi, T.; Yoshida, S.; Nakamura, Y.; Shigihara, Y.; Hamada, M.; Takeuchi, T. Probestin, a new inhibitor of aminopeptidase N, produced by Streptomyces azureus MH663-2F6. I. Taxonomy, production, isolation, physico-chemical properties, and biological activities. J. Antibiot. (Tokyo), 1990, 43, 143-148.
-
(1990)
J. Antibiot. (Tokyo)
, vol.43
, pp. 143-148
-
-
Aoyagi, T.1
Yoshida, S.2
Nakamura, Y.3
Shigihara, Y.4
Hamada, M.5
Takeuchi, T.6
-
84
-
-
0030070283
-
MR-387A and B, new aminopeptidase N inhibitors, produced by Streptomyces neyagawaensis SL-387
-
Chung, M.C.; Chun, H.K.; Han, K.H.; Lee, H.J.; Lee, C.H.; Kho, Y.H. MR-387A and B, new aminopeptidase N inhibitors, produced by Streptomyces neyagawaensis SL-387. J. Antibiot. (Tokyo), 1996, 49, 99-102.
-
(1996)
J. Antibiot. (Tokyo)
, vol.49
, pp. 99-102
-
-
Chung, M.C.1
Chun, H.K.2
Han, K.H.3
Lee, H.J.4
Lee, C.H.5
Kho, Y.H.6
-
85
-
-
0035072854
-
Matrix metalloproteinase inhibitors: How can we optimize their development?
-
Hidalgo, M.; Eckhardt, S.G. Matrix metalloproteinase inhibitors: how can we optimize their development? Ann. Oncol., 2001, 12, 285-287.
-
(2001)
Ann. Oncol
, vol.12
, pp. 285-287
-
-
Hidalgo, M.1
Eckhardt, S.G.2
-
86
-
-
63849287732
-
Recent insights into the role of dipeptidyl aminopeptidase IV (DPIV) and aminopeptidase N (APN) families in immune functions
-
Ansorge, S.; Bank, U.; Heimburg, A.; Helmuth, M.; Koch, G.; Tadje, J.; Lendeckel, U.; Wolke, C.; Neubert, K.; Faust, J.; Fuchs, P.; Reinhold, D.; Thielitz, A.; Täger, M. Recent insights into the role of dipeptidyl aminopeptidase IV (DPIV) and aminopeptidase N (APN) families in immune functions. Clin. Chem. Lab Med., 2009, 47, 253-261.
-
(2009)
Clin. Chem. Lab Med
, vol.47
, pp. 253-261
-
-
Ansorge, S.1
Bank, U.2
Heimburg, A.3
Helmuth, M.4
Koch, G.5
Tadje, J.6
Lendeckel, U.7
Wolke, C.8
Neubert, K.9
Faust, J.10
Fuchs, P.11
Reinhold, D.12
Thielitz, A.13
Täger, M.14
-
87
-
-
58149384690
-
Aminopeptidase N (APN/CD13) as a target for anti-cancer agent design
-
Zhang, X.; Xu, W. Aminopeptidase N (APN/CD13) as a target for anti-cancer agent design. Curr. Med. Chem., 2008, 15, 2850-2865.
-
(2008)
Curr. Med. Chem
, vol.15
, pp. 2850-2865
-
-
Zhang, X.1
Xu, W.2
Aminopeptidase, N.3
|