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Volumn 179, Issue 6, 2007, Pages 1261-1273

Newly identified biologically active and proteolysis-resistant VEGF-A isoform VEGF111 is induced by genotoxic agents

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RECOMBINANT VASCULOTROPIN; TOXIN; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL GROWTH FACTOR 111; VASCULOTROPIN 121; VASCULOTROPIN 165; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 2;

EID: 37249059009     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200703052     Document Type: Article
Times cited : (80)

References (40)
  • 1
    • 0037098860 scopus 로고    scopus 로고
    • VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma
    • Bates, D.O., T.G. Cui, J.M. Doughty, M. Winkler, M. Sugiono, J.D. Shields, D. Peat, D. Gillatt, and S.J. Harper. 2002. VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma. Cancer Res. 62:4123-4131.
    • (2002) Cancer Res , vol.62 , pp. 4123-4131
    • Bates, D.O.1    Cui, T.G.2    Doughty, J.M.3    Winkler, M.4    Sugiono, M.5    Shields, J.D.6    Peat, D.7    Gillatt, D.8    Harper, S.J.9
  • 3
    • 0026756163 scopus 로고
    • Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing
    • Brown, L.F., K.T. Yeo, B. Berse, T.K. Yeo, D.R. Senger, H.F. Dvorak, and L. van de Water. 1992. Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing. J. Exp. Med. 176:1375-1379.
    • (1992) J. Exp. Med , vol.176 , pp. 1375-1379
    • Brown, L.F.1    Yeo, K.T.2    Berse, B.3    Yeo, T.K.4    Senger, D.R.5    Dvorak, H.F.6    van de Water, L.7
  • 4
    • 24144464544 scopus 로고    scopus 로고
    • Application of angiogenic factors for therapy of erectile dysfunction: Protein and DNA transfer of VEGF 165 into the rat penis
    • Burchardt, M., T. Burchardt, A.G. Anastasiadis, R. Buttyan, A. de la Taille, A. Shabsigh, J. Frank, and R. Shabsigh. 2005. Application of angiogenic factors for therapy of erectile dysfunction: protein and DNA transfer of VEGF 165 into the rat penis. Urology. 66:665-670.
    • (2005) Urology , vol.66 , pp. 665-670
    • Burchardt, M.1    Burchardt, T.2    Anastasiadis, A.G.3    Buttyan, R.4    de la Taille, A.5    Shabsigh, A.6    Frank, J.7    Shabsigh, R.8
  • 7
    • 0018639079 scopus 로고
    • Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
    • Chirgwin, J.M., A.E. Przybyla, R.J. MacDonald, and W.J. Rutter. 1979. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry. 18:5294-5299.
    • (1979) Biochemistry , vol.18 , pp. 5294-5299
    • Chirgwin, J.M.1    Przybyla, A.E.2    MacDonald, R.J.3    Rutter, W.J.4
  • 8
    • 0028833699 scopus 로고
    • Structural requirements for dimerization, glycosylation, secretion, and biological function of VPF/VEGF
    • Claffey, K.P., D.R. Senger, and B.M. Spiegelman. 1995. Structural requirements for dimerization, glycosylation, secretion, and biological function of VPF/VEGF. Biochim. Biophys. Acta. 1246:1-9.
    • (1995) Biochim. Biophys. Acta , vol.1246 , pp. 1-9
    • Claffey, K.P.1    Senger, D.R.2    Spiegelman, B.M.3
  • 9
    • 27144449766 scopus 로고    scopus 로고
    • Domains and maturation processes that regulate the activity of ADAMTS-2, a metalloproteinase cleaving the aminopropeptide of fibrillar procollagens types I-III and V
    • Colige, A., F. Ruggiero, I. Vandenberghe, J. Dubail, F. Kesteloot, J. Van Beeumen, A. Beschin, L. Brys, C.M. Lapiere, and B. Nusgens. 2005. Domains and maturation processes that regulate the activity of ADAMTS-2, a metalloproteinase cleaving the aminopropeptide of fibrillar procollagens types I-III and V. J. Biol. Chem. 280:34397-34408.
    • (2005) J. Biol. Chem , vol.280 , pp. 34397-34408
    • Colige, A.1    Ruggiero, F.2    Vandenberghe, I.3    Dubail, J.4    Kesteloot, F.5    Van Beeumen, J.6    Beschin, A.7    Brys, L.8    Lapiere, C.M.9    Nusgens, B.10
  • 11
    • 0034104295 scopus 로고    scopus 로고
    • VPF/VEGF and the angiogenic response
    • Dvorak, H.F. 2000. VPF/VEGF and the angiogenic response. Semin. Perinatol. 24:75-78.
    • (2000) Semin. Perinatol , vol.24 , pp. 75-78
    • Dvorak, H.F.1
  • 12
    • 27944490875 scopus 로고    scopus 로고
    • VEGF as a therapeutic target in cancer
    • Ferrara, N. 2005. VEGF as a therapeutic target in cancer. Oncology. 69:11-16.
    • (2005) Oncology , vol.69 , pp. 11-16
    • Ferrara, N.1
  • 14
    • 0035870250 scopus 로고    scopus 로고
    • Down-regulation of vascular endothelial growth factor by tissue inhibitor of metalloproteinase-2: Effect on in vivo mammary tumor growth and angiogenesis
    • Hajitou, A., N.E. Sounni, L. Devy, C. Grignet-Debrus, J.M. Lewalle, H. Li, C.F. Deroanne, H. Lu, A. Colige, and B.V. Nusgens, et al. 2001. Down-regulation of vascular endothelial growth factor by tissue inhibitor of metalloproteinase-2: effect on in vivo mammary tumor growth and angiogenesis. Cancer Res. 61:3450-3457.
    • (2001) Cancer Res , vol.61 , pp. 3450-3457
    • Hajitou, A.1    Sounni, N.E.2    Devy, L.3    Grignet-Debrus, C.4    Lewalle, J.M.5    Li, H.6    Deroanne, C.F.7    Lu, H.8    Colige, A.9    Nusgens, B.V.10
  • 16
    • 0026395163 scopus 로고
    • The vascular endothelial growth factor family: Identification of a fourth molecular species and characterization of alternative splicing of RNA
    • Houck, K.A., N. Ferrara, J. Winer, G. Cachianes, B. Li, and D.W. Leung. 1991. The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA. Mol. Endocrinol. 5:1806-1814.
    • (1991) Mol. Endocrinol , vol.5 , pp. 1806-1814
    • Houck, K.A.1    Ferrara, N.2    Winer, J.3    Cachianes, G.4    Li, B.5    Leung, D.W.6
  • 17
    • 0032587138 scopus 로고    scopus 로고
    • Human Muller cells express VEGF183, a novel spliced variant of vascular endothelial growth factor
    • Jingjing, L., Y. Xue, N. Agarwal, and R.S. Roque. 1999. Human Muller cells express VEGF183, a novel spliced variant of vascular endothelial growth factor. Invest. Ophthalmol. Vis. Sci. 40:752-759.
    • (1999) Invest. Ophthalmol. Vis. Sci , vol.40 , pp. 752-759
    • Jingjing, L.1    Xue, Y.2    Agarwal, N.3    Roque, R.S.4
  • 19
    • 0029937679 scopus 로고    scopus 로고
    • The carboxyl-terminal domain (111-165) of vascular endothelial growth factor is critical for its mitogenic potency
    • Keyt, B.A., L.T. Berleau, H.V. Nguyen, H. Chen, H. Heinsohn, R. Vandlen, and N. Ferrara. 1996. The carboxyl-terminal domain (111-165) of vascular endothelial growth factor is critical for its mitogenic potency. J. Biol. Chem. 271:7788-7795.
    • (1996) J. Biol. Chem , vol.271 , pp. 7788-7795
    • Keyt, B.A.1    Berleau, L.T.2    Nguyen, H.V.3    Chen, H.4    Heinsohn, H.5    Vandlen, R.6    Ferrara, N.7
  • 20
    • 0034750658 scopus 로고    scopus 로고
    • Distinct pathways in the over-expression of matrix metalloproteinases in human fibroblasts by relaxation of mechanical tension
    • Lambert, C.A., A.C. Colige, C. Munaut, C.M. Lapiere, and B.V. Nusgens. 2001. Distinct pathways in the over-expression of matrix metalloproteinases in human fibroblasts by relaxation of mechanical tension. Matrix Biol. 20:397-408.
    • (2001) Matrix Biol , vol.20 , pp. 397-408
    • Lambert, C.A.1    Colige, A.C.2    Munaut, C.3    Lapiere, C.M.4    Nusgens, B.V.5
  • 22
    • 0037032431 scopus 로고    scopus 로고
    • Generation of a novel proteolysis resistant vascular endothelial growth factor165 variant by a site-directed mutation at the plasmin sensitive cleavage site
    • Lauer, G., S. Sollberg, M. Cole, T. Krieg, and S.A. Eming. 2002. Generation of a novel proteolysis resistant vascular endothelial growth factor165 variant by a site-directed mutation at the plasmin sensitive cleavage site. FEBS Lett. 531:309-313.
    • (2002) FEBS Lett , vol.531 , pp. 309-313
    • Lauer, G.1    Sollberg, S.2    Cole, M.3    Krieg, T.4    Eming, S.A.5
  • 23
    • 22344437713 scopus 로고    scopus 로고
    • Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors
    • Lee, S., S.M. Jilani, G.V. Nikolova, D. Carpizo, and M.L. Iruela-Arispe. 2005. Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors. J. Cell Biol. 169:681-691.
    • (2005) J. Cell Biol , vol.169 , pp. 681-691
    • Lee, S.1    Jilani, S.M.2    Nikolova, G.V.3    Carpizo, D.4    Iruela-Arispe, M.L.5
  • 24
    • 0034667464 scopus 로고    scopus 로고
    • Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth factor expression in human glioblastoma cells via a pathway involving phosphatidylinositol 3′-kinase and distinct from that induced by hypoxia
    • Maity, A., N. Pore, J. Lee, D. Solomon, and D.M. O'Rourke. 2000. Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth factor expression in human glioblastoma cells via a pathway involving phosphatidylinositol 3′-kinase and distinct from that induced by hypoxia. Cancer Res. 60:5879-5886.
    • (2000) Cancer Res , vol.60 , pp. 5879-5886
    • Maity, A.1    Pore, N.2    Lee, J.3    Solomon, D.4    O'Rourke, D.M.5
  • 26
    • 0027751890 scopus 로고
    • The vascular endothelial growth factor (VEGF) isoforms: Differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF
    • Park, J.E., G.A. Keller, and N. Ferrara. 1993. The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF. Mol. Biol. Cell. 4:1317-1326.
    • (1993) Mol. Biol. Cell , vol.4 , pp. 1317-1326
    • Park, J.E.1    Keller, G.A.2    Ferrara, N.3
  • 28
    • 0035062394 scopus 로고    scopus 로고
    • The splice variants of vascular endothelial growth factor (VEGF) and their receptors
    • Robinson, C.J., and S.E. Stringer. 2001. The splice variants of vascular endothelial growth factor (VEGF) and their receptors. J. Cell Sci. 114:853-865.
    • (2001) J. Cell Sci , vol.114 , pp. 853-865
    • Robinson, C.J.1    Stringer, S.E.2
  • 31
    • 0031438075 scopus 로고    scopus 로고
    • Inhibition of vascular endothelial growth factor (VEGF)-induced endothelial cell proliferation by a peptide corresponding to the exon 7-encoded domain of VEGF165
    • Soker, S., S. Gollamudi-Payne, H. Fidder, H. Charmahelli, and M. Klagsbrun. 1997. Inhibition of vascular endothelial growth factor (VEGF)-induced endothelial cell proliferation by a peptide corresponding to the exon 7-encoded domain of VEGF165. J. Biol. Chem. 272:31582-31588.
    • (1997) J. Biol. Chem , vol.272 , pp. 31582-31588
    • Soker, S.1    Gollamudi-Payne, S.2    Fidder, H.3    Charmahelli, H.4    Klagsbrun, M.5
  • 32
    • 0032549799 scopus 로고    scopus 로고
    • Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
    • Soker, S., S. Takashima, H.Q. Miao, G. Neufeld, and M. Klagsbrun. 1998. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell. 92:735-745.
    • (1998) Cell , vol.92 , pp. 735-745
    • Soker, S.1    Takashima, S.2    Miao, H.Q.3    Neufeld, G.4    Klagsbrun, M.5
  • 33
  • 35
    • 0029082384 scopus 로고
    • Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes
    • Stein, I., M. Neeman, D. Shweiki, A. Itin, and E. Keshet. 1995. Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes. Mol. Cell. Biol. 15:5363-5368.
    • (1995) Mol. Cell. Biol , vol.15 , pp. 5363-5368
    • Stein, I.1    Neeman, M.2    Shweiki, D.3    Itin, A.4    Keshet, E.5
  • 37
    • 0027997863 scopus 로고
    • Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor
    • Waltenberger, J., L. Claesson-Welsh, A. Siegbahn, M. Shibuya, and C.H. Heldin. 1994. Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor. J. Biol. Chem. 269:26988-26995.
    • (1994) J. Biol. Chem , vol.269 , pp. 26988-26995
    • Waltenberger, J.1    Claesson-Welsh, L.2    Siegbahn, A.3    Shibuya, M.4    Heldin, C.H.5
  • 38
    • 0032884545 scopus 로고    scopus 로고
    • Heterogeneous vascular endothelial growth factor (VEGF) isoform mRNA and receptor mRNA expression in human glomeruli, and the identification of VEGF148 mRNA, a novel truncated splice variant
    • Whittle, C., K. Gillespie, R. Harrison, P.W. Mathieson, and S. Harper. 1999. Heterogeneous vascular endothelial growth factor (VEGF) isoform mRNA and receptor mRNA expression in human glomeruli, and the identification of VEGF148 mRNA, a novel truncated splice variant. Clin. Sci. (Lond.). 97:303-312.
    • (1999) Clin. Sci. (Lond.) , vol.97 , pp. 303-312
    • Whittle, C.1    Gillespie, K.2    Harrison, R.3    Mathieson, P.W.4    Harper, S.5
  • 39
    • 5644294560 scopus 로고    scopus 로고
    • Therapeutic myocardial angiogenesis with vascular endothelial growth factors
    • Yoon, Y.S., I.A. Johnson, J.S. Park, L. Diaz, and D.W. Losordo. 2004. Therapeutic myocardial angiogenesis with vascular endothelial growth factors. Mol. Cell. Biochem. 264:63-74.
    • (2004) Mol. Cell. Biochem , vol.264 , pp. 63-74
    • Yoon, Y.S.1    Johnson, I.A.2    Park, J.S.3    Diaz, L.4    Losordo, D.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.