Hypoxia-inducible factor (HIF)-3α is subject to extensive alternative splicing in human tissues and cancer cells and is regulated by HIF-1 but not HIF-2

International Journal of Biochemistry and Cell Biology

Volumn 42, Issue 7, 2010, Pages 1189-1200

  Pasanen, Annika ^a   Heikkilä, Minna ^a   Rautavuoma, Kati ^a   Hirsilä, Maija ^a   Kivirikko, Kari I ^a   Myllyharju, Johanna ^a  

^a UNIVERSITY OF OULU   (Finland)

Author keywords

Alternative splicing; Cancer cells; Hypoxia response; Hypoxia inducible factor; Hypoxia inducible factor isoform 3

Indexed keywords

COMPLEMENTARY DNA; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 2; HYPOXIA INDUCIBLE FACTOR 3ALPHA; RNA; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; HIF3A PROTEIN, HUMAN; MESSENGER RNA; MUTANT PROTEIN;

ADULT; ALTERNATIVE RNA SPLICING; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CONTROLLED STUDY; DNA SYNTHESIS; FETUS; HEPATOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA ISOLATION; TRANSCRIPTION INITIATION; UPREGULATION; WESTERN BLOTTING; CELL HYPOXIA; CHEMISTRY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; METHYLATION; NEOPLASM; PATHOLOGY; TRANSCRIPTION INITIATION SITE; TUMOR CELL LINE;

ALTERNATIVE SPLICING; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL HYPOXIA; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; METHYLATION; MUTANT PROTEINS; NEOPLASMS; RNA, MESSENGER; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC;

EID: 77955692247     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2010.04.008     Document Type: Article

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