메뉴 건너뛰기




Volumn 47, Issue 9, 2010, Pages 616-622

Functional evaluation of missense variations in the human MAD1L1 and MAD2L1 genes and their impact on susceptibility to lung cancer

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; HISTIDINE; LEUCINE; METHIONINE; MITOTIC ARREST DEFICIENT LIKE 1 PROTEIN; MITOTIC ARREST DEFICIENT LIKE 2 PROTEIN; NOCODAZOLE; ONCOPROTEIN; PROTEIN MAD1; PROTEIN MAD2; UNCLASSIFIED DRUG;

EID: 77956109562     PISSN: 00222593     EISSN: 14686244     Source Type: Journal    
DOI: 10.1136/jmg.2009.074252     Document Type: Article
Times cited : (41)

References (40)
  • 1
    • 9244251125 scopus 로고    scopus 로고
    • Cell-cycle checkpoints and cancer
    • Kastan MB, Bartek J. Cell-cycle checkpoints and cancer. Nature 2004;432:316-23.
    • (2004) Nature , vol.432 , pp. 316-323
    • Kastan, M.B.1    Bartek, J.2
  • 2
    • 34247333444 scopus 로고    scopus 로고
    • The spindle-assembly checkpoint in space and time
    • Musacchio A, Salmon ED. The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol 2007;8:379-93.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 379-393
    • Musacchio, A.1    Salmon, E.D.2
  • 3
    • 33751182302 scopus 로고    scopus 로고
    • The spindle checkpoint
    • May KM, Hardwick KG. The spindle checkpoint. J Cell Sci 2006;119:4139-42.
    • (2006) J Cell Sci , vol.119 , pp. 4139-4142
    • May, K.M.1    Hardwick, K.G.2
  • 4
    • 27544515607 scopus 로고    scopus 로고
    • The mitotic checkpoint in cancer and aging: What have mice taught us?
    • Baker DJ, Chen J, van Deursen JM. The mitotic checkpoint in cancer and aging: what have mice taught us? Curr Opin Cell Biol 2005;17:583-9.
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 583-589
    • Baker, D.J.1    Chen, J.2    Van Deursen, J.M.3
  • 5
    • 25844475838 scopus 로고    scopus 로고
    • On the road to cancer: Aneuploidy and the mitotic checkpoint
    • Kops GJ, Weaver BA, Cleveland DW. On the road to cancer: aneuploidy and the mitotic checkpoint. Nat Rev Cancer 2005;5:773-85.
    • (2005) Nat Rev Cancer , vol.5 , pp. 773-785
    • Kops, G.J.1    Weaver, B.A.2    Cleveland, D.W.3
  • 6
    • 1842486792 scopus 로고    scopus 로고
    • The spindle checkpoint, aneuploidy, and cancer
    • Bharadwaj R, Yu H. The spindle checkpoint, aneuploidy, and cancer. Oncogene 2004;23:2016-27.
    • (2004) Oncogene , vol.23 , pp. 2016-2027
    • Bharadwaj, R.1    Yu, H.2
  • 8
    • 0035803404 scopus 로고    scopus 로고
    • Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores
    • Fraschini R, Beretta A, Sironi L, Musacchio A, Lucchini G, Piatti S. Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores. EMBO J 2001;20:6648-59.
    • (2001) EMBO J , vol.20 , pp. 6648-6659
    • Fraschini, R.1    Beretta, A.2    Sironi, L.3    Musacchio, A.4    Lucchini, G.5    Piatti, S.6
  • 9
    • 0035802122 scopus 로고    scopus 로고
    • Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2
    • DOI 10.1083/jcb.200102093
    • Sudakin V, Chan GK, Yen TJ. Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2. J Cell Biol 2001;154:925-36. (Pubitemid 34286173)
    • (2001) Journal of Cell Biology , vol.154 , Issue.5 , pp. 925-936
    • Sudakin, V.1    Chan, G.K.T.2    Yen, T.J.3
  • 11
    • 34447094967 scopus 로고    scopus 로고
    • A census of mitotic cancer genes: New insights into tumor cell biology and cancer therapy
    • DOI 10.1093/carcin/bgm019
    • Perez de Castro I, de Carcer G, Malumbres M. A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy. Carcinogenesis 2007;28:899-912. (Pubitemid 47072171)
    • (2007) Carcinogenesis , vol.28 , Issue.5 , pp. 899-912
    • Perez De Castro, I.1    De Carcer, G.2    Malumbres, M.3
  • 12
    • 0032101688 scopus 로고    scopus 로고
    • Localization of Mad2 to kinetochores depends on microtubule attachment, not tension
    • Waters JC, Chen RH, Murray AW, Salmon ED. Localization of Mad2 to kinetochores depends on microtubule attachment, not tension. J Cell Biol 1998;141:1181-91.
    • (1998) J Cell Biol , vol.141 , pp. 1181-1191
    • Waters, J.C.1    Chen, R.H.2    Murray, A.W.3    Salmon, E.D.4
  • 13
    • 0035878126 scopus 로고    scopus 로고
    • Inhibition of Cdh1-APC by the MAD2L2: A novel mechanism for regulating Cdh1
    • Pfleger CM, Salic A, Lee E, Kirschner MW. Inhibition of Cdh1-APC by the MAD2L2: a novel mechanism for regulating Cdh1. Genes Dev 2001;15:1759-64.
    • (2001) Genes Dev , vol.15 , pp. 1759-1764
    • Pfleger, C.M.1    Salic, A.2    Lee, E.3    Kirschner, M.W.4
  • 14
    • 0034952728 scopus 로고    scopus 로고
    • Identification of an overlapping binding domain on Cdc20 for Mad2 and anaphase-promoting complex: Model for spindle checkpoint regulation
    • DOI 10.1128/MCB.21.15.5190-5199.2001
    • Zhang Y, Lees E. Identification of an overlapping binding domain on CDC20 for Mad2 and anaphase-promoting complex: model for spindle checkpoint regulation. Mol Cell Biol 2001;21:5190-9. (Pubitemid 32656414)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.15 , pp. 5190-5199
    • Zhang, Y.1    Lees, E.2
  • 15
    • 0035999976 scopus 로고    scopus 로고
    • Spindle checkpoint requires Mad1-bound and Mad1-free Mad2
    • DOI 10.1091/mbc.02-01-0003
    • Chung E, Chen RH. Spindle checkpoint requires Mad1-bound and Mad1-free Mad2. Mol Biol Cell 2002;13:1501-11. (Pubitemid 34522634)
    • (2002) Molecular Biology of the Cell , vol.13 , Issue.5 , pp. 1501-1511
    • Chung, E.1    Chen, R.-H.2
  • 16
    • 0037093326 scopus 로고    scopus 로고
    • Crystal structure of the tetrameric MAD1-MAD2 core complex: Implications of a 'safety belt' binding mechanism for the spindle checkpoint
    • Sironi L, Mapelli M, Knapp S, Antoni AD, Jeang K, Musacchio A. Crystal structure of the tetrameric MAD1-MAD2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint. EMBO J 2002;21:2496-506.
    • (2002) EMBO J , vol.21 , pp. 2496-2506
    • Sironi, L.1    Mapelli, M.2    Knapp, S.3    Antoni, A.D.4    Jeang, K.5    Musacchio, A.6
  • 17
    • 33646092999 scopus 로고    scopus 로고
    • Structural activation of Mad2 in the mitotic spindle checkpoint: The two-state Mad2 model versus the Mad2 template model
    • Yu H. Structural activation of Mad2 in the mitotic spindle checkpoint: the two-state Mad2 model versus the Mad2 template model. J Cell Biol 2006;173:153-7.
    • (2006) J Cell Biol , vol.173 , pp. 153-157
    • Yu, H.1
  • 18
    • 17644394240 scopus 로고    scopus 로고
    • How do so few control so many?
    • Nasmyth K. How do so few control so many? Cell 2005;120:739-46.
    • (2005) Cell , vol.120 , pp. 739-746
    • Nasmyth, K.1
  • 19
    • 2942567685 scopus 로고    scopus 로고
    • Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint
    • Kops GJ, Foltz DR, Cleveland DW. Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint. Proc Natl Acad Sci U S A 2004;101:8699-704.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 8699-8704
    • Kops, G.J.1    Foltz, D.R.2    Cleveland, D.W.3
  • 20
    • 36049044125 scopus 로고    scopus 로고
    • The Mad2 Conformational Dimer: Structure and Implications for the Spindle Assembly Checkpoint
    • DOI 10.1016/j.cell.2007.08.049, PII S0092867407012007
    • Mapelli M, Massimiliano L, Santaguida S, Musacchio A. The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint. Cell 2007;131:730-43. (Pubitemid 350087197)
    • (2007) Cell , vol.131 , Issue.4 , pp. 730-743
    • Mapelli, M.1    Massimiliano, L.2    Santaguida, S.3    Musacchio, A.4
  • 21
    • 0037163116 scopus 로고    scopus 로고
    • Characterization of regions in hsMAD1 needed for binding hsMAD2
    • Iwanaga Y, Kasai T, Kibler K, Jeang KT. Characterization of regions in hsMAD1 needed for binding hsMAD2. J Biol Chem 2002;277:31005-13.
    • (2002) J Biol Chem , vol.277 , pp. 31005-31013
    • Iwanaga, Y.1    Kasai, T.2    Kibler, K.3    Jeang, K.T.4
  • 23
    • 35748944102 scopus 로고    scopus 로고
    • Centrosome abnormalities in non-small cell lung cancer: Correlations with DNA aneuploidy and expression of cell cycle regulatory proteins
    • DOI 10.1016/j.prp.2007.08.004, PII S0344033807001719
    • Jung CK, Jung JH, Lee KY, Kang CS, Kim M, Ko YH, Oh CS. Centrosome abnormalities in non-small cell lung cancer: correlations with DNA aneuploidy and expression of cell cycle regulatory proteins. Pathol Res Pract 2007;203:839-47. (Pubitemid 350048630)
    • (2007) Pathology Research and Practice , vol.203 , Issue.12 , pp. 839-847
    • Jung, C.K.1    Jung, J.H.2    Lee, K.Y.3    Kang, C.S.4    Kim, M.5    Ko, Y.H.6    Oh, C.S.7
  • 24
    • 0030825508 scopus 로고    scopus 로고
    • Chromosomal imbalance maps of malignant solid tumors: A cytogenetic survey of 3185 neoplasms
    • Mertens F, Johansson B, Hoglund M, Mitelman F. Chromosomal imbalance maps of malignant solid tumors: a cytogenetic survey of 3185 neoplasms. Cancer Res 1997;57:2765-80. (Pubitemid 27283792)
    • (1997) Cancer Research , vol.57 , Issue.13 , pp. 2765-2780
    • Mertens, F.1    Johansson, B.2    Hoglund, M.3    Mitelman, F.4
  • 25
    • 0034020389 scopus 로고    scopus 로고
    • Aneuploidy of chromosome 7 can be detected in invasive lung cancer and associated premalignant lesions of the lung by fluorescence in situ hybridisation
    • DOI 10.1016/S0169-5002(00)00097-0, PII S0169500200000970
    • Zojer N, Dekan G, Ackermann J, Fiegl M, Kaufmann H, Drach J, Huber H. Aneuploidy of chromosome 7 can be detected in invasive lung cancer and associated premalignant lesions of the lung by fluorescence in situ hybridisation. Lung Cancer 2000;28:225-35. (Pubitemid 30254230)
    • (2000) Lung Cancer , vol.28 , Issue.3 , pp. 225-235
    • Zojer, N.1    Dekan, G.2    Ackermann, J.3    Fiegl, M.4    Kaufmann, H.5    Drach, J.6    Huber, H.7
  • 26
    • 0035816267 scopus 로고    scopus 로고
    • Aneuploidy and prognosis of non-small-cell lung cancer: A meta-analysis of published data
    • DOI 10.1054/bjoc.2001.1892
    • Choma D, Daures JP, Quantin X, Pujol JL. Aneuploidy and prognosis of non-small-cell lung cancer: a meta-analysis of published data. Br J Cancer 2001;85:14-22. (Pubitemid 32695710)
    • (2001) British Journal of Cancer , vol.85 , Issue.1 , pp. 14-22
    • Choma, D.1    Daures, J.-P.2    Quantin, X.3    Pujol, J.L.4
  • 28
    • 33746502729 scopus 로고    scopus 로고
    • Adenosine diphosphate ribosyl transferase and x-ray repair cross-complementing 1 polymorphisms in gastric cardia cancer
    • Miao X, Zhang X, Zhang L, Guo Y, Hao B, Tan W, He F, Lin D. Adenosine diphosphate ribosyl transferase and x-ray repair cross-complementing 1 polymorphisms in gastric cardia cancer. Gastroenterology 2006;131:420-7.
    • (2006) Gastroenterology , vol.131 , pp. 420-427
    • Miao, X.1    Zhang, X.2    Zhang, L.3    Guo, Y.4    Hao, B.5    Tan, W.6    He, F.7    Lin, D.8
  • 29
    • 0030920202 scopus 로고    scopus 로고
    • Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro
    • Vasquez RJ, Howell B, Yvon AM, Wadsworth P, Cassimeris L. Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro. Mol Biol Cell 1997;8:973-85.
    • (1997) Mol Biol Cell , vol.8 , pp. 973-985
    • Vasquez, R.J.1    Howell, B.2    Yvon, A.M.3    Wadsworth, P.4    Cassimeris, L.5
  • 35
    • 0035890057 scopus 로고    scopus 로고
    • Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint
    • Sironi L, Melixetian M, Faretta M, Prosperini E, Helin K, Musacchio A. Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint. EMBO J 2001;20:6371-82.
    • (2001) EMBO J , vol.20 , pp. 6371-6382
    • Sironi, L.1    Melixetian, M.2    Faretta, M.3    Prosperini, E.4    Helin, K.5    Musacchio, A.6
  • 36
    • 0036161468 scopus 로고    scopus 로고
    • The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20
    • Luo X, Tang Z, Rizo J, Yu H. The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20. Mol Cell 2002;9:59-71.
    • (2002) Mol Cell , vol.9 , pp. 59-71
    • Luo, X.1    Tang, Z.2    Rizo, J.3    Yu, H.4
  • 38
    • 1842533070 scopus 로고    scopus 로고
    • Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells
    • Michel L, Diaz-Rodriguez E, Narayan G, Hernando E, Murty VV, Benezra R. Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells. Proc Natl Acad Sci U S A 2004;101:4459-64.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 4459-4464
    • Michel, L.1    Diaz-Rodriguez, E.2    Narayan, G.3    Hernando, E.4    Murty, V.V.5    Benezra, R.6
  • 39
    • 34447095664 scopus 로고    scopus 로고
    • Breast cancer risk associated with genotypic polymorphism of the mitotic checkpoint genes: A multigenic study on cancer susceptibility
    • Lo YL, Yu JC, Chen ST, Hsu GC, Mau YC, Yang SL, Wu PE, Shen CY. Breast cancer risk associated with genotypic polymorphism of the mitotic checkpoint genes: a multigenic study on cancer susceptibility. Carcinogenesis 2007;28:1079-86.
    • (2007) Carcinogenesis , vol.28 , pp. 1079-1086
    • Lo, Y.L.1    Yu, J.C.2    Chen, S.T.3    Hsu, G.C.4    Mau, Y.C.5    Yang, S.L.6    Wu, P.E.7    Shen, C.Y.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.