-
1
-
-
48749090279
-
Mechanism of tau-induced neurodegeneration in Alzheimer disease and related tauopathies
-
Alonso A.C., Li B., Grundke-Iqbal I., Iqbal K. Mechanism of tau-induced neurodegeneration in Alzheimer disease and related tauopathies. Curr. Alzheimer Res. 2008, 5:375-384.
-
(2008)
Curr. Alzheimer Res.
, vol.5
, pp. 375-384
-
-
Alonso, A.C.1
Li, B.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
2
-
-
33750151420
-
The functions of mammalian amyloid precursor protein and related amyloid precursor-like proteins
-
Anliker B., Muller U. The functions of mammalian amyloid precursor protein and related amyloid precursor-like proteins. Neurodegener. Dis. 2006, 3:239-246.
-
(2006)
Neurodegener. Dis.
, vol.3
, pp. 239-246
-
-
Anliker, B.1
Muller, U.2
-
3
-
-
0026740795
-
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
-
Arriagada P.V., Growdon J.H., Hedley-Whyte E.T., Hyman B.T. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology 1992, 42:631-639.
-
(1992)
Neurology
, vol.42
, pp. 631-639
-
-
Arriagada, P.V.1
Growdon, J.H.2
Hedley-Whyte, E.T.3
Hyman, B.T.4
-
4
-
-
21344431624
-
Fasciclin II signals new synapse formation through amyloid precursor protein and the scaffolding protein dX11/Mint
-
Ashley J., Packard M., Ataman B., Budnik V. Fasciclin II signals new synapse formation through amyloid precursor protein and the scaffolding protein dX11/Mint. J. Neurosci. 2005, 25:5943-5955.
-
(2005)
J. Neurosci.
, vol.25
, pp. 5943-5955
-
-
Ashley, J.1
Packard, M.2
Ataman, B.3
Budnik, V.4
-
5
-
-
31544454404
-
Rapamycin alleviates toxicity of different aggregate-prone proteins
-
Berger Z., Ravikumar B., Menzies F.M., Oroz L.G., Underwood B.R., Pangalos M.N., Schmitt I., Wullner U., Evert B.O., O'Kane C.J., Rubinsztein D.C. Rapamycin alleviates toxicity of different aggregate-prone proteins. Hum. Mol. Genet. 2006, 15:433-442.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 433-442
-
-
Berger, Z.1
Ravikumar, B.2
Menzies, F.M.3
Oroz, L.G.4
Underwood, B.R.5
Pangalos, M.N.6
Schmitt, I.7
Wullner, U.8
Evert, B.O.9
O'Kane, C.J.10
Rubinsztein, D.C.11
-
6
-
-
20044362721
-
Family-based association between Alzheimer's disease and variants in UBQLN1
-
Bertram L., Hiltunen M., Parkinson M., Ingelsson M., Lange C., Ramasamy K., Mullin K., Menon R., Sampson A.J., Hsiao M.Y., Elliott K.J., Velicelebi G., Moscarillo T., Hyman B.T., Wagner S.L., Becker K.D., Blacker D., Tanzi R.E. Family-based association between Alzheimer's disease and variants in UBQLN1. N. Engl. J. Med. 2005, 352:884-894.
-
(2005)
N. Engl. J. Med.
, vol.352
, pp. 884-894
-
-
Bertram, L.1
Hiltunen, M.2
Parkinson, M.3
Ingelsson, M.4
Lange, C.5
Ramasamy, K.6
Mullin, K.7
Menon, R.8
Sampson, A.J.9
Hsiao, M.Y.10
Elliott, K.J.11
Velicelebi, G.12
Moscarillo, T.13
Hyman, B.T.14
Wagner, S.L.15
Becker, K.D.16
Blacker, D.17
Tanzi, R.E.18
-
7
-
-
18244384190
-
Disruption of the MAP1B-related protein FUTSCH leads to changes in the neuronal cytoskeleton, axonal transport defects, and progressive neurodegeneration in Drosophila
-
Bettencourt da Cruz A., Schwarzel M., Schulze S., Niyyati M., Heisenberg M., Kretzschmar D. Disruption of the MAP1B-related protein FUTSCH leads to changes in the neuronal cytoskeleton, axonal transport defects, and progressive neurodegeneration in Drosophila. Mol. Biol. Cell 2005, 16:2433-2442.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 2433-2442
-
-
Bettencourt da Cruz, A.1
Schwarzel, M.2
Schulze, S.3
Niyyati, M.4
Heisenberg, M.5
Kretzschmar, D.6
-
8
-
-
29444455075
-
Drosophila as a model for human neurodegenerative disease
-
Bilen J., Bonini N.M. Drosophila as a model for human neurodegenerative disease. Annu. Rev. Genet. 2005, 39:153-171.
-
(2005)
Annu. Rev. Genet.
, vol.39
, pp. 153-171
-
-
Bilen, J.1
Bonini, N.M.2
-
9
-
-
33749473333
-
Inhibition of proteasome and Shaggy/Glycogen synthase kinase-3beta kinase prevents clearance of phosphorylated tau in Drosophila
-
Blard O., Frebourg T., Campion D., Lecourtois M. Inhibition of proteasome and Shaggy/Glycogen synthase kinase-3beta kinase prevents clearance of phosphorylated tau in Drosophila. J. Neurosci. Res. 2006, 84:1107-1115.
-
(2006)
J. Neurosci. Res.
, vol.84
, pp. 1107-1115
-
-
Blard, O.1
Frebourg, T.2
Campion, D.3
Lecourtois, M.4
-
10
-
-
10944244158
-
Cultured cell and transgenic mouse models for tau pathology linked to beta-amyloid
-
Bloom G.S., Ren K., Glabe C.G. Cultured cell and transgenic mouse models for tau pathology linked to beta-amyloid. Biochim. Biophys. Acta 2005, 1739:116-124.
-
(2005)
Biochim. Biophys. Acta
, vol.1739
, pp. 116-124
-
-
Bloom, G.S.1
Ren, K.2
Glabe, C.G.3
-
11
-
-
45149093564
-
Identification of novel genes that modify phenotypes induced by Alzheimer's beta-amyloid overexpression in Drosophila
-
Cao W., Song H.J., Gangi T., Kelkar A., Antani I., Garza D., Konsolaki M. Identification of novel genes that modify phenotypes induced by Alzheimer's beta-amyloid overexpression in Drosophila. Genetics 2008, 178:1457-1471.
-
(2008)
Genetics
, vol.178
, pp. 1457-1471
-
-
Cao, W.1
Song, H.J.2
Gangi, T.3
Kelkar, A.4
Antani, I.5
Garza, D.6
Konsolaki, M.7
-
12
-
-
58149503769
-
Neurotoxic effects induced by the Drosophila amyloid-beta peptide suggest a conserved toxic function
-
Carmine-Simmen K., Proctor T., Tschape J., Poeck B., Triphan T., Strauss R., Kretzschmar D. Neurotoxic effects induced by the Drosophila amyloid-beta peptide suggest a conserved toxic function. Neurobiol. Dis. 2009, 33:274-281.
-
(2009)
Neurobiol. Dis.
, vol.33
, pp. 274-281
-
-
Carmine-Simmen, K.1
Proctor, T.2
Tschape, J.3
Poeck, B.4
Triphan, T.5
Strauss, R.6
Kretzschmar, D.7
-
13
-
-
0026075602
-
Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene
-
Chartier-Harlin M.C., Crawford F., Houlden H., Warren A., Hughes D., Fidani L., Goate A., Rossor M., Roques P., Hardy J., et al. Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene. Nature 1991, 353:844-846.
-
(1991)
Nature
, vol.353
, pp. 844-846
-
-
Chartier-Harlin, M.C.1
Crawford, F.2
Houlden, H.3
Warren, A.4
Hughes, D.5
Fidani, L.6
Goate, A.7
Rossor, M.8
Roques, P.9
Hardy, J.10
-
14
-
-
57649203362
-
Dissociation of tau toxicity and phosphorylation: role of GSK-3beta, MARK and Cdk5 in a Drosophila model
-
Chatterjee S., Sang T.K., Lawless G.M., Jackson G.R. Dissociation of tau toxicity and phosphorylation: role of GSK-3beta, MARK and Cdk5 in a Drosophila model. Hum. Mol. Genet. 2009, 18:164-177.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 164-177
-
-
Chatterjee, S.1
Sang, T.K.2
Lawless, G.M.3
Jackson, G.R.4
-
15
-
-
33744994326
-
Biochemical investigation of Tau protein phosphorylation status and its solubility properties in Drosophila
-
Chau K.W., Chan W.Y., Shaw P.C., Chan H.Y. Biochemical investigation of Tau protein phosphorylation status and its solubility properties in Drosophila. Biochem. Biophys. Res. Commun. 2006, 346:150-159.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.346
, pp. 150-159
-
-
Chau, K.W.1
Chan, W.Y.2
Shaw, P.C.3
Chan, H.Y.4
-
16
-
-
32544447773
-
Overexpression of tau results in defective synaptic transmission in Drosophila neuromuscular junctions
-
Chee F., Mudher A., Newman T.A., Cuttle M., Lovestone S., Shepherd D. Overexpression of tau results in defective synaptic transmission in Drosophila neuromuscular junctions. Biochem. Soc. Trans. 2006, 34:88-90.
-
(2006)
Biochem. Soc. Trans.
, vol.34
, pp. 88-90
-
-
Chee, F.1
Mudher, A.2
Newman, T.A.3
Cuttle, M.4
Lovestone, S.5
Shepherd, D.6
-
17
-
-
34247615021
-
Study of tauopathies by comparing Drosophila and human tau in Drosophila
-
Chen X., Li Y., Huang J., Cao D., Yang G., Liu W., Lu H., Guo A. Study of tauopathies by comparing Drosophila and human tau in Drosophila. Cell Tissue Res. 2007, 329:169-178.
-
(2007)
Cell Tissue Res.
, vol.329
, pp. 169-178
-
-
Chen, X.1
Li, Y.2
Huang, J.3
Cao, D.4
Yang, G.5
Liu, W.6
Lu, H.7
Guo, A.8
-
18
-
-
33748792821
-
Opposing activities protect against age-onset proteotoxicity
-
Cohen E., Bieschke J., Perciavalle R.M., Kelly J.W., Dillin A. Opposing activities protect against age-onset proteotoxicity. Science 2006, 313:1604-1610.
-
(2006)
Science
, vol.313
, pp. 1604-1610
-
-
Cohen, E.1
Bieschke, J.2
Perciavalle, R.M.3
Kelly, J.W.4
Dillin, A.5
-
19
-
-
15044339964
-
Intraneuronal Abeta, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer's disease
-
Crowther D.C., Kinghorn K.J., Miranda E., Page R., Curry J.A., Duthie F.A., Gubb D.C., Lomas D.A. Intraneuronal Abeta, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer's disease. Neuroscience 2005, 132:123-135.
-
(2005)
Neuroscience
, vol.132
, pp. 123-135
-
-
Crowther, D.C.1
Kinghorn, K.J.2
Miranda, E.3
Page, R.4
Curry, J.A.5
Duthie, F.A.6
Gubb, D.C.7
Lomas, D.A.8
-
20
-
-
0027333449
-
Apl-1, a Caenorhabditis elegans gene encoding a protein related to the human beta-amyloid protein precursor
-
Daigle I., Li C. apl-1, a Caenorhabditis elegans gene encoding a protein related to the human beta-amyloid protein precursor. Proc. Natl. Acad. Sci. U.S.A. 1993, 90:12045-12049.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 12045-12049
-
-
Daigle, I.1
Li, C.2
-
21
-
-
0037431082
-
Aph-1, Pen-2, and nicastrin with presenilin generate an active gamma-secretase complex
-
De Strooper B. Aph-1, Pen-2, and nicastrin with presenilin generate an active gamma-secretase complex. Neuron 2003, 38:9-12.
-
(2003)
Neuron
, vol.38
, pp. 9-12
-
-
De Strooper, B.1
-
22
-
-
0034049944
-
Proteolytic processing and cell biological functions of the amyloid precursor protein
-
De Strooper B., Annaert W. Proteolytic processing and cell biological functions of the amyloid precursor protein. J. Cell Sci. 2000, 113(Pt 11):1857-1870.
-
(2000)
J. Cell Sci.
, vol.113
, Issue.PART 11
, pp. 1857-1870
-
-
De Strooper, B.1
Annaert, W.2
-
23
-
-
33846080531
-
Oxidative stress mediates tau-induced neurodegeneration in Drosophila
-
Dias-Santagata D., Fulga T.A., Duttaroy A., Feany M.B. Oxidative stress mediates tau-induced neurodegeneration in Drosophila. J. Clin. Invest. 2007, 117:236-245.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 236-245
-
-
Dias-Santagata, D.1
Fulga, T.A.2
Duttaroy, A.3
Feany, M.B.4
-
24
-
-
0031712488
-
In vivo aggregation of beta-amyloid peptide variants
-
Fay D.S., Fluet A., Johnson C.J., Link C.D. In vivo aggregation of beta-amyloid peptide variants. J. Neurochem. 1998, 71:1616-1625.
-
(1998)
J. Neurochem.
, vol.71
, pp. 1616-1625
-
-
Fay, D.S.1
Fluet, A.2
Johnson, C.J.3
Link, C.D.4
-
25
-
-
34548812551
-
The role of amyloid beta peptide 42 in Alzheimer's disease
-
Findeis M.A. The role of amyloid beta peptide 42 in Alzheimer's disease. Pharmacol. Ther. 2007, 116:266-286.
-
(2007)
Pharmacol. Ther.
, vol.116
, pp. 266-286
-
-
Findeis, M.A.1
-
26
-
-
3242809725
-
A model for studying Alzheimer's Abeta42-induced toxicity in Drosophila melanogaster
-
Finelli A., Kelkar A., Song H.J., Yang H., Konsolaki M. A model for studying Alzheimer's Abeta42-induced toxicity in Drosophila melanogaster. Mol. Cell. Neurosci. 2004, 26:365-375.
-
(2004)
Mol. Cell. Neurosci.
, vol.26
, pp. 365-375
-
-
Finelli, A.1
Kelkar, A.2
Song, H.J.3
Yang, H.4
Konsolaki, M.5
-
27
-
-
77950972735
-
Abeta exacerbates the neuronal dysfunction caused by human tau expression in a Drosophila model of Alzheimer's disease
-
Folwell J., Cowan C.M., Ubhi K.K., Shiabh H., Newman T.A., Shepherd D., Mudher A. Abeta exacerbates the neuronal dysfunction caused by human tau expression in a Drosophila model of Alzheimer's disease. Exp. Neurol. 2009.
-
(2009)
Exp. Neurol.
-
-
Folwell, J.1
Cowan, C.M.2
Ubhi, K.K.3
Shiabh, H.4
Newman, T.A.5
Shepherd, D.6
Mudher, A.7
-
28
-
-
38149110518
-
Suppression of in vivo beta-amyloid peptide toxicity by overexpression of the HSP-16.2 small chaperone protein
-
Fonte V., Kipp D.R., Yerg J., Merin D., Forrestal M., Wagner E., Roberts C.M., Link C.D. Suppression of in vivo beta-amyloid peptide toxicity by overexpression of the HSP-16.2 small chaperone protein. J. Biol. Chem. 2008, 283:784-791.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 784-791
-
-
Fonte, V.1
Kipp, D.R.2
Yerg, J.3
Merin, D.4
Forrestal, M.5
Wagner, E.6
Roberts, C.M.7
Link, C.D.8
-
29
-
-
0032506013
-
Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype
-
Fossgreen A., Bruckner B., Czech C., Masters C.L., Beyreuther K., Paro R. Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:13703-13708.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 13703-13708
-
-
Fossgreen, A.1
Bruckner, B.2
Czech, C.3
Masters, C.L.4
Beyreuther, K.5
Paro, R.6
-
30
-
-
33947286683
-
Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo
-
Fulga T.A., Elson-Schwab I., Khurana V., Steinhilb M.L., Spires T.L., Hyman B.T., Feany M.B. Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo. Nat. Cell Biol. 2007, 9:139-148.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 139-148
-
-
Fulga, T.A.1
Elson-Schwab, I.2
Khurana, V.3
Steinhilb, M.L.4
Spires, T.L.5
Hyman, B.T.6
Feany, M.B.7
-
31
-
-
37849018692
-
Ubiquilin antagonizes presenilin and promotes neurodegeneration in Drosophila
-
Ganguly A., Feldman R.M., Guo M. ubiquilin antagonizes presenilin and promotes neurodegeneration in Drosophila. Hum. Mol. Genet. 2008, 17:293-302.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 293-302
-
-
Ganguly, A.1
Feldman, R.M.2
Guo, M.3
-
33
-
-
0021572660
-
The amyloid deposits in Alzheimer's disease: their nature and pathogenesis
-
Glenner G.G., Wong C.W., Quaranta V., Eanes E.D. The amyloid deposits in Alzheimer's disease: their nature and pathogenesis. Appl. Pathol. 1984, 2:357-369.
-
(1984)
Appl. Pathol.
, vol.2
, pp. 357-369
-
-
Glenner, G.G.1
Wong, C.W.2
Quaranta, V.3
Eanes, E.D.4
-
34
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
Goate A., Chartier-Harlin M.C., Mullan M., Brown J., Crawford F., Fidani L., Giuffra L., Haynes A., Irving N., James L., et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 1991, 349:704-706.
-
(1991)
Nature
, vol.349
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fidani, L.6
Giuffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
-
35
-
-
33746892301
-
Cell type-specific processing of human Tau proteins in Drosophila
-
Grammenoudi S., Kosmidis S., Skoulakis E.M. Cell type-specific processing of human Tau proteins in Drosophila. FEBS Lett. 2006, 580:4602-4606.
-
(2006)
FEBS Lett.
, vol.580
, pp. 4602-4606
-
-
Grammenoudi, S.1
Kosmidis, S.2
Skoulakis, E.M.3
-
36
-
-
2142645114
-
Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila
-
Greeve I., Kretzschmar D., Tschape J.A., Beyn A., Brellinger C., Schweizer M., Nitsch R.M., Reifegerste R. Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila. J. Neurosci. 2004, 24:3899-3906.
-
(2004)
J. Neurosci.
, vol.24
, pp. 3899-3906
-
-
Greeve, I.1
Kretzschmar, D.2
Tschape, J.A.3
Beyn, A.4
Brellinger, C.5
Schweizer, M.6
Nitsch, R.M.7
Reifegerste, R.8
-
37
-
-
0035829720
-
Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila
-
Gunawardena S., Goldstein L.S. Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila. Neuron 2001, 32:389-401.
-
(2001)
Neuron
, vol.32
, pp. 389-401
-
-
Gunawardena, S.1
Goldstein, L.S.2
-
38
-
-
65449156394
-
SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans
-
Guthrie C.R., Schellenberg G.D., Kraemer B.C. SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans. Hum. Mol. Genet. 2009, 18:1825-1838.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 1825-1838
-
-
Guthrie, C.R.1
Schellenberg, G.D.2
Kraemer, B.C.3
-
39
-
-
0033615580
-
The presenilins in Alzheimer's disease-proteolysis holds the key
-
Haass C., De Strooper B. The presenilins in Alzheimer's disease-proteolysis holds the key. Science 1999, 286:916-919.
-
(1999)
Science
, vol.286
, pp. 916-919
-
-
Haass, C.1
De Strooper, B.2
-
40
-
-
0034814018
-
Identification and characterization of the Drosophila tau homolog
-
Heidary G., Fortini M.E. Identification and characterization of the Drosophila tau homolog. Mech. Dev. 2001, 108:171-178.
-
(2001)
Mech. Dev.
, vol.108
, pp. 171-178
-
-
Heidary, G.1
Fortini, M.E.2
-
41
-
-
0038439322
-
Mushroom body memoir: from maps to models
-
Heisenberg M. Mushroom body memoir: from maps to models. Nat. Rev. Neurosci. 2003, 4:266-275.
-
(2003)
Nat. Rev. Neurosci.
, vol.4
, pp. 266-275
-
-
Heisenberg, M.1
-
42
-
-
0033680949
-
Drosophila Futsch/22C10 is a MAP1B-like protein required for dendritic and axonal development
-
Hummel T., Krukkert K., Roos J., Davis G., Klambt C. Drosophila Futsch/22C10 is a MAP1B-like protein required for dendritic and axonal development. Neuron 2000, 26:357-370.
-
(2000)
Neuron
, vol.26
, pp. 357-370
-
-
Hummel, T.1
Krukkert, K.2
Roos, J.3
Davis, G.4
Klambt, C.5
-
43
-
-
0032543684
-
Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17
-
Hutton M., Lendon C.L., Rizzu P., Baker M., Froelich S., Houlden H., Pickering-Brown S., Chakraverty S., Isaacs A., Grover A., Hackett J., Adamson J., Lincoln S., Dickson D., Davies P., Petersen R.C., Stevens M., de Graaff E., Wauters E., van Baren J., Hillebrand M., Joosse M., Kwon J.M., Nowotny P., Heutink P., et al. Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17. Nature 1998, 393:702-705.
-
(1998)
Nature
, vol.393
, pp. 702-705
-
-
Hutton, M.1
Lendon, C.L.2
Rizzu, P.3
Baker, M.4
Froelich, S.5
Houlden, H.6
Pickering-Brown, S.7
Chakraverty, S.8
Isaacs, A.9
Grover, A.10
Hackett, J.11
Adamson, J.12
Lincoln, S.13
Dickson, D.14
Davies, P.15
Petersen, R.C.16
Stevens, M.17
de Graaff, E.18
Wauters, E.19
van Baren, J.20
Hillebrand, M.21
Joosse, M.22
Kwon, J.M.23
Nowotny, P.24
Heutink, P.25
more..
-
44
-
-
2342473791
-
Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease
-
Iijima K., Liu H.P., Chiang A.S., Hearn S.A., Konsolaki M., Zhong Y. Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:6623-6628.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 6623-6628
-
-
Iijima, K.1
Liu, H.P.2
Chiang, A.S.3
Hearn, S.A.4
Konsolaki, M.5
Zhong, Y.6
-
45
-
-
45949102576
-
Abeta42 mutants with different aggregation profiles induce distinct pathologies in Drosophila
-
Iijima K., Chiang H.C., Hearn S.A., Hakker I., Gatt A., Shenton C., Granger L., Leung A., Iijima-Ando K., Zhong Y. Abeta42 mutants with different aggregation profiles induce distinct pathologies in Drosophila. PLoS ONE 2008, 3:e1703.
-
(2008)
PLoS ONE
, vol.3
-
-
Iijima, K.1
Chiang, H.C.2
Hearn, S.A.3
Hakker, I.4
Gatt, A.5
Shenton, C.6
Granger, L.7
Leung, A.8
Iijima-Ando, K.9
Zhong, Y.10
-
46
-
-
67349142329
-
Mechanisms of tau-induced neurodegeneration
-
Iqbal K., Liu F., Gong C.X., Alonso Adel C., Grundke-Iqbal I. Mechanisms of tau-induced neurodegeneration. Acta Neuropathol. 2009, 118:53-69.
-
(2009)
Acta Neuropathol.
, vol.118
, pp. 53-69
-
-
Iqbal, K.1
Liu, F.2
Gong, C.X.3
Alonso Adel, C.4
Grundke-Iqbal, I.5
-
47
-
-
0037118247
-
Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila
-
Jackson G.R., Wiedau-Pazos M., Sang T.K., Wagle N., Brown C.A., Massachi S., Geschwind D.H. Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila. Neuron 2002, 34:509-519.
-
(2002)
Neuron
, vol.34
, pp. 509-519
-
-
Jackson, G.R.1
Wiedau-Pazos, M.2
Sang, T.K.3
Wagle, N.4
Brown, C.A.5
Massachi, S.6
Geschwind, D.H.7
-
48
-
-
67650383731
-
Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors
-
Jacobsen K.T., Iverfeldt K. Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors. Cell. Mol. Life Sci. 2009, 66:2299-2318.
-
(2009)
Cell. Mol. Life Sci.
, vol.66
, pp. 2299-2318
-
-
Jacobsen, K.T.1
Iverfeldt, K.2
-
49
-
-
33644611017
-
Genetic association of ubiquilin with Alzheimer's disease and related quantitative measures
-
Kamboh M.I., Minster R.L., Feingold E., DeKosky S.T. Genetic association of ubiquilin with Alzheimer's disease and related quantitative measures. Mol. Psychiatry 2006, 11:273-279.
-
(2006)
Mol. Psychiatry
, vol.11
, pp. 273-279
-
-
Kamboh, M.I.1
Minster, R.L.2
Feingold, E.3
DeKosky, S.T.4
-
50
-
-
33748174617
-
A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration
-
Karsten S.L., Sang T.K., Gehman L.T., Chatterjee S., Liu J., Lawless G.M., Sengupta S., Berry R.W., Pomakian J., Oh H.S., Schulz C., Hui K.S., Wiedau-Pazos M., Vinters H.V., Binder L.I., Geschwind D.H., Jackson G.R. A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration. Neuron 2006, 51:549-560.
-
(2006)
Neuron
, vol.51
, pp. 549-560
-
-
Karsten, S.L.1
Sang, T.K.2
Gehman, L.T.3
Chatterjee, S.4
Liu, J.5
Lawless, G.M.6
Sengupta, S.7
Berry, R.W.8
Pomakian, J.9
Oh, H.S.10
Schulz, C.11
Hui, K.S.12
Wiedau-Pazos, M.13
Vinters, H.V.14
Binder, L.I.15
Geschwind, D.H.16
Jackson, G.R.17
-
51
-
-
31944434543
-
TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model
-
Khurana V., Lu Y., Steinhilb M.L., Oldham S., Shulman J.M., Feany M.B. TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model. Curr. Biol. 2006, 16:230-241.
-
(2006)
Curr. Biol.
, vol.16
, pp. 230-241
-
-
Khurana, V.1
Lu, Y.2
Steinhilb, M.L.3
Oldham, S.4
Shulman, J.M.5
Feany, M.B.6
-
52
-
-
34548389257
-
SUT-1 enables tau-induced neurotoxicity in C. elegans
-
Kraemer B.C., Schellenberg G.D. SUT-1 enables tau-induced neurotoxicity in C. elegans. Hum. Mol. Genet. 2007, 16:1959-1971.
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 1959-1971
-
-
Kraemer, B.C.1
Schellenberg, G.D.2
-
53
-
-
0042889049
-
Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy
-
Kraemer B.C., Zhang B., Leverenz J.B., Thomas J.H., Trojanowski J.Q., Schellenberg G.D. Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:9980-9985.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 9980-9985
-
-
Kraemer, B.C.1
Zhang, B.2
Leverenz, J.B.3
Thomas, J.H.4
Trojanowski, J.Q.5
Schellenberg, G.D.6
-
54
-
-
33646133424
-
Molecular pathways that influence human tau-induced pathology in Caenorhabditis elegans
-
Kraemer B.C., Burgess J.K., Chen J.H., Thomas J.H., Schellenberg G.D. Molecular pathways that influence human tau-induced pathology in Caenorhabditis elegans. Hum. Mol. Genet. 2006, 15:1483-1496.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 1483-1496
-
-
Kraemer, B.C.1
Burgess, J.K.2
Chen, J.H.3
Thomas, J.H.4
Schellenberg, G.D.5
-
56
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
Levy-Lahad E., Wasco W., Poorkaj P., Romano D.M., Oshima J., Pettingell W.H., Yu C.E., Jondro P.D., Schmidt S.D., Wang K., et al. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 1995, 269:973-977.
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
Romano, D.M.4
Oshima, J.5
Pettingell, W.H.6
Yu, C.E.7
Jondro, P.D.8
Schmidt, S.D.9
Wang, K.10
-
57
-
-
28644449284
-
Amyloid precursor protein promotes post-developmental neurite arborization in the Drosophila brain
-
Leyssen M., Ayaz D., Hebert S.S., Reeve S., De Strooper B., Hassan B.A. Amyloid precursor protein promotes post-developmental neurite arborization in the Drosophila brain. EMBO J. 2005, 24:2944-2955.
-
(2005)
EMBO J.
, vol.24
, pp. 2944-2955
-
-
Leyssen, M.1
Ayaz, D.2
Hebert, S.S.3
Reeve, S.4
De Strooper, B.5
Hassan, B.A.6
-
58
-
-
9144248022
-
Specific functions of Drosophila amyloid precursor-like protein in the development of nervous system and nonneural tissues
-
Li Y., Liu T., Peng Y., Yuan C., Guo A. Specific functions of Drosophila amyloid precursor-like protein in the development of nervous system and nonneural tissues. J. Neurobiol. 2004, 61:343-358.
-
(2004)
J. Neurobiol.
, vol.61
, pp. 343-358
-
-
Li, Y.1
Liu, T.2
Peng, Y.3
Yuan, C.4
Guo, A.5
-
59
-
-
35448970692
-
Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: in vivo interaction with early-onset Alzheimer disease genes
-
Li A., Xie Z., Dong Y., McKay K.M., McKee M.L., Tanzi R.E. Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: in vivo interaction with early-onset Alzheimer disease genes. Hum. Mol. Genet. 2007, 16:2626-2639.
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 2626-2639
-
-
Li, A.1
Xie, Z.2
Dong, Y.3
McKay, K.M.4
McKee, M.L.5
Tanzi, R.E.6
-
60
-
-
0028981288
-
Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans
-
Link C.D. Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 1995, 92:9368-9372.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 9368-9372
-
-
Link, C.D.1
-
61
-
-
33751397131
-
C. elegans models of age-associated neurodegenerative diseases: lessons from transgenic worm models of Alzheimer's disease
-
Link C.D. C. elegans models of age-associated neurodegenerative diseases: lessons from transgenic worm models of Alzheimer's disease. Exp. Gerontol. 2006, 41:1007-1013.
-
(2006)
Exp. Gerontol.
, vol.41
, pp. 1007-1013
-
-
Link, C.D.1
-
62
-
-
66149135641
-
Drosophila models of neurodegenerative diseases
-
Lu B., Vogel H. Drosophila models of neurodegenerative diseases. Annu. Rev. Pathol. 2009, 4:315-342.
-
(2009)
Annu. Rev. Pathol.
, vol.4
, pp. 315-342
-
-
Lu, B.1
Vogel, H.2
-
63
-
-
0025664016
-
Identification, secretion, and neural expression of APPL, a Drosophila protein similar to human amyloid protein precursor
-
Luo L.Q., Martin-Morris L.E., White K. Identification, secretion, and neural expression of APPL, a Drosophila protein similar to human amyloid protein precursor. J. Neurosci. 1990, 10:3849-3861.
-
(1990)
J. Neurosci.
, vol.10
, pp. 3849-3861
-
-
Luo, L.Q.1
Martin-Morris, L.E.2
White, K.3
-
64
-
-
0026783241
-
Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for Appl gene
-
Luo L., Tully T., White K. Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for Appl gene. Neuron 1992, 9:595-605.
-
(1992)
Neuron
, vol.9
, pp. 595-605
-
-
Luo, L.1
Tully, T.2
White, K.3
-
66
-
-
2542590202
-
Learning and memory deficits upon TAU accumulation in Drosophila mushroom body neurons
-
Mershin A., Pavlopoulos E., Fitch O., Braden B.C., Nanopoulos D.V., Skoulakis E.M. Learning and memory deficits upon TAU accumulation in Drosophila mushroom body neurons. Learn Mem. 2004, 11:277-287.
-
(2004)
Learn Mem.
, vol.11
, pp. 277-287
-
-
Mershin, A.1
Pavlopoulos, E.2
Fitch, O.3
Braden, B.C.4
Nanopoulos, D.V.5
Skoulakis, E.M.6
-
67
-
-
3142592230
-
GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila
-
Mudher A., Shepherd D., Newman T.A., Mildren P., Jukes J.P., Squire A., Mears A., Drummond J.A., Berg S., MacKay D., Asuni A.A., Bhat R., Lovestone S. GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila. Mol. Psychiatry. 2004, 9:522-530.
-
(2004)
Mol. Psychiatry.
, vol.9
, pp. 522-530
-
-
Mudher, A.1
Shepherd, D.2
Newman, T.A.3
Mildren, P.4
Jukes, J.P.5
Squire, A.6
Mears, A.7
Drummond, J.A.8
Berg, S.9
MacKay, D.10
Asuni, A.A.11
Bhat, R.12
Lovestone, S.13
-
68
-
-
0031795344
-
In vivo dynamics of axon pathfinding in the Drosophila CNS: a time-lapse study of an identified motorneuron
-
Murray M.J., Merritt D.J., Brand A.H., Whitington P.M. In vivo dynamics of axon pathfinding in the Drosophila CNS: a time-lapse study of an identified motorneuron. J. Neurobiol. 1998, 37:607-621.
-
(1998)
J. Neurobiol.
, vol.37
, pp. 607-621
-
-
Murray, M.J.1
Merritt, D.J.2
Brand, A.H.3
Whitington, P.M.4
-
69
-
-
67049159505
-
Is Alzheimer's disease a result of presynaptic failure? Synaptic dysfunctions induced by oligomeric beta-amyloid
-
Nimmrich V., Ebert U. Is Alzheimer's disease a result of presynaptic failure? Synaptic dysfunctions induced by oligomeric beta-amyloid. Rev. Neurosci. 2009, 20:1-12.
-
(2009)
Rev. Neurosci.
, vol.20
, pp. 1-12
-
-
Nimmrich, V.1
Ebert, U.2
-
70
-
-
1542358895
-
PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila
-
Nishimura I., Yang Y., Lu B. PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila. Cell 2004, 116:671-682.
-
(2004)
Cell
, vol.116
, pp. 671-682
-
-
Nishimura, I.1
Yang, Y.2
Lu, B.3
-
71
-
-
22344438508
-
Tau suppression in a neurodegenerative mouse model improves memory function
-
Santacruz K., Lewis J., Spires T., Paulson J., Kotilinek L., Ingelsson M., Guimaraes A., DeTure M., Ramsden M., McGowan E., Forster C., Yue M., Orne J., Janus C., Mariash A., Kuskowski M., Hyman B., Hutton M., Ashe K.H. Tau suppression in a neurodegenerative mouse model improves memory function. Science 2005, 309:476-481.
-
(2005)
Science
, vol.309
, pp. 476-481
-
-
Santacruz, K.1
Lewis, J.2
Spires, T.3
Paulson, J.4
Kotilinek, L.5
Ingelsson, M.6
Guimaraes, A.7
DeTure, M.8
Ramsden, M.9
McGowan, E.10
Forster, C.11
Yue, M.12
Orne, J.13
Janus, C.14
Mariash, A.15
Kuskowski, M.16
Hyman, B.17
Hutton, M.18
Ashe, K.H.19
-
72
-
-
0034516988
-
Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein
-
Selkoe D.J. Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein. Ann N Y Acad Sci. 2000, 924:17-25.
-
(2000)
Ann N Y Acad Sci.
, vol.924
, pp. 17-25
-
-
Selkoe, D.J.1
-
73
-
-
44549087765
-
Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior
-
Selkoe D.J. Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior. Behav. Brain Res. 2008, 192:106-113.
-
(2008)
Behav. Brain Res.
, vol.192
, pp. 106-113
-
-
Selkoe, D.J.1
-
74
-
-
33748426487
-
Unraveling in vivo functions of amyloid precursor protein: insights from knockout and knockdown studies
-
Senechal Y., Larmet Y., Dev K.K. Unraveling in vivo functions of amyloid precursor protein: insights from knockout and knockdown studies. Neurodegener. Dis. 2006, 3:134-147.
-
(2006)
Neurodegener. Dis.
, vol.3
, pp. 134-147
-
-
Senechal, Y.1
Larmet, Y.2
Dev, K.K.3
-
75
-
-
8944241774
-
Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant
-
Sherrington R., Froelich S., Sorbi S., Campion D., Chi H., Rogaeva E.A., Levesque G., Rogaev E.I., Lin C., Liang Y., Ikeda M., Mar L., Brice A., Agid Y., Percy M.E., Clerget-Darpoux F., Piacentini S., Marcon G., Nacmias B., Amaducci L., Frebourg T., Lannfelt L., Rommens J.M., St George-Hyslop P.H. Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant. Hum. Mol. Genet. 1996, 5:985-988.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 985-988
-
-
Sherrington, R.1
Froelich, S.2
Sorbi, S.3
Campion, D.4
Chi, H.5
Rogaeva, E.A.6
Levesque, G.7
Rogaev, E.I.8
Lin, C.9
Liang, Y.10
Ikeda, M.11
Mar, L.12
Brice, A.13
Agid, Y.14
Percy, M.E.15
Clerget-Darpoux, F.16
Piacentini, S.17
Marcon, G.18
Nacmias, B.19
Amaducci, L.20
Frebourg, T.21
Lannfelt, L.22
Rommens, J.M.23
St George-Hyslop, P.H.24
more..
-
76
-
-
0346361872
-
Genetic modifiers of tauopathy in Drosophila
-
Shulman J.M., Feany M.B. Genetic modifiers of tauopathy in Drosophila. Genetics 2003, 165:1233-1242.
-
(2003)
Genetics
, vol.165
, pp. 1233-1242
-
-
Shulman, J.M.1
Feany, M.B.2
-
77
-
-
0032769705
-
Direct observation of microtubule-f-actin interaction in cell free lysates
-
Sider J.R., Mandato C.A., Weber K.L., Zandy A.J., Beach D., Finst R.J., Skoble J., Bement W.M. Direct observation of microtubule-f-actin interaction in cell free lysates. J. Cell Sci. 1999, 112(Pt 12):1947-1956.
-
(1999)
J. Cell Sci.
, vol.112
, Issue.PART 12
, pp. 1947-1956
-
-
Sider, J.R.1
Mandato, C.A.2
Weber, K.L.3
Zandy, A.J.4
Beach, D.5
Finst, R.J.6
Skoble, J.7
Bement, W.M.8
-
78
-
-
0032560487
-
Mutation in the tau gene in familial multiple system tauopathy with presenile dementia
-
Spillantini M.G., Murrell J.R., Goedert M., Farlow M.R., Klug A., Ghetti B. Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:7737-7741.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 7737-7741
-
-
Spillantini, M.G.1
Murrell, J.R.2
Goedert, M.3
Farlow, M.R.4
Klug, A.5
Ghetti, B.6
-
79
-
-
37049027122
-
Tau phosphorylation sites work in concert to promote neurotoxicity in vivo
-
Steinhilb M.L., Dias-Santagata D., Fulga T.A., Felch D.L., Feany M.B. Tau phosphorylation sites work in concert to promote neurotoxicity in vivo. Mol. Biol. Cell 2007, 18:5060-5068.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 5060-5068
-
-
Steinhilb, M.L.1
Dias-Santagata, D.2
Fulga, T.A.3
Felch, D.L.4
Feany, M.B.5
-
80
-
-
34248219026
-
S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila
-
Steinhilb M.L., Dias-Santagata D., Mulkearns E.E., Shulman J.M., Biernat J., Mandelkow E.M., Feany M.B. S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila. J. Neurosci. Res. 2007, 85:1271-1278.
-
(2007)
J. Neurosci. Res.
, vol.85
, pp. 1271-1278
-
-
Steinhilb, M.L.1
Dias-Santagata, D.2
Mulkearns, E.E.3
Shulman, J.M.4
Biernat, J.5
Mandelkow, E.M.6
Feany, M.B.7
-
81
-
-
70350370787
-
What have worm models told us about the mechanisms of neuronal dysfunction in human neurodegenerative diseases?
-
Teschendorf D., Link C.D. What have worm models told us about the mechanisms of neuronal dysfunction in human neurodegenerative diseases?. Mol. Neurodegener. 2009, 4:38.
-
(2009)
Mol. Neurodegener.
, vol.4
, pp. 38
-
-
Teschendorf, D.1
Link, C.D.2
-
82
-
-
60549094390
-
Par-1 and Tau regulate the anterior-posterior gradient of microtubules in Drosophila oocytes
-
Tian A.G., Deng W.M. Par-1 and Tau regulate the anterior-posterior gradient of microtubules in Drosophila oocytes. Dev. Biol. 2009, 327:458-464.
-
(2009)
Dev. Biol.
, vol.327
, pp. 458-464
-
-
Tian, A.G.1
Deng, W.M.2
-
83
-
-
0033529031
-
Neuronal overexpression of APPL, the Drosophila homologue of the amyloid precursor protein (APP), disrupts axonal transport
-
Torroja L., Chu H., Kotovsky I., White K. Neuronal overexpression of APPL, the Drosophila homologue of the amyloid precursor protein (APP), disrupts axonal transport. Curr. Biol. 1999, 9:489-492.
-
(1999)
Curr. Biol.
, vol.9
, pp. 489-492
-
-
Torroja, L.1
Chu, H.2
Kotovsky, I.3
White, K.4
-
84
-
-
0033568874
-
The Drosophila beta-amyloid precursor protein homolog promotes synapse differentiation at the neuromuscular junction
-
Torroja L., Packard M., Gorczyca M., White K., Budnik V. The Drosophila beta-amyloid precursor protein homolog promotes synapse differentiation at the neuromuscular junction. J. Neurosci. 1999, 19:7793-7803.
-
(1999)
J. Neurosci.
, vol.19
, pp. 7793-7803
-
-
Torroja, L.1
Packard, M.2
Gorczyca, M.3
White, K.4
Budnik, V.5
-
85
-
-
0037011118
-
The neurodegeneration mutant lochrig interferes with cholesterol homeostasis and Appl processing
-
Tschape J.A., Hammerschmied C., Muhlig-Versen M., Athenstaedt K., Daum G., Kretzschmar D. The neurodegeneration mutant lochrig interferes with cholesterol homeostasis and Appl processing. EMBO J. 2002, 21:6367-6376.
-
(2002)
EMBO J.
, vol.21
, pp. 6367-6376
-
-
Tschape, J.A.1
Hammerschmied, C.2
Muhlig-Versen, M.3
Athenstaedt, K.4
Daum, G.5
Kretzschmar, D.6
-
86
-
-
0042634362
-
Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory
-
Turner P.R., O'Connor K., Tate W.P., Abraham W.C. Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory. Prog. Neurobiol. 2003, 70:1-32.
-
(2003)
Prog. Neurobiol.
, vol.70
, pp. 1-32
-
-
Turner, P.R.1
O'Connor, K.2
Tate, W.P.3
Abraham, W.C.4
-
87
-
-
34548317186
-
A comparison of the neuronal dysfunction caused by Drosophila tau and human tau in a Drosophila model of tauopathies
-
Ubhi K.K., Shaibah H., Newman T.A., Shepherd D., Mudher A. A comparison of the neuronal dysfunction caused by Drosophila tau and human tau in a Drosophila model of tauopathies. Invert. Neurosci. 2007, 7:165-171.
-
(2007)
Invert. Neurosci.
, vol.7
, pp. 165-171
-
-
Ubhi, K.K.1
Shaibah, H.2
Newman, T.A.3
Shepherd, D.4
Mudher, A.5
-
88
-
-
66149108459
-
Identifying genes that interact with Drosophila presenilin and amyloid precursor protein
-
van de Hoef D.L., Hughes J., Livne-Bar I., Garza D., Konsolaki M., Boulianne G.L. Identifying genes that interact with Drosophila presenilin and amyloid precursor protein. Genesis 2009, 47:246-260.
-
(2009)
Genesis
, vol.47
, pp. 246-260
-
-
van de Hoef, D.L.1
Hughes, J.2
Livne-Bar, I.3
Garza, D.4
Konsolaki, M.5
Boulianne, G.L.6
-
89
-
-
33846448743
-
Activation of PAR-1 kinase and stimulation of tau phosphorylation by diverse signals require the tumor suppressor protein LKB1
-
Wang J.W., Imai Y., Lu B. Activation of PAR-1 kinase and stimulation of tau phosphorylation by diverse signals require the tumor suppressor protein LKB1. J. Neurosci. 2007, 27:574-581.
-
(2007)
J. Neurosci.
, vol.27
, pp. 574-581
-
-
Wang, J.W.1
Imai, Y.2
Lu, B.3
-
90
-
-
0034716223
-
Tau and tau reporters disrupt central projections of sensory neurons in Drosophila
-
Williams D.W., Tyrer M., Shepherd D. Tau and tau reporters disrupt central projections of sensory neurons in Drosophila. J. Comp. Neurol. 2000, 428:630-640.
-
(2000)
J. Comp. Neurol.
, vol.428
, pp. 630-640
-
-
Williams, D.W.1
Tyrer, M.2
Shepherd, D.3
-
91
-
-
0035958642
-
Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles
-
Wittmann C.W., Wszolek M.F., Shulman J.M., Salvaterra P.M., Lewis J., Hutton M., Feany M.B. Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles. Science 2001, 293:711-714.
-
(2001)
Science
, vol.293
, pp. 711-714
-
-
Wittmann, C.W.1
Wszolek, M.F.2
Shulman, J.M.3
Salvaterra, P.M.4
Lewis, J.5
Hutton, M.6
Feany, M.B.7
-
92
-
-
0022297190
-
Neuritic plaques and cerebrovascular amyloid in Alzheimer disease are antigenically related
-
Wong C.W., Quaranta V., Glenner G.G. Neuritic plaques and cerebrovascular amyloid in Alzheimer disease are antigenically related. Proc. Natl. Acad. Sci. U. S. A. 1985, 82:8729-8732.
-
(1985)
Proc. Natl. Acad. Sci. U. S. A.
, vol.82
, pp. 8729-8732
-
-
Wong, C.W.1
Quaranta, V.2
Glenner, G.G.3
-
93
-
-
25844462819
-
Transgenic C. elegans as a model in Alzheimer's research
-
Wu Y., Luo Y. Transgenic C. elegans as a model in Alzheimer's research. Curr. Alzheimer Res. 2005, 2:37-45.
-
(2005)
Curr. Alzheimer Res.
, vol.2
, pp. 37-45
-
-
Wu, Y.1
Luo, Y.2
-
94
-
-
33845613251
-
Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans
-
Wu Y., Wu Z., Butko P., Christen Y., Lambert M.P., Klein W.L., Link C.D., Luo Y. Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans. J. Neurosci. 2006, 26:13102-13113.
-
(2006)
J. Neurosci.
, vol.26
, pp. 13102-13113
-
-
Wu, Y.1
Wu, Z.2
Butko, P.3
Christen, Y.4
Lambert, M.P.5
Klein, W.L.6
Link, C.D.7
Luo, Y.8
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