Cell surface association of matrix metalloproteinase-9 (gelatinase B)

Cancer and Metastasis Reviews

Volumn 22, Issue 2-3, 2003, Pages 153-166

  Fridman, Rafael ^a,b   Toth, Marta ^a   Chvyrkova, Irina ^a   Meroueh, Samy O ^b   Mobashery, Shahriar ^b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

Cell surface binding; Matrix metalloproteinase; Protease; Zymogen

Indexed keywords

GELATINASE B; HERMES ANTIGEN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MEMBRANE PROTEIN; PROTEINASE;

ANGIOGENESIS; CANCER INVASION; CELL SURFACE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME STRUCTURE; EXTRACELLULAR MATRIX; HUMAN; METASTASIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN INTERACTION; REVIEW; STROMA CELL; TUMOR CELL;

CELL MEMBRANE; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; HUMANS; MATRIX METALLOPROTEINASE 9; RECEPTORS, CELL SURFACE;

EID: 0038702661     PISSN: 01677659     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1023091214123     Document Type: Review

References (79)

1. Huang S, Van Arsdall M, Tedjarati S, McCarty M, Wu W, Langley R, Fidler IJ: Contributions of stromal metalloproteinase-9 to angiogenesis and growth of human ovarian carcinoma in mice. J Natl Cancer Inst 94: 1134-1142, 2002
2. Bergers G, Brekken R, McMahon G, Vu TH, Itoh T, Tamaki K, Tanzawa K, Thorpe P, Itohara S, Werb Z, Hanahan D: Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat Cell Biol 2: 737-744, 2000
3. Coussens LM, Tinkle CL, Hanahan D, Werb Z: MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell 103: 481-490, 2000
4. McCawley LJ, Matrisian LM: Matrix metalloproteinases: They're not just for matrix anymore! Curr Opin Cell Biol 13: 534-540, 2001
5. McQuibban GA, Gong JH, Tam EM, McCulloch CA, Clark-Lewis I, Overall CM: Inflammation dampened by gelatinase A cleavage of monocyte chemoanractant protein-3. Science 289: 1202-1206, 2000
6. Egeblad M, Werb Z: New functions for the matrix metalloproteinases in cancer progression. Nature Rev Cancer 2: 161-174, 2002
7. Ochieng J, Fridman R, Nangia-Makker P, Kleiner DE, Liotta LA, Stetler-Stevenson WG, Raz A: Galectin-3 is a novel substrate for human matrix metalloproteinases-2 and -9. Biochemistry 33: 14109-14114, 1994
8. Yu Q, Stamenkovic I: Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis. Genes Dev 14: 163-176, 2000
9. Patterson BC, Sang QA: Angiostatin-converting enzyme activities of human matrilysin (MMP-7) and gelatinase B/type IV collagenase (MMP-9). J Biol Chem 272: 28823-28825, 1997
10. Heissig B, Hattori K, Dias S, Friedrich M, Ferris B, Hackett NR, Crystal RG, Besmer P, Lyden D, Moore MA, Werb Z, Rafii S: Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell 109: 625-637, 2002
11. Belaaouaj AA, Li A, Wun TC, Welgus HG, Shapiro SD: Matrix metalloproteinases cleave tissue factor pathway inhibitor. Effects on coagulation. J Biol Chem 275: 27123-27128, 2000
12. Werb Z: ECM and cell surface proteolysis: Regulating cellular ecology. Cell 91: 439-442, 1997
13. Elkins PA, Ho YS, Smith WW, Janson CA, D'Alessio KJ, McQueney MS, Cummings MD, Romanic AM: Structure of the C-terminally truncated human ProMMP9, a gelatin-binding matrix metalloproteinase. Acta Crystallogr D Biol Crystallogr 58: 1182-1192, 2002
14. Morgunova E, Tuuttila A, Bergmann U, Isupov M, Lindqvist Y, Schneider G, Tryggvason K: Structure of human pro-matrix metalloproteinase-2: Activation mechanism revealed. Science 284: 1667-1670, 1999
15. Van Wart HE, Birkedal-Hansen H: The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family. Proc Natl Acad Sci USA 87: 5578-5582, 1990
16. Kotra LP, Cross JB, Shimura Y, Fridman R, Schlegel HB, Mobashery S: Insight into the complex and dynamic process of activation of matrix metalloproteinases. J Am Chem Soc 123: 3108-3113, 2001
17. Rowsell S, Hawtin P, Minshull CA, Jepson H, Brockbank SM, Barratt DG, Slater AM, McPheat WL, Waterson D, Henney AM, Pauptit RA. Crystal structure of human MMP9 in complex with a reverse hydroxamate inhibitor. J Mol Biol 319: 173-181, 2002
18. Stocker W, Bode W: Structural features of a superfamily of zinc-endopeptidases: the metzincins. Curr Opin Struct Biol 5: 383-390, 1995
19. Bode W, Gomis-Ruth FX, Stockler W: Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Metturn) and topologies and should be grouped into a common family, the 'metzincins'. FEBS Lett 331: 134-140, 1993
20. Briknarova K, Grishaev A, Banyai L, Tordai H, Patthy L, Llinas M: The second type II module from human matrix metalloproteinase 2: Structure, function and dynamics. Structure Fold Des 7: 1235-1245, 1999
21. Li J, Brick P, Blow DM: Structure of full-length porcine synovial collagenase reveals a C-terminal domain containing calcium-linked, four-bladed beta-propeller. Structure 3: 541, 1995
22. Libson AM, Gittis AG, Collier IE, Marmer BL, Goldberg GI, Lattman EE: Crystal structure of the haemopexin-like C-terminal domain of gelatinase A. Nat Struct Biol 2: 938-942, 1995
23. Gomis-Ruth FX, Gohlke U, Betz M, Knauper V, Murphy G, Lopez-Otin C, Bode W: The helping hand of collagenase-3 (MMP-13): 2.7 A crystal structure of its C-terminal haemopexin-like domain. J Mol Biol 264: 556-566, 1996
24. Cha H, Kopetzki E, Huber R, Lanzendorfer M, Brandstetter H: Structural basis of the adaptive molecular recognition by MMP9. J Mol Biol 320: 1065-1079, 2002
25. Goldberg GI, Marmer BL, Grant GA, Eisen AZ, Wilhelm S, He CS: Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2. Proc Natl Acad Sci USA 86: 8207-8211, 1989
26. Butler GS, Apte SS, Willenbrock F, Murphy G: Human tissue inhibitor of metalloproteinases 3 interacts with both the N- and C-terminal domains of gelatinases A and B. Regulation by polyanions. J Biol Chem 274: 10846-10851, 1999
27. Olson MW, Gervasi DC, Mobashery S, Fridman R: Kinetic analysis of the binding of human matrix metalloproteinase-2 and -9 to tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2. J Biol Chem 272: 29975-29983, 1997
28. Kotra LP, Zhang L, Fridman R, Orlando R, Mobashery S: Glycosylation pattern of the Zymogenic Form of Human Matrix Metalloproteinase-9. Bioorganic Chemistry 5: 356-370, 2002
29. Mattu TS, Royle L, Langridge J, Wormald MR, Van den Steen PE, Van Damme J, Opdenakker G, Harvey DJ, Dwek RA, Rudd PM: O-glycan analysis of natural human neutrophil gelatinase B using a combination of normal phase-HPLC and online tandem mass spectrometry: Implications for the domain organization of the enzyme. Biochemistry 39: 15695-15704, 2000
30. Springman EB, Angleton EL, Birkedal-Hansen H, Van Wart HE: Multiple modes of activation of latent human fibroblast collagenase: Evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation. Proc Natl Acad Sci USA 87: 364-368, 1990
31. Ogata Y, Enghild JJ, Nagase H: Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9. J Biol Chem 267: 3581-3584, 1992
32. O'Connell JP, Willenbrock F, Docherty AJ, Eaton D, Murphy G: Analysis of the role of the COOH-terminal domain in the activation, proteolytic activity, and tissue inhibitor of metalloproteinase interactions of gelatinase B. J Biol Chem 269: 14967-14973, 1994
33. Olson MW, Bernardo MM, Pietila M, Gervasi DC, Toth M, Kotra LP, Massova I, Mobashery S, Fridman R: Characterization of the monomeric and dimeric forms of latent and active matrix metalloproteinase-9. Differential rates for activation by stromelysin 1. J Biol Chem 275: 2661-2668, 2000
34. Okada Y, Gonoji Y, Naka K, Tomita K, Nakanishi I, Iwata K, Yamashita K, Hayakawa T: Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) from HT 1080 human fibrosarcoma cells. Purification and activation of the precursor and enzymic properties. J Biol Chem 267: 21712-21719, 1992
35. Fridman R, Toth M, Pena D, Mobashery S: Activation of progelatinase B (MMP-9) by gelatinase A (MMP-2). Cancer Res 55: 2548-2555, 1995
36. von Bredow DC, Cress AE, Howard EW, Bowden GT, Nagle RB: Activation of gelatinase-tissue-inhibitors-of-metalloproteinase complexes by matrilysin. Biochem J 331 (Pt 3): 965-972, 1998
37. Knauper V, Smith B, Lopez-Otin C, Murphy G: Activation of progelatinase B (proMMP-9) by active collagenase-3 (MMP-13). Eur J Biochem 248: 369-373, 1997
38. Ramos-DeSimone N, Hahn-Dantona E, Sipley J, Nagase H, French DL, Quigley JP: Activation of matrix metalloproteinase-9 (MMP-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion. J Biol Chem 274: 13066-13076, 1999
39. Strongin AY, Collier I, Bannikov G, Marmer BL, Grant GA, Goldberg GI: Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease. J Biol Chem 270: 5331-5338, 1995
40. Knauper V, Will H, Lopez-Otin C, Smith B, Atkinson SJ, Stanton H, Hembry RM, Murphy G: Cellular mechanisms for human procollagenase-3 (MMP-13) activation. Evidence that MT1-MMP (MMP-14) and gelatinase a (MMP-2) are able to generate active enzyme. J Biol Chem 271: 17124-17131, 1996
41. Han YP, Nien YD, Garner WL: Tumor necrosis factor-alpha-induced proteolytic activation of pro-matrix metalloproteinase-9 by human skin is controlled by down-regulating tissue inhibitor of metalloproteinase-1 and mediated by tissue-associated chymotrypsin-like proteinase. J Biol Chem 277: 27319-27327, 2002
42. Sorsa T, Salo T, Koivunen E, Tyynela J, Konttinen YT, Bergmann U, Tuuttila A, Niemi E, Teronen O, Heikkila P, Tschesche H, Leinonen J, Osman S, Stenman UH: Activation of type IV procollagenases by human tumor-associated trypsin-2. J Biol Chem 272: 21067-21074, 1997
43. Fang KC, Raymond WW, Blount JL, Caughey GH: Dog mast cell alpha-chymase activates progelatinase B by cleaving the Phe88-Gln89 and Phe91-Glu92 bonds of the catalytic domain. J Biol Chem 272: 25628-25635, 1997
44. Coussens LM, Raymond WW, Bergers G, Laig-Webster M, Behrendtsen O, Werb Z, Caughey GH, Hanahan D: Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis. Genes Dev 13: 1382-1397, 1999
45. Gervasi DC, Raz A, Dehem M, Yang M, Kurkinen M, Fridman R: Carbohydrate-mediated regulation of matrix metalloproteinase-2 activation in normal human fibroblasts and fibrosarcoma cells. Biochem Biophys Res Commun 228: 530-538, 1996
46. Butler GS, Butler MJ, Atkinson SJ, Will H, Tamura T, van Westrum SS, Crabbe T, Clements J, d'Ortho MP, Murphy G: The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study. J Biol Chem 273: 871-880, 1998
47. Toth M, Gervasi DC, Fridman R: Phorbol ester-induced cell surface association of matrix metalloproteinase-9 in human MCF10A breast epithelial cells. Cancer Res 57: 3159-3167, 1997
48. Okamoto T, Akaike T, Sawa T, Miyamoto Y, van der Vliet A, Maeda H: Activation of matrix metalloproteinases by peroxynitrite-induced protein S-glutathiolation via disulfide S-oxide formation. J Biol Chem 276: 29596-29602, 2001
49. Gu Z, Kaul M, Yan B, Kridel SJ, Cui J, Strongin A, Smith JW, Liddington RC, Lipton SA: S-nitrosylation of matrix metalloproteinases: Signaling pathway to neuronal cell death. Science 297: 1186-1190, 2002
50. Bannikov GA, Karelina TV, Collier IE, Marmer BL, Goldberg GI: Substrate binding of gelatinase B induces its enzymatic activity in the presence of intact propeptide. J Biol Chem 277: 16022-16027, 2002
51. Toth M, Fridman R: Assessment of gelatinases by gelatin zymography. In: S. A. Brooks, U. Schumacher eds. Metastasis Research Protocols, Vol. 1. Totowa, Humana Press, New Jersey, 2001, pp 163-174
52. Gaudin P, Berthier S, Barro C, Zaoui P, Morel F: Proteolytic potential of human neutrophil membranes. Eur J Cell Biol 72: 345-351, 1997
53. Olson MW, Toth M, Gervasi DC, Sado Y, Ninomiya Y, Fridman R: High affinity binding of latent matrix metalloproteinase-9 to the alpha2(IV) chain of collagen IV. J Biol Chem 273: 10672-10681, 1998
54. Partridge CA, Phillips PG, Niedbala MJ, Jeffrey JJ: Localization and activation of type IV collagenase/gelatinase at endothelial focal contacts. Am J Physiol 272: L813-822, 1997
55. Nguyen M, Arkell J, Jackson CJ: Active and tissue inhibitor of matrix metalloproteinase-free gelatinase B accumulates within human microvascular endothelial vesicles. J Biol Chem 273: 5400-5404, 1998
56. Taraboletti G, D'Ascenzo S, Borsotti P, Giavazzi R, Pavan A, Dolo V: Shedding of the matrix metalloproteinases MMP-2, MMP-9, and MT1-MMP as membrane vesicleassociated components by endothelial cells. Am J Pathol 160: 673-680, 2002
57. Makela M, Salo T, Larjava H: MMP-9 from TNF alpha-stimulated keratinocytes binds to cell membranes and type I collagen: A cause for extended matrix degradation in inflammation? Biochem Biophys Res Commun 253: 325-335, 1998
58. Mira E, Manes S, Lacalle RA, Marquez G, Martinez AC: Insulin-like growth factor I-triggered cell migration and invasion are mediated by matrix metalloproteinase-9. Endocrinology 140: 1657-1664, 1999
59. Zucker S, Moll UM, Lysik RM, DiMassimo El, Stetler-Stevenson WG, Liotta LA, Schwedes JW: Extraction of type-IV collagenase/gelatinase from plasma membranes of human cancer cells. Int J Cancer 45: 1137-1142, 1990
60. Ellerbroek SM, Halbleib JM, Benavidez M, Warmka JK, Wattenberg EV, Stack MS, Hudson LG: Phosphatidylinositol 3-kinase activity in epidermal growth factor-stimulated matrix metalloproteinase-9 production and cell surface association. Cancer Res 61: 1855-1861, 2001
61. Festuccia C, Angelucci A, Gravina GL, Villanova I, Teti A, Albini A, Bologna M, Abini A: Osteoblast-derived TGF-beta1 modulates matrix degrading protease expression and activity in prostate cancer cells. Int J Cancer 85: 407-415, 2000
62. Mazzieri R, Masiero L, Zanetta L, Monea S, Onisto M, Garbisa S, Mignatti P: Control of type IV collagenase activity by components of the urokinase-plasmin system: A regulatory mechanism with cell-bound reactants. Embo J 16: 2319-2332, 1997
63. Ginestra A, Monea S, Seghezzi G, Dolo V, Nagase H, Mignatti P, Vittorelli ML: Urokinase plasminogen activator and gelatinases are associated with membrane vesicles shed by human HT1080 fibrosarcoma cells. J Biol Chem 272: 17216-17222, 1997
64. Yu Q, Stamenkovic I: Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion. Genes Dev 13: 35-48, 1999
65. Visscher DW, Hoyhtya M, Ottosen SK, Liang CM, Sarkar FH, Crissman JD, Fridman R: Enhanced expression of tissue inhibitor of metalloproteinase-2 (TIMP-2) in the stroma of breast carcinomas correlates with tumor recurrence. Int J Cancer 59: 339-344, 1994
66. Karelina TV, Hruza GJ, Goldberg GI, Eisen AZ: Localization of 92-kDa type IV collagenase in buman skin tumors: comparison with normal human fetal and adult skin. J Invest Dermatol 100: 159-165, 1993
67. Legrand C, Gilles C, Zahm JM, Polette M, Buisson AC, Kaplan H, Birembaut P, Tournier JM: Airway epithelial cell migration dynamics. MMP-9 role in cell-extracellular matrix remodeling. J Cell Biol 146: 517-529, 1999
68. Toth M, Sado Y, Ninomiya Y, Fridman R: Biosynthesis of alpha2(IV) and alpha1(IV) chains of collagen IV and interactions with matrix metalloproteinase-9. J Cell Physiol 180: 131-139, 1999
69. Roeb E, Schleinkofer K, Kernebeck T, Potsch S, Jansen B, Behrmann I, Matern S, Grotzinger J: The MMP-9 hemopexin domain is a novel gelatin binding domain and acts as an antagonist. J Biol Chem 2002
70. Bourguignon LY, Gunja-Smith Z, Iida N, Zhu HB, Young LJ, Muller WJ, Cardiff RD: CD44v(3,8-10) is involved in cytoskeleton-mediated tumor cell migration and matrix metalloproteinase (MMP-9) association in metastatic breast cancer cells. J Cell Physiol 176: 206-215, 1998
71. Goodison S, Urquidi V, Tarin D: CD44 cell adhesion molecules. Mol Pathol 52: 189-196, 1999
72. Overall CM, Wrana JL, Sodek J: Independent regulation of collagenase, 72-kDa progelatinase, and metalloendoproteinase inhibitor expression in human fibroblasts by transforming growth factor-beta. J Biol Chem 264: 1860-1869, 1989
73. Herz J, Strickland DK: LRP: A multifunctional scavenger and signaling receptor. J Clin Invest 108: 779-784, 2001
74. Takahashi C, Sheng Z, Horan TP, Kitayama H, Maki M, Hitomi K, Kitaura Y, Takai S, Sasahara RM, Horimoto A, Ikawa Y, Ratzkin BJ, Arakawa T, Noda M: Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the membrane-anchored glycoprotein RECK. Proc Natl Acad Sci USA 95: 13221-13226, 1998
75. Oh J, Takahashi R, Kondo S, Mizoguchi A, Adachi E, Sasahara RM, Nishimura S, Imamura Y, Kitayama H, Alexander DB, Ide C, Horan TP, Arakawa T, Yoshida H, Nishikawa S, Itoh Y, Seiki M, Itohara S, Takahashi C, Noda M: The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis. Cell 107: 789-800, 2001
76. Hahn-Dantona E, Ruiz JF, Bornstein P, Strickland DK: The low density lipoprotein receptor-related protein modulates levels of matrix metalloproteinase 9 (MMP-9) by mediating its cellular catabolism. J Biol Chem 276: 15498-15503, 2001
77. Hahn-Dantona E, Ramos-DeSimone N, Sipley J, Nagase H, French DL, Quigley JP: Activation of proMMP-9 by a plasmin/MMP-3 cascade in a tumor cell model. Regulation by tissue inhibitors of metalloproteinases. Ann NY Acad Sci 878: 372-387, 1999
78. Mori H, Tomari T, Koshikawa N, Kajita M, Itoy Y, Sato H, Tojo H, Yana I, Sciki M: CD44 directs membrane-type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin-like domain. EMBO J 21: 3949-3959, 2002.
79. Takahashi C, Sheng Z, Horan TP, Kitayama H, Maki M, Hitomi K, Kitaura Y, Takai S, Sasahara RM, Horimoto A, Ikawa Y, Ratzkin BJ, Arakawa T, Noda M: Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the membrane-anchored glycoprotein RECK. Proc Natl Acad Sci USA 95: 13221-13226, 1998.