Heparin and fragments modulate the expression of collagen-degrading enzymes (matrix metalloproteinases 1 and 2) by human gingival fibroblasts

Annals of the New York Academy of Sciences

Volumn 878, Issue , 1999, Pages 625-628

  Hornebeck, W ^a   Gogly, B ^b   Godeau, G ^b   Emonard, H ^a   Pellat, B ^b  

^a UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

^b Laboratoire de Biochimie et Analise d'Images   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; GELATINASE A; HEPARIN;

CELL CULTURE; COLLAGEN DEGRADATION; CONFERENCE PAPER; CONTROLLED STUDY; FIBROBLAST; GINGIVA; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PERIODONTITIS;

EID: 0032838247     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb07745.x     Document Type: Conference Paper

References (7)

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3. 3. Havemose-Poulsen, A. & P. Holmstrup. 1997. Factors affecting IL-1-mediated collagen metabolism by fibroblasts and the pathogenesis of periodontal disease: a review of the literature. Crit. Rev. Oral Biol. Med. 8: 217-236.
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5. 5. Au, Y.P.T., K.F. Montgomery & A.W. Clowes. 1992. Heparin inhibits collagenase gene expression mediated by phorbol ester-responsive element in primate arterial smooth muscle cells. Circ. Res. 70: 1062-1069.
6. 6. Gogly, B., W. Hornebeck, N. Groult, G. Godeau & B. Pellat. 1998. Influence of heparin(s) on the interleukin-1β-induced expressions of collagenase, stromelysin-1 and tissue inhibitor of metalloproteinases-1 in human gingival fibroblasts. Biochem. Pharmacol. 56: 1447-1454.
7. 7. Lo, Y.Y.C., L. Luo, C.A.G. McCulloch & T.F. Cruz. 1998. Requirements of focal adhesions and calcium fluxes for interleukin-1-induced ERK kinase activation and c-fos expression in fibroblasts. J. Biol. Chem. 273: 7059-7065.