Binding and regulation of hypoxia-inducible factor-1 by the inhibitory PAS proteins

Biochemical and Biophysical Research Communications

Volumn 337, Issue 1, 2005, Pages 209-215

  Mi, Sun Jang ^a   Jae, Eun Park ^a   Lee, Jung A ^a   Sung, Goo Park ^a   Pyung, Keun Myung ^b   Lee, Do Hee ^a   Park, Byoung Chul ^a   Cho, Sayeon ^c  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Chungnam National University   (South Korea)

^c Chung Ang University   (South Korea)

Author keywords

Angiogenesis; Hypoxia; Hypoxia inducible factor 1 ; Inhibitory PAS domain protein

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CELL MIGRATION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HYPOXIA; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; REGULATORY MECHANISM; UMBILICAL VEIN;

AMINO ACID SEQUENCE; ANIMALS; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; CELL HYPOXIA; CELL LINE; CELL MOVEMENT; DNA-BINDING PROTEINS; ENDOTHELIUM, VASCULAR; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MOLECULAR SEQUENCE DATA; NEOVASCULARIZATION, PHYSIOLOGIC; RECEPTORS, ARYL HYDROCARBON; REPRESSOR PROTEINS; SEQUENCE ALIGNMENT; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 25844514738     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.09.038     Document Type: Article

References (25)

1. R.K. Bruick Oxygen sensing in the hypoxic response pathway: regulation of the hypoxia-inducible transcription factor Genes Dev. 17 2003 2614 2623
2. P.J. Ratcliffe, J.F. O'Rourke, P.H. Maxwell, and C.W. Pugh Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression J. Exp. Biol. 201 Pt. 8 1998 1153 1162
3. G.L. Semenza Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology Trends Mol. Med. 7 2001 345 350
4. G.L. Wang, and G.L. Semenza Purification and characterization of hypoxia-inducible factor 1 J. Biol. Chem. 270 1995 1230 1237
5. G.L. Wang, B.H. Jiang, E.A. Rue, and G.L. Semenza Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension Proc. Natl. Acad. Sci. USA 92 1995 5510 5514
6. T. Kamura, S. Sato, K. Iwai, M. Czyzyk-Krzeska, R.C. Conaway, and J.W. Conaway Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex Proc. Natl. Acad. Sci. USA 97 2000 10430 10435
7. P.H. Maxwell, M.S. Wiesener, G.W. Chang, S.C. Clifford, E.C. Vaux, M.E. Cockman, C.C. Wykoff, C.W. Pugh, E.R. Maher, and P.J. Ratcliffe The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis Nature 399 1999 271 275
8. R.K. Bruick, and S.L. McKnight A conserved family of prolyl-4- hydroxylases that modify HIF Science 294 2001 1337 1340
9. Y.Z. Gu, S.M. Moran, J.B. Hogenesch, L. Wartman, and C.A. Bradfield Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha Gene Expr. 7 1998 205 213
10. H. Tian, S.L. McKnight, and D.W. Russell Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells Genes Dev. 11 1997 72 82
11. R.H. Wenger Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression FASEB J. 16 2002 1151 1162
12. Y. Makino, R. Cao, K. Svensson, G. Bertilsson, M. Asman, H. Tanaka, Y. Cao, A. Berkenstam, and L. Poellinger Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression Nature 414 2001 550 554
13. Y. Makino, A. Kanopka, W.J. Wilson, H. Tanaka, and L. Poellinger Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible splicing variant of the hypoxia-inducible factor-3alpha locus J. Biol. Chem. 277 2002 32405 32408
14. M.A. Maynard, H. Qi, J. Chung, E.H. Lee, Y. Kondo, S. Hara, R.C. Conaway, J.W. Conaway, and M. Ohh Multiple splice variants of the human HIF-3alpha locus are targets of the VHL E3 ubiquitin ligase complex J. Biol. Chem. 21 2003 21
15. J.W. Lee, S.H. Bae, J.W. Jeong, S.H. Kim, and K.W. Kim Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions Exp. Mol. Med. 36 2004 1 12
16. W.S. Pear, G.P. Nolan, M.L. Scott, and D. Baltimore Production of high-titer helper-free retroviruses by transient transfection Proc. Natl. Acad. Sci. USA 90 1993 8392 8396
17. M. Ema, S. Taya, N. Yokotani, K. Sogawa, Y. Matsuda, and Y. Fujii-Kuriyama A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development Proc. Natl. Acad. Sci. USA 94 1997 4273 4278
18. S. Cho, H.M. Ko, J.M. Kim, J.A. Lee, J.E. Park, M.S. Jang, S.G. Park, H. Lee do, S.E. Ryu, and B.C. Park Positive regulation of apoptosis signal-regulating kinase 1 by hD53L1 J. Biol. Chem. 279 2004 16050 16056
19. S. Cho, Y.J. Choi, J.M. Kim, S.T. Jeong, J.H. Kim, S.H. Kim, and S.E. Ryu Binding and regulation of HIF-1alpha by a subunit of the proteasome complex, PSMA7 FEBS Lett. 498 2001 62 66
20. C.W. Kim, H.M. Lee, T.H. Lee, C. Kang, H.K. Kleinman, and Y.S. Gho Extracellular membrane vesicles from tumor cells promote angiogenesis via sphingomyelin Cancer Res. 62 2002 6312 6317
21. L. Favot, T. Keravis, V. Holl, A. Le Bec, and C. Lugnier VEGF-induced HUVEC migration and proliferation are decreased by PDE2 and PDE4 inhibitors Thromb. Haemost. 90 2003 334 343
22. K. Yamamoto, T. Takahashi, T. Asahara, N. Ohura, T. Sokabe, A. Kamiya, and J. Ando Proliferation, differentiation, and tube formation by endothelial progenitor cells in response to shear stress J. Appl. Physiol. 95 2003 2081 2088
23. D.E. Richard, E. Berra, and J. Pouyssegur Angiogenesis: how a tumor adapts to hypoxia Biochem. Biophys. Res. Commun. 266 1999 718 722
24. P. Buchler, H.A. Reber, M. Buchler, S. Shrinkante, M.W. Buchler, H. Friess, G.L. Semenza, and O.J. Hines Hypoxia-inducible factor 1 regulates vascular endothelial growth factor expression in human pancreatic cancer Pancreas 26 2003 56 64
25. S. Hara, J. Hamada, C. Kobayashi, Y. Kondo, and N. Imura Expression and characterization of hypoxia-inducible factor (HIF)-3alpha in human kidney: suppression of HIF-mediated gene expression by HIF-3alpha Biochem. Biophys. Res. Commun. 287 2001 808 813