Extracellular cleavage of the vascular endothelial growth factor 189- amino acid form by urokinase is required for its mitogenic effect

Journal of Biological Chemistry

Volumn 272, Issue 20, 1997, Pages 13390-13396

  Plouët, Jean ^a   Moro, Francoise ^a   Bertagnolli, Stéphane ^a   Coldeboeuf, Nadine ^a   Mazarguil, Honore ^b   Clamens, Simone ^c   Bayard, Francis ^c  

^a CNRS   (France)

^b INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

^c CHU RANGUEIL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSAMINOGLYCAN; HEPARIN; MESSENGER RNA; PLASMIN; RECOMBINANT PROTEIN; SERINE PROTEINASE; SYNTHETIC PEPTIDE; UROKINASE; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHO CELL; CONTROLLED STUDY; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PURIFICATION;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CHO CELLS; CRICETINAE; ENDOTHELIAL GROWTH FACTORS; LYMPHOKINES; MITOGENS; MOLECULAR SEQUENCE DATA; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, GROWTH FACTOR; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; INSECTA; UNIDENTIFIED BACULOVIRUS;

EID: 0030976894     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.20.13390     Document Type: Article

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