-
1
-
-
9244251125
-
Cell-cycle checkpoints and cancer
-
Kastan MB, Bartek J. Cell-cycle checkpoints and cancer. Nature 2004;432:316-23.
-
(2004)
Nature
, vol.432
, pp. 316-323
-
-
Kastan, M.B.1
Bartek, J.2
-
2
-
-
34247333444
-
The spindle-assembly checkpoint in space and time
-
Musacchio A, Salmon ED. The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol 2007;8:379-93.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 379-393
-
-
Musacchio, A.1
Salmon, E.D.2
-
3
-
-
33751182302
-
The spindle checkpoint
-
May KM, Hardwick KG. The spindle checkpoint. J Cell Sci 2006;119:4139-42.
-
(2006)
J Cell Sci
, vol.119
, pp. 4139-4142
-
-
May, K.M.1
Hardwick, K.G.2
-
4
-
-
27544515607
-
The mitotic checkpoint in cancer and aging: What have mice taught us?
-
Baker DJ, Chen J, van Deursen JM. The mitotic checkpoint in cancer and aging: what have mice taught us? Curr Opin Cell Biol 2005;17:583-9.
-
(2005)
Curr Opin Cell Biol
, vol.17
, pp. 583-589
-
-
Baker, D.J.1
Chen, J.2
Van Deursen, J.M.3
-
5
-
-
25844475838
-
On the road to cancer: Aneuploidy and the mitotic checkpoint
-
Kops GJ, Weaver BA, Cleveland DW. On the road to cancer: aneuploidy and the mitotic checkpoint. Nat Rev Cancer 2005;5:773-85.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 773-785
-
-
Kops, G.J.1
Weaver, B.A.2
Cleveland, D.W.3
-
6
-
-
1842486792
-
The spindle checkpoint, aneuploidy, and cancer
-
Bharadwaj R, Yu H. The spindle checkpoint, aneuploidy, and cancer. Oncogene 2004;23:2016-27.
-
(2004)
Oncogene
, vol.23
, pp. 2016-2027
-
-
Bharadwaj, R.1
Yu, H.2
-
8
-
-
0035803404
-
Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores
-
Fraschini R, Beretta A, Sironi L, Musacchio A, Lucchini G, Piatti S. Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores. EMBO J 2001;20:6648-59.
-
(2001)
EMBO J
, vol.20
, pp. 6648-6659
-
-
Fraschini, R.1
Beretta, A.2
Sironi, L.3
Musacchio, A.4
Lucchini, G.5
Piatti, S.6
-
9
-
-
0035802122
-
Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2
-
DOI 10.1083/jcb.200102093
-
Sudakin V, Chan GK, Yen TJ. Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2. J Cell Biol 2001;154:925-36. (Pubitemid 34286173)
-
(2001)
Journal of Cell Biology
, vol.154
, Issue.5
, pp. 925-936
-
-
Sudakin, V.1
Chan, G.K.T.2
Yen, T.J.3
-
10
-
-
0035854379
-
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint
-
DOI 10.1016/S0092-8674(01)00410-X
-
Abrieu A, Magnaghi-Jaulin L, Kahana JA, Peter M, Castro A, Vigneron S, Lorca T, Cleveland DW, Labbé JC. Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint. Cell 2001;106:83-93. (Pubitemid 32709960)
-
(2001)
Cell
, vol.106
, Issue.1
, pp. 83-93
-
-
Abrieu, A.1
Magnaghi-Jaulin, L.2
Kahana, J.A.3
Peter, M.4
Castro, A.5
Vigneron, S.6
Lorca, T.7
Cleveland, D.W.8
Labbe, J.-C.9
-
11
-
-
34447094967
-
A census of mitotic cancer genes: New insights into tumor cell biology and cancer therapy
-
DOI 10.1093/carcin/bgm019
-
Perez de Castro I, de Carcer G, Malumbres M. A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy. Carcinogenesis 2007;28:899-912. (Pubitemid 47072171)
-
(2007)
Carcinogenesis
, vol.28
, Issue.5
, pp. 899-912
-
-
Perez De Castro, I.1
De Carcer, G.2
Malumbres, M.3
-
12
-
-
0032101688
-
Localization of Mad2 to kinetochores depends on microtubule attachment, not tension
-
Waters JC, Chen RH, Murray AW, Salmon ED. Localization of Mad2 to kinetochores depends on microtubule attachment, not tension. J Cell Biol 1998;141:1181-91.
-
(1998)
J Cell Biol
, vol.141
, pp. 1181-1191
-
-
Waters, J.C.1
Chen, R.H.2
Murray, A.W.3
Salmon, E.D.4
-
13
-
-
0035878126
-
Inhibition of Cdh1-APC by the MAD2L2: A novel mechanism for regulating Cdh1
-
Pfleger CM, Salic A, Lee E, Kirschner MW. Inhibition of Cdh1-APC by the MAD2L2: a novel mechanism for regulating Cdh1. Genes Dev 2001;15:1759-64.
-
(2001)
Genes Dev
, vol.15
, pp. 1759-1764
-
-
Pfleger, C.M.1
Salic, A.2
Lee, E.3
Kirschner, M.W.4
-
14
-
-
0034952728
-
Identification of an overlapping binding domain on Cdc20 for Mad2 and anaphase-promoting complex: Model for spindle checkpoint regulation
-
DOI 10.1128/MCB.21.15.5190-5199.2001
-
Zhang Y, Lees E. Identification of an overlapping binding domain on CDC20 for Mad2 and anaphase-promoting complex: model for spindle checkpoint regulation. Mol Cell Biol 2001;21:5190-9. (Pubitemid 32656414)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.15
, pp. 5190-5199
-
-
Zhang, Y.1
Lees, E.2
-
15
-
-
0035999976
-
Spindle checkpoint requires Mad1-bound and Mad1-free Mad2
-
DOI 10.1091/mbc.02-01-0003
-
Chung E, Chen RH. Spindle checkpoint requires Mad1-bound and Mad1-free Mad2. Mol Biol Cell 2002;13:1501-11. (Pubitemid 34522634)
-
(2002)
Molecular Biology of the Cell
, vol.13
, Issue.5
, pp. 1501-1511
-
-
Chung, E.1
Chen, R.-H.2
-
16
-
-
0037093326
-
Crystal structure of the tetrameric MAD1-MAD2 core complex: Implications of a 'safety belt' binding mechanism for the spindle checkpoint
-
Sironi L, Mapelli M, Knapp S, Antoni AD, Jeang K, Musacchio A. Crystal structure of the tetrameric MAD1-MAD2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint. EMBO J 2002;21:2496-506.
-
(2002)
EMBO J
, vol.21
, pp. 2496-2506
-
-
Sironi, L.1
Mapelli, M.2
Knapp, S.3
Antoni, A.D.4
Jeang, K.5
Musacchio, A.6
-
17
-
-
33646092999
-
Structural activation of Mad2 in the mitotic spindle checkpoint: The two-state Mad2 model versus the Mad2 template model
-
Yu H. Structural activation of Mad2 in the mitotic spindle checkpoint: the two-state Mad2 model versus the Mad2 template model. J Cell Biol 2006;173:153-7.
-
(2006)
J Cell Biol
, vol.173
, pp. 153-157
-
-
Yu, H.1
-
18
-
-
17644394240
-
How do so few control so many?
-
Nasmyth K. How do so few control so many? Cell 2005;120:739-46.
-
(2005)
Cell
, vol.120
, pp. 739-746
-
-
Nasmyth, K.1
-
19
-
-
2942567685
-
Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint
-
Kops GJ, Foltz DR, Cleveland DW. Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint. Proc Natl Acad Sci U S A 2004;101:8699-704.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 8699-8704
-
-
Kops, G.J.1
Foltz, D.R.2
Cleveland, D.W.3
-
20
-
-
36049044125
-
The Mad2 Conformational Dimer: Structure and Implications for the Spindle Assembly Checkpoint
-
DOI 10.1016/j.cell.2007.08.049, PII S0092867407012007
-
Mapelli M, Massimiliano L, Santaguida S, Musacchio A. The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint. Cell 2007;131:730-43. (Pubitemid 350087197)
-
(2007)
Cell
, vol.131
, Issue.4
, pp. 730-743
-
-
Mapelli, M.1
Massimiliano, L.2
Santaguida, S.3
Musacchio, A.4
-
21
-
-
0037163116
-
Characterization of regions in hsMAD1 needed for binding hsMAD2
-
Iwanaga Y, Kasai T, Kibler K, Jeang KT. Characterization of regions in hsMAD1 needed for binding hsMAD2. J Biol Chem 2002;277:31005-13.
-
(2002)
J Biol Chem
, vol.277
, pp. 31005-31013
-
-
Iwanaga, Y.1
Kasai, T.2
Kibler, K.3
Jeang, K.T.4
-
22
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005;55:74-108.
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
23
-
-
35748944102
-
Centrosome abnormalities in non-small cell lung cancer: Correlations with DNA aneuploidy and expression of cell cycle regulatory proteins
-
DOI 10.1016/j.prp.2007.08.004, PII S0344033807001719
-
Jung CK, Jung JH, Lee KY, Kang CS, Kim M, Ko YH, Oh CS. Centrosome abnormalities in non-small cell lung cancer: correlations with DNA aneuploidy and expression of cell cycle regulatory proteins. Pathol Res Pract 2007;203:839-47. (Pubitemid 350048630)
-
(2007)
Pathology Research and Practice
, vol.203
, Issue.12
, pp. 839-847
-
-
Jung, C.K.1
Jung, J.H.2
Lee, K.Y.3
Kang, C.S.4
Kim, M.5
Ko, Y.H.6
Oh, C.S.7
-
24
-
-
0030825508
-
Chromosomal imbalance maps of malignant solid tumors: A cytogenetic survey of 3185 neoplasms
-
Mertens F, Johansson B, Hoglund M, Mitelman F. Chromosomal imbalance maps of malignant solid tumors: a cytogenetic survey of 3185 neoplasms. Cancer Res 1997;57:2765-80. (Pubitemid 27283792)
-
(1997)
Cancer Research
, vol.57
, Issue.13
, pp. 2765-2780
-
-
Mertens, F.1
Johansson, B.2
Hoglund, M.3
Mitelman, F.4
-
25
-
-
0034020389
-
Aneuploidy of chromosome 7 can be detected in invasive lung cancer and associated premalignant lesions of the lung by fluorescence in situ hybridisation
-
DOI 10.1016/S0169-5002(00)00097-0, PII S0169500200000970
-
Zojer N, Dekan G, Ackermann J, Fiegl M, Kaufmann H, Drach J, Huber H. Aneuploidy of chromosome 7 can be detected in invasive lung cancer and associated premalignant lesions of the lung by fluorescence in situ hybridisation. Lung Cancer 2000;28:225-35. (Pubitemid 30254230)
-
(2000)
Lung Cancer
, vol.28
, Issue.3
, pp. 225-235
-
-
Zojer, N.1
Dekan, G.2
Ackermann, J.3
Fiegl, M.4
Kaufmann, H.5
Drach, J.6
Huber, H.7
-
26
-
-
0035816267
-
Aneuploidy and prognosis of non-small-cell lung cancer: A meta-analysis of published data
-
DOI 10.1054/bjoc.2001.1892
-
Choma D, Daures JP, Quantin X, Pujol JL. Aneuploidy and prognosis of non-small-cell lung cancer: a meta-analysis of published data. Br J Cancer 2001;85:14-22. (Pubitemid 32695710)
-
(2001)
British Journal of Cancer
, vol.85
, Issue.1
, pp. 14-22
-
-
Choma, D.1
Daures, J.-P.2
Quantin, X.3
Pujol, J.L.4
-
27
-
-
0142119289
-
Epidermal growth factor receptor in non-small-cell lung carcinomas: Correlation between gene copy number and protein expression and impact on prognosis
-
DOI 10.1200/JCO.2003.11.069
-
Hirsch FR, Varella-Garcia M, Bunn PA Jr, Di Maria MV, Veve R, Bremmes RM, Barón AE, Zeng C, Franklin WA. Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis. J Clin Oncol 2003;21:3798-807. (Pubitemid 46606235)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.20
, pp. 3798-3807
-
-
Hirsch, F.R.1
Varella-Garcia, M.2
Bunn Jr., P.A.3
Di Maria, M.V.4
Veve, R.5
Bremnes, R.M.6
Baron, A.E.7
Zeng, C.8
Franklin, W.A.9
-
28
-
-
33746502729
-
Adenosine diphosphate ribosyl transferase and x-ray repair cross-complementing 1 polymorphisms in gastric cardia cancer
-
Miao X, Zhang X, Zhang L, Guo Y, Hao B, Tan W, He F, Lin D. Adenosine diphosphate ribosyl transferase and x-ray repair cross-complementing 1 polymorphisms in gastric cardia cancer. Gastroenterology 2006;131:420-7.
-
(2006)
Gastroenterology
, vol.131
, pp. 420-427
-
-
Miao, X.1
Zhang, X.2
Zhang, L.3
Guo, Y.4
Hao, B.5
Tan, W.6
He, F.7
Lin, D.8
-
29
-
-
0030920202
-
Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro
-
Vasquez RJ, Howell B, Yvon AM, Wadsworth P, Cassimeris L. Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro. Mol Biol Cell 1997;8:973-85.
-
(1997)
Mol Biol Cell
, vol.8
, pp. 973-985
-
-
Vasquez, R.J.1
Howell, B.2
Yvon, A.M.3
Wadsworth, P.4
Cassimeris, L.5
-
30
-
-
69549123990
-
Functional FEN1 polymorphisms are associated with DNA damage levels and lung cancer risk
-
Yang M, Guo H, Wu C, He Y, Yu D, Zhou L, Wang F, Xu J, Tan W, Wang G, Shen B, Yuan J, Wu T, Lin D. Functional FEN1 polymorphisms are associated with DNA damage levels and lung cancer risk. Hum Mutat 2009;30:1320-8.
-
(2009)
Hum Mutat
, vol.30
, pp. 1320-1328
-
-
Yang, M.1
Guo, H.2
Wu, C.3
He, Y.4
Yu, D.5
Zhou, L.6
Wang, F.7
Xu, J.8
Tan, W.9
Wang, G.10
Shen, B.11
Yuan, J.12
Wu, T.13
Lin, D.14
-
31
-
-
13444306156
-
Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer
-
Zhang X, Miao X, Liang G, Hao B, Wang Y, Tan W, Li Y, Guo Y, He F, Wei Q, Lin D. Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer. Cancer Res 2005;65:722-6.
-
(2005)
Cancer Res
, vol.65
, pp. 722-726
-
-
Zhang, X.1
Miao, X.2
Liang, G.3
Hao, B.4
Wang, Y.5
Tan, W.6
Li, Y.7
Guo, Y.8
He, F.9
Wei, Q.10
Lin, D.11
-
32
-
-
0034968482
-
Mutations in the mitotic check point gene, MAD1L1, in human cancers
-
Tsukasaki K, Miller CW, Greenspun E, Eshaghian S, Kawabata H, Fujimoto T, Tomonaga M, Sawyers C, Said JW, Koeffler HP. Mutations in the mitotic check point gene, MAD1L1, in human cancers. Oncogene 2001;20:3301-5.
-
(2001)
Oncogene
, vol.20
, pp. 3301-3305
-
-
Tsukasaki, K.1
Miller, C.W.2
Greenspun, E.3
Eshaghian, S.4
Kawabata, H.5
Fujimoto, T.6
Tomonaga, M.7
Sawyers, C.8
Said, J.W.9
Koeffler, H.P.10
-
33
-
-
25844499131
-
Frequent mutations of human Mad2, but not Bub1, in gastric cancers cause defective mitotic spindle checkpoint
-
Kim HS, Park KH, Kim SA, Wen J, Park SW, Park B, Gham CW, Hyung WJ, Noh SH, Kim HK, Song SY. Frequent mutations of human Mad2, but not Bub1, in gastric cancers cause defective mitotic spindle checkpoint. Mutat Res 2005;578:187-201.
-
(2005)
Mutat Res
, vol.578
, pp. 187-201
-
-
Kim, H.S.1
Park, K.H.2
Kim, S.A.3
Wen, J.4
Park, S.W.5
Park, B.6
Gham, C.W.7
Hyung, W.J.8
Noh, S.H.9
Kim, H.K.10
Song, S.Y.11
-
34
-
-
13444288299
-
The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint
-
De Antoni A, Pearson CG, Cimini D, Canman JC, Sala V, Nezi L, Mapelli M, Sironi L, Faretta M, Salmon ED, Musacchio A. The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint. Curr Biol 2005;15:214-25.
-
(2005)
Curr Biol
, vol.15
, pp. 214-225
-
-
De Antoni, A.1
Pearson, C.G.2
Cimini, D.3
Canman, J.C.4
Sala, V.5
Nezi, L.6
Mapelli, M.7
Sironi, L.8
Faretta, M.9
Salmon, E.D.10
Musacchio, A.11
-
35
-
-
0035890057
-
Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint
-
Sironi L, Melixetian M, Faretta M, Prosperini E, Helin K, Musacchio A. Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint. EMBO J 2001;20:6371-82.
-
(2001)
EMBO J
, vol.20
, pp. 6371-6382
-
-
Sironi, L.1
Melixetian, M.2
Faretta, M.3
Prosperini, E.4
Helin, K.5
Musacchio, A.6
-
36
-
-
0036161468
-
The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20
-
Luo X, Tang Z, Rizo J, Yu H. The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20. Mol Cell 2002;9:59-71.
-
(2002)
Mol Cell
, vol.9
, pp. 59-71
-
-
Luo, X.1
Tang, Z.2
Rizo, J.3
Yu, H.4
-
37
-
-
33645315214
-
comet
-
comet. EMBO J 2006;25:1273-84.
-
(2006)
EMBO J
, vol.25
, pp. 1273-1284
-
-
Mapelli, M.1
Filipp, F.V.2
Rancati, G.3
Massimiliano, L.4
Nezi, L.5
Stier, G.6
Hagan, R.S.7
Confalonieri, S.8
Piatti, S.9
Sattler, M.10
Musacchio, A.11
-
38
-
-
1842533070
-
Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells
-
Michel L, Diaz-Rodriguez E, Narayan G, Hernando E, Murty VV, Benezra R. Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells. Proc Natl Acad Sci U S A 2004;101:4459-64.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 4459-4464
-
-
Michel, L.1
Diaz-Rodriguez, E.2
Narayan, G.3
Hernando, E.4
Murty, V.V.5
Benezra, R.6
-
39
-
-
34447095664
-
Breast cancer risk associated with genotypic polymorphism of the mitotic checkpoint genes: A multigenic study on cancer susceptibility
-
Lo YL, Yu JC, Chen ST, Hsu GC, Mau YC, Yang SL, Wu PE, Shen CY. Breast cancer risk associated with genotypic polymorphism of the mitotic checkpoint genes: a multigenic study on cancer susceptibility. Carcinogenesis 2007;28:1079-86.
-
(2007)
Carcinogenesis
, vol.28
, pp. 1079-1086
-
-
Lo, Y.L.1
Yu, J.C.2
Chen, S.T.3
Hsu, G.C.4
Mau, Y.C.5
Yang, S.L.6
Wu, P.E.7
Shen, C.Y.8
-
40
-
-
35748941668
-
Genetic variation in the major mitotic checkpoint genes does not affect familial breast cancer risk
-
Vaclavicek A, Bermejo JL, Wappenschmidt B, Meindl A, Sutter C, Schmutzler RK, Kiechle M, Bugert P, Burwinkel B, Bartram CR, Hemminki K, Försti A. Genetic variation in the major mitotic checkpoint genes does not affect familial breast cancer risk. Breast Cancer Res Treat 2007;106:205-13.
-
(2007)
Breast Cancer Res Treat
, vol.106
, pp. 205-213
-
-
Vaclavicek, A.1
Bermejo, J.L.2
Wappenschmidt, B.3
Meindl, A.4
Sutter, C.5
Schmutzler, R.K.6
Kiechle, M.7
Bugert, P.8
Burwinkel, B.9
Bartram, C.R.10
Hemminki, K.11
Försti, A.12
|