Crystal structures of MMP-1 and -13 reveal the structural basis for selectivity of collagenase inhibitors

Nature Structural Biology

Volumn 6, Issue 3, 1999, Pages 217-221

  Lovejoy, B ^a   Welch, A R ^a   Carr, S ^a   Luong, C ^a   Broka, C ^a   Hendricks, R T ^a   Campbell, J A ^a   Walker, K A M ^a   Martin, R ^a   Van Wart, H ^a   Browner, M F ^a  

^a ROCHE BIOSCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [[[4 (4 CHLOROPHENOXY)PHENYL]SULFONYL]METHYL]TETRAHYDRO 2H PYRAN 4 CARBOHYDROXAMIC ACID; COLLAGENASE; COLLAGENASE 3; COLLAGENASE INHIBITOR; DIPHENYL ETHER DERIVATIVE; MATRIX METALLOPROTEINASE; RS 104966; RS 113456; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME INHIBITOR COMPLEX; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; COLLAGENASES; CRYSTALLOGRAPHY, X-RAY; HUMANS; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 13; PROTEASE INHIBITORS; PROTEIN STRUCTURE, SECONDARY;

EID: 0033048045     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/6657     Document Type: Article

References (28)