Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint

Cell

Volumn 106, Issue 1, 2001, Pages 83-93

  Abrieu, Ariane ^a   Magnaghi Jaulin, Laura ^b   Kahana, Jason A ^a   Peter, Marion ^b   Castro, Anna ^b   Vigneron, Suzanne ^b   Lorca, Thierry ^b   Cleveland, Don W ^a   Labbé, Jean Claude ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Centre National de la Recherche Scientifique   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHASE; ARTICLE; CENTROMERE; CONTROLLED STUDY; GENE ACTIVATION; MITOSIS RATE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; VERTEBRATE; XENOPUS; YEAST;

VERTEBRATA;

EID: 0035854379     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(01)00410-X     Document Type: Article

References (55)

1. CENP-E as an essential component of the mitotic checkpoint in vitro
2. Anaphase spindle position is monitored by the BUB2 checkpoint
3. Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function
4. The kinesin-like protein CENP-E is kinetochore-associated throughout poleward chromosome segregation during anaphase-A
5. Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC
6. Characterization of spindle assembly checkpoint in Xenopus egg extracts
7. Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores
8. Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores
9. The spindle checkpoint of budding yeast depends on a tight complex between the Mad1 and Mad2 proteins
10. Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p
11. Localization of CENP-E in the fibrous corona and outer plate of mammalian kinetochores from prometaphase through anaphase
12. Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2
13. Multiple cDNAs encoding the esk kinase predict transmembrane and intracellular enzyme isoforms
14. The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation
15. Bub1p kinase activates the Saccharomyces cerevisiae spindle assembly checkpoint
16. A Bub2p-dependent spindle checkpoint pathway regulates the Dbf2p kinase in budding yeast
17. The mouse Mps1p-like kinase regulates centrosome duplication
18. Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast
19. Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption
20. Cell cycle dependent regulation of the protein kinase TTK
21. Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor
22. Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells
23. S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function
24. The hBUB1 and hBUBR1 kinases sequentially assemble onto kinetochores during prophase with hBUBR1 concentrating at the kinetochore plates in mitosis
25. Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events
26. Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase
27. Feedback control of mitosis in budding yeast
28. Identification of a human mitotic checkpoint gene: hsMAD2
29. Ca2+ is involved through type II calmodulin-dependent protein kinase in cyclin degradation and exit from metaphase
30. Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts
31. Retention of the BUB3 checkpoint protein on lagging chromosomes
32. MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells
33. Expression of TTK, a novel human protein kinase, is associated with cell proliferation
34. A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts
35. The proteolysis-dependent metaphase to anaphase transition: Calcium/calmodulin-dependent protein kinase II mediates onset of anaphase in extracts prepared from unfertilized Xenopus eggs
36. Cell cycle extracts
37. The Bub2p spindle checkpoint links nuclear migration with mitotic exit
38. The vertebrate cell kinetochore and its roles during mitosis
39. The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase
40. The c-mos proto-oncogene product is a cytostatic factor responsible for meiotic arrest in vertebrate eggs
41. CENP-E function at kinetochores is essential for chromosome alignment
42. The yeast CDC37 gene interacts with MPS1 and is required for proper execution of spindle pole body duplication
43. Activation of the MKK/ERK pathway during somatic cell mitosis: Direct interactions of active ERK with kinetochores and regulation of the mitotic 3F3/2 phosphoantigen
44. Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage
45. The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase
46. XKCM1: A Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly
47. The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint
48. MPS1 and MPS2: Novel yeast genes defining distinct steps of spindle pole body duplication
49. CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignment
50. The microtubule-dependent motor centromere-associated protein E (CENP-E) is an integral component of kinetochore corona fibers that link centromeres to spindle microtubules
51. CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint
52. CENP-E is a putative kinetochore motor that accumulates just before mitosis
53. Progression into and out of mitosis
54. Active MAP kinase in mitosis: Localization at kinetochores and association with the motor protein CENP-E
55. Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis