Quantifying the proteolytic release of extracellular matrix-sequestered VEGF with a computational model

PLoS ONE

Volumn 5, Issue 7, 2010, Pages

  Vempati, Prakash ^a   Mac Gabhann, Feilim ^b   Popel, Aleksander S ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Johns Hopkins University School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MATRIX METALLOPROTEINASE; NEUROPILIN 1; PLASMIN; PROTEINASE; PROTEOHEPARAN SULFATE; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN 114; VASCULOTROPIN 165; VASCULOTROPIN RECEPTOR;

ARTICLE; AUTOCRINE EFFECT; BINDING KINETICS; CELL FUNCTION; CELL SURFACE; CELL TYPE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME SUBSTRATE COMPLEX; EXTRACELLULAR MATRIX; GEOMETRY; IN VIVO STUDY; INTERNALIZATION; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MOLECULAR MODEL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; SOLUBILITY; ANIMAL; BASEMENT MEMBRANE; COMPUTER SIMULATION; HUMAN; METABOLISM; THEORETICAL MODEL;

ANIMALS; BASEMENT MEMBRANE; COMPUTER SIMULATION; EXTRACELLULAR MATRIX; HUMANS; MODELS, THEORETICAL; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 77955636443     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011860     Document Type: Article

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