Expression of copper-related genes in response to copper load

American Journal of Clinical Nutrition

Volumn 88, Issue 3, 2008, Pages

  González, Mauricio ^a   Reyes Jara, Angélica ^a   Suazo, Miriam ^c   Jo, William J ^b   Vulpe, Chris ^b  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Institute of Nutrition and Food Technology ^*

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; TRACE ELEMENT;

CELL FUNCTION; CONFERENCE PAPER; COPPER METABOLISM; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; GENOME ANALYSIS; HOMEOSTASIS;

EUKARYOTA;

EID: 51749107035     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/88.3.830s     Document Type: Conference Paper

References (49)

1. DeFreitas J, Wintz H, Kim JH, et al. Yeast, a model organism for iron and copper metabolism studies. Biometals 2003;16:185-97.
2. Zhou B, Gitschier J. hCTR1: a human gene for copper uptake identified by complementation in yeast. Proc Natl Acad Sci U S A 1997;94:7481-6.
3. Vulpe CD, Packman S. Cellular copper transport. Annu Rev Nutr 1995;15:293-322.
4. Dancis A, Haile D, Yuan DS, Klausner RD. The Saccharomyces cerevisiae copper transport protein (Ctr1p). Biochemical characterization, regulation by copper, and physiologic role in copper uptake. J Biol Chem 1994;269:25660-7.
5. Pena MM, Puig S, Thiele DJ. Characterization of the Saccharomyces cerevisiae high affinity copper transporter Ctr3. J Biol Chem 2000;275:33244-51.
6. Yun CW, Bauler M, Moore RE, et al. The role of the FRE family of plasma membrane reductases in the uptake of siderophore-iron in Saccharomyces cerevisiae. J Biol Chem 2001;276:10218-23.
7. Puig S, Thiele DJ. Molecular mechanisms of copper uptake and distribution. Curr Opin Chem Biol 2002;6:171-80.
8. Armendariz AD, Gonzalez M, Loguinov AV, Vulpe CD. Gene expression profiling in chronic copper overload reveals upregulation of Prnp and App. Physiol Genomics 2004;20:45-54.
9. Armendariz AD, Olivares F, Pulgar R, et al. Gene expression profiling in wild-type and metallothionein mutant fibroblast cell lines. Biol Res 2006;39:125-42.
10. Muller P, van Bakel H, van de Sluis B, et al. Gene expression profiling of liver cells after copper overload in vivo and in vitro reveals new copper-regulated genes. J Biol Inorg Chem 2007;12:495-507.
11. Ohgami RS, Campagna DR, McDonald A, Fleming MD. The Steap proteins are metalloreductases. Blood 2006;108:1388-94.
12. Ruiz FH, Gonzalez M, Bodini M, et al. Cysteine 144 is a key residue in the copper reduction by the beta-amyloid precursor protein. J Neurochem 1999;73:1288-92.
13. Puig S, Lee J, Lau M, Thiele DJ. Biochemical and genetic analyses of yeast and human high affinity copper transporters suggest a conserved mechanism for copper uptake. J Biol Chem 2002;277:26021-30.
14. Arredondo M, Munoz P, Mura CV, Nunez MT. DMT1, a physiologically relevant apical Cu1+ transporter of intestinal cells. Am J Physiol Cell Physiol 2003;284:C1525-30.
15. Hamza I, Schaefer M, Klomp LW, Gitlin JD. Interaction of the copper chaperone HAH1 with the Wilson disease protein is essential for copper homeostasis. Proc Natl Acad Sci USA 1999;96:13363- 8.
16. Culotta VC, Klomp LW, Strain J, et al. The copper chaperone for superoxide dismutase. J Biol Chem 1997;272:23469-72.
17. Leary SC, Kaufman BA, Pellecchia G, et al. Human SCO1 and SCO2 have independent, cooperative functions in copper delivery to cytochrome c oxidase. Hum Mol Genet 2004;13:1839-48.
18. Freedman JH, Ciriolo MR, Peisach J. The role of glutathione in copper metabolism and toxicity. J Biol Chem 1989;264:5598-605.
19. Pena MM, Koch KA, Thiele DJ. Dynamic regulation of copper uptake and detoxification genes in Saccharomyces cerevisiae. Mol Cell Biol 1998;18:2514-23.
20. Labbe S, Zhu Z, Thiele DJ. Copper-specific transcriptional repression of yeast genes encoding critical components in the copper transport pathway. J Biol Chem 1997;272:15951-8.
21. De Freitas JM, Kim JH, Poynton H, et al. Exploratory and confirmatory gene expression profiling of mac1Delta. J Biol Chem 2004;279:4450-8.
22. van Bakel H, Strengman E, Wijmenga C, Holstege FC. Gene expression profiling and phenotype analyses of S. cerevisiae in response to changing copper reveals six genes with new roles in copper and iron metabolism. Physiol Genomics 2005;22:356-67.
23. Thiele DJ. ACE1 regulates expression of the Saccharomyces cerevisiae metallothionein gene. Mol Cell Biol 1988;8:2745-52.
24. Gross C, Kelleher M, Iyer VR, Brown PO, Winge DR. Identification of the copper regulon in Saccharomyces cerevisiae by DNA microarrays. J Biol Chem 2000;275:32310-6.
25. Rustici G, van Bakel H, Lackner DH, et al. Global transcriptional responses of fission and budding yeast to changes in copper and iron levels: a comparative study. Genome Biol 2007;8:R73.
26. Petris MJ, Smith K, Lee J, Thiele DJ. Copper-stimulated endocytosis and degradation of the human copper transporter, hCtr1. J Biol Chem 2003;278:9639-46.
27. Tapia L, Gonzalez-Aguero M, Cisternas MF, et al. Metallothionein is crucial for safe intracellular copper storage and cell survival at normal and supra-physiological exposure levels. Biochem J 2004;378:617-24.
28. Stockel J, Safar J, Wallace AC, et al. Prion protein selectively binds copper(II) ions. Biochemistry 1998;37:7185-93.
29. Varela-Nallar L, Toledo EM, Larrondo LF, et al. Induction of cellular prion protein gene expression by copper in neurons. Am J Physiol Cell Physiol 2006;290:C271-81.
30. Prohaska JR, Broderius M, Brokate B. Metallochaperone for Cu,Zn-superoxide dismutase (CCS) protein but not mRNA is higher in organs from copper-deficient mice and rats. Arch Biochem Biophys 2003;417:227-34.
31. Suazo M, Olivares F, Mendez MA, et al. CCS and SOD1 mRNA are reduced after copper supplementation in peripheral mononuclear cells of individuals with high serum ceruloplasmin concentration. J Nutr Biochem 2008;19:269-74.
32. Strand S, Hofmann WJ, Grambihler A, et al. Hepatic failure and liver cell damage in acute Wilson's disease involve CD95 (APO-1/Fas) mediated apoptosis. Nat Med 1998;4:588-93.
33. Samuele A, Mangiagalli A, Armentero MT, et al. Oxidative stress and pro-apoptotic conditions in a rodent model of Wilson's disease. Biochim Biophys Acta 2005;1741:325-30.
34. Coronado V, Nanji M, Cox DW. The Jackson toxic milk mouse as a model for copper loading. Mamm Genome 2001;12:793-5.
35. Buiakova OI, Xu J, Lutsenko S, et al. Null mutation of the murine ATP7B (Wilson disease) gene results in intracellular copper accumulation and late-onset hepatic nodular transformation. Hum Mol Genet 1999;8:1665-71.
36. Wu J, Forbes JR, Chen HS, Cox DW. The LEC rat has a deletion in the copper transporting ATPase gene homologous to the Wilson disease gene. Nat Genet 1994;7:541-5.
37. Huster D, Purnat TD, Burkhead JL, et al. High copper selectively alters lipid metabolism and cell cycle machinery in the mouse model of Wilson disease. J Biol Chem 2007;282:8343-55.
38. Tao TY, Liu F, Klomp L, et al. The copper toxicosis gene product Murr1 directly interacts with the Wilson disease protein. J Biol Chem 2003;278:41593-6.
39. Klomp AE, van de Sluis B, Klomp LW, Wijmenga C. The ubiquitously expressed MURR1 protein is absent in canine copper toxicosis. J Hepatol 2003;39:703-9.
40. de Bie P, van de Sluis B, Burstein E, et al. Distinct Wilson's disease mutations in ATP7 Bare associated with enhanced binding to COMMD1 and reduced stability of ATP7B. Gastroenterology 2007;133:1316 -26.
41. Maine GN, Mao X, Komarck CM, Burstein E. COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase. Embo J 2007;26:436-47.
42. Roberts EA, Lau CH, Silveira TR, Yang S. Developmental expression of Commd1 in the liver of the Jackson toxic milk mouse. Biochem Biophys Res Commun 2007;363:921-5.
43. Davis AK, Hildebrand M, Palenik B. Gene expression induced by copper stress in the diatom Thalassiosira pseudonana. Eukaryot Cell 2006;5:1157-68.
44. Teitzel GM, Geddie A, De Long SK, et al. Survival and growth in the presence of elevated copper: transcriptional profiling of copper-stressed Pseudomonas aeruginosa. J Bacteriol 2006;188:7242-56.
45. Jo WJ, Loguinov A, Chang M, et al. Identification of genes involved in the toxic response of Saccharomyces cerevisiae against iron and copper overload by parallel analysis of deletion mutants. Toxicol Sci 2008;101:140-51.
46. Yepiskoposyan H, Egli D, Fergestad T, et al. Transcriptome response to heavy metal stress in Drosophila reveals a new zinc transporter that confers resistance to zinc. Nucleic Acid Res 2006;34:4866-77.
47. Norgate M, Southon A, Zou S, et al. Copper homeostasis gene discovery in Drosophila melanogaster. Biometals 2007;20:683-97.
48. Egli D, Selvaraj A, Yepiskoposyan H, et al. Knockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis. EMBO J 2003;22:100-8.
49. Simpson DM, Mobasheri A, Haywood S, Beynon RJ. A proteomics study of the response of North Ronaldsay sheep to copper challenge. BMC Vet Res 2006;2:36.